Carcinoid Syndrome-Induced Ventricular Tachycardia by Austin B. Rupp, Abdulmohsin Ahmadjee, Jack H. Morshedzadeh, Ravi Ranjan

“…Previous case reports have described carcinoid syndrome associated with coronary vasospasm and the well-characterized carcinoid heart disease. Case. …”
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Cognitive performance, mental health, and quality of life in β-thalassemia individuals: a comprehensive analysis by Khaled Elbeh, Muhamad R. Abdel Hameed, Romany H. Gabra, Alya O. Mohamed, Gellan k. Ahmed

“…Regular monitoring and appropriate interventions are crucial for optimizing their overall well-being and functioning.…”
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EFFICACY AND SAFETY OF ALBAREL IN PATIENTS WITH MILD, MODERATE AND SEVERE HYPERTENSION by N. N. Borovkov, K. V. Mazalov, D. I. Abelevich, O. E. Vilkova, T. A. Staroverova, A. A. Vostokova, S. V. Vyalova, E. V. Sovetskaya

“…The aim of the study was to evaluate the efficacy and safety (influence on carbohydrate, lipid and mineral metabolism, as well as nitrogen-excreting function of kidneys) of monotherapy with rilmenidine in patients with mild to moderate AH, as well as treatment of patients with severe AH as multiple combined treatment. 43 patients with essential AH I-HI degree, aged 22 to 79, were enrolled in this open label study after signing an informed consent form. …”
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Pathogenetic therapeutic approaches for endocrine diseases based on antisense oligonucleotides and RNA-interference by Olga Golounina, Ildar Minniakhmetov, Ramil Salakhov, Rita Khusainova, Ekaterina Zakharova, Igor Bychkov, Natalia Mokrysheva

“…In this review we focus on diseases of the endocrine system and discuss potential RNA-targeted therapeutic opportunities in diabetes mellitus, including monogenic beta cell diabetes, and obesity, including syndrome obesity and monogenic obesity, as well as in non-monogenic or complex endocrine disorders. …”
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Prebiotic supplementation in patients with type 1 diabetes: study protocol for a randomised controlled trial in Canada by Shyamchand Mayengbam, Raylene A Reimer, Sonia Butalia, Carol Huang, Elizabeth Rosolowsky, Munier A Nour, Josephine Ho, Weilan Wang, Shannon Pyke, Heidi Virtanen

“…Importantly, the prebiotic group maintained their serum C peptide level (marker of residual beta cell function) while the placebo group saw a drop. …”
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A survey on hygienic and physicochemical properties of Istrian cheese by Andrea Skelin, Dubravka Samaržija, Sulejman Redžepović, Samir Kalit, Mirna Mrkonjić Fuka, Višnja Magdić, Jasmina Havranek

“…However, the number of bacterial indicators rapidly declined during the ripening and they were under the detection limit for “ready to consume” cheese and therefore indicated their good bacteriological quality. Regression function of the effects of the ripening time on physicochemical properties of Istrian cheese during ripening showed a substantial increase in total solids, in salt, in moisture and in salt content as well as in the lactic acid in the total solids. …”
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Sleep Fragmentation Modulates the Neurophysiological Correlates of Cognitive Fatigue by Oumaïma Benkirane, Peter Simor, Olivier Mairesse, Philippe Peigneux

“…In the low cognitive load/undisturbed sleep (LCL/UdS) condition, low beta activity increased, suggesting a relaxed focus, as well as mid beta activity associated with active thinking. …”
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Comparative Analysis of Pioglitazone and Tirzepatide on Body Weight, Glucose Levels, Neuroinflammation, and Oxidative Stress in Diabetic Rats by Alhowail A, Aldawsari MF, Aldubayan M

“…The survival percentage, body weight, behavioral assessments (Y-maze, novel object recognition (NOR)), glucose concentrations, inflammatory mediators tumor necrosis factor alpha (TNF-α), interleukin 6 (IL-6), and interleukin-1 beta (IL-1β), as well as oxidative stress biomarkers superoxide dismutase (SOD), glutathione peroxidase (GPx), malondialdehyde (MDA), and lipid peroxidation were evaluated following the conclusion of the treatments.Results: The results demonstrate that diabetes decreased survival rates, body weight, cognitive function, increased glucose levels, neuroinflammation, and oxidative stress. …”
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The Reliability of Diagnosing Schizophrenia Using the GRU Layer in Conjunction with EEG Rhythms by Pankaj Kumar Sahu, Karan Jain

“…In our investigation of RDCGRU deep learning architectures, we noticed that Con-1-D layers connected special learning networks function well with the α-EEG rhythm for the EEG rhythm-based verification of schizophrenia. …”
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Geometric and topological characterization of the cytoarchitecture of islets of Langerhans. by Manu Aggarwal, Deborah A Striegel, Manami Hara, Vipul Periwal

“…Insulin and glucagon, secreted by beta and alpha cells, respectively, are responsible for metabolic switching between fat and glucose utilization. …”
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Longitudinal characterization reveals behavioral impairments in aged APP knock in mouse models by Lisa Blackmer-Raynolds, Lyndsey D. Lipson, Isabel Fraccaroli, Ian N. Krout, Jianjun Chang, Timothy Robert Sampson

“…Therefore, we performed an in-depth longitudinal study over 16 months, assessing cognition in these two strains, as well as assessments of motor function. While no cognitive deficits are observed in either genotype throughout the first year of life, 16-month-old APPSAA, but not APPWT mice show initial signs of spatial memory decline. …”
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Rationalisation of the differences between APOBEC3G structures from crystallography and NMR studies by molecular dynamics simulations. by Flavia Autore, Julien R C Bergeron, Michael H Malim, Franca Fraternali, Hendrik Huthoff

“…Recently, three NMR and two crystal structures of the catalytic deaminase domain of A3G have been reported, but these are in disagreement over the conformation of a terminal beta-strand, beta2, as well as the identification of a putative DNA binding site. …”
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Population pharmacokinetics and exposure–response analyses of safety (ARIA‐E and isolated ARIA‐H) of lecanemab in subjects with early Alzheimer's disease by Oneeb Majid, Youfang Cao, Brian A. Willis, Seiichi Hayato, Osamu Takenaka, Bojan Lalovic, Sree Harsha Sreerama Reddy, Natasha Penner, Larisa Reyderman, Sanae Yasuda, Ziad Hussein

“…Abstract Lecanemab (Leqembi®) was recently approved by health authorities in the United States, Japan, and China to treat early Alzheimer's disease (AD), including patients with mild cognitive impairment (MCI) or mild dementia due to Alzheimer's disease upon confirmation of amyloid beta pathology. Extensively and sparsely sampled PK profiles from 1619 AD subjects and 21,929 serum lecanemab observations from two phase I, one phase II, and one phase III studies were well characterized using a two‐compartment model with first‐order elimination. …”
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The octopamine receptor Octβ2R regulates ovulation in Drosophila melanogaster. by Junghwa Lim, Paul R Sabandal, Ana Fernandez, John Martin Sabandal, Hyun-Gwan Lee, Peter Evans, Kyung-An Han

“…All three known beta adrenergic-like octopamine receptors stimulate cAMP production in vitro. …”
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Canada goose fecal microbiota correlate with geography more than host‐associated factors by Joshua C. Gil, Heather R. Skeen, Celeste Cuellar, Sarah M. Hird

“…However, there were significant differences in microbial alpha diversity based on state of origin as well as significant positive correlations between geography and beta diversity. …”
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Prevention of atrial fibrillation episodes in patients with chronic heart failure: a new approach to the old problem by Yu. M. Pozdnyakov, O. N. Miller, S. A. Luchinsky, V. L. Doshchitsyn

“…The treatment of the leading pathology resulted in achieving target blood pressure levels (in 67,3 % of the patients), as well as in reducing functional class of angina (70 %) and CHF (94,5 %). …”
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Health Literacy and Behaviors of Patients and Caregivers Related to Glycemic Control Among Individuals With Type 2 Diabetes in Chiang Mai Province, Thailand by Chaimongkon S, Sakulwattana W, Ong-Artborirak P, Liyanage E, Seangpraw K

“…Linear regression analysis showed that, after adjusting for sex, age, education level, financial status, duration of diabetes, smoking, and alcohol consumption, FBS was significantly associated with patients’ HL (Beta = − 0.161), SCB (Beta = − 0.197), caregivers’ HL (Beta = − 0.217), and caregivers’ patient care behaviors (Beta = − 0.181). …”
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Intracoronary epinephrine and verapamil in the refractory no-reflow phenomenon in patients with acute myocardial infarction by S. V. Dil, E. V. Vyshlov, V. V. Ryabov

“…This will ensure better preservation of left ventricular systolic function, as well as improve the prognosis and clinical course of the disease.…”
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Role of vitamin D deficiency in type 2 diabetes mellitus and diabetic neuropathy development by Anna P. Stepanova, Tatiana L. Karonova, Anna A. Bystrova, Vadim B. Bregovsky

“…It is reported that vitamin D deficiency can contribute to insulin resistance development, and change in vitamin D receptor activity or extra- and intracellular calcium concentration due to vitamin D deficiency can affect pancreatic β-cells function and lead to decrease in insulin production. …”
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Bacterial response to the 2021 Orange County, California, oil spill was episodic but subtle relative to natural fluctuations by Melissa L. Brock, Joana F. Tavares-Reager, Jialin Dong, Alyse A. Larkin, Toan Lam, Nataly Pineda, Christopher I. Olivares, Katherine R. M. Mackey, Adam C. Martiny

“…Similarly, changes in function were related to anomalous declines in photosynthetic pathways and anomalous increases in sulfur metabolism pathways as well as aromatic degradation pathways. …”
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