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  1. 2541

    Cross-ViT based benign and malignant classification of pulmonary nodules. by Qinfang Zhu, Liangyan Fei

    Published 2025-01-01
    “…Experimental validation was performed on the LUNA16 dataset, and the accuracy, precision, recall and F1 score reached 91.04%, 91.42%, 92.45% and 91.92%, respectively, and the accuracy, precision, recall and F1 score with SENet as CNN branch reached 92.43%, 94.27%, 91.68% and 92.96%, respectively. …”
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  2. 2542

    PARP Inhibitors in the Treatment of Ovarian Cancer by Andrzej Paweł Zuzak, Magdalena Cieślik-Porębska, Krzysztof Kułak, Jagoda Niewiadomska

    Published 2025-02-01
    “…Summary PARP inhibitors represent a significant advancement in ovarian cancer treatment, offering improved survival outcomes for patients with specific genetic profiles. Their integration into standard care protocols underscores their importance and efficacy, providing valuable therapeutic options in the fight against ovarian cancer. …”
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  3. 2543

    Precision livestock farming applied to the dairy sector: 50 years of history with a text mining and topic analysis approach by Lucia Trapanese, Giovanna Bifulco, Alfio Calanni Macchio, Francesca Aragona, Sissy Purrone, Giuseppe Campanile, Angela Salzano

    Published 2025-03-01
    “…The global dairy industry has been revolutionized by advancements in genetics, milking technology, nutrition, and farm management, leading to increased milk production per cow and a substantial rise in total annual milk output. …”
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  4. 2544

    Digital twins as global learning health and disease models for preventive and personalized medicine by Xinxiu Li, Joseph Loscalzo, A. K. M. Firoj Mahmud, Dina Mansour Aly, Andrey Rzhetsky, Marinka Zitnik, Mikael Benson

    Published 2025-02-01
    “…Disease progression can vary between patients and over time, influenced by genetic and environmental factors. To address this challenge, digital twins have emerged as a promising approach, which have led to international initiatives aiming at clinical implementations. …”
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    Article
  5. 2545

    Comparative analysis of selected methods of carbapenemase determination among clinical Klebsiella pneumoniae. by Agata Pruss, Alicja Skierska, Paweł Kwiatkowski, Helena Masiuk, Joanna Jursa-Kulesza, Stefania Giedrys-Kalemba, Iwona Bilska, Monika Sienkiewicz, Maria V Melnyk, Barbara Dołęgowska

    Published 2025-01-01
    “…The production of carbapenemases was assessed using phenotypic and genetic methods. The strains tested showed complete resistance to most beta-lactams and varying sensitivity to drugs from the quinolone carbapenem group and aminoglycosides. …”
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  6. 2546

    Mendelian randomization study of serum uric acid levels and urate-lowering drugs on pulmonary arterial hypertension outcomes by Xiaoling Yao, Xin Cai, Shaoqin Zhang, Yuzheng Yang, Xiangyan Yang, Wukai Ma, Zong Jiang

    Published 2025-02-01
    “…This study establishes a genetic basis for a causal link between serum uric acid levels and PAH. …”
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  7. 2547

    Rudbeckius, Hägglund’s Codex, and the Problem of Authorship Ascription by Tero Tulenheimo

    Published 2024-07-01
    “… In 1992, Bengt Hägglund put forward a thesis according to which a codex in his possession is based on material Johannes Rudbeckius (1581–1646) authored in 1611, maintaining that the codex gives us information about Rudbeckius's lectures on loci theologici in Uppsala during the years 1611–1613 and that it reveals to us characteristic features of Rudbeckius's thinking about dogmatics. …”
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  8. 2548

    Haematological and Biochemical Studies on some Ruminants by LC Chuku, AA Uwakwe

    Published 2013-07-01
    “…These results could point to definite haematological and biochemical similarities in man and ruminants and thus serves as a springboard for further genetic studies using lower vertebrates research models. …”
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  9. 2549

    Identification of quantitative trait loci for yield traits and fine-mapping of qGW4 using the chromosome segment substitution line-Z708 and dissected single-segment substitution li... by Kai Zhou, Jinjin Yu, Zhaopeng Yu, Chunyu Chi, Jialin Ren, Zhuowen Zhao, Han Zhang, Yinghua Ling, Changwei Zhang, Fangming Zhao

    Published 2025-02-01
    “…Here, a wide-grain rice chromosome segment substitution line (CSSL), Z708, carrying four substitution segments from Jinhui35 in the genetic background of Xihui18, was used to identify the QTL associated with grain size. …”
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  10. 2550

    Six events that shaped antibody approvals in oncology by Suman Paul, Suman Paul, Shibin Zhou, Shibin Zhou

    Published 2025-02-01
    “…Finally, we explore the development of ipilimumab, the first immune checkpoint-inhibiting antibody that activates the immune system to kill cancer cells, and the discovery that allowed the use of checkpoint inhibitors across all cancer types based on the presence of genetic markers. Revisiting these key events provides critical insights into the process of antibody development in oncology.…”
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  11. 2551

    The Role of Macrophages in the Pathogenesis of Celiac Disease by A. I. Khavkin, E. V. Loshkova, E. I. Kondratieva, N. S. Shapovalova, I. R. Grishkevich, I. V. Doroshenko, G. N. Yankina

    Published 2024-10-01
    “…Celiac disease is an autoimmune disease with a characteristic serological (antibodies to tissue transglutaminase, endomysium, deamidated gliadin peptides) and histological profile (inflammatory infiltration of the villous epithelium by lymphocytes and their atrophy, crypt hyperplasia) caused by gluten consumption in genetically predisposed individuals. Macrophages, as key cells that provide a link between innate and adaptive immunity, are of significant importance in the pathogenesis of celiac disease. …”
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  12. 2552

    Probiogenomic analysis of Limosilactobacillus fermentum SD7, a probiotic candidate with remarkable aggregation abilities by Thunchanok Yaikhan, Monwadee Wonglapsuwan, Nuntiya Pahumunto, Natakorn Nokchan, Rawee Teanpaisan, Komwit Surachat

    Published 2025-02-01
    “…These findings provide a comprehensive understanding of the genetic composition of L. fermentum and its potential probiotic properties, identifying L. fermentum SD7 as a promising probiotic candidate for use in the food and healthcare industries.…”
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  13. 2553

    Introducing a Markov Chain-Based Energy Awareness Approach for Cloud Data Center Virtual Machine Dynamic Management by Xinbin Huang, Yu Huang, Cecılıa. Mercado

    Published 2024-12-01
    “…The approach integrates genetic algorithms and refrigeration simulation into the migration replacement process, leveraging absorbing Markov chains for predictive analysis. …”
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  14. 2554

    Discrete vulnerability to pharmacological CDK2 inhibition is governed by heterogeneity of the cancer cell cycle by Vishnu Kumarasamy, Jianxin Wang, Michelle Roti, Yin Wan, Adam P. Dommer, Hanna Rosenheck, Sivasankar Putta, Alec Trub, John Bisi, Jay Strum, Patrick Roberts, Seth M. Rubin, Costakis Frangou, Karen McLean, Agnieszka K. Witkiewicz, Erik S. Knudsen

    Published 2025-02-01
    “…In cancer models that are genetically independent of CDK2, pharmacological inhibitors suppress cell proliferation by inducing 4N cell cycle arrest and increasing the expressions of phospho-CDK1 (Y15) and cyclin B1. …”
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  15. 2555

    Knowledge and Perception of Brazilian Dental Students about Molar-Incisor Hypomineralization by Thalys Gustavo Oliveira Martins, Naiara Oliveira Carvalho, Cristiane Tomaz Rocha, Beatriz Gonçalves Neves

    Published 2025-02-01
    “…MIH awareness was significantly associated with fifth-year students (p=0.01). Genetic factors were considered as an etiological factor by 80.6%. …”
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  16. 2556

    Occurrence of macrolides resistance in Legionella pneumophila ST188: Results of the Belgian epidemiology and resistome investigation of clinical isolates by Charlotte Michel, Fedoua Echahidi, Geraldine De Muylder, Max Sewell, Ian Boostrom, Olivier Denis, Owen B. Spiller, Denis Pierard

    Published 2025-04-01
    “…Genotypic screening identified a 23S ribosomal RNA mutation linked to a high-level macrolide resistance in one isolate of ST188, which is genetically closed to resistant isolates from France. …”
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  17. 2557

    Another new karst-dwelling rock gecko in the Cnemaspis siamensis group (Reptilia, Gekkonidae) from Kanchanaburi Province, western Thailand by Attapol Rujirawan, Akrachai Aksornneam, Siriporn Yodthong, Parinya Pawangkhanant, Bryan L. Stuart, Anchalee Aowphol

    Published 2025-02-01
    “…Phylogenetically, the new species is recovered as the sister taxon to C. huaseesom, but the two species are separated by 8.3–9.4% uncorrected pairwise genetic divergences in the mitochondrial NADH dehydrogenase subunit 2 gene and flanking tRNAs.…”
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  18. 2558

    Case report: A novel 11-bp deletion in exon 11 causing a frameshift in the C-terminal of the ALAS2 gene leading to X-linked sideroblastic anemia—a family study by Salam Al kindi, Salam Al kindi, Altaf Al-Mamari, Shoaib Al-Zadjali, Mohamed Al-Rawahi, Ali Al Madhani, Anil V. Pathare

    Published 2025-02-01
    “…X-linked sideroblastic anemia (XLSA) (MIM 300752) is the most common genetic form of sideroblastic anemia, a heterogeneous group of disorders characterized by iron deposits in the mitochondria of erythroid precursors. …”
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  19. 2559

    Trichostatin A suppresses hearing loss by reducing oxidative stress and inflammation in an Alport syndrome model. by Yoon Seok Nam, Eun-Ji Gi, Yoo-Seung Ko, Sungsu Lee, Hyong-Ho Cho

    Published 2025-01-01
    “…Alport syndrome (AS) is a genetic disorder marked by mutations in type IV collagen, leading to kidney glomerular dysfunction. …”
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  20. 2560

    Security protection method based on mimic defense and Paillier encryption for smart IoT terminals by GU Tiansheng, ZENG Fukang, SHAO Sisi, NIE Yijun, JI Zongkai, ZHENG Yulu, SHI Yuchen, LIU Shangdong, JI Yimu

    Published 2024-12-01
    “…First, a security architecture was constructed based on the mimic defense theory to ensure the reliability and robustness of the system even when the edge domain smart terminal had its own security genetic defects. Then, a secure blind signature with Paillier encryption (SBSPE) algorithm was designed in this architecture to safeguard the data and privacy of the edge-area smart terminals throughout the data processing lifecycle of edge-area smart terminals. …”
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