Association between echocardiographic parameters of cardiac structure and function and mild cognitive impairment by Kai Zhang, Xiaoxia Liu, Siyu Huang, Xinrui Liu, Meiqi Zhao, Chao Xue, Shijun Xia, Jianzeng Dong, Yu Kong, Changsheng Ma

“…The links between cardiac structure and function and MCI are not well understood. We aimed to explore the association between echocardiographic parameters of cardiac structure and function and MCI in CVD patients. …”
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Ghrelin’s Effects on Proinflammatory Cytokine Mediated Apoptosis and Their Impact on β-Cell Functionality by Antonia Diaz-Ganete, Gloria Baena-Nieto, Isabel M. Lomas-Romero, Jose Francisco Lopez-Acosta, Irene Cozar-Castellano, Francisco Medina, Carmen Segundo, Alfonso M. Lechuga-Sancho

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The Potential Mechanism and the Role of Antioxidants in Mitigating Oxidative Stress in Alzheimer’s Disease by Rayees Ahmad Naik, Mehak Naseer Mir, Ishfaq Ahmad Malik, Rima Bhardwaj, Fahad M Alshabrmi, Mahmoud Abdulrahman Mahmoud, Majid Alhomrani, Abdulhakeem S. Alamri, Walaa F. Alsanie, Ahmed Hjazi, Tanmoy Ghatak, Burkhard Poeggeler, Mahendra P Singh, Gopenath TS, Sandeep Kumar Singh

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Modelling Peroxisomal Disorders in Zebrafish by Chenxing S. Jiang, Michael Schrader

“…The drive to understand the role of peroxisomes in human health and disease, as well as their functions in tissues and organs or during development, has led to the establishment of vertebrate models. …”
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Impact of Varicocele on The Expression of Testicular Enzymes Involved in The Transsulfuration Pathway by Azam Shiasi, Marziyeh Tavalaee, Ramesh Monajemi, Dattilo M, Mohammad Hossein Nasr-Esfahani

“…We evaluated sperm parameters and functional tests,as well as the expression of CBS, CSE, and HO-1 proteins using Western blot analysis. …”
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Mindfulness-Based Intervention Effects on EEG and Executive Functions: A Systematic Review by Gilberto Galindo-Aldana, Luis Arturo Montoya-Rivera, Jose Jaime Esqueda-Elizondo, Everardo Inzunza-Gonzalez, Enrique Efren Garcia-Guerrero, Alfredo Padilla-Lopez, Tara G. Bautista, Cynthia Torres-González

“…</b> The qualitative results show that the research on the effects of MBI on behavior and cognitive skills, including executive function, social cognition, and EEG analysis, is very scarce but consistent in suggesting strong correlations on cognitive and electrophysiological alpha–beta proportions asymmetry on frontal areas. …”
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Microbial Community Characteristics and Underlying Drivers Along the Streams, Tributaries, and Main Stems of the Yangtze River Source Region by Futing Liu, Luyao Kang, Lele Lin, Sisi Yu

“…Based on 16S amplicon sequencing, spectral and physicochemical analyses, we examined the microbial communities as well as their influencing factors along the stream orders. …”
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Cyanidin-3-<i>O</i>-Glucoside Mitigates Amyloid-Beta (1–42)-Induced Apoptosis in SH-SY5Y Cells by Regulating Ca²⁺ Homeostasis and Inhibiting Mitochondrial Dysfunction by Chao Ma, Yu Nie, Donglei Zhang, Lulu Ran, Su Xu, Xun Ran, Junya Huang, Lingshuai Meng

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Systematic network pharmacology and experimental validation reveal anti-glioma mechanisms of ganoderma lucidum via multi-target regulation by Xue Mei, Jufen Zhang, Lu Chen, Fang Wang

“…Ganoderma lucidum (Lingzhi), a well-known medicinal fungus, has shown anti-tumor effects in several malignancies, but its molecular mechanisms in glioma remain largely unclear. …”
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The effect of the administration form of antibiotic therapy on the gut microbiome in patients with infected diabetic foot ulcers - DFIATIM trial by Chahrazed Mekadim, Jakub Mrazek, Kateřina Olša Fliegerová, Hana Sechovcová, Tiziana Maria Mahayri, Radka Jarošíková, Jitka Husáková, Veronika Wosková, Petr Tůma, Jan Polák, Dominika Sojáková, Andrea Němcová, Michal Dubský, Vladimíra Fejfarová

“…Conclusion The present study reported alterations in gut microbiota composition and functionality and provided the bacterial markers as well as potential metabolic signatures associated with each administration mode in patients with iDFUs, which may be used as a reference set for future studies of the effect of antibiotics administration on the gut microbiome of patients with iDFUs. …”
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Docosahexaenoic acid-acylated astaxanthin monoester enhances microglial autophagy for ameliorating amyloid-β load and cognitive deficits in models of Alzheimer’s disease by Xiaoxu Wang, Bo Dong, Yu Song, Zhigao Wang, Yuming Wang, Jie Xu, Changhu Xue

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Functional activity and peripheral insulin resistance in patients with different types of onset of diabetes mellitus by Tatiana Vasil'evna Nikonova, Elena Vladimirovna Pekareva, Ivan Ivanovich Dedov

“…The most significant decrease in beta-cell functional activity was found in patients with type 1 diabetes mellitus (HOMA-F 8.9%).Onset of LADA (Latent autoimmune diabetes in adults) and type 2 diabetes mellitus (T2DM) was also characterized by decreasein beta-cell functional activity (HOMA-F 39.2% and 63.9%, respectively), as well as by development of IR: HOMA-IR 3.7 and 7.2,respectively. …”
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Pharmaceutical therapy of Q-wave acute myocardial infarction: effects on adrenal morphology and function by Yu. V. Rogovskaya, Yu. M. Paderov, A. N. Repin, A. A. Sidelnikov

“…Adequate analgetic and thrombolytic therapy, as well as beta-adrenoblocker treatment, prevented adrenal medulla depletion. …”
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Physical activity modifies associations between cerebrospinal fluid tau measures and executive function by Ryan J. Dougherty, Anja Soldan, Corinne Pettigrew, Barry Greenberg, Adam P. Spira, Abhay Moghekar, Marilyn Albert

“…Physical activity moderates the impact of tau pathology on executive function but shows no significant effect on amyloid‐beta pathology. …”
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A phase 1 clinical trial of the sigma‐2 receptor complex allosteric antagonist CT1812, a novel therapeutic candidate for Alzheimer's disease by Michael Grundman, Roger Morgan, Jason D. Lickliter, Lon S. Schneider, Steven DeKosky, Nicholas J. Izzo, Robert Guttendorf, Michelle Higgin, Julie Pribyl, Kelsie Mozzoni, Hank Safferstein, Susan M. Catalano

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Role of Defective Interfering Particles in Complement-Mediated Lysis of Parainfluenza Virus-Infected Cells by Jenna R. Aquino, Candace R. Fox, Griffith D. Parks

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Gut microbiota regulates exercise-induced hormetic modulation of cognitive functionResearch in context by Elisa Cintado, Pablo Muela, Lucía Martín-Rodríguez, Ignacio Alcaide, Patricia Tezanos, Klara Vlckova, Benjamín Valderrama, Thomaz F.S. Bastiaanssen, María Rodríguez-Muñoz, María L. de Ceballos, María R. Aburto, John F. Cryan, José Luis Trejo

“…Interpretation: These findings suggest that the hormetic effects of physical exercise on cognitive function and neurogenesis are mediated by corresponding changes in the gut microbiota, highlighting a novel mechanistic link between exercise, brain function, and gut microbiota composition. …”
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RNA-sequencing demonstrates transcriptional differences between human vocal fold fibroblasts and myofibroblasts by Michelle Bretl, Lingxin Cheng, Christina Kendziorski, Susan L. Thibeault

“…Enrichment analyses revealed pathways related to cell signaling, receptor-ligand activity, and regulation of cell functions in scarred fibroblasts, pathways related to cell adhesion in normal fibroblasts, and pathways related to ECM binding in fibroblasts treated with TGF-β1. …”
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The power spectrum and functional connectivity characteristics of resting-state EEG in patients with generalized anxiety disorder by Hangwei Wang, Shaoqi Mou, Xuedan Pei, Xiaomei Zhang, Shanhong Shen, Jianfeng Zhang, Xinhua Shen, Zhongxia Shen

“…The results revealed significantly increased beta-band activity; decreased ipsilateral fronto-temporal and parieto-temporal functional connectivities in the lower frequency bands (theta–beta band); as well as decreased frontal‒parietal and frontal‒occipital connectivities in the higher frequency bands (beta‒gamma band) in GAD patients. …”
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Periosteal pressure sensitivity of the chest bone as a measure for autonomic function in ischemic heart disease by Nanna Ørsted, Søren Ballegaard, Jesper Kristiansen, Finn Gyntelberg, Ake Hjalmarson, Jens Faber, Jens Faber

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