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2541
Cross-ViT based benign and malignant classification of pulmonary nodules.
Published 2025-01-01“…Experimental validation was performed on the LUNA16 dataset, and the accuracy, precision, recall and F1 score reached 91.04%, 91.42%, 92.45% and 91.92%, respectively, and the accuracy, precision, recall and F1 score with SENet as CNN branch reached 92.43%, 94.27%, 91.68% and 92.96%, respectively. …”
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2542
PARP Inhibitors in the Treatment of Ovarian Cancer
Published 2025-02-01“…Summary PARP inhibitors represent a significant advancement in ovarian cancer treatment, offering improved survival outcomes for patients with specific genetic profiles. Their integration into standard care protocols underscores their importance and efficacy, providing valuable therapeutic options in the fight against ovarian cancer. …”
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2543
Precision livestock farming applied to the dairy sector: 50 years of history with a text mining and topic analysis approach
Published 2025-03-01“…The global dairy industry has been revolutionized by advancements in genetics, milking technology, nutrition, and farm management, leading to increased milk production per cow and a substantial rise in total annual milk output. …”
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2544
Digital twins as global learning health and disease models for preventive and personalized medicine
Published 2025-02-01“…Disease progression can vary between patients and over time, influenced by genetic and environmental factors. To address this challenge, digital twins have emerged as a promising approach, which have led to international initiatives aiming at clinical implementations. …”
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2545
Comparative analysis of selected methods of carbapenemase determination among clinical Klebsiella pneumoniae.
Published 2025-01-01“…The production of carbapenemases was assessed using phenotypic and genetic methods. The strains tested showed complete resistance to most beta-lactams and varying sensitivity to drugs from the quinolone carbapenem group and aminoglycosides. …”
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2546
Mendelian randomization study of serum uric acid levels and urate-lowering drugs on pulmonary arterial hypertension outcomes
Published 2025-02-01“…This study establishes a genetic basis for a causal link between serum uric acid levels and PAH. …”
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2547
Rudbeckius, Hägglund’s Codex, and the Problem of Authorship Ascription
Published 2024-07-01“… In 1992, Bengt Hägglund put forward a thesis according to which a codex in his possession is based on material Johannes Rudbeckius (1581–1646) authored in 1611, maintaining that the codex gives us information about Rudbeckius's lectures on loci theologici in Uppsala during the years 1611–1613 and that it reveals to us characteristic features of Rudbeckius's thinking about dogmatics. …”
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2548
Haematological and Biochemical Studies on some Ruminants
Published 2013-07-01“…These results could point to definite haematological and biochemical similarities in man and ruminants and thus serves as a springboard for further genetic studies using lower vertebrates research models. …”
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2549
Identification of quantitative trait loci for yield traits and fine-mapping of qGW4 using the chromosome segment substitution line-Z708 and dissected single-segment substitution li...
Published 2025-02-01“…Here, a wide-grain rice chromosome segment substitution line (CSSL), Z708, carrying four substitution segments from Jinhui35 in the genetic background of Xihui18, was used to identify the QTL associated with grain size. …”
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2550
Six events that shaped antibody approvals in oncology
Published 2025-02-01“…Finally, we explore the development of ipilimumab, the first immune checkpoint-inhibiting antibody that activates the immune system to kill cancer cells, and the discovery that allowed the use of checkpoint inhibitors across all cancer types based on the presence of genetic markers. Revisiting these key events provides critical insights into the process of antibody development in oncology.…”
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2551
The Role of Macrophages in the Pathogenesis of Celiac Disease
Published 2024-10-01“…Celiac disease is an autoimmune disease with a characteristic serological (antibodies to tissue transglutaminase, endomysium, deamidated gliadin peptides) and histological profile (inflammatory infiltration of the villous epithelium by lymphocytes and their atrophy, crypt hyperplasia) caused by gluten consumption in genetically predisposed individuals. Macrophages, as key cells that provide a link between innate and adaptive immunity, are of significant importance in the pathogenesis of celiac disease. …”
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2552
Probiogenomic analysis of Limosilactobacillus fermentum SD7, a probiotic candidate with remarkable aggregation abilities
Published 2025-02-01“…These findings provide a comprehensive understanding of the genetic composition of L. fermentum and its potential probiotic properties, identifying L. fermentum SD7 as a promising probiotic candidate for use in the food and healthcare industries.…”
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2553
Introducing a Markov Chain-Based Energy Awareness Approach for Cloud Data Center Virtual Machine Dynamic Management
Published 2024-12-01“…The approach integrates genetic algorithms and refrigeration simulation into the migration replacement process, leveraging absorbing Markov chains for predictive analysis. …”
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2554
Discrete vulnerability to pharmacological CDK2 inhibition is governed by heterogeneity of the cancer cell cycle
Published 2025-02-01“…In cancer models that are genetically independent of CDK2, pharmacological inhibitors suppress cell proliferation by inducing 4N cell cycle arrest and increasing the expressions of phospho-CDK1 (Y15) and cyclin B1. …”
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2555
Knowledge and Perception of Brazilian Dental Students about Molar-Incisor Hypomineralization
Published 2025-02-01“…MIH awareness was significantly associated with fifth-year students (p=0.01). Genetic factors were considered as an etiological factor by 80.6%. …”
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2556
Occurrence of macrolides resistance in Legionella pneumophila ST188: Results of the Belgian epidemiology and resistome investigation of clinical isolates
Published 2025-04-01“…Genotypic screening identified a 23S ribosomal RNA mutation linked to a high-level macrolide resistance in one isolate of ST188, which is genetically closed to resistant isolates from France. …”
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2557
Another new karst-dwelling rock gecko in the Cnemaspis siamensis group (Reptilia, Gekkonidae) from Kanchanaburi Province, western Thailand
Published 2025-02-01“…Phylogenetically, the new species is recovered as the sister taxon to C. huaseesom, but the two species are separated by 8.3–9.4% uncorrected pairwise genetic divergences in the mitochondrial NADH dehydrogenase subunit 2 gene and flanking tRNAs.…”
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2558
Case report: A novel 11-bp deletion in exon 11 causing a frameshift in the C-terminal of the ALAS2 gene leading to X-linked sideroblastic anemia—a family study
Published 2025-02-01“…X-linked sideroblastic anemia (XLSA) (MIM 300752) is the most common genetic form of sideroblastic anemia, a heterogeneous group of disorders characterized by iron deposits in the mitochondria of erythroid precursors. …”
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2559
Trichostatin A suppresses hearing loss by reducing oxidative stress and inflammation in an Alport syndrome model.
Published 2025-01-01“…Alport syndrome (AS) is a genetic disorder marked by mutations in type IV collagen, leading to kidney glomerular dysfunction. …”
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2560
Security protection method based on mimic defense and Paillier encryption for smart IoT terminals
Published 2024-12-01“…First, a security architecture was constructed based on the mimic defense theory to ensure the reliability and robustness of the system even when the edge domain smart terminal had its own security genetic defects. Then, a secure blind signature with Paillier encryption (SBSPE) algorithm was designed in this architecture to safeguard the data and privacy of the edge-area smart terminals throughout the data processing lifecycle of edge-area smart terminals. …”
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