Dimerization-dependent serine protease activity of FAM111A prevents replication fork stalling at topoisomerase 1 cleavage complexes by Sowmiya Palani, Yuka Machida, Julia R. Alvey, Vandana Mishra, Allison L. Welter, Gaofeng Cui, Benoît Bragantini , Maria Victoria Botuyan, Anh T. Q. Cong, Georges Mer, Matthew J. Schellenberg, Yuichi J. Machida

“…Missense mutations in the catalytic domain cause hyper-autocleavage and are associated with genetic disorders with developmental defects. Despite the enzyme’s biological significance, the molecular architecture of the FAM111A serine protease domain (SPD) is unknown. …”
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Sustainable Ultrasound-Assisted Solid-Phase peptide synthesis (SUS-SPPS): Less Waste, more efficiency by Salvatore Mottola, Alessandra Del Bene, Vincenzo Mazzarella, Roberto Cutolo, Ida Boccino, Francesco Merlino, Sandro Cosconati, Salvatore Di Maro, Anna Messere

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Consenso Brasileiro de Lipedema pela metodologia Delphi by Alexandre Campos Moraes Amato, Ana Paula Rolim Maia Peclat, Rodrigo Kikuchi, Antonio Carlos de Souza, Mariana Thalyta Bertolin Silva, Roney Hans Prager de Oliveira, Daniel Augusto Benitti, Julio Cesar Peclat de Oliveira

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Antimalarial Combination Therapies Increase Gastric Ulcers Through an Imbalance of Basic Antioxidative‑Oxidative Enzymes in Male Wistar Rats. by Kalange, Muhamudu, Nansunga, Miriam, Keneth Iceland, Kasozi, Kasolo, Josephine, Namulema, Jackline, Kasande Atusiimirwe, Jovile, Tiyo Ayikobua, Emanuel, Ssempijja, Fred, Munanura, Edson Ireeta, Matama, Kevin, Semuyaba, Ibrahim, Zirintunda, Gerald Gerald, Okpanachi, Alfred Omachonu

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Safety of Drinking Water from Primary Water Sources and Implications for the General Public in Uganda by Keneth Iceland, Kasozi, Sarah, Namubiru, Roland, Kamugisha, Ejike, Daniel Eze, Fred, Ssempijja, Alfred, Omachonu Okpanachi, Hellen, Wambui Kinyi, Jovile Kasande, Atusiimirwe, Dickson Stuart, Tayebwa, Joy, Suubo, Edgar Mario, Fernandez, Nathan, Nshakira, Andrew, Tamale

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In vitro Antibacterial Efficacy of Bidens pilosa, Ageratum conyzoides and Ocimum suave Extracts against HIV/AIDS Patients’ Oral Bacteria in South-Western Uganda by Joseph Obiezu, Chukwujekwu Ezeonwumelu, Muhammad, Ntale, Steve, Okwudili Ogbonnia, Ezera, Agwu, Julius, Kihdze Tanayen, Keneth Iceland, Kasozi, Okonkwo, Chukwudi Onyeka, Anthonia, Shodunke, Ambrose, Amamchukwu Akunne, Onokiojare, Ephraim Dafiewhare, Jennifer, Chibuogwu Ebosie, Frederick, Byarugaba

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Correction to: Antimalarial Combination Therapies Increase Gastric Ulcers Through an Imbalance of Basic Antioxidative‑Oxidative Enzymes in Male Wistar Rats. by Kalange, Muhamudu, Nansunga, Miriam, Keneth Iceland, Kasozi, Kasolo, Josephine, Namulema, Jackline, Atusiimirwe, Jovial Kasande, Emmanuel Tiyo Ayikobua, Emmanuel Tiyo, Ssempijja, Fred, Munanura, Edson Ireeta, Matama, Kevin, Semuyaba, Ibrahim, Zirintunda, Gerald, Okpanachi, Alfred O.

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Protocol of an open-label safety and feasibility pilot study of ketamine-assisted psychotherapy for methamphetamine use disorder (the KAPPA trial) by Jonathan Brett, Celia Morgan, Nadine Ezard, Brendan Clifford, Krista J Siefried, Robert May, Liam Acheson, Kathryn Fletcher, Harriet MacDonald, Gillinder Bedi, Alexandre Guerin, Elizabeth Knock, Michael Millard, Jess Doumany

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ABO-incompatible liver transplantation – exploring utilitarian solutions to restricted access and organ shortages: A single-centre experience from Johannesburg, South Africa by E U Wessels, J Loveland, H Maher, P Gaylard, B Bobat, A D Mahomed, D Parbhoo, M R Beretta, C Hajinicolaou, P Walabh, S Berkenfeld, D Demopoulos, S Rambarran, B Ströbele, F van der Schyff, J Fabian, L Brannigan

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Genome data based deep learning identified new genes predicting pharmacological treatment response of attention deficit hyperactivity disorder by Yilu Zhao, Zhao Fu, Eric J. Barnett, Ning Wang, Kangfuxi Zhang, Xuping Gao, Xiangyu Zheng, Junbin Tian, Hui Zhang, XueTong Ding, Shaoxian Li, Shuyu Li, Qingjiu Cao, Suhua Chang, Yufeng Wang, Stephen V. Faraone, Li Yang

“…The current study employed a comprehensive approach, combining genome-wide association analyses (GWAS) and deep learning (DL) methods, to elucidate the genetic underpinnings of pharmacological treatment response in ADHD. …”
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Low concentrations of Lactobacillus rhamnosus GG ( Yoba®) are safe in male Drosophila melanogaster by Keneth Iceland, Kasozi, Aisha, Bukenya, Ejike, Daniel Eze, Josephine, Kasolo, Dickson Stuart, Tayebwa, Fred, Ssempijja, Joy, Suubo, Andrew, Tamale, Isaac, Echoru, Ibrahim, Ntulume, Sarah, Kemuma Onkoba, Lisa Nkatha, Micheni, Emmanuel Tiyo, Ayikobua, Oscar Hilary, Asiimwe, Muhamudu, Kalange

“…Yoba consumed at 1% was associated with greater physiological benefits in Drosophila melanogaster. Findings in the study offer a rationale for the consumption of Yoba ® at 1% in humans as is currently being promoted by the Yoba for Life consortium, however, high concentrations of Yoba ® would disrupt physiological function as shown by this study.…”
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Low concentrations of Lactobacillus rhamnosus GG ( Yoba®) are safe in male Drosophila melanogaster by Keneth Iceland, Kasozi, Aisha, Bukenya, Ejike, Daniel Eze, Josephine, Kasolo, Dickson Stuart, Tayebwa, Fred, Ssempijja, Joy, Suubo, Andrew, Tamale, Isaac, Echoru, Ibrahim, Ntulume, Sarah Kemuma, Onkoba, Lisa Nkatha, Micheni, Emmanuel Tiyo, Ayikobua, Oscar Hilary, Asiimwe, Muhamudu, Kalange

“…Yoba consumed at 1% was associated with greater physiological benefits in Drosophila melanogaster. Findings in the study offer a rationale for the consumption of Yoba ® at 1% in humans as is currently being promoted by the Yoba for Life consortium, however, high concentrations of Yoba ® would disrupt physiological function as shown by this study.…”
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Trial protocol of an open-label pilot study of oral naltrexone–bupropion combination pharmacotherapy for the treatment of methamphetamine use disorder (the NABU trial) by Jonathan Brett, Paul S Haber, Nicholas Lintzeris, Didier Jutras-Aswad, Nadine Ezard, Brendan Clifford, Krista J Siefried, Adrian John Dunlop, Liam Acheson, Carl Moller, Michael Christmass, Kirsten Morley, Steven Shoptaw, Madhukar H Trivedi

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Biological Properties, Bioactive Constituents, and Pharmacokinetics of Some Capsicum spp. and Capsaicinoids by Gaber, El-Saber Batiha, Ali, Alqahtani, Oluwafemi, Adeleke Ojo, Hazem M., Shaheen, Lamiaa, Wasef, Mahmoud, Elzeiny, Mahmoud, Ismail, Mahmoud, Shalaby, Toshihiro, Murata, Adrian, Zaragoza-Bastida, Nallely, Rivero-Perez, Amany, Magdy Beshbishy, Keneth, Iceland Kasozi, Philippe, Jeandet, and Helal F., Hetta

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Wits Transplant Unit Annual Report 2022: Adult and paediatric liver transplantation by E U Wessels, K Kinandu, M Beretta, S Berkenfeld, B Bobat, L Brannigan, R Britz, D Demopoulos, L Doedens, P Gaylard, H Maher, A Mahomed, V Mudau, D Parbhoo, S Rambarran, M Reynders, F van der Schyff, B Ströbele, J Fabian, J Loveland

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Misconceptions on COVID-19 Risk Among Ugandan Men: Results From a Rapid Exploratory Survey, April 2020 by Keneth Iceland, Kasozi, MacLeod, Ewan, Ssempijja, Fred, Mahero, Michael W., Matama, Kevin, Musoke, Grace Henry, Bardosh, Kevin, Ssebuufu, Robinson, Wakoko-Studstil, Florence, Echoru, Isaac, Tiyo Ayikobua, Emmanuel, Mujinya, Regan, Nambuya, Grace, Onohuean, Hope, Zirintunda, Gerald, Ekou, Justine, Welburn, Susan Christina

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Community Drivers Affecting Adherence to WHO Guidelines Against COVID-19 Amongst Rural Ugandan Market Vendors. by Usman, Ibe Michael, Ssempijja, Fred, Ssebuufu, Robinson, Lemuel, Ann Monima, Archibong, Victor Bassey, Ayikobua, Emmanuel Tiyo, Aruwa, Joshua Ojodale, Kembabazi, Stellamaris, Kegoye, Eric Simidi, Ayuba, John Tabakwot, Okeniran, Olatayo Segun, Echoru, Isaac, Adeoye, Azeez, Mujinya, Regan, Nankya, Viola, Keneth Iceland, Kasozi

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Blood-based biomarkers suggest prolonged axonal Injury following pediatric mild traumatic brain injury by Andrew R. Mayer, Tracey V. Wick, Jessica R. McQuaid, Masen L. Boucher, Andrew B. Dodd, Cidney R. Robertson-Benta, Harm J. van der Horn, Erik B. Erhardt, Robert E. Sapien, Rawan Tarawneh, Rebekah Mannix

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Green tea silver nanoparticles improve physiological motor and cognitive function in BALB/c mice during inflammation by Herbert Izo, Ninsiima, Ejike, Daniel Eze, Kenneth, Ssekatawa, Halima, Nalugo, Caroline, Asekenye, David, Onanyang, Edson Ireeta, Munanura, Moses, Ariong, Kevin, Matama, Gerald, Zirintunda, Ngala Elvis, Mbiydzenyuy, Fred, Ssempijja, Adam Moyosore, Afodun, Ibe Michael, Usman, Oscar Hilary, Asiimwe, Julius, Tibyangye, Keneth Iceland, Kasozi

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