Association of Major Depression With Risk of Ischemic Heart Disease in a Mega‐Cohort of Chinese Adults: The China Kadoorie Biobank Study by Na Liu, Xiong‐Fei Pan, Canqing Yu, Jun Lv, Yu Guo, Zheng Bian, Ling Yang, Yiping Chen, Tangchun Wu, Zhengming Chen, An Pan, Liming Li

“…During 3 423 542 person‐years of follow‐up, 24 705 incident IHD cases were documented. …”
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Impact of Amerindian ancestry on clinical outcomes in Crohn’s disease and ulcerative colitis in a Latino population by Tamara Pérez-Jeldres, María Leonor Bustamante, Danilo Alvares, Manuel Alvarez-Lobos, Lajos Kalmer, Lorena Azocar, Roberto Segovia Melero, Gabriel Ascui, Nataly Aguilar, Ricardo Estela, Cristian Hernández-Rocha, Roberto Candia, Mauricio González, Verónica Silva, Andrés De La Vega, Elizabeth Arriagada, Carolina A. Serrano, Carolina Pávez-Ovalle, Carol Moraga Quinteros, Juan Francisco Miquel, Di Genova Alex

“…We used Chi-square and Fisher’s tests to analyze the relationship between phenotypes and ancestry proportions, calculating odds ratios (OR) and confidence intervals (CI). Logistic regression examined genetic variants associations with IBD outcomes, and classification models for predicting prolonged remission were developed using decision tree and random forest techniques. …”
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Estimation of the water content of needles under stress by Erannis jacobsoni Djak. via Sentinel-2 satellite remote sensing by Jiaze Guo, Xiaojun Huang, Xiaojun Huang, Xiaojun Huang, Debao Zhou, Junsheng Zhang, Gang Bao, Gang Bao, Siqin Tong, Siqin Tong, Yuhai Bao, Yuhai Bao, Dashzebeg Ganbat, Dorjsuren Altanchimeg, Davaadorj Enkhnasan, Mungunkhuyag Ariunaa

“…The accuracy of the method is verified by comparing the estimation results with field measurements, and the results are combined with the classifications of the leaf loss rate(LLR) to assess the severity of infestation.ResultsThe results indicate that: 1) When estimating LWCD and LWCF using the SVR and BP models, the SVR model demonstrated superior accuracy and stability (MAE for LWCF = 0.1477, RMSE = 0.17314; MAE for LWCD = 0.10507, RMSE = 0.14760). 2) The classification accuracies of LWCD and LWCF were notably higher in areas with light and medium damage, suggesting that these indices are effective indicators for assessing damage caused by Erannis jacobsoni Djak. and can serve as valuable tools for monitoring pest infestation and its progression. 3) Through precision evaluation and supplementary validation, the results show that LWCD is more stable and reliable than LWCF, demonstrating greater credibility, particularly in terms of MAE and RMSE, where LWCD exhibits lower values (MAE for LWCD = 0.10507, RMSE = 0.14760). …”
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Prognostic Value of G8 Geriatric Screening and Meet-URO Scores in Metastatic Renal Cell Carcinoma Patients Receiving First-Line Ipilimumab-Nivolumab Combination Immunotherapy by Ria Nagpal MB, BCh, BAO, Marina Campione PhD, Sara Elena Rebuzzi MD, Lucia Fratino MD, Pasquale Rescigno MD, Sergio Bracarda MD, Davide Bimbatti MD, Ugo De Giorgi MD, Matteo Santoni MD, Fabio Calabrò MD, Mimma Rizzo MD, Alessio Signori PhD, Diana Giannarelli PhD, Giuseppe Fornarini MD, Umberto Basso MD, Giuseppe Luigi Banna MD

“…This study aimed to evaluate the prognostic role of G8 within the context of the Meet-URO classification in mRCC patients treated with first-line ipilimumab-nivolumab. …”
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Measuring and estimation of suspended sediment variation using sediment rating curve approach in Mereg River by Sohila Aghabeigi Amin, Heidar Mirzaei

“…Measured floods have the peak flows from 1.38 to 49.40 m3/s covering a suitable range of low to high peak flows in this river. …”
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Critical predictors of heart transplant necessity in children with advanced DCM by Zubo Wu, Jiawei Shi, Hui Huang, Jie Liu, Qing Guo, Nianguo Dong, Jing Zhang, Wangzi Li, Lin Wang, Hua Peng

“…A univariate logistic regression analysis demonstrated that NYHA score [aOR (95%CI) = 2.78 (1.06–7.27), p = 0.037], Ascites [aOR (95%CI) = 12.93 (2.45–68.22), p = 0.003], and Left ventricular noncompaction [aOR (95%CI) = 3.73 (1.01–13.86), p = 0.048] were all significantly correlated with the Transplantation group. …”
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Joint analysis of single-cell RNA sequencing and bulk transcriptome reveals the heterogeneity of the urea cycle of astrocytes in glioblastoma by Minfeng Tong, Qi Tu, Lude Wang, Huahui Chen, Xing Wan, Zhijian Xu

“…The GSE138794 dataset was used to validate the results of single-cell classification. For bulk RNA-seq, univariate Cox and LASSO analyses were undertaken to screen prognostic genes, while multivariate Cox regression analysis was applied to set up a prognostic model. …”
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Associations between measures of network centrality and Johne's disease among dairy herds in Ontario, Canada by J. Reilly Comper, Karen J. Hand, Zvonimir Poljak, David Kelton, Amy L. Greer

“…However, herd size, region of herd, and previous high-risk JD classification were all positively associated with being classified as high-risk for JD. …”
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Association between low-density lipoprotein cholesterol levels and all-cause mortality in patients with coronary artery disease: a real-world analysis using data from an internatio... by Thiago Luis Scudeler, Leandro Menezes Alves da Costa, Rafael Amorim Belo Nunes, Rafael Otto Schneidewind, Thiago Midlej Brito, Daniel Castanho Genta Pereira, Roger Pereira de Oliveira, Gabriela Chaves Santana, Helio Castello, Marcelo José de Carvalho Cantarelli, Álvaro Avezum Junior

“…CAD patients were identified using the International Classification of Diseases, Tenth Revision (ICD-10) diagnosis code and stratified into six LDL-C categories: <50 mg/dL (cohort 1), 50–69.9 mg/dL (cohort 2), 70–99.9 mg/dL (cohort 3), 100–129.9 mg/dL (cohort 4), 130–159.9 mg/dL (cohort 5), and ≥ 160 mg/dL (cohort 6). …”
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Factors Influencing the Response of Patients with Infantile Epileptic Spasms Syndrome to ACTH as Repeated First-Line Therapy by Wenrong Ge, Ping Pang, Ziyan Zhang, Lin Wan, Guang Yang

“…A multifactorial regression model indicated that older age at first seizure and a short-term response to initial first-line treatment were associated with a higher likelihood of obtaining an initial response in the subsequent ACTH treatment (odds ratio [OR] 2.69, 95% confidence interval [CI] 1.39, 7.23, p = 0.014 and OR 5.41, 95% CI 1.48, 23.90, p = 0.016, respectively). …”
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A Nested Case-Control Study of Metabolically Defined Body Size Phenotypes and Risk of Colorectal Cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC). by Neil Murphy, Amanda J Cross, Mustapha Abubakar, Mazda Jenab, Krasimira Aleksandrova, Marie-Christine Boutron-Ruault, Laure Dossus, Antoine Racine, Tilman Kühn, Verena A Katzke, Anne Tjønneland, Kristina E N Petersen, Kim Overvad, J Ramón Quirós, Paula Jakszyn, Esther Molina-Montes, Miren Dorronsoro, José-María Huerta, Aurelio Barricarte, Kay-Tee Khaw, Nick Wareham, Ruth C Travis, Antonia Trichopoulou, Pagona Lagiou, Dimitrios Trichopoulos, Giovanna Masala, Vittorio Krogh, Rosario Tumino, Paolo Vineis, Salvatore Panico, H Bas Bueno-de-Mesquita, Peter D Siersema, Petra H Peeters, Bodil Ohlsson, Ulrika Ericson, Richard Palmqvist, Hanna Nyström, Elisabete Weiderpass, Guri Skeie, Heinz Freisling, So Yeon Kong, Kostas Tsilidis, David C Muller, Elio Riboli, Marc J Gunter

“…Therefore, a possible limitation of our analysis was that the classification of individuals as being hyperinsulinaemic-based on their C-peptide level-was arbitrary. …”
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The immune-related prognostic gene AIM2 promotes pancreatic cancer progression via inflammasome by Lin Liang, Yanhong Zhou, Yang Zhang, Shuangyan Ou, Zhijun Yuan, Hong Yi, Xia Yuan

“…Nine gene prognostic features were identified as the optimal IRGPs, which include six high-risk genes and three low-risk genes. Principal Component Analysis (PCA) demonstrated that this feature can effectively distinguish between high-risk and low-risk groups. …”
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Relationship between pharmacotherapy for major depressive disorder and healthcare utilisation in British Columbia, Canada: a retrospective population-based cohort by Sonya Cressman, Louisa Edwards, Kimberlyn McGrail, Stirling Bryan, Alison Hoens, Rohit Vijh, Sandra Peterson, Zeina Waheed, Mary Bunka, Nick Pang, Shahzad Ghanbarian, Gavin Wong, Linda Riches, Jehannine Austin

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Detecting Changes in Soil Fertility Properties Using Multispectral UAV Images and Machine Learning in Central Peru by Lucia Enriquez, Kevin Ortega, Dennis Ccopi, Claudia Rios, Julio Urquizo, Solanch Patricio, Lidiana Alejandro, Manuel Oliva-Cruz, Elgar Barboza, Samuel Pizarro

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Combining single-cell analysis and molecular docking techniques to construct a prognostic model for colon adenocarcinoma and uncovering inhibin subunit βb as a novel therapeutic ta... by Qinqing Wu, Qinqing Wu, Lu Ye, Yuwei Wu, Mengyu Zhao, Mengyu Zhao, Jiaxin Lu, Yanping Yu, Yanping Yu, Yixiao Niu, Yixiao Niu, Luxiao Zhang, Peijun Zuo, Peijun Zuo

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Functional goals and outcomes of rehabilitation within palliative care: a multicentre prospective cohort study by Matthew Maddocks, Lucy Fettes, Naomi Takemura, Joanne Bayly, Helena Talbot-Rice, Karen Turner, Rebecca Tiberini, Richard Harding, Fliss E.M. Murtagh, Richard J. Siegert, Irene J. Higginson, Stephen A. Ashford, Lynne Turner-Stokes

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Assessment of Relationship between Land Use Pattern and Spatial Distribution of Water Quality at the Watershed Scale: A Case Study of Maroon River Sub-basin by Fariba Hedayatzadeh, Alireza Ildoromi, Nasrin Hasanzadeh, Nader Bahramifar, Mahdi Banaee

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Regional and whole-brain neurofunctional alterations during pain empathic processing of physical but not affective pain in migraine patients by Dan Liu, Menghan Li, Heng Jiang, Yiqi Mi, Xiaolei Xu, Yali Zhou, Yaxian Hou, Yuquan Shen, Michael Maes, Xiao Xiao, Feng Zhou, Luca Giani, Keith M. Kendrick, Benjamin Becker, Stefania Ferraro

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Construction and validation of a prognostic nomogram model integrating machine learning-pathomics and clinical features in IDH-wildtype glioblastoma by Yaomin Li, Pei Ouyang, Zongliao Zheng, Jiapeng Deng, Aishun Guo, Weiwei Wang, Yawei Liu, Yuping Peng, Yankai Liao, Xiran Wang, Hai Wang, Zhaojun Wang, Zhitai Mo, Jianming Weng, Haiyan Xv, Xiaoxia Zheng, Junlu Liu, Yajuan Wang, Yongfu Cao, Guanglong Huang, Xian Zhang, Songtao Qi

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Predicting symptomatic carotid artery plaques with radiomics-based carotid perivascular adipose tissue characteristics: a multicenter, multiclassifier study by Ting Zhao, Guihan Lin, Weiyue Chen, Jianhua Wu, Weiming Hu, Lei Xu, Yongjun Chen, Yang Jing, Lin Shen, Shuiwei Xia, Chenying Lu, Minjiang Chen, Jiansong Ji, Weiqian Chen

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