Differences in risk factors between all-cause and pulmonary embolism-related death in acute pulmonary embolism: insights from the COMMAND VTE registry-2 by Soichiro Kobayashi, Yoshito Ogihara, Yugo Yamashita, Takeshi Morimoto, Ryuki Chatani, Kazuhisa Kaneda, Yuji Nishimoto, Nobutaka Ikeda, Yohei Kobayashi, Satoshi Ikeda, Kitae Kim, Moriaki Inoko, Toru Takase, Shuhei Tsuji, Maki Oi, Takuma Takada, Kazunori Otsui, Jiro Sakamoto, Takeshi Inoue, Shunsuke Usami, Po-Min Chen, Kiyonori Togi, Norimichi Koitabashi, Seiichi Hiramori, Kosuke Doi, Hiroshi Mabuchi, Yoshiaki Tsuyuki, Koichiro Murata, Kensuke Takabayashi, Hisato Nakai, Daisuke Sueta, Wataru Shioyama, Tomohiro Dohke, Toru Sato, Ryusuke Nishikawa, Takeshi Kimura, Kaoru Dohi

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The value and application of a poorly differentiated cluster-based Ezrin marginal score system in the prognostic assessment of colorectal cancer by Yangyang Jiang, Ling Liu, Yingying Chang, Limei Gu, Yaohui Wang, Ting-Sheng Ling, Xiaolong Zhang

“…Abstract Aim This study aimed to explore the distribution of Ezrin-positive cells in poorly differentiated cluster (PDC) of colorectal cancer (CRC), and its correlation with both traditional and auxiliary pathological indicators, including E-cadherin and tumor-stroma ratio (TSR), as well as patient prognosis. …”
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Ecotoxicological health risk analysis of different fish species from the Black Sea coast of Türkiye by Evrim Sibel ÖNEL, Mustafa TÜRKMEN, Erkan KALIPCI

“…Furthermore, human health risk assessment from fish consumption was investigated using multiple statistical approaches, and a spatial distribution map of PTEs in the region was prepared. …”
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Immunoassayofantibodies to benzo[a]pyrene, estradiol and progesterone fordeterminationofpersonal lung cancer riskinmen by A. N. Glushkov, E. G. Polenok, S. A. Mun, L. A. Gordeeva, M. V. Kostyanko, Y. A. Magarill, V. A. Titov, N. E. Verzhbitskaya, I. A. Vafin

“…A personalized lung cancer risk assessment is important for disease prevention.The aim of the studywas to estimate a significance of immunoanalysis of antibodies to benzo[a]pyrene, estradiol and progesterone for lung cancer risk prediction in men with respect to age and smoking.Material and methods. …”
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Transformative insights from transcriptome analysis of colorectal cancer patient tissues: identification of four key prognostic genes by Nevin Belder, Sulgun Charyyeva, Edibe Ece Abaci Oruc, Hakiimu Kawalya, Namood-e Sahar, Nader Omidvar, Berna Savas, Arzu Ensari, Hilal Ozdag

“…In conclusion, our risk assessment model exhibits strong potential for predicting poor survival and unfavorable clinicopathological features in CRC patients, offering valuable insights for personalised management strategies.…”
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Targeted Metabolomic Serum Analysis of Patients with High and Low Risk of Endometrial Cancer Recurrence and Positive and Negative Lymph Node Status by Dagmara Pietkiewicz, Mikołaj Piotr Zaborowski, Szymon Plewa, Michał Potograbski, Cezary Miedziarek, Tomasz Kluz, Ewa Nowak-Markwitz, Jan Matysiak

“…Thus, targeted metabolomic serum profiling might be a powerful tool for improving risk assessment, enabling more personalized therapeutic approaches and management strategies in endometrial cancer.…”
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Association between the triglyceride-glucose index (TyG Index) and risk of colorectal cancer: a systematic review and meta-analysis by Hala Fathi EmamElkhir Omer, Mohamed Alghazali, Mohamed Y. Ibrahim, Nadeen Mohamed Yousif Abdalla, Ashraf Hassan Mohamed Hassan, Eram Asim Seidahmed Yousif, Aseel E. B. Abdhameed, Yaser Waheeb Slaiman Naser, Nawras Mustafa Elashai Hamad, Malaz A. I. Abdalla, Mohamed Osman Mohamed Idres, Ali Abdelhaleem Omar Ahmed, Yasir Ahmed Mohammed Elhadi, Sagad O.O. Mohamed

“…Abstract Background Colorectal cancer (CRC) is one of the most common malignancies worldwide, with increasing evidence linking metabolic dysregulation, such as insulin resistance and chronic inflammation, to its development and progression. …”
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Relationship of -31G/C (rs9904341) polymorphism in the survivin gene <i>BIRC5</i> and the risk of bladder cancer by E. E. Bashmakova, N. S. Panamarev, A. N. Kudryavtsev, D. V. Chernyaev, E. V. Slepov, R. A. Zukov, L. A. Frank

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Comparative analysis and optimization of tumor regression grade assessment systems in neoadjuvant therapy for esophageal squamous cell carcinoma by Qiao Yang, Xiaoqing Zhou, Jiayu Li, Jieyu Wang, Jingcheng Luo, Dan Luo, Lin Shi, Chengmin Zhou, Yi Wang, Xuefeng Leng, Qifeng Wang, Yang Liu, Yehan Zhou

“…Abstract Objective This study aims to compare and analyze the effectiveness of different tumor regression grade (TRG) assessment systems in evaluating neoadjuvant therapy for esophageal cancer, with the goal of identifying an optimal assessment method to guide clinical practice. …”
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CYP2D6-GENOTYPING IN THE ASSESSMENT OF THE EFFECTIVENESS OF THERAPY WITH TAMOXIFEN IN PATIENTS WITH ADVANCED HORMONE RECEPTOR-POSITIVE BREAST CANCER by L. N. Lyubchenko, M. G. Filippova, N. I. Mekhtieva, T. A. Shendrikova, A. V. Semaynikhina, A. V. Snegovoy

“…Pharmacogenetic testing of the CYP2D6 gene in patients with hormone-positive breast cancer can help to predict response to therapy and assess the risk of side effects with the aim of improving long-term treatment outcomes.…”
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Presence and Dermal Exposure to Benzene and Acetaldehyde in Hand Sanitizers Available in Taiwan by Chieh-An Cheng, Shih-Wei Tsai

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Methods for Preclinical Assessment of the Efficacy of Anticancer Medicines <i>in vivo</i> (Review) by M. L. Vasyutina, K. V. Lepik, M. S. Istomina, K. A. Levchuk, A. V. Petukhov, E. V. Shchelina, A. E. Ershova, O. N. Demidov, Ya. G. Toropova

“…INTRODUCTION. The main risk to the clinical translatability of preclinical results for anticancer medicinal products is posed by the difficulty of simulating clinical conditions in an experimental model. …”
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Diurnal Variation and Health Risk Assessment of Anthropogenic VOCs Concentrations in Abidjan, Côte d'Ivoire: a Comparative Study of Traffic and Domestic Fire Sites by Julien Bahino, Pamela Dominutti, Sékou Keita, Madina Doumbia, Marcellin Adon, Aurélie Colomb, Cathy Liousse, N’Datchoh Evelyne Touré, Agnès Borbon, Véronique Yoboue

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Association between GLP-1 receptor agonists as a class and colorectal cancer risk: a meta-analysis of retrospective cohort studies by Ying Zhong, Tingting Wu, Najeeb Ullah Khan

“…While these medications offer glycemic control and cardiovascular benefits, the risks have increased because of their potential impact on cancer risk, particularly colorectal cancer (CRC). …”
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Belatacept and non-melanoma skin cancer risk in kidney transplant recipients: a narrative review from a mechanistic and clinical perspective by Hany M. El Hennawy, Omar Safar, Ahmed Nassar, Mahmoud Z. El Madawie, Mohammad F. Zaitoun, Yasser M. Almahdi, Abdullah S. Al Faifi, Ibrahim Tawhari

“…Secondary objectives include evaluating the immunologic mechanisms underlying its distinct cancer risk profile, exploring combinatory regimens (particularly with mammalian target of rapamycin inhibitors), assessing metabolic and nephrotoxic implications, and addressing ethical and clinical considerations in switching stable patients from Calcineurin inhibitors to belatacept. …”
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Extracorporeal Detoxification Methods and Hemostasis System for Ovarian Cancer Patients. Clinical Case by A. S. Safonov, M. V. Zabelin, A. A. Izmailov, Z. A. Valiullina, A. R. Mukhametkulova, A. V. Vasilchenko, K. N. Zolotukhin

“…The clinical case was assessed in terms of P-selectin (CD62), which characterizes platelet activation processes. …”
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Evolution of the burden of disease for high BMI-associated colorectal cancer, 1990–2021: Global trends, regional heterogeneity, and population risk stratification by Guangyi zhu, Yilan Sun, Dongbo Lian, Buhe Amin, Guangzhong Xu, Jing Wang, Nengwei Zhang, Dezhong Wang

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Enhancing risk stratification in diabetic gastric cancer: muscle-fat ratio from photon-counting CT as a predictor of postoperative complications by Shuangxiang Lin, Yuchen Jin, Mengxi Xu, Shuyue Wang, Weisheng Yao, Jiaxing Wu, Xinhong Wang, Jianzhong Sun

“…We evaluated whether Photon-counting CT (PCD-CT) derived MFR predicts major postoperative complications, reflecting its value in perioperative risk stratification. Methods A retrospective analysis of 134 gastric cancer patients with type 2 diabetes was conducted. …”
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A predictive nomogram for assessing the likelihood of retrieving 12 lymph nodes after rectal cancer surgery: a single-center study by Jian Ma, Runyang Hao, Shuai Jiao, Qingmin Chen, Baohong Yang, Xu Guan, Jiale Li, Xinxuan Zhao, Yu Huo, Qingxia Xu, Haiyi Liu, Wen Su, Xishan Wang

“…ObjectiveThe retrieval of 12 lymph nodes (LNs) remains a crucial criterion for accurate staging and prognosis evaluation in rectal cancer (RC). However, some patients fail to meet this threshold after surgery. …”
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A scoping review and evidence map of radiofrequency field exposure and genotoxicity: assessing in vivo, in vitro, and epidemiological data by Steven G. Weller, Steven G. Weller, Julie E. McCredden, Victor Leach, Cordia Chu, Alfred King-yin Lam

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