QUALITY OF LIFE ASSESSMENT IN MULTIPLE MYELOMA PATIENTS UNDERGOING DOSE-REDUCED TANDEM AUTOLOGOUS STEM CELL TRANSPLANTATION by Alhossain A. Khalafallah, Kristina McDonnell, Hizb U. Dawar, Iain Robertson, David Woods

“…Our study showed that dose-reduced TASCT is well tolerated with low toxicity albeit the transient reduction in QOL during both transplants. …”
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Oleuropein in olive leaf, branch, and stem extracts: stability and biological activity in human cervical carcinoma and melanoma cells by Benčić Đani, Barbarić Monika, Mornar Ana, Klarić Daniela Amidžić, Brozovic Anamaria, Dabelić Sanja, Fadljević Mihaela, Marković Ana Karković

“…Apart from leaves, olive branches and stems make up a significant amount of olive waste. …”
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High infection rates and risk‐adapted prevention strategies in contemporary pediatric allogeneic hematopoietic stem cell transplantation by Tsz Wing Yeung, Wilson Yau Ki Chan, Sally Cheuk Ying Wong, Pamela Pui Wah Lee, Daniel Ka Leung Cheuk, Wing Leung

“…Abstract With recent changes in hematopoietic stem cell transplantation (HSCT) practices, such as the increasing use of alternative donors and ex vivo T‐cell depletion, how various risk factors interplay and affect the timeline of infections have not been well elucidated. …”
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Expression of innate immunity genes in human hematopoietic stem/progenitor cells – single cell RNA-seq analysis by Justyna Jarczak, Kannathasan Thetchinamoorthy, Diana Wierzbicka, Kamila Bujko, Mariusz Z. Ratajczak, Mariusz Z. Ratajczak, Magdalena Kucia

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QUALITY OF LIFE ASSESSMENT IN MULTIPLE MYELOMA PATIENTS UNDERGOING DOSE-REDUCED TANDEM AUTOLOGOUS STEM CELL TRANSPLANTATION by Iain Robertson, Hizb U. Dawar, Kristina McDonnell, Alhossain A. Khalafallah, David Woods

“…We conducted the European Organization of Research and Treatment of Cancer (EORTC) QLQ-C30 questionnaire via interviews at presentation, after each ASCT and thereafter every 3 months for 24 months. …”
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A pan-cancer study of ADAM9’s immunological function and prognostic value particularly in liver cancer by Mandana AmeliMojarad, Melika AmeliMojarad, Jiang Wang, Vahid Tavakolpour, Parvin Shariati

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Grainyhead-like 2 in development and cancer by Lijun Ma, Hongli Yan, Hui Zhao, Jianmin Sun

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Posttransplant Erythrocytosis after Allogenic Stem Cell Transplant for Acute Myeloid Leukemia: A Case Report and Review of Literature by Sherry S. Abraham, Saikumar Soman, Akshaya B. Ajish, Sreejith G. Nair

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Bioluminescence in cancer research - Applications and challenges by Shrikant B. Mali

“…BLI is also widely employed in cancer imaging, especially in light of recent advances in genetic engineering, stem cell, and gene therapy therapies. …”
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Tranexamic acid impairs plasmin generation on human mesenchymal stem cells and derived membrane microvesicles, halting pericellular proteolysis by Ramy Abou Rjeily, Christina Mrad, Fatiha Z. El-Ghazouani, Florence Toti, Audrey Cras, Audrey Cras, Eduardo Angles-Cano

“…IntroductionMesenchymal stem cells (MSCs) participate in the dynamic remodeling of the extracellular matrix during wound healing, natural bleeding processes or cancer progression. …”
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Uncoupling protein 2 and 4 expression pattern during stem cell differentiation provides new insight into their putative function. by Anne Rupprecht, Dana Sittner, Alina Smorodchenko, Karolina E Hilse, Justus Goyn, Rudolf Moldzio, Andrea E M Seiler, Anja U Bräuer, Elena E Pohl

“…UCP2's occurrence in cancer, immunological and stem cells indicates that UCP2 is present in cells with highly proliferative potential, which have a glycolytic type of metabolism as a common feature, whereas UCP4 is strongly associated with non-proliferative highly differentiated neuronal cells.…”
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Overexpression of Decorin Optimizes the Treatment Efficacy of Umbilical Cord Mesenchymal Stem Cells in Bleomycin-Induced Pulmonary Fibrosis in Rats by Yaofeng Zhi, Minghui Shu, Pinsheng Tang, Yingjie Li, Min Guo, Jiongrui Deng, Haixin Mo, Meimei Wu, Baoyi Liu, Yanyang Mai, Jie Ling, Xulin Zhao, Xin Zhang, Wanli Zuo

“…The death rate upon diagnosis is higher than that of many other cancer types. Mesenchymal stem cell (MSC) treatment of organ fibrosis is a hot topic in preclinical and clinical research because it effectively treats IPF. …”
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DNA barcoded peptide-MHC multimers to measure and monitor minor histocompatibility antigen-specific T cells after allogeneic stem cell transplantation by Sine R Hadrup, Marieke Griffioen, J H Frederik Falkenburg, Mirjam H M Heemskerk, Marian van de Meent, Michel G D Kester, Kyra J Fuchs, Marcus Göransson, Natasja W Ettienne, Rob C M de Jong, Eva A S Koster, Constantijn J M Halkes, Ferenc Scheeren, Peter van Balen

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Efficacy of palifermin in the treatment of oral mucositis in non-hematopoietic stem cell transplant pediatric patients: experience of a single tertiary hospital by Hasna Hamzi, Amal Binhassan, Amal Najmeldin, Ebtsam Alhariri, Bodour Elhussein, Nour Althibani, Ahmad Alenazi, Shahad Alsharif, Mohammad Alshahrani, Omar Alsharif, Nawaf Alkhayat, Yasser Elborai

“…Conclusion Palifermin is safe and well tolerated and shows some effect in non-hematopoietic stem cell transplant pediatric patients with severe oral mucositis post-intensified chemotherapy or radiation therapy.…”
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A novel human pluripotent stem cell gene activation system identifies IGFBP2 as a mediator in the production of haematopoietic progenitors in vitro by Paolo Petazzi, Telma Ventura, Francesca Paola Luongo, Heather McClafferty, Alisha May, Helen Alice Taylor, Michael J Shipston, Nicola Romanò, Lesley M Forrester, Pablo Menendez, Antonella Fidanza

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Protection of CD33-modified hematopoietic stem cell progeny from CD33-directed CAR T cells in rhesus macaques by Nicholas E. Petty, Stefan Radtke, Greta Kanestrom, Emily Fields, Olivier Humbert, Salvatore Fiorenza, Mallory J. Llewellyn, George S. Laszlo, Justin Thomas, Zach Burger, Kyle Swing, Haiying Zhu, Keith R. Jerome, Cameron J. Turtle, Roland B. Walter, Hans-Peter Kiem

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Expression of tripartite motif-containing protein 28 in primary breast carcinoma predicts metastasis and is involved in the stemness, chemoresistance, and tumor growth by Surekha Damineni, Sai A Balaji, Abhijith Shettar, Swetha Nayanala, Neeraj Kumar, Banavathy S Kruthika, Kalyanasundaram Subramanian, M Vijayakumar, Geetashree Mukherjee, Vaijayanti Gupta, Paturu Kondaiah

“…Furthermore, knockdown of tripartite motif-containing protein 28 resulted in the decrease of stemness as revealed by sphere formation assay as well as decreased expression of CD44 and Bmi1. …”
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Rehabilitation during intensive treatment of acute leukaemia including allogenic stem cell transplantation: a qualitative study of patient experiences by Lene Østergaard Jepsen, Lone Smidstrup Friis, Mette Terp Hoybye, Claus Werenberg Marcher, Dorte Gilså Hansen

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Global gene expression analysis of canine osteosarcoma stem cells reveals a novel role for COX-2 in tumour initiation. by Lisa Y Pang, Emma L Gatenby, Ayako Kamida, Bruce A Whitelaw, Ted R Hupp, David J Argyle

“…Both canine and human osteosarcoma has been shown to contain a sub-population of cancer stem cells (CSCs), which may drive tumour growth, recurrence and metastasis, suggesting that naturally occurring canine osteosarcoma could act as a preclinical model for the human disease. …”
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Chromosome-specific aberrations, rather than general aneuploidy, may drive mouse embryonic stem cell-derived teratoma metastasis by Joaquin Montilla-Rojo, Sanne Hillenius, Thomas F. Eleveld, Daniela C.F. Salvatori, Leendert H.J. Looijenga

“…Abstract Introduction Pluripotent stem cells (PSC) are known to recurrently acquire genetic aberrations including chromosomal aneuploidy during long-term culture of which the consequences remain largely unknown. …”
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