The Role of Inflammation in Diabetes: Current Concepts and Future Perspectives by Sotirios Tsalamandris, Alexios S Antonopoulos, Evangelos Oikonomou, George-Aggelos Papamikroulis, Georgia Vogiatzi, Spyridon Papaioannou, Spyros Deftereos, Dimitris Tousoulis

“…The role of obesity, adipose tissue, gut microbiota and pancreatic beta cell function in diabetes are under intensive scrutiny with several clinical trials to have been completed while more are in development. …”
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Biochemical characterization and activity profiling of recombinant phospholipase A2 from Hemiscorpius lepturus expressed in E. coli with in vivo antibody response by Moslem Najafi, Delavar Shahbazzadeh, Parichehreh Yaghmaie, Hasan Mirzahoseini

“…Abstract The structure and function of phospholipase A2 (PLA2) in scorpion venom are relatively unexplored, making further study crucial. …”
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Triangular Fuzzy Finite Element Solution for Drought Flow of Horizontal Unconfined Aquifers by Christos Tzimopoulos, Nikiforos Samarinas, Kyriakos Papadopoulos, Christos Evangelides

“…The initial water table is assumed to be curvilinear, following the form of an inverse incomplete beta function. To account for uncertainties in the system, the hydraulic parameters—hydraulic conductivity (K) and porosity (S)—are treated as fuzzy variables, considering sources of imprecision such as measurement errors and human-induced uncertainties. …”
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Stem cell-based therapeutic strategies for down syndrome and Alzheimer’s disease by Osama Hamadelseed, Thomas Skutella

“…Abstract Background Down syndrome (DS) and Alzheimer’s disease (AD) are two distinct yet interconnected neurological conditions that share overlapping pathological features, including amyloid-beta plaque accumulation, neuroinflammation, and progressive neurodegeneration. …”
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Rosuvastatin effects on the HDL proteome in hyperlipidemic patients by Vavlukis Ana, Mladenovska Kristina, Davalieva Katarina, Vavlukis Marija, Dimovski Aleksandar

“…The advancements in proteomics have provided a better understanding of the functionality of apolipoproteins and lipoprotein-associated proteins, with the HDL lipoprotein fraction being the most studied. …”
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A Case of Systemic Lupus Erythematosus in a Patient Presenting with Libman-Sacks Endocarditis by Mariann Al-Jehani, Faisal Al-Husayni, Ahmed Almaqati, Jomanah Shahbaz, Saad Albugami, Wail Alameen

“…The patient was started on diuretics, anticoagulants, angiotensin inhibitors, beta-blockers, and hydroxychloroquine. He underwent successful mechanical mitral valve replacement with a 27 mm St. …”
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Unraveling salivary microbiota diversity following kidney transplantation: insights from baseline peripheral blood lymphocyte subsets by Xuyu Xiang, Tianyin Wang, Peng Ding, Yi Zhu, Ke Cheng, Yingzi Ming

“…It is therefore hypothesized that the salivary microbiota may be linked to immune function.Materials and Methods We analyzed 108 saliva samples from 37 KT patients using 16S rRNA sequencing. …”
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Analysis of the Endocrine Responses to Anti-Diabetes Drugs: An Issue of Elevated Plasma Renin Concentration in Sodium-Glucose Co-Transporter 2 Inhibitor by Lin CW, Hung SY, Chen IW

“…Participants taking sulfonylurea (55.8 vs 26.34 ng/L, P=0.043), dipeptidyl peptidase-4 inhibitor (DPP4i) (47.14 vs 32.26 ng/L, P=0.096), or sodium-glucose co-transporter 2 inhibitor (SGLT2i) (64.58 vs 28.11 ng/L, P=0.117) had higher plasma renin concentrations compared to those without this drug but the aldosterone levels did not differ, as well as for other adrenal tests and thyroid function. …”
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Various endurance training intensities improve GFR and Up-regulate AQP2/GSK3β in lithium-induced nephropathic rats by Shadan Saberi, Mohammad Amin Rajizadeh, Mohammad Khaksari, Azadeh Saber, Mohammad Akhbari, Soheil Aminizadeh, Forouzan Rafie

“…Exercise has been shown to have protective effects on renal function, yet the impact of varying exercise intensities on lithium-induced nephropathy is not well understood. …”
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DEVELOPMENT OF AN AUTOMATED FLUORESCENCE MICROSCOPY ASSAY FOR QUANTIFYING FACTORS AFFECTING RED BLOOD CELL (RBC) SICKLING IN SICKLE CELL DISEASE (SCD) by ML Arrojo, ACS Pinto, SK Haddad, RA Panepucci

“…Sickle cell disease is the most common monogenetic disease in the world, characterized by a point mutation in the sixth codon of the beta-globin gene, which generates mutant hemoglobin S (HbS). …”
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Effectiveness of a selective If channel inhibitor ivabradine in patients with stable angina by E. V. Kuleshova

“…To study clinical effectiveness of ivabradine (7,5 mg twice a day) as a part of combined therapy, and its effects on physical stress (PS) tolerability in patients with Functional Class (FC) II-III stable angina and absolute or relative contraindications to beta-adrenoblockers (BAB).Material and methods. …”
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Syntheses, Characterization, and Antibacterial Evaluation of P. grandiflora Extracts Conjugated with Gold Nanoparticles by A. Murei, K. Pillay, A. Samie

“…We determined the antimicrobial activity of the conjugates using well diffusion and the microdilution assays. Results. …”
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Cardiopulmonary responses to acute exogenous ketosis at rest, and during submaximal and maximal exercise by Christopher D. Crabtree, Justen Stoner, Alex Buga, Bradley Robinson, Drew Decker, Ashwini Chebbi, Xavier El‐Shazly, Emily Murphy, Aydan Jordan, Teryn Bedell, Madison L. Kackley, Tyler McClure, Yuchi Han, Orlando P. Simonetti, Jeff S. Volek

“…Abstract Nutritional ketosis achieved through various methods in animals and humans has been shown to augment cardiac efficiency and function. However, this response during exercise has not been well characterized. …”
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The GLP-1 receptor agonist liraglutide inhibits necroptosis and neuroinflammation in a mouse model of Parkinson’s disease with diabetes co-morbidity by Xiaomin Zhang, Pengyang Du, Bo Bai, Peng Feng, Xia Lian, Christian Hölscher, Yongqing Wang, Guofang Xue

“…After that, body weight and blood glucose of each group mice were measured, and the open field experiment and gait analysis experiment were performed to detect the motor and non-motor symptoms of mice, western blotting and immunohistochemistry experiments were performed to test the levels of necroptosis-related proteins tumor necrosis factor-α (TNF-α), receptor interacting serine/threonine kinase 1 (RIP1) and neuroinflammation-related proteins nuclear factor kappa-B p-p65 (NF-κB p-p65), nuclear factor kappa-B p65 (NF-κB p65), interleukin-1 beta (IL-1β), and monocyte chemoattractant protein-1 (MCP-1).ResultsThe GLP-1 receptor agonist liraglutide inhibited necroptosis and neuroinflammation via TNF-α signaling in diabetic PD mice, decreasing blood glucose and improving motor function and mood. …”
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Sex-specific changes in energy demand during the preplaque stage in a transgenic Alzheimer’s mouse model by Rongwan Sun, Leonie-Kim Zimbalski, Stefanie Schreyer, David Baidoe-Ansah, Aida Harutyunyan, Arnd Heuser, Rachel N. Lippert, Joachim Spranger, Knut Mai, Sebastian Brachs

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Effects of Different Individuals and Verbal Tones on Neural Networks in the Brain of Children with Cerebral Palsy by Ryosuke Yamauchi, Hiroki Ito, Ken Kitai, Kohei Okuyama, Osamu Katayama, Kiichiro Morita, Shin Murata, Takayuki Kodama

“…The results were further analyzed using Independent Component Analysis frequency analysis with exact Low-Resolution Brain Electromagnetic Tomography, allowing for the identification and visualization of neural activity in three-dimensional brain functional networks. <b>Results</b>: The results of the ICA frequency analysis for each participant revealed distinct patterns of brain activity in response to verbal encouragement from the mother and PT, with differences observed across the theta, alpha, and beta frequency bands. …”
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Active RIS-NOMA Uplink in URLLC, Jamming Mitigation via Surrogate and Deep Learning by Ghazal Asemian, Mohammadreza Amini, Burak Kantarci

“…The paper utilizes the surrogate optimization technique, particularly the Radial Basis Function (RBF), to address the non-convex optimization problem minimizing the power consumption. …”
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Yoda1 Inhibits TGFβ-Induced Cardiac Fibroblast Activation via a BRD4-Dependent Pathway by Perwez Alam, Sara M. Stiens, Hunter J. Bowles, Hieu Bui, Douglas K. Bowles

“…Transforming growth factor-beta (TGFβ) is a well-established regulator of fibroblast activation; however, the precise molecular mechanisms, particularly the involvement of ion channels, remain poorly understood. …”
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Effects of Tannin Supplementation in Diet on the Resistance to Ammonia Stress of Pacific White Shrimp Litopenaeus vannamei by Xiuhong Zhang, Han Gong, Ping Chen, Jiajia Wang, Zhao Chen, Zhiqiang Chang, Jitao Li

“…The integration of DEGs and DMs indicates that dietary tannins highly alter the digestion and absorption functions of proteins, as well as the biosynthesis and metabolism of amino acids. …”
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Infant low-frequency EEG cortical power, cortical tracking and phase-amplitude coupling predicts language a year later. by Adam Attaheri, Áine Ní Choisdealbha, Sinead Rocha, Perrine Brusini, Giovanni M Di Liberto, Natasha Mead, Helen Olawole-Scott, Panagiotis Boutris, Samuel Gibbon, Isabel Williams, Christina Grey, Maria Alfaro E Oliveira, Carmel Brough, Sheila Flanagan, Usha Goswami

“…This phenomenon has been measured in both children and adults, reflecting speech understanding by adults as well as cognitive functions such as attention and prediction. …”
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