From waste to functionality: Gastrointestinal stability and bioactivity of phenolic compounds in apple peel biofortified by wounding and UVA radiation by Esteban Villamil-Galindo, Edwin E. Reza-Zaldivar, Marilena Antunes-Ricardo, Andrea Marcela Piagentini, Daniel A. Jacobo-Velázquez

“…These findings demonstrate the feasibility of using combined abiotic stresses as a sustainable and cost-effective strategy to valorise apple by-products, providing bioactive-rich ingredients with potential applications in functional foods and nutraceuticals.…”
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Spray-drying microencapsulation of fixed oils: An innovative and sustainable technology to enhance oxidative stability, functionality and application in food systems by Kutloano Mangope, Tafadzwa Kaseke, Olaniyi A. Fawole

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Functional and Nutritional Characterization of a Natural Diet Based on BIO102 Iron Biofortified Beans in Newly Weaned Mice by N. Jiménez‐Cardozo, Magda C. Díaz‐Vesga, Sonia Gallego‐Castillo, Daniel Álvarez, Juan Camilo Orozco‐Agredo, José Guillermo Ortega, Camilo Morales‐Jiménez

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Preventive Gastroprotective Effect of a Functional Food Based on Quinoa (<i>Chenopodium quinoa</i> Willd.) and Quercetin in a Murine Model of Ibuprofen-Induced Gastric Damage by Maribel Valenzuela-González, José Luis Cárdenas-López, Armando Burgos-Hernández, Norma Julieta Salazar-López, Manuel Viuda-Martos, Mónica A. Villegas-Ochoa, Gustavo Martínez-Coronilla, J. Abraham Domínguez-Avila, Shela Gorinstein, Gustavo A. González-Aguilar, Rosario Maribel Robles-Sánchez

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Utilization of pH-driven methods to fortify nanoemulsions with multiple polyphenols by Hualu Zhou, Bingjing Zheng, David Julian McClements

“…In general, the pH-driven method provides researchers with a versatile approach of incorporating multiple polyphenols with different characteristics into functional food and beverages using a simple and inexpensive method.…”
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Antioxidant/Anti-Inflammatory Potential and Sensory Acceptance of Granola Bars Developed with Sorghum Sprout Flour Irradiated with UV-A LED Light by Alan A. Ruiz-Hernández, Ofelia Rouzaud-Sández, Maribel Valenzuela-González, J. Abraham Domínguez-Avila, Gustavo A. González-Aguilar, Maribel Robles-Sánchez

“…Overweight and obesity are worldwide problems; several strategies have been applied to counteract them, including the development of functional foods with specific bioactivities. Sorghum has been shown in in vitro and in vivo studies to improve various biomarkers related to overweight, obesity, and inflammation, particularly when sprouted and irradiated with UV light. …”
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Effects of foliar applications of zinc on fruit biofortification and quality traits of greenhouse mini plum tomato cultivars by Claudio Cannata, Li Mei, Rosario Paolo Mauro, Guglielmo Fichera, Giacomo Pepe, Giovanna Aquino, Leo Sabatino, Lorena Vultaggio, Cherubino Leonardi

“…Compared to control, Zn application did not affect yield but increased total Zn concentration (+66 %) while reducing Zn bioaccessibility (−26 %), leading to a lower increase in bioaccessible Zn (+23 %). …”
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The protective effect of Gentiana lutea flower against mycotoxin toxicity in a gastrointestinal barrier in vitro model by Giacomo Di Matteo, Giacomo Di Matteo, Giacomo Di Matteo, Massimo Frangiamone, Pilar Vila-Donat, Valter Di Cecco, Luciano Di Martino, Lara Manyes, Luisa Mannina, Luisa Mannina, Luisa Mannina

“…The digested Gentiana samples reduced the expression of pro-apoptotic genes (BAX, CASP3), preserved intestinal barrier integrity by modulating tight junction-related genes (CL-2, ZO-1), and promoted antioxidant responses through SRXN1 regulation.ConclusionThese findings highlight the potential of Gentiana lutea flowers as a source of functional phytocompounds for intestinal barrier protection against mycotoxins.…”
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In Vitro Neuroprotective Effects of a Mixed Extract of Bilberry, <i>Centella asiatica</i>, <i>Hericium erinaceus</i>, and Palmitoylethanolamide by Rebecca Galla, Sara Ferrari, Ivana Miletto, Simone Mulè, Francesca Uberti

“…These findings suggest that this nutraceutical combination may support the cellular pathways involved in neuronal resilience and healthy brain ageing, offering potential as a functional food ingredient or dietary supplement.…”
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Nanoencapsulated roselle anthocyanins extract extends lifespan in Western diet-fed male Drosophila via enhanced mitochondrial biogenesis by Qianhua Yuan, Wanhan Song, Ya Wang, Yutong Xie, Dazhang Deng, Nageena Qayyum, Huawen Li, Honghui Guo

“…Body weight, triglycerides (TG) levels, lifespan, locomotor function, intestinal integrity, oxidative stress markers, mitochondrial function, and related pathways were assessed. …”
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Effects of Peanut Processing on Masticatory Performance during Variable Appetitive States by Fiona McKiernan, Richard D. Mattes

“…These observations may have implications for bioaccessibility of energy and cardioprotective nutrients as well as endocrine responses, following peanut consumption.…”
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Lactic Acid Bacteria and Yeast Fermentation to Improve the Nutritional Value of <i>Ulva rigida</i> by Marta Brandão, Diogo J. Marques, Sofia Sousa, Marília Mateus, Helena M. Pinheiro, M. Manuela R. da Fonseca, Carla Pires, Maria Leonor Nunes, António Marques, M. Teresa Cesário

“…The protein bioaccessibility in the fermented products was 11- to 12-fold higher than that of the raw alga. …”
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Optimization of Pectin-Zein Beads via Response Surface Methodology for Enhanced Colon-Targeted Delivery of <i>p</i>-Coumaric Acid from Rice Husk Extract by Ilaria Frosi, Raffaella Colombo, Chiara Milanese, Adele Papetti

“…The generally very low bioaccessibility of polyphenols can be enhanced through several different strategies, especially when these metabolites are components of extracts used as food ingredients. …”
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Impact of the Food Matrix on the Antioxidant and Hypoglycemic Effects of Betalains from Red Prickly Pear Juice After In Vitro Digestion by Roman-Maldonado Yvonne, Villanueva-Rodríguez Socorro Josefina, Mojica Luis Alfonso, Urías-Silvas Judith Esmeralda

“…The results showed that complex matrices (FJ, BF, and BP) enhanced betalain bioaccessibility, with FJ exhibiting the highest bioaccessibility (59%). …”
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Changes in the Profile of Phenolic Compounds and in the Antioxidant, Hypoglycemic, and Antidiabetic Activities of a Beverage Based on Sesame By-Product Caused by the Simulated Gast... by Jonhatan Carrasco-Chávez, María Fernanda Quintero-Soto, Rosalio Velarde-Barraza, Ignacio Alfredo Rivero-Espejel, Ismael Díaz-Peña, Martha Elena Vázquez-Ontiveros, Ramona Julieta Espinoza-Moreno, Luz Adriana Ontiveros-García, Jesús Mateo Amillano-Cisneros, Janitzio Xiomara K. Perales-Sánchez, Oscar Daniel Argüelles-López, Fernando Salas-López, Jennifer Vianey Félix-Medina

“…The results of this study not only improve the understanding of the impact of gastrointestinal digestion on the bioaccessibility of phenolic compounds but also suggest potential applications in formulating functional foods with enhanced antioxidant, hypoglycemic, and antidiabetic properties, contributing to the development of health-promoting food products.…”
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Food-Grade Pickering Emulsions Stabilized by Ultrasound-Treated Foxtail Millet Prolamin: Characterization and <i>In Vitro</i> Release Behavior of Curcumin by Yu Guo, Yuewei Luo, Zhiyuan Ren, Xinpeng Zhang, Huiling Duan, Zhizong Liu, Xiaowen Wang

“…Moreover, MIPEs with Cur increased the bioaccessibility of Cur. This study provides new insights into a novel delivery system designed with FMP-U for encapsulating hydrophobic compounds, thereby enhancing their stability, sustained release, and bioaccessibility.…”
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Antioxidant and ACE-Inhibition Activities After In Vitro Digestion of a Non-Fermented Dairy Beverage Enriched with Postbiotics of <i>Lactobacillus</i> spp. by Norma Angélica Bolivar-Jacobo, Raúl Alberto Reyes-Villagrana, Martha María Arévalos-Sánchez, Ana Luisa Rentería-Monterrubio, Eduardo Santellano-Estrada, Nora Aidee Salas-Salazar, América Chávez-Martínez

“…Such findings highlight the potential of postbiotics as functional ingredients to enhance the antioxidant and ACE-inhibition activities of non-fermented dairy beverages, further adding to their appeal as health-promoting dairy food.…”
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COMPARATIVE VALUATION OF HEPATOPROTECTIVE ACTIVITY OF FLAVONOIDS IN COURSE ALCOHOLIZATION OF RATS by E. O. Sergeeva, E. G. Dorkina, L. A. Sadzhaya, I. V. Skulte, O. M. Sharenko, I. M. Derevenets

“…In the experiments on white outbreed female rats hepatoprotective action of medical and preventive application of diosmin and flavicin in comparison with quercetine by the capacity of biological indices of functional liver state normalization on the model of course alcoholization. …”
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Caffeic Acid-Modified Mushroom Chitosan as a Natural Emulsifier for Soybean Oil-Based Emulsions and Its Application in β-Carotene Delivery by Jiaofen Lin, Jian Zeng, Guozong Shi, Zesheng Zhuo, Yanyun Guan, Zhipeng Li, Hui Ni, Peng Fei, Bingqing Huang

“…In this study, we developed a soybean oil-based emulsion system stabilized by caffeic acid-modified mushroom-derived chitosan, significantly enhancing its functional properties. The modification increased the grafting ratio from 5.02% to 8.26%, which greatly improved antioxidant activity and antimicrobial efficacy against Escherichia coli and Staphylococcus aureus. …”
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Study on Effect of Germination on Flavonoid Content and Nutritional Value of Different Varieties of Chickpeas by Jiyuan Xue, Jia Yang, Yongqi Yin

“…These results provided critical insights for optimizing the nutritional and functional properties of chickpeas via sprouting and established a scientific basis for the development of functional foods from germinated chickpeas, underscoring their potential to support dietary health and wellness.…”
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