Diversity and Novelty of Venom Peptides in Vermivorous Cone Snails, Subgenus <i>Rhizoconus</i> (Gastropoda: Mollusca) by Christine Marie C. Florece, Quentin Kaas, Neda Barghi, Arturo O. Lluisma

“…A large majority of cone snails (a species in the genus <i>Conus</i>) are vermivorous (worm-hunting), but the diversity and bioactivity of their venom peptides remain largely unexplored. …”
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Accumulation differences of high-value ingredients in different phenotype Lonicera macranthoides: insights from integrative metabolome and transcriptome analyses by Juan Zeng, Juan Zeng, Yu Qing Long, Yu Qing Long, Jia Yuan Zhu, Jia Yuan Zhu, Xue Sen Fu, Xue Sen Fu, Jing Yu Zhang, Jing Yu Zhang, Jia Wei He, Jia Wei He, Xiao Rong Liu, Xiao Rong Liu, Zhi Hui Wang, Zhi Hui Wang, Qiao Zhen Tong, Qiao Zhen Tong, Xiang Dan Liu, Xiang Dan Liu, Xiang Dan Liu, Ri Bao Zhou, Ri Bao Zhou, Ri Bao Zhou

“…While the specific accumulation pattern and the underlying molecular regulatory networks remain unclear. …”
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l-[5-11C]Glutamine PET imaging noninvasively tracks dynamic responses of glutaminolysis in non-alcoholic steatohepatitis by Yiding Zhang, Lin Xie, Masayuki Fujinaga, Yusuke Kurihara, Masanao Ogawa, Katsushi Kumata, Wakana Mori, Tomomi Kokufuta, Nobuki Nengaki, Hidekatsu Wakizaka, Rui Luo, Feng Wang, Kuan Hu, Ming-Rong Zhang

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Comparison of anti-biofilm and cytotoxic activity of Ag/AgO, Ag/Ag2O, and Ag/AgCl nanocomposites synthesized using stem, leaf, and fruit pericarp of Prunus mahaleb L by Zahra Dashtizadeh, Fereshteh Jookar Kashi

“…FT-IR confirmed the presence of functional groups involved in reduction and stabilization. XRD patterns validated the crystalline nature of the nanocomposites, with Ag/AgO displaying the smallest crystallite size. …”
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Microplastic and Extracellular Vesicle Interactions: Recent Studies on Human Health and Environment Risks by Eleonora Calzoni, Nicolò Montegiove, Alessio Cesaretti, Agnese Bertoldi, Gaia Cusumano, Giovanni Gigliotti, Carla Emiliani

“…The purpose of this review was to investigate how the relationships between MPs and EVs can affect cellular functions and how this interaction could impact environmental conditions leading to broader ecological risks. The interaction patterns and bioactivity of both MPs and EVs are strongly influenced by biophysical characteristics such as hydrophobicity, surface charge, and particle size, which have received particular attention from the scientific community. …”
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Pectiniferosides A–J: Diversified Glycosides of Polyhydroxy Steroids Isolated from the Sea Star <i>Patiria (=Asterina) pectinifera</i> by Ranran Zhang, Zhen Lu, Derui Wang, Zhi Yan, Xueting Sun, Xiaodong Li, Xiuli Yin, Song Wang, Ke Li

“…The discovery of saponins with multiple substitution patterns in sea stars exemplified the molecular diversity of secondary metabolites in marine echinoderms. …”
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Additive Manufacturing of Biopolymers for Tissue Engineering and Regenerative Medicine: An Overview, Potential Applications, Advancements, and Trends by Dhinakaran Veeman, M. Swapna Sai, P. Sureshkumar, T. Jagadeesha, L. Natrayan, M. Ravichandran, Wubishet Degife Mammo

“…Due to their biocompatibility, bioactiveness, and biodegradability, biopolymers such as collagen, alginate, silk fibroin, chitosan, alginate, cellulose, and starch are used in a variety of fields, including the food, biomedical, regeneration, agriculture, packaging, and pharmaceutical industries. …”
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Optogenetic Fine-Tuning of <i>Sus scrofa</i> Basic Fibroblast Growth Factor Expression in <i>Escherichia coli</i> by Fanqiang Meng, Zhimin Xu, Xia Fan, Zhisheng Wang, Libang Zhou

“…Moreover, various parameters of blue light illumination during fermentation were investigated, including initial cell density, light intensity, illumination duration, and pulsed illumination patterns. The results identified optimal conditions for maximizing bFGF yield in <i>E. coli</i>, specifically an initial OD₆₀₀ of 0.6, 800 lux blue light intensity, and 8 h total illumination in a 2 h on/off pattern. …”
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Eco-friendly innovation: Development of a multifunctional polyaniline-cuttlebone nanocomposite as a synergistic shield against doxorubicin-induced toxicity and a powerful antimicro... by Esraa Salama, Fatma I. Abo El-Ela, Walid Hamdy Hassan, Ahmed A. Farghali, Abdullah A. Eweis, Sarah H.M. Hafez, Rehab Mahmoud

“…Notably, the PANI/CB composite exhibited a distinct crystallite size and characteristic XRD pattern, along with a significant BET surface area, demonstrating strong antimicrobial properties. …”
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Identification of α-Glucosidase Inhibitors and Assessment of Human Safety from 491 Native Plant Species of Jeju Island by Ho-Min Kang, Jin-Kyu Kang, Pomjoo Lee, Chang-Gu Hyun

“…This study examined the bioactivities of 570 plant extracts sourced from Jeju Island to evaluate their potential as cosmetic raw materials. …”
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Restoration of antibiotic associated diarrhea induced gut microbiota disorder by using Dictyophora indusiata water-insoluble polysaccharides in C57BL/6J mice by Yong Lai, Yong Lai, Qifan Zhang, Maohan Xu, Xiurong Guo, Quan Zhou, Qiuyu Liu, Huiling Deng, Can Song

“…Macrofungal polysaccharides are rich in bioactivities and have attracted much attention for their good performance in anti-inflammatory, antioxidant, anti-obesity and anti-tumor properties. …”
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Prognostic relevance and performance characteristics of serum IGFBP‐2 and PAPP‐A in women with breast cancer: a long‐term Danish cohort study by Ulrick Espelund, Andrew G. Renehan, Søren Cold, Claus Oxvig, Lee Lancashire, Zhenqiang Su, Allan Flyvbjerg, Jan Frystyk

“…We measured IGF‐I, IGF‐II, pro‐IGF‐II, IGF bioactivity, IGFBP‐2, ‐3, and pregnancy‐associated plasma protein A (PAPP‐A), an IGFBP regulator, in baseline samples of 301 women with breast cancer treated on four protocols (Odense, Denmark: 1993–1998). …”
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Metarhizium spp. encode an ochratoxin cluster and a high efficiency ochratoxin-degrading amidohydrolase revealed by genomic analysis by Gang Wang, Wenqing Wu, Nancy P. Keller, Xu Guo, Erfeng Li, Junning Ma, Fuguo Xing

“…Conclusion: These findings reveal different patterns of OT synthesis in fungi and provide a potential OTA degrading enzyme for industrial applications.…”
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Investigation of the anti-cancer drugs imatinib and thalidomide using analytical spectroscopy (FT-IR, UV-Vis) and molecular docking simulations by P. Venkata Ramana, Y. Rama Krishna, Prasadarao Bobbili, K. Venkata Prasad, K. Chandra Mouli

“…The UV-Vis spectra of the medications were examined in order to comprehend the bioactivity of the molecule and the charge transfer between its outermost orbitals. …”
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GIS-Based Remote Sensing Image Information Analysis of the South Atlantic Ecological Environment and Diversity of Deep-Sea Microorganism with Antifungal Effects by Jingjing Xu, Peisheng Yan

“…Meanwhile, the unique environment of the ocean has endowed the marine microorganism with affluent diversity, which can display a variety of bioactivities. In this study, thirty-two seawater and sediment samples were collected from different depths within the scope of 5 m to 3203 m at 18 sampling sites in the South Atlantic Ocean. 1017 culturable strains were obtained after isolation and identification. …”
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Effects of sandblasting and acid etching on the surface properties of additively manufactured and machined titanium and their consequences for osteoblast adhesion under different s... by Osman Akbas, Amit Gaikwad, Amit Gaikwad, Leif Reck, Nina Ehlert, Nina Ehlert, Anne Jahn, Jörg Hermsdorf, Andreas Winkel, Andreas Winkel, Meike Stiesch, Meike Stiesch, Andreas Greuling

“…Acid etching introduced characteristic irregular patterns on the surface with only marginal consequences for the resulting overall roughness. …”
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Gomphrenin-Based Decarboxylated and Acylated Pigments from Basella alba L. Fruit Extracts Impair Survival of Colorectal Cancer Cells but Not Normal Cells – In Vitro Study by Katarzyna Sutor-Świeży, Łukasz Kozioł, Mateusz Knap, Ewa Dziedzic, Monika Bieniasz, Przemysław Mielczarek, Monika Baj-Krzyworzeka, Rafał Szatanek, Sylwia Bobis-Wozowicz, Łukasz Popenda, Sławomir Wybraniec, Malgorzata Tyszka-Czochara

“…Hence, decarboxylated derivatives with potential health-promoting properties were generated by controlled thermal modifications of gomphrenin structure. Bioactivity experiments were performed on gomphrenin acylated (malabarin and globosin) and decarboxylated derivatives (17-decarboxy-gomphrenin, 2-decarboxy-gomphrenin, and 2,17-bidecarboxy-gomphrenin) derived from the fruit extracts using preparative HPLC. …”
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Chemical Composition and Biological Activities of <i>Lagopsis supina</i> Extract: Antioxidant, Adipogenic, and Ani-Inflammatory Effects by Juhyun Choi, Duc Dat Le, Nayoung Roh, Jiseok Lee, Deumaya Shrestha, Thientam Dinh, Vinhquang Truong, Badamtsetseg Bazarragchaa, Soo-Yong Kim, Sung-Suk Suh, Mina Lee, Jong Bae Seo

“…Chemical profiling revealed eight major compound groups: glycosides, organic acids, terpenoids, flavonoids, phenylglycosides, phenolics, fatty acids, and others characterized by their mass fragmentation patterns, precursors, and UV absorption spectra. In silico analysis confirmed these compounds’ bioactivities, demonstrating strong interactions and binding affinities with antioxidant, adipogenic, and anti-inflammatory protein targets. …”
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Playing Around the Coumarin Core in the Discovery of Multimodal Compounds Directed at Alzheimer’s-Related Targets: A Recent Literature Overview by Mariagrazia Rullo, Gabriella La Spada, Angela Stefanachi, Eleonora Macchia, Leonardo Pisani, Francesco Leonetti

“…To enhance the clarity of presentation, synthetic coumarin-based MTDLs are categorized into four clusters based on their substitution pattern and reported bioactivities: (i) mono-, (ii) di-, and (iii) polysubstituted coumarins directed at protein targets, and (iv) coumarins directed at protein targets with additional metal-chelating features. …”
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Phenotypic expression of ADAMTS13 in glomerular endothelial cells. by Ramesh Tati, Ann-Charlotte Kristoffersson, Anne-Lie Ståhl, Matthias Mörgelin, David Motto, Simon Satchell, Peter Mathieson, Minola Manea-Hedström, Diana Karpman

“…The aim of this study was to examine ADAMTS13 expression in kidneys from ADAMTS13 wild-type (Adamts13⁺/⁺) and deficient (Adamts13⁻/⁻) mice and to investigate the expression pattern and bioactivity in human glomerular endothelial cells.…”
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