Nightmares without atonia as an early symptom of diffuse Lewy bodies disease by Paulo Roberto de Brito-Marques, Roberto Vieira de Mello, Luciano Montenegro

“…Immunohistochemical staining for anti-tau, anti-beta-amyloid, and anti-prion protein were negative. …”
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The effect of beetroot extract with silver nano particles on rumen parameters in Awassi lambs by Tamara Natiq Dawood

“…AgNPs-BR improved rumen function by altering its pH, ammonia, and VFAs concentration, as well as the total bacteria and protozoa count. …”
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S100A9 knockout decreases the memory impairment and neuropathology in crossbreed mice of Tg2576 and S100A9 knockout mice model. by Hee Jin Kim, Keun-A Chang, Tae-Young Ha, Jeonga Kim, Sungji Ha, Ki-Young Shin, Cheil Moon, Wolfgang Nacken, Hye-Sun Kim, Yoo-Hun Suh

“…We observed that S100A9KO/Tg2576 (KO/Tg) mice displayed an increased spatial reference memory in the Morris water maze task and Y-maze task as well as decreased amyloid beta peptide (Aβ) neuropathology because of reduced levels of Aβ, C-terminal fragments of amyloid precursor protein (APP-CT) and phosphorylated tau and increased expression of anti-inflammatory IL-10 and also decreased expression of inflammatory IL-6 and tumor neurosis factor (TNF)-α when compared with age-matched S100A9WT/Tg2576 (WT/Tg) mice. …”
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Use of metered dose inhalers for bronchodilator responsiveness testing: laboratory practices in Australia and opportunities for carbon footprint reduction by Michael J Loftus, Karin Leder, Belinda R Miller, Jayne Roberts, Nicholas Romeo, Pam Matsas, Brigitte Borg

“…We aimed to determine the practices around MDI use and disposal within Australia’s major lung function testing laboratories and identify the actions that most influence the carbon footprint of bronchodilator responsiveness (BDR) testing.Methods Australia’s 45 accredited lung function laboratories were invited to participate in an online survey asking about their volume of BDR testing, as well as practices around MDI use such as the number of actuations per BDR test, reuse of MDIs between patients and disposal method. …”
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Erratum to: Two-loop renormalization group restrictions on the standard model and the fourth chiral family by Yu. F. Pirogov, O. V. Zenin

“…Abstract This erratum includes correction of misprints in the expressions for $$\beta $$ β functions, as well as remarks clarifying the notation. …”
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Nuclear receptor CAR represses TNFalpha-induced cell death by interacting with the anti-apoptotic GADD45B. by Yukio Yamamoto, Rick Moore, Richard A Flavell, Binfeng Lu, Masahiko Negishi

“…<h4>Methodology/principal findings</h4>PB activation of nuclear xenobiotic receptor CAR is found to induce the Gadd45b gene in mouse liver throughout the development of HCC as well as in liver tumors. Given the known function of GADD45B as a factor that represses Mitogen-activated protein Kinase Kinase 7 - c-Jun N-terminal Kinase (MKK7-JNK) pathway-mediated apoptosis, we have now demonstrated that CAR interacts with GADD45B to repress Tumor Necrosis Factor alpha ( TNFalpha)-induced JNK1 phosphorylation as well as cell death. …”
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Constructing a research model for liver regeneration by using hepatocyte-like organoid derived from human pluripotent stem cells by WANG Chenxi, YANG Shuchun, JIA Yuyan, HUANG Yue

“…Results Morphology evidence as well as expres-sion of marker genes showed that hPSCs-derived HLO was able to initiate a post-injury regeneration response after APAP treatment. …”
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Preliminary associations between brain metabolites and oral microbiome profiles during adolescence by Brittney D. Browning, Anna E. Kirkland, Maria I. Perica, Melinda A. Engevik, Alexander V. Alekseyenko, Lindsay M. Squeglia

“…While gut microbiome-brain connections are well studied, the relationship between the oral microbiome and brain function remains underexplored, despite growing evidence of its relevance to human health-particularly during this developmental period. …”
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Decreased mitochondrial‐related gene expression in adipose tissue after acute sprint exercise in humans: A pilot study by Mona Esbjörnsson, Håkan C. Rundqvist, Barbara Norman, Ted Österlund, Eric Rullman, Jens Bülow, Eva Jansson

“…Differential gene expression analysis indicated a decrease in signaling for mitochondrial‐related pathways, including oxidative phosphorylation, electron transport, ATP synthesis, and heat production by uncoupling proteins, as well as mitochondrial fatty acid beta oxidation. …”
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Do microglia metabolize fructose in Alzheimer’s disease? by Annalise M. Sturno, James E. Hassell Jr., Miguel A. Lanaspa, Kimberley D. Bruce

“…Microglia, the brain resident macrophages, have the potential to be novel therapeutic targets as they regulate many facets of AD, including lipid droplet (LD) accumulation, amyloid beta (Aβ) clearance, and neuroinflammation. To carry out such functions, microglia undergo phenotypic changes, which are linked to shifts in metabolism and substrate utilization. …”
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Application of polish experience in the implementation of the flood directive in Georgia – hydrological calculations by Diana Egiazarova, Marina Kordzakhia, Andrzej Wałęga, Edyta Drożdżal, Marta Milczarek, Anna Radecka

“…A rainfall hyetogram was found using the beta distribution function. Effective rainfall was calculated by the SCS-CN method. …”
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CARDIORENAL INTERACTION IN DECOMPENSATED CHRONIC HEART FAILURE by Zh. D. Kobalava, S. V. Villevalde, M. A. Efremovtseva

“…Patients with these variants of AKI as compared to patients without AKI had more pronounced hydration, as well as less frequent prescription of loop diuretics and beta-blockers during outpatient treatment.Conclusion. …”
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TREATMENT OF PATIENTS WITH ESSENTIAL HYPERTENSION 1-2 GRADE WITH METOPROLOL TARTRATE AND ANALYSIS OF HEART RATE VARIABILITY by V. E. Oleinikov, V. A. Budanova, A. V. Kulyutsin

“…Long-term therapy with Egilok retard provides improvement of life quality and significant cardioprotective effect. Beta-blocker therapy can be optimized by consideration of HRV patient type.…”
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Therapeutic potential of cedrol in alleviating cognitive impairments in aluminum chloride-induced Alzheimer's disease: A biomarker-based approach by Mohd Sajad, Rafat Ali, Rajesh Kumar, Nida Jamil Khan, Shadma Wahab, Saad Ali Alshehri, Sonu Chand Thakur

“…The study also assessed its impact on inflammatory enzymes such as lipoxygenase (LOX), tumor necrosis factor alpha (TNF-α), and cyclooxygenase-2 (COX-2), as well as additional enzymes, including glycogen synthase kinase-3 beta (GSK-3β), Rho-associated protein kinase II (ROCK II), and Na+/K+ ATPase. …”
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Targeting GJB4 to inhibit tumor growth and induce ferroptosis in pancreatic cancer by Xiangru Zheng, Wenjun Li, Xiaoli Li, Qianyi Yao, Luquan Zheng, Rongrong Fan, Ping Bie

“…The role of gap junction protein beta 4 (GJB4) in PC has been scarcely reported. Therefore, the aim of this study was to investigate the function of GJB4 in PC cells and its potential as a therapeutic target.MethodsThe expression of GJB4 in patients with PC was examined using data from The Cancer Genome Atlas (TCGA), The Human Protein Atlas, Gene Expression Omnibus (GEO), Tumor Immune Estimation Resource (TIMER), microRNA Target Prediction Database (miRDB), and Encyclopedia of RNA Interactomes (ENCORI). …”
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Sjögren’s syndrome is associated with a reduction in the surface area of the right caudal anterior cingulate gyrus by Ping Wang, Yunpeng Tai, Xiaofang Zhu, Xinyi Wan, An Sun, Jiajia Wang, Hui Cheng, Jingwei Hong, Yi Zhang, Xiaobing Wang

“…Neurological involvement in SS represents one of the more severe and challenging aspects, with complications affecting the central system leading to cognitive dysfunction, sensory neuropathy, and multifocal sensorimotor neuropathies among other cortical function abnormalities. The relationship between cerebral cortex structure and neurological pathologies is well-documented, yet the impact of SS on cerebral cortex structure remains unclear. …”
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On Extended d-D Kappa Distribution by Arak M. Mathai, Hans J. Haubold

“…The aim of the present paper is to bring to attention the application of various forms of the kappa distribution, its various special cases and its generalizations, which, in scalar-variable and multivariate situations, belong to a general family of distributions known as Mathai’s pathway models, comprising three different families of functions, namely the generalized type-1 beta, type-2 beta and gamma families. …”
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Ameliorative and Renoprotective Effect of Electrical Stimulation on Blood Sugar, Blood Urea Nitrogen (BUN), Creatinine Levels, and the Islets of Langerhans Weight in Diabetic Mice by Suhariningsih Suhariningsih, S. Glory, F. Khaleyla, H. N. Kusumawati, M. Septriana, Y. Susilo, A. K. Yaqubi, S. D. Astuti, A. Syahrom

“…Diabetes mellitus (DM) is a chronic metabolic disease or disorder characterized by high blood sugar levels as well as impaired carbohydrate, lipid, and protein metabolism due to insulin function insufficiency. …”
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Cardiovascular Diseases and Non-Alcoholic Fatty Liver Disease: Relationship and Pathogenetic Aspects of Pharmacotherapy by A. V. Nelidova, M. A. Livzan, N. A. Nikolaev, T. S. Krolevets

“…Despite the large number of works on this topic, we do not have a clear opinion on the impact on cardiovascular risk, interaction and the contribution of various factors, as well as algorithms for managing patients with non-alcoholic fatty liver disease to reduce the risk of cardiovascular diseases. …”
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Effects of Vitamin D Supplementation on Glucose and Insulin Homeostasis and Incident Diabetes among Nondiabetic Adults: A Meta-Analysis of Randomized Controlled Trials by Huilin Tang, Deming Li, Yufeng Li, Xi Zhang, Yiqing Song, Xinli Li

“…We found no significant effects of vitamin D supplementation on insulin secretion or beta cell function indexes. Based on the data from six trials involving 39,633 participants and 2533 incident T2D cases, vitamin D supplementation was not associated with the risk of incident diabetes compared to placebo (pooled relative risk: 1.01, 95% confidence interval: 0.93 to 1.08). …”
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