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    Development of cell-based assay for detecting replication-competent adeno-associated virus by qPCR by Aishwarya Shevade, John S. Reeves, Hanne Bak, Andrew D. Tustian

    Published 2025-09-01
    “…Here, we have developed a sensitive, cell-based assay for detection of rcAAV in AAV8 preparations. …”
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    Immune Cell-Based versus Albumin-Based Ratios as Outcome Predictors in Critically Ill COVID-19 Patients by Zeba S, Surbatovic M, Udovicic I, Stanojevic I, Vojvodic D, Rondovic G, Mladenovic K, Abazovic T, Hasanovic A, Ilic AN, Abazovic D, Khan W, Djordjevic D

    Published 2025-01-01
    “…All the measured and calculated parameters were compared between survivors and nonsurvivors, with the outcome measure being hospital mortality.Results: Immune cell-based ratios [NLR - Neutrophil-to-Lymphocyte Ratio, MLR - Monocyte-to-Lymphocyte Ratio, PLR - Platelet-to-Lymphocyte Ratio, MPV - Mean Platelet Volume, MPV/PC - Mean Platelet Volume-to-Platelet Count Ratio, Derived (d-)NLR ratio - neutrophil count divided by the result of white blood cell (WBC) count – neutrophil count), N/LP - Neutrophil count x 100/Lymphocyte count x Platelet count, CLR – C-reactive protein (CRP)-to-Lymphocyte Ratio, CPR - CRP-to-Platelet Ratio, LLR - Lactate dehydrogenase (LDH)-to-Lymphocyte Ratio, Systemic Immune Inflammation Index (SII) - platelet x neutrophil/lymphocyte count, Systemic Inflammation Response Index (SIRI) - neutrophil x monocyte/lymphocyte count] were investigated. …”
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    Bone Marrow-Derived Cell Therapies to Heal Long-Bone Nonunions: A Systematic Review and Meta-Analysis—Which Is the Best Available Treatment? by Silvia Palombella, Silvia Lopa, Silvia Gianola, Luigi Zagra, Matteo Moretti, Arianna B. Lovati

    Published 2019-01-01
    “…Nonunions represent one of the major indications for clinical settings with stem cell-based therapies. The objective of this research was to systematically assess the current evidence for the efficacy of bone marrow-derived cell-based approaches associated or not with bone scaffolds for the treatment of nonunions. …”
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    Modeling Multicellular Systems Using Subcellular Elements by T. J. Newman

    Published 2005-07-01
    “…We present here a detailed description of the model, and use successive mean-field approximations to connect it to more coarse-grained approaches, such as discrete cell-based algorithms and coupled partial differential equations. …”
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    Quantification and Comprehensive Analysis of Mesenchymal Stromal Cells in Bone Marrow Samples from Sickle Cell Disease Patients with Osteonecrosis by Tiago O. Ribeiro, Paula B. Daltro, Gildasio Cerqueira Daltro, Songeli M. Freire, Roberto Meyer, Vitor Fortuna

    Published 2020-01-01
    “…We also compared expanded BM-MSC osteogenic differentiation, migration, and cytokine secretion potential between these groups. The mean total cell number, CFU-F count, and CD271+CD45-/low cells in BM mononuclear concentrate were significantly higher in SCD than in NS patients. …”
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    Differential expression of antibodies to NMDA receptor in anti-NMDA receptor encephalitis and in neuropsychiatric systemic lupus erythematosus by Shunsei Hirohata, Keiko Tanaka

    Published 2019-12-01
    “…Anti-NR2 and anti-NR1/NR2 were measured by ELISA and cell-based assay, respectively. The positivity for anti-NR2 was defined by a value exceeding mean+2 SD of normal healthy subjects.Results Anti-NR2 was positive in the sera of 19 of 31 patients with NPSLE (in 15 of 22 patients with diffuse NPSLE). …”
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