Features of the morphological structure of plants and biochemical properties of introduced and domestic varieties of Cannabis sativa L. by А. С. Полякова, Л. М. Горшкова, Д. Б. Рахметов

“…According to the developed own classification (THC + KBN): CBD, varieties with a predominant CBD content ‘Hlukhivskyi 46’, ‘Zolotoniski 15’, ‘Hliana’ which are of significant medicinal value were identified.…”
Get full text

Leukopenia and thrombocytopenia in dengue patients: a cross-sectional study from a tertiary hospitals in Koshi Province, Nepal by Birendra Prasad Gupta, Surendra Uranw, Vivek Prasad Gupta, Elisha Deuba, Ajay Kumar Sah, Santosh Chaudhary, Chandramani Wagle

“…Leukopenia showed a significant association with DWS (χ²=5.481, p = 0.019; Cramér’s V = 0.13), with adjusted residuals highlighting its stronger link to DWS (AR = 3.40). Thrombocytopenia, though prevalent, was more common in milder cases (DWWS). …”
Get full text

Large Language Model Approach for Zero-Shot Information Extraction and Clustering of Japanese Radiology Reports: Algorithm Development and Validation by Yosuke Yamagishi, Yuta Nakamura, Shouhei Hanaoka, Osamu Abe

“…ResultsThe tumor size was accurately identified in 99 out of 135 reports (73.3%), with errors in 36 reports (26.7%), primarily due to missing or incorrect size information. …”
Get full text

APPLICATION OF ARTIFICIAL NEURAL NETWORKS TO PREDICT RAILWAY SWITCH DURABILITY by Łukasz GIBAŁA, Jarosław KONIECZNY

“…Using the prepared data set (changes in values of nominal dimensions in characteristic sections of 15 railway switches), we created three variants of railway switch classifications. …”
Get full text

Modeling Spatial and Temporal Changes in Land-Uses and Land Cover of the Urmia Lake Basin Applying Cellular Automata and Markov Chain by Hadi Eskandari Damaneh, Hamid Gholami, Hassan Khosravi, Rasoul Mahdavi Najafabadi, Asadollah Khoorani, Gimmy Li

“…First, the land-use map was produced by the maximum likelihood classification method using the Landsat satellite imagery for the years 1998, 2008, and 2018. …”
Get full text

Genome-wide identification and expression of the HB gene family during overwintering in Korla pear (Pyrus sinkiangensis) by LIU Xiaoyan, WANG Lijuan, YANG Shenghui, LUO Guanghong, ZHU Jianbo

“…Transcriptome data analysis during three stages of the overwintering process in P. sinkiangensis revealed that 39 out of the 93 PsHB genes were differentially expressed. …”
Get full text

Detecting Postural Instability in Parkinson’s Disease From IMU-Based Objective Measures by Kendal Smith, Diego Torricelli, Miguel Gonzalez-Sanchez, Javier Ricardo Perez-Sanchez, Elisa Luque-Buzo, Francisco Grandas, Juan Miguel Marin, Jorge Andres Gomez-Garcia

“…To the best of our knowledge, this work represents the first extensive attempt to objectively quantify the pull test for this type of classification.…”
Get full text

Precision Oral Medicine: A DPR Segmentation and Transfer Learning Approach for Detecting Third Molar Compress Inferior Alveolar Nerve by Yuan-Jin Lin, Shih-Lun Chen, Yi-Cheng Mao, Tsung-Yi Chen, Cheng-Hao Peng, Tzu-Hsiang Tsai, Kuo-Chen Li, Chiung-An Chen, Wei-Chen Tu, Patricia Angela R. Abu

“…The third molar position localization method achieved an accuracy rate of 97.92%, compared to recent research at least improved by 3.6% accuracy. Subsequently, innovative edge masking and image enhancement methods improve classification accuracy by 4.3%, when supplemented with computed tomography scan images for further evaluation, the maximum accuracy reached 98.45%, representing a 4.5% improvement compared to previous studies. …”
Get full text

Comparison of INTERGROWTH- 21st and Fenton growth standards to assess size at birth and at discharge in preterm infants in the United Arab Emirates by Leila Cheikh Ismail, Maysm N. Mohamad, Eric O. Ohuma, Mahmoud S. ElHalik, Swarup K. Dash, Tareq M. Osaili, Hayder Hasan, Mona Hashim, Sheima T. Saleh, Rameez Al Daour, Simon R. Parker, Habiba I. Ali, Lily Stojanovska, Ayesha S. Al Dhaheri

“…Results A total of 1537 infants with a median birth gestation of 35.3 weeks, and a median birthweight of 2320 g were included. …”
Get full text

Sequence-structure based prediction of pathogenicity for amino acid substitutions in proteins associated with primary immunodeficiencies by Ekaterina S. Porfireva, Anton D. Zadorozhny, Anastasia V. Rudik, Dmitry A. Filimonov, Alexey A. Lagunin, Alexey A. Lagunin

“…In this study, we have developed classification sequence-structure-property relationships (SSPR) models for predicting the pathogenicity of amino acid substitutions (AAS) in 25 proteins associated with the most important and genetically studied PIDs and encoded genes: IL2RG, JAK3, RAG1, RAG2, ADA, DCLRE1C, CD40LG, WAS, ATM, STAT3, KMT2D, BTK, FOXP3, AIRE, FAS, ELANE, ITGB2, CYBB, G6PD, GATA2, STAT1, IFIH1, NLRP3, MEFV, and SERPING1.MethodsThe data on 4825 pathogenic and benign AASs in the selected proteins were extracted from ClinVar and gnomAD. …”
Get full text

Forecasting stroke and stroke-driven dementia in a rapidly ageing population: a model-based analysis of alternative projection scenarios for Ireland by Anne Hickey, Eithne Sexton, Frances Horgan, Kathleen E Bennett, Ronan Collins, Martin O'Flaherty, Suzanne Timmons, Chris Macey, David J. Williams

“…We used multiple data sources, including systematic review and observational evidence.Interventions Not applicable.Primary and secondary outcome measures We projected the incidence and prevalence of stroke (International Classification of Disease (ICD) codes I60–I61, I63–I64), poststroke dementia (Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-V) criteria) and poststroke disability (modified Rankin Scale 3–5).Results The stable scenario indicated a projected 85 834 stroke survivors in 2046 (95% uncertainty interval (UI)=82 366–89 655), an increase of 45.7% from 2022. …”
Get full text

Digital Health Technology Interventions for Improving Medication Safety: Systematic Review of Economic Evaluations by Widya Norma Insani, Neily Zakiyah, Irma Melyani Puspitasari, Muhammad Yorga Permana, Kankan Parmikanti, Endang Rusyaman, Auliya Abdurrohim Suwantika

“…MethodsA systematic search was conducted across 3 major electronic databases (ie, PubMed, Scopus, and EBSCOhost). …”
Get full text

Detection of urinary levels of matrix metalloproteinase-7 and tumor necrosis factor-like weak inducer of apoptosis in patients with IgA nephropathy and values in predicting disease... by Ma Yong-duo, Wang Cong, Li Hai-xiang, Wu Huan

“…ObjectiveTo explore the expressions of urinary matrix metalloproteinase-7 （MMP-7） and tumor necrosis factor-like weak inducer of apoptosis （TWEAK） in patients with IgA nephropathy （IgAN） and examine its predictive value.MethodsFrom January 2018 to March 2021，115 IgAN patients and 50 normal subjects （control group） were selected.Based upon the progress of IgAN，115 cases of IgAN patients were divided into two groups of IgAN progressive （<italic>n</italic>=42） and IgAN non-progressive （<italic>n</italic>=73）.According to the IgAN Oxford classification criteria，they were assigned into two groups of MEST-C≥3 （<italic>n</italic>=45） and MEST-C&lt;3 （<italic>n</italic>=70）.The levels of urinary MMP-7 and TWEAK were compared between two groups.Multivariate Logistic regression was utilized for analyzing the risk factors of IgAN progression.Receiver operating characteristic （ROC） curve was plotted for examining the values of urinary MMP-7 and TWEAK levels in predicting IgAN progression.ResultsThe levels of urinary MMP-7 （15.72±7.85 <italic>vs</italic> 6.92±0.53 ng/mL） and TWEAK were significantly higher in IgAN progressive group than those in IgAN non-progressive group ［（958.47±42.60） <italic>vs</italic> （206.73±15.18）ng/mL，<italic>P</italic>&lt;0.001］.The levels of urinary MMP-7 ［（23.92±9.27） <italic>vs</italic> （18.15±8.36） ng/mL］ and TWEAK ［（1408.70±71.15） <italic>vs</italic> （1036.28±50.72） ng/mL］ were significantly higher in MEST-C≥3 score group than those in MEST-C&lt;3 score group （<italic>P</italic>&lt;0.001）.Multivariate Logistic regression analysis indicated that elevated levels of MMP-7 ［<italic>OR</italic>=2.986 95%<italic>CI</italic>（2.146，-8.513）］ and TWEAK ［<italic>OR</italic>=3.370 95%<italic>CI</italic>（2.752，-10.118）］ were the risk factors affecting the progression of IgAN.Receiver operating characteristic （ROC） curve indicated that the area under the curve （AUC） of MMP-7 and TWEAK in predicting IgAN progression was 0.948 （95% <italic>CI </italic>0.885-0.997） with a sensitivity of 97.5% and a specificity of 85.0%.Correlation analysis indicated that the urinary levels of MMP-7 and TWEAK were significantly positively correlated with M，E，S and T （<italic>P</italic>&lt;0.001）.ConclusionThe elevated urinary levels of MMP-7 and TWEAK are the risk factors affecting the progression of IgAN.Both may be used as biological indicators for predicting the progression of IgAN.…”
Get full text

Territories -in- between by Alexander Wandl

“…The comparison with widely used urban-rural classifications shows that the notion of TiB has three advantages: (i) it maps the complexity of the spatial structure of urbanised areas on a regional scale, and thereby helps to overcome the prevalent idea that urbanised regions are characterised by a spatial gradient from urban centre(s) to rural periphery; (ii) it emphasises the network structure of territories-in-between and the underlying connectivity of places with different functions; and (iii) it raises awareness that in some parts of Europe a settlement pattern has developed that cannot be understood as either urban or rural. …”
Get full text

Risk Factors of Poor Prognosis after Whiplash Injury by Samy Suissa

“…In contrast, using the Quebec classification of signs and symptoms, the median recovery time varied from 17 to 123 days. …”
Get full text

Using Digital Phenotyping to Discriminate Unipolar Depression and Bipolar Disorder: Systematic Review by Rongrong Zhong, XiaoHui Wu, Jun Chen, Yiru Fang

“…Moreover, speech modalities or the integration of multiple modalities achieved better classification performance across UD, BD, and HC groups, although the specific contributing features remained unclear. …”
Get full text

Evaluating the Utility of Wearable Sensors for the Early Diagnosis of Parkinson Disease: Systematic Review by Hai Li, Massimiliano Zecca, Jiajun Huang

“…The inclusion criteria were as follows: (1) the study was observational or experimental, (2) wearable sensors were applied for the early diagnosis of PD, (3) participants were diagnosed with early-stage or prodromal PD, (4) the study included at least 10 participants with PD, and (5) the article was published between 2013 and 2023. …”
Get full text

Cyber security Enhancements with reinforcement learning: A zero-day vulnerabilityu identification perspective. by Muhammad Rehan Naeem, Rashid Amin, Muhammad Farhan, Faisal S Alsubaei, Eesa Alsolami, Muhammad D Zakaria

“…Gamma was also at 0.00, resulting in a very high level of precision within the forecast. MASE was 3.91 and SMAPE was 1.59, meaning that a very minimal percentage error existed within the forecast. …”
Get full text

Ultra-processed foods and coronary artery disease severity: a cross-sectional study of at-risk normal-weight and overweight patients undergoing elective angiography by Zeinab Ghorbani, Fatemeh Dashti, Sara Grafenauer, Samira Arami, Marjan Mahdavi-Roshan, Arsalan Salari

“…Overweight/obese participants in the higher UPF quartiles had approximately 2-3.5 times greater odds for severe-CAD than those in the 1st quartile (ORs (95%CIs): 3rd quartile 1.91 (1.14, 3.21); and 4th quartile: 3.53 (2.07, 5.99); P-for-trend < 0.001). …”
Get full text

Efficacy and safety of leflunomide in patients with rheumatoid arthritis in real-life clinical practice (results of the Russian multicenter surveillance study) by R.M. Balabanova, T.B. Dubinina, D.V. Goryachev, E.L. Shakhramanova, O.N. Anoshenkova, N.R. Degula

“…The study involved patients corresponding to the 1987 RA classification criteria, with varying disease duration. …”
Get full text