The health status of hybrid grouper Epinephelus fuscoguttatus (♀) x E.lanceolatus (♂) cultured in floating-net cage at Kelapa Dua Island, Seribu Islands, Indonesia by Ruku Ratu Borut, Sukenda, Sri Nuryati, kukuh Nirmala, Irzal Effendi, Widanarni

“…Hasil pengamatan menunjukkan perubahan tingkah laku ikan sakit yaitu  berputar ke atas permukaan KJA, terjadi sleeping dead atau ikan berada di dasar seperti mati. Ikan kerapu cantang memiliki jumlah eritrosit 1.36 x 106 – 5.13 x 106 sel/mm3, leukosit 2.9 x 104 – 7.9 x 104 sel/mm3, hemoglobin 5.56 - 10.94 gr  %, dan hematokrit 13.31 - 24.78 %, hasil histopalogi ikan mengalami perubahan sel pada hati yaitu hepatosit, vakuolisasi, nekrosis dan ginjal mengalami perubahan infiltrasi leukosit, nicrosis, tubulus dan kehadiran virus VNN tertinggi berkisar 20 % - 80 %. …”
Get full text

Implementasi Fuzzy C-Means untuk Pengelompokan Daerah berdasarkan Persebaran Penularan Covid-19 by Gibran Satya Nugraha, Ramaditia Dwiyansaputra, Fitri Bimantoro, Arik Aranta

“…Seperti pada data harian kasus per provinsi di akhir bulan April 2021 dimana kasus positif dan sembuh terbanyak terdapat pada Provinsi DKI Jakarta, untuk kasus meninggal Provinsi Jawa Timur berada di posisi pertama, dan di posisi empat untuk kasus positif dan meninggal. …”
Get full text

Implementasi Web Push Notification pada Sistem Informasi Manajemen Arsip Menggunakan PUSHJS by Alam Rahmatulloh, Andi Nur Rachman, Fahmi Anwar

“…But there is no process behind the scenes so that it will not be run automatically, the problem is overcome by using AJAX by retrieving JSON and then running repeatedly on the web browser and minimizing clashes between web push notification scripts on multi tab windows or web browser windows resolved using localStorage from the HTML5 WebStorage API. …”
Get full text

Segmentasi Pelanggan Ritel Produk Farmasi Obat Menggunakan Metode Data Mining Klasterisasi Dengan Analisis Recency Frequency Monetary (RFM) Termodifikasi by Arief Wibowo, Andy Rio Handoko

“…Hasil penelitian menunjukkan bahwa segmentasi pelanggan yang optimal berada pada dua klaster berdasarkan hasil analisis QRF (Quantity, Recency dan Frequency) menggunakan evaluasi Davies Bouldin Indeks (DBI) dengan nilai 0,527. …”
Get full text

Penerapan Mekanisme Continuous Deployment dalam Pengembangan dan Pembaruan Perangkat Lunak Sistem Benam Berbasis Internet of Things by Yohanna Fransiska Aladina, Adhitya Bhawiyuga, Reza Andria Siregar, Primantara Hari Trisnawan

“…Namun selama ini, proses pembaruan perangkat IoT memiliki permasalahan yang serius terkait biaya dan waktu, yaitu ketika hendak melakukan pembaruan software, manusia harus datang secara langsung ke lokasi di mana perangkat IoT tersebut berada. Dari permasalahan tersebut, maka dibuatlah penelitian ini mengenai pembaruan software pada perangkat IoT menggunakan continuous deployment yang dilakukan di cloud. …”
Get full text

Karakteristik Klinis dan Patologis Karsinoma Nasofaring di Bagian THT-KL RSUP Dr.M.Djamil Padang by Shofi Faiza, Sukri Rahman, Aswiyanti Asri3 Asri

“…Sebagian besar pasien berada pada stadium IV 83,16%, dengan derajat tumor terbanyak T4N2M0 15,91%. …”
Get full text

Distinguishable Immunologic Characteristics of COVID-19 Patients with Comorbid Type 2 Diabetes Compared with Nondiabetic Individuals by Ruxing Zhao, Yujing Sun, Yongyuan Zhang, Weili Wang, Shouyu Wang, Chuang Wang, Jinbo Liu, Ling Gao, Zhao Hu, Jianchun Fei, Xinguo Hou, Huizhen Zheng, Li Chen

“…And Th1/Th2 cytokines (IL-2, IL-4, IL-6, IL-10, TNF-α, and IFN-γ) were detected by Cytometric Bead Array. Results. Neutrophil counts were found to be significantly higher in the T2D group than in the NDM group and had a significant relevance with clinical severity. …”
Get full text

Regulatory T Cell Phenotype Related to Cytokine Expression Patterns in Post‐COVID‐19 Pulmonary Fibrosis and Idiopathic Pulmonary Fibrosis by Sara Gangi, Laura Bergantini, Irene Paggi, Marco Spalletti, Paolo Cameli, Elena Bargagli, Miriana d'Alessandro

“…PB samples were collected, and CD4‐ and CD8‐T subsets were analyzed through flow cytometry. Multiplex bead‐based LEGENDplex™ were used for cytokine quantification. …”
Get full text

Towards an Automated Design Evaluation Method for Wire Arc Additive Manufacturing by Johannes Pusicha, Henrik Stromberg, Markus Quanz, Armin Lohrengel

“…To apply the literature design rules regarding wall thickness, clearance, bead angle, and edge radius to specific geometry regions, features are classified by the indicators. …”
Get full text

Age-related changes in DNA methylation in a sample of elderly Brazilians by Hayley Welsh, Caio M. P. F. Batalha, Weili Li, Nadja C. Souza-Pinto, Yeda A. O. Duarte, Michel S. Naslavsky, Esteban J. Parra

“…Methods DNAm profiles were collected approximately nine years apart from 23 elderly Brazilian individuals using the Illumina Infinium MethyationEPIC BeadChip. Using mixed-effects models, we examined changes in DNAm patterns using both quantitative age and binary timepoint (e.g., baseline vs. follow-up) as predictors of interest to identify differentially methylated positions (DMPs). …”
Get full text

An exceptionally rare case of a diffuse midline glioma with concomitant H3.1 K27M and G34R mutations in the HIST1H3C (H3C3) gene by Zita Reisz, Rita Pereira, Smitha Nevis, Alan Mackay, Leena Bhaw, Yura Grabovska, Ross Laxton, Valeria Molinari, Anna Burford, Barnaby Clark, Cristina Bleil, Bassel Zebian, Erika Pace, Annette Weiser, Fernando Carceller, Lynley Marshall, Andrew King, Istvan Bodi, Safa Al-Sarraj, Chris Jones, Matthew Clarke

“…DNA methylation profiling (Illumina EPIC BeadArrays, brain tumour classifier (MNP v12.5 R package)) classified the tumour as ‘DMG, H3 K27-altered’ (calibrated score = 0.99). …”
Get full text

Urine proteomics defines an immune checkpoint-associated nephritis signature by Cassian Yee, Jamie S Lin, James P Long, Shailbala Singh, Yanlan Dong

“…However, identification of effective biomarkers of disease using established technologies such as proximity ligation assays (PLA) and bead-based immunoassays is challenging due to their limited sensitivity and loss of precision in multiplex analysis.To address this, we employed cutting-edge NUcleic acid Linked Immuno-Sandwich Assay (NULISA) technology to measure protein expression in urine and plasma samples from AKI patients undergoing ICI therapy. …”
Get full text

Functional heterogeneity of mesenchymal stem cells and their therapeutic potential in the K18-hACE2 mouse model of SARS-CoV-2 infection by Kátia Nunes da Silva, Fernanda Martins Marim, Gisele Vieira Rocha, Zaquer Suzana Munhoz Costa-Ferro, Luciana Souza de Aragão França, Carolina Kymie Vasques Nonaka, Bruno Diaz Paredes, Erik Aranha Rossi, Erick Correia Loiola, Corynne Stephanie Ahouefa Adanho, Rachel Santana Cunha, Mayck Medeiros Amaral da Silva, Fernanda Ferreira Cruz, Vivian Vasconcelos Costa, Dalila Lucíola Zanette, Clarissa Araújo Gurgel Rocha, Renato Santana Aguiar, Patricia Rieken Macedo Rocco, Bruno Solano de Freitas Souza

“…In co-culture assays with lymphocytes activated with anti-CD3/CD28 beads, all MSC lines demonstrated the ability to inhibit TNF-α, to induce TGF-β and Indoleamine 2,3-dioxygenase (IDO), with varying degrees of inhibition observed for IFN-γ and IL-6, or induction of IL-10 expression. …”
Get full text

Systemic Resolvin E1 (RvE1) Treatment Does Not Ameliorate the Severity of Collagen-Induced Arthritis (CIA) in Mice: A Randomized, Prospective, and Controlled Proof of Concept Study by Rafael Scaf de Molon, Rogier M. Thurlings, Birgitte Walgreen, Monique M. Helsen, Peter M. van der Kraan, Joni Augusto Cirelli, Marije I. Koenders

“…Moreover, human RA synovial explants were incubated with 1 nM, 10 nM, or 100 nM of RvE1, and cytokine levels (IL-1β, IL-6, IL-8, IL-10, INF-γ, and TNF-α) were measured using Luminex bead array. CIA triggered significant inflammation in the synovial cavity, proteoglycan loss, and cartilage and bone destruction in the ankle joints of mice. …”
Get full text

PENGEMBANGAN INSTRUMEN PENILAIAN HASIL BELAJAR FISIKA BERORIENTASI HOTS (Higher Order Thinking Skills) PADA MATERI ELASTISITAS DAN HUKUM HOOKE by Dona Desilva, Indra Sakti, Rosane Medriati

“…Hasil penelitian dan pengembangan menunjukkan bahwa 1) desain instrumen HOTS memiliki bentuk soal pilihan ganda dan uraian, disajikan sebagai paper test dengan konteks soal di luar kelas (kontekstual) dan materi Elastisitas dan Hukum Hooke serta indikator soal HOTS, 2) hasil uji validitas atau judgement ahli dan praktisi berada pada kategori sangat valid dengan peesentase 97,14% untuk aspek materi, 98,33% untuk aspek konstruksi dan 100% untuk aspek bahasa, dan 3) karakterisitik instrumen HOTS mengacu pada indikator HOTS (pada level kognitif C4 atau C5 atau C6), menggunakan Kata Kerja Operasional (KKO) level C4 atau C5 atau C6, kontekstual dan menggunakan stimulus (teks, gambar, tabel)).   …”
Get full text

The Metempiricism of Margins: Professor Anthony Aṣiwaju and the Circumference of Knowledge by Toyin Falola

“… Professor Anthony Aṣiwaju has written his memoir, Bridging Boundaries, to commemorate his 80th birthday, thus giving us a treasure to behold, a legacy to cherish, and a history to keep. …”
Get full text

Dva příběhy z kriminálního podsvětí – padělatelé peněz na hradě Žampachu a přepadání Židů v roce 1542 by František Šebek

“…On July 10th 1542 Jan Krška and Jiří Vodička, convicted of counterfeiting money, were burnt at the stake in Pardubice; Pavel of Nový Hrádek was hung for his offences. The main person behind the counterfeiting workshop, the smith Jan of Žampach, was then arrested. …”
Get full text

Stilistika Al-Qur'an: Suatu Analisis Linguistik by Juwairiyah Siregar, Agustiar

“…The aim of this field is to reveal and explain the meaning behind the use of beautiful language in a text. The scope of the study of stylistics includes various linguistic elements, namely phonology, morphology, syntax and semantics, to understand the meaning and style of language contained in a text. …”
Get full text

La question du logement social à New York by Catherine Pouzoulet

“…The 1930’s—and the political forces at work behind the scenes at local and federal level—were thus to shape the decades to come as the initial vision of a unified federal housing program was defeated by the emergence of a two‑tiered approach. …”
Get full text

Evaluation of karamunting Melastoma malabathricum L leaf extract on gonad development and growth performance of tilapia Oreochromis niloticus by Ermianus Samalei, Muhammad Zairin Jr., Odang Carman, Muhammad Agus Suprayudi

“…Hasil histologi terakhir (D112) menunjukkan bahwa perlakuan 1 g/kg pakan mengindikasikan penghambatan perkembangan testis dan ovari yang paling besar yang masing-masing berada pada TKG II, dibandingkan dengan perlakuan 0,5 g/kg pakan (TKG III), dan dibandingkan dengan kontrol (TKG IV dan TKG V). …”
Get full text