An Emerging Role for IQGAP1 in Regulating Protein Traffic by Mahasin Osman

“…Membrane traffic mediates infections by intracellular pathogens and a range of degenerative human diseases arise from dysfunctions in intracellular traffic; thus, elucidating the mechanisms of cellular traffic will be important in order to understand the basis of a wide range of inherited and acquired human diseases. …”
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Scorpion Venom and the Inflammatory Response by Vera L. Petricevich

“…Scorpion venoms consist of a complex of several toxins that exhibit a wide range of biological properties and actions, as well as chemical compositions, toxicity, and pharmacokinetic and pharmacodynamic characteristics. …”
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An Integrative Approach to Accurate Vehicle Logo Detection by Hao Pan, Bailing Zhang

“…The task is challenging considering the small target of logos and the wide range of variability in shape, color, and illumination. …”
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Using an Artificial Neural Network to Validate and Predict the Physical Properties of Self-Compacting Concrete by K. Thirumalai Raja, N. Jayanthi, Jule Leta Tesfaye, N. Nagaprasad, R. Krishnaraj, V. S. Kaushik

“…Experiments to determine compressive strength for a wider range of mixed prepositions will result in higher project expenses and delays. …”
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A Diathesis-Stress Model of Chronic Pain and Disability following Traumatic Injury by Dennis C Turk

“…One of the perplexing features of pain is the wide variability in patients' responses to ostensibly the same extent of physical pathology. A range of cognitive, affective and behavioural factors are related to the perception of pain, maintenance of pain and disability, exacerbation of pain and response to treatment. …”
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Biocatalytic enantioselective formation and ring-opening of oxetanes by Xia Hua, Yuan-Fei Wang, Xiao Jin, Hong-Yin Yu, Hui-Hui Wang, Yong-Zheng Chen, Nan-Wei Wan

“…Abstract Although biocatalysis offers complementary or alternative approaches to traditional synthetic methods, the limited range of available enzymatic reactions currently poses challenges in synthesizing a diverse array of desired compounds. …”
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Emerging Lung Cancer Therapeutic Targets Based on the Pathogenesis of Bone Metastases by Moses O. Oyewumi, Adnan Alazizi, Daniel Wehrung, Rami Manochakian, Fayez F. Safadi

“…Bone metastases can cause a wide range of symptoms that could impair quality of life of lung cancer patients and shorten their survival. …”
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The Role of Mannose-Binding Lectin in Severe Sepsis and Septic Shock by Gennaro De Pascale, Salvatore Lucio Cutuli, Mariano Alberto Pennisi, Massimo Antonelli

“…Mannose-binding lectin (MBL) is a serum protein that recognizes a wide range of pathogenic microorganisms and activates complement cascade via the antibody-independent pathway. …”
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Impairment of cocaine-mediated behaviours in mice by clinically relevant Ras-ERK inhibitors by Alessandro Papale, Ilaria Maria Morella, Marzia Tina Indrigo, Rick Eugene Bernardi, Livia Marrone, Francesca Marchisella, Andrea Brancale, Rainer Spanagel, Riccardo Brambilla, Stefania Fasano

“…However, to date, no clinically relevant inhibitor of this cascade has been tested in experimental models of addiction, a necessary step toward clinical trials. …”
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Cross-Talk between PPARγ and Insulin Signaling and Modulation of Insulin Sensitivity by Anna Leonardini, Luigi Laviola, Sebastio Perrini, Annalisa Natalicchio, Francesco Giorgino

“…Disturbances in the production of these factors may contribute to metabolic abnormalities, and PPARγ activation is also associated with beneficial effects on expression and secretion of a whole range of cytokines.…”
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Adaptive identification of critical nodes for fault‐on voltage support in islanded microgrids by Shiran Cao, Lipeng Zhu, Jiayong Li, Wen Huang, Lili He, Wei Zhang, Huimin Zhao, Zhikang Shuai

“…Abstract The shedding of critical distributed energy resources during faults in an islanded microgrid may induce widespread voltage drops, potentially triggering a cascade of reactions leading to the collapse of the entire system. …”
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Tearing-mediated Alfvénic Turbulence in a Relativistic Plasma by Stanislav Boldyrev, Nuno F. Loureiro

“…In astrophysical relativistic plasmas, Alfvénic turbulence exists across a wide range of scales. Similar to a nonrelativistic case, this turbulence can be influenced by the tearing instability. …”
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In vitro Release of Eosinophil Proteins in Allergic and Atopic Dermatitis Patients by L. K. Poulsen, C. M. Reimert, C. Bindslev-Jensen

“…To investigate whether eosinophils are stimulated in vivo or have acquired an increased susceptibility to stimuli from the coagulation cascade, the release of eosinophil proteins was compared for three groups of donors with different levels of serum IgE. (1) with atopic dermatitis (s-IgE > 5000 IU/ml, n = 11); (2) with inhalant allergy (200 < s-IgE < 2 000 IU/ml, n = 10); and (3) non-allergic (s- IgE < 100 IU/ml, n = 10). …”
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Facile colorimetric detection of As(V) in Rice with immobilized acid phosphatase on hollow metal-organic frameworks hybrid with peroxidase-like activity by Zhiyang Qin, Zhuolan Xu, Yixin Liu, Xinguang Qin, Gang Liu, Xinlin Wei, Haizhi Zhang

“…Then, based on the inhibition of As(V) on immobilized ACP and cascade reaction mediated by ACP and AuHT, a colorimetric biosensor was established with excellent simplicity. …”
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Procoagulant Phospholipids and Tissue Factor Activity in Cerebrospinal Fluid from Patients with Intracerebral Haemorrhage by Patrick Van Dreden, Guy Hue, Jean-François Dreyfus, Barry Woodhams, Marc Vasse

“…Brain contains large amounts of tissue factor, the major initiator of the coagulation cascade. Neuronal apoptosis after intracerebral haemorrhage (ICH) leads to the shedding of procoagulant phospholipids (PPLs). …”
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Signals of propaganda-Detecting and estimating political influences in information spread in social networks. by Alon Sela, Omer Neter, Václav Lohr, Petr Cihelka, Fan Wang, Moti Zwilling, John Phillip Sabou, Miloš Ulman

“…Together, they enable us to distinguish (p - value = 0.0001) between the two different classes of information cascades. In addition to constructing a bipartite graph connecting words and tweets to each cascade, we develop a quantitative measure and show how it can be used to distinguish between political and non-political discussions. …”
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Tumor microbiome: roles in tumor initiation, progression, and therapy by Shengxin Zhang, Jing Huang, Zedong Jiang, Huan Tong, Xuelei Ma, Yang Liu

“…We further propose the tumor microbiome may evade immunity and promote angiogenesis to support tumor progression, while uncovering specific microbial influences on each step of the metastatic cascade, such as invasion, circulation, and seeding in secondary sites. …”
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Drug Repositioning for Gynecologic Tumors: A New Therapeutic Strategy for Cancer by Kouji Banno, Miho Iida, Megumi Yanokura, Haruko Irie, Kenta Masuda, Yusuke Kobayashi, Eiichiro Tominaga, Daisuke Aoki

“…PGE2 is induced in the arachidonate cascade by COX-2. PGE2 maintains high expression of COX-2 and induces angiogenic factors including VEGF and bFGF, causing carcinogenesis. …”
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A Novel Role for Brain Natriuretic Peptide: Inhibition of IL-1β Secretion via Downregulation of NF-kB/Erk 1/2 and NALP3/ASC/Caspase-1 Activation in Human THP-1 Monocyte by Letizia Mezzasoma, Cinzia Antognelli, Vincenzo Nicola Talesa

“…Dysregulation of both IL-1β and its related pathways is involved in inflammatory/autoimmune disorders and in a wide range of other diseases. Identifying molecules modulating their expression is a crucial need to develop new therapeutic agents. …”
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Theoretical and Experimental Comparison Results of Dual-Channel 3D Quasi-Optical Network System between Frequency Selective Surface and Wire Grid Polarizer by Hai Wang, Xiaoming Liu, Junsheng Yu, Zejian Lu, Xiaodong Chen

“…The system structure based on the beam radius is traced by the complex beam parameter and system transfer matrix for deciding the positions of cascade mirrors. The design principles and test results of FSS with perforated hexagonal array and WGP printed on the dielectric substrate are discussed together. …”
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