Adrenal Disorders and the Paediatric Brain: Pathophysiological Considerations and Clinical Implications by Vincenzo Salpietro, Agata Polizzi, Gabriella Di Rosa, Anna Claudia Romeo, Valeria Dipasquale, Paolo Morabito, Valeria Chirico, Teresa Arrigo, Martino Ruggieri

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Rare Somatic MEN1 Gene Pathogenic Variant in a Patient Affected by Atypical Parathyroid Adenoma by Luigia Cinque, Flavia Pugliese, Celeste Clemente, Stefano Castellana, Maria Pia Leone, Danilo de Martino, Teresa Balsamo, Claudia Battista, Tommaso Biagini, Paolo Graziano, Marco Castori, Alfredo Scillitani, Vito Guarnieri

“…We suggest that MEN1 gene could be an underestimate genetic determinant of these rare histological entities, and we highlight the utility of a complete genetic screening protocol, by the use of next-generation sequencing technology in such undetermined clinical cases with no frank clinical presentation.…”
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Differential Dynamics of ATR-Mediated Checkpoint Regulators by Daniël O. Warmerdam, Roland Kanaar, Veronique A. J. Smits

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Gain in 1q is a Common Abnormality in Phyllodes Tumours of the Breast by Kowan J. Jee, Gyungyub Gong, Sei Hyun Ahn, Jeong Mi Park, Sakari Knuutila

“…We studied DNA copy number changes by CGH and allelic imbalance (AI) on 3p by LOH analysis on 22 phyllodes tumours (PT) of the breast in order to gain insight into the genetic basis of tumour progression in PT. Copy number changes were observed in 14 cases (63%). …”
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The Properties of Red Blood Cells from Patients Heterozygous for HbS and HbC (HbSC Genotype) by A. Hannemann, E. Weiss, D. C. Rees, S. Dalibalta, J. C. Ellory, J. S. Gibson

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Left-Right Brain-Wide Asymmetry of Neuroanatomy in the Mouse Brain by Andrew Silberfeld, James M. Roe, Jacob Ellegood, Jason P. Lerch, Lily Qiu, Yongsoo Kim, Jong Gwan Lee, William D. Hopkins, Joanes Grandjean, Yangming Ou, Olivier Pourquié

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X-Linked Autism Type 9 Caused by a Hemizygote Pathogenic Variant in the TMLHE Gene: Etiological Diagnosis in an Adult Male with Moderate Intellectual Disability by Verhoeven WM, Pfundt R, Engelke UF, Kluijtmans LA, Egger JI

“…Lack of TMLH enzyme activity is associated with developmental delay and autistic behaviours described as X-linked recessive autism, type 6 (OMIM#300872).Patient and Methods: Here, an institutionalized adult male patient with intellectual disability, autism, and challenging behaviours is presented in whom genetic analysis disclosed a novel pathogenic variant in the TMLHE gene. …”
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Evidence for the communicative function of human-directed gazing in 6- to 7-week-old dog puppies by Stefanie Riemer, Alina Bonorand, Lisa Stolzlechner

“…They appear to have a genetic preparedness to communicate with humans via gaze alternations early in ontogeny, but they may need close contact with humans for this ability to emerge, highlighting the interactive effects of domestication and environmental factors on behavioural development in dogs.…”
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Prader-Willi Syndrome: Clinical Aspects by Grechi Elena, Cammarata Bruna, Mariani Benedetta, Di Candia Stefania, Chiumello Giuseppe

“…Prader-Willi Syndrome (PWS) is a complex multisystem genetic disorder that shows great variability, with changing clinical features during a patient’s life. …”
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Neural markers of error processing relate to task performance, but not to substance-related risks and problems and externalizing problems in adolescence and emerging adulthood by Olga D. Boer, Thea Wiker, Shervin H. Bukhari, Rikka Kjelkenes, Clara M.F. Timpe, Irene Voldsbekk, Knut Skaug, Rune Boen, Valerie Karl, Torgeir Moberget, Lars T. Westlye, Ingmar H.A. Franken, Hanan El Marroun, Rene J. Huster, Christian K. Tamnes

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Environmental Factors Promoting Neural Plasticity: Insights from Animal and Human Studies by Laura Mandolesi, Francesca Gelfo, Laura Serra, Simone Montuori, Arianna Polverino, Giuseppe Curcio, Giuseppe Sorrentino

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Wharton’s Jelly-Derived Mesenchymal Stromal Cells and Fibroblast-Derived Extracellular Matrix Synergistically Activate Apoptosis in a p21-Dependent Mechanism in WHCO1 and MDA MB 23... by Kevin Dzobo, Matjaz Vogelsang, Nicholas E. Thomford, Collet Dandara, Karlien Kallmeyer, Michael S. Pepper, M. Iqbal Parker

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Alleviating the public health burden of hypertension: debating precision prevention as a possible solution by Madeleine J. Samakosky, Shane A. Norris

“…Precision prevention, a tailored health intervention approach utilising individual and population-specific factors – genetic, environmental, and social determinants – offers a potential alternative. …”
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Sedative and Hypnotic Activities of the Methanolic and Aqueous Extracts of Lavandula officinalis from Morocco by Rachad Alnamer, Katim Alaoui, El Houcine Bouidida, Abdelaziz Benjouad, Yahia Cherrah

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Addressing challenges in vector control: a review of current strategies and the imperative for novel tools in India’s combat against vector-borne diseases by Kuldeep Singh, Amit Sharma, Manju Rahi, Sanjeev Kumar Gupta, Gaurav Kumar, Rajendra Baharia, Sam Joy

“…However, these methods are increasingly becoming less effective due to several reasons such as insecticide resistance, outdoor biting, behavioural changes in vectors for biting and resting, climate change, movement of population, vector incursion to newer areas and others. …”
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Closing the gap in dementia research by community-based cohort studies in the Chinese populationResearch in context by Xiaowen Zhou, Zhenxu Xiao, Wanqing Wu, Yuntao Chen, Changzheng Yuan, Yue Leng, Yao Yao, Qianhua Zhao, Albert Hofman, Eric Brunner, Ding Ding

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Ensuring ethical animal welfare research: Are more ethics review committees the solution? by Nielsen, Birte L., Golledge, Huw D. R., Chou, Jen-Yun, Camerlink, Irene, Pongrácz, Péter, Ceballos, Maria Camila, Whittaker, Alexandra L., Olsson, I. Anna S.

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Opposite roles of serotonin and neuropeptide FMRFamide in the regulation of epigenetic processes involved in the longterm memory formation by L. N. Grinkevich, O. V. Vorobiova

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Precision livestock farming applied to the dairy sector: 50 years of history with a text mining and topic analysis approach by Lucia Trapanese, Giovanna Bifulco, Alfio Calanni Macchio, Francesca Aragona, Sissy Purrone, Giuseppe Campanile, Angela Salzano

“…The global dairy industry has been revolutionized by advancements in genetics, milking technology, nutrition, and farm management, leading to increased milk production per cow and a substantial rise in total annual milk output. …”
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Huntington Disease Health Related Quality of Life, Function and Well Being: The Patient’s Perspective by Jesús Pérez-Pérez, Sofía García-López, Tamara Fernández Valle, Cèlia Painous, Maria Rosa Querol-Pascual, Pedro J. García Ruiz, Elena Bellosta Diago, Esther Cubo Delgado, Barbara Vives Pastor, María Carmen Peiró Villaplana, Idaira Martín Santana, Marta Blázquez Estrada, Matilde Calopa Garride, Pablo Mir, Carmen Álvarez, Jorge Maurino, Anna de Prado, José Luis López-Sendón

“…Patients aged ≥ 18 years, genetically HD diagnosed [with a diagnostic confidence level score of 4, and an Independence Scale (IS) score ≥ 70] were included. …”
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