Is Anonymization Through Discretization Reliable? Modeling Latent Probability Distributions for Ordinal Data as a Solution to the Small Sample Size Problem by Stefan Michael Stroka, Christian Heumann

“…Evaluated with synthetic datasets and real-world datasets from UCI and Kaggle, our method shows improved mean point estimation and narrower prediction intervals compared to the baseline. With 5–10% training data randomly split from each dataset population, it achieves an average 10% reduction in <i>MSE</i> and a ~5–10% increase in <i>R</i>² on out-of-sample test data overall.…”
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Crizanlizumab and comparators for adults with sickle cell disease: a systematic review and network meta-analysis by George Joseph, Howard Thom, Jeroen Jansen, Hung-Yuan Cheng, Jason Shafrin, Lauren Zhao, Subhajit Gupta, Nirmish Shah

“…The NMA found that crizanlizumab 5.0 mg/kg was associated with a reduction in VOC (HR 0.55, 95% credible interval (0.43, 0.69); Bayesian probability of superiority &gt;0.99), all-cause hospitalisation days (0.58 (0.50, 0.68); &gt;0.99) and no evidence of difference on adverse events (0.91 (0.59, 1.43) 0.66) or serious adverse events (0.93 (0.47, 1.87); 0.59) compared with placebo. …”
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Pharmacokinetic Model‐Informed Precision Dosing of Natalizumab in Multiple Sclerosis by Stefan P. H. van denBerg, Alyssa A. Toorop, Femke Hooijberg, Gertjan Wolbink, Nivea M. F. Voelkner, Liza M. Y. Gelissen, Joep Killestein, Zoé L. E. vanKempen, Thomas P. C. Dorlo, Theo Rispens

“…Simulating MIPD showed a reduction in the average infusions versus the standard interval by 40%, with an average dose interval of 7 weeks, while maintaining adequate drug exposure. …”
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Analyzing the dynamics of complicated and uncomplicated appendicitis during the COVID-19 pandemic in Seoul, Korea: a multifaceted time series approach by Kiook Baek, Chulyong Park

“…The BSTS model demonstrated a 7.8% reduction in total appendicitis cases (95% credible interval [CrI], -12.1 to -3.3). …”
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Modeling of the temporal patterns of fluoxetine prescriptions and suicide rates in the United States. by Michael S Milane, Marc A Suchard, Ma-Li Wong, Julio Licinio

“…Mathematical modeling of what suicide rates would have been during the 1988-2002 period based on pre-1988 data indicates that since the introduction of fluoxetine in 1988 through 2002 there has been a cumulative decrease in expected suicide mortality of 33,600 individuals (posterior median, 95% Bayesian credible interval 22,400-45,000).<h4>Conclusions</h4>The introduction of SSRIs in 1988 has been temporally associated with a substantial reduction in the number of suicides. …”
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Socio-economic disparities in the burden of seasonal influenza: the effect of social and material deprivation on rates of influenza infection. by Katia M Charland, John S Brownstein, Aman Verma, Stephanie Brien, David L Buckeridge

“…<h4>Results</h4>Deprivation scores ranged from one to five with five representing the highest level of deprivation. We found a 21% reduction in rates for every 1 unit increase in social deprivation score (rate ratio [RR] 0.79, 95% Credible Interval [CrI] 0.66, 0.97). …”
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Environmental and geographical factors influence malaria transmission in KwaZulu-Natal province, South Africa by Osadolor Ebhuoma, Michael Gebreslasie, Oswaldo Villena, Ali Arab

“…Our findings indicate that the best model was the Zero- Inflated Negative Binomial (ZINB) and that at 95% Bayesian Credible Interval (CI), NDVI (0.74; CI (0.95, 3.87) is significantly related to malaria transmission in KZN, with the north-eastern part of the province exhibiting the highest risk of malaria transmission. …”
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Network meta-analysis of cadmium toxicity against Chlorella vulgaris and the role of growth stimulants and macronutrients by M. Iqhrammullah, S. Saudah, M. Monalisa, F. Fahrurrozi, S.A. Akbar, S.S. Lubis

“…The collected data were then subjected to Bayesian frequentist network meta-analysis, utilizing standardized mean difference and a 95 percent confidence interval as measures of effect size. …”
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Optimising a multi-strategy implementation intervention to improve the delivery of a school physical activity policy at scale: findings from a randomised noninferiority trial by Cassandra Lane, Luke Wolfenden, Alix Hall, Rachel Sutherland, Patti-Jean Naylor, Chris Oldmeadow, Lucy Leigh, Adam Shoesmith, Adrian Bauman, Nicole McCarthy, Nicole Nathan

“…The mean total cost was AUD$25,375 (95% uncertainty interval = $21,499, $29,106) for PACE and AUD$16,421 (95% uncertainty interval = $13,974, $19,656) for Adapted PACE; an estimated reduction of AUD$373 (95% uncertainty interval = $173, $560) per school. …”
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Modelling the impact of climatic and environmental variables on malaria incidence in Tanzania: Implications for achieving the WHO's 2030 Targets. by Angelina Mageni Lutambi, Basiliana Emidi, Fredrick George Mbuya, Michael Ryoba, Thadei Damas Sagamiko, Alfred Kisuda Hugo, Isambi Sailon Mbalawata

“…We utilized geo-covariate data from the Demographic and Health surveys (DHS) program, applying a Moran's I test for spatial autocorrelation, a geostatistical Bayesian-based model to predict malaria incidence at an unsampled locations, and calculated the percentage change in predicted incidence over a ten-year interval. …”
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Ecological responses to blue water MPAs. by Eric Gilman, Milani Chaloupka, Mark Fitchett, Danielle L Cantrell, Matt Merrifield

“…Catch rates of bigeye tuna, the main target species (Kingman/Palmyra MPA, causal effect probability >99% of an 84% reduction; 95% credible interval: -143%, -25%), and blue shark (Johnston MPAs, causal effect probability >95%) were significantly lower and longnose lancetfish significantly higher (Johnston MPAs, causal effect probability >95%) than predicted had the MPAs not been established, possibly from closing areas near shallow features, which aggregate pelagic predators, and from 'fishing-the-line'. …”
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Assessing the effectiveness of travel control measures in preventing imported COVID-19 cases reveals the critical role of travel volume by Mingwei Li, Karen A. Grépin, Ru Zhang, Benjamin J. Cowling, Bingyi Yang

“…Results: Stringent travel measures prevented 9821 (9065 – 10,564) importations from entering Hong Kong. Travel volume reductions had the greatest impact (93.0 % reduction, 95 % confidence interval, CI: 91.9 %-93.9 %), followed by mandatory quarantine (80.8 % reduction, 95 % CI: 75.7 % - 87.1 %). …”
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Open-Circuit Fault Diagnosis Method of Energy Storage Converter Based on MFCC Feature Set by Bin YU, Xingrong SONG, Ting ZHOU, Linbo LUO, Hui LI, Liang CHE

“…Firstly, the three-phase current on the alternating current (AC) side is taken as the input signal, and an MFCC fault feature data set is constructed by analyzing the signal spectrum energy distribution and envelope characteristics in different frequency intervals. Then, through kernel principal component analysis (KPCA), the dimension reduction screening of nonlinear fault features under charge and discharge conditions is realized. …”
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Impact of non-pharmacological interventions on the first wave of COVID-19 in Portugal 2020 by Dinis B. Loyens, Constantino Caetano, Carlos Matias-Dias

“…Methods: A compartmental SEIR (Susceptible, Exposed, Infectious, Removed) model was employed to simulate the first COVID-19 wave in Portugal, using a Bayesian approach and symptom-onset incidence data. …”
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Prevention of venous thromboembolic events in patients with lower leg immobilization after trauma: Systematic review and network meta-analysis with meta-epsidemiological approach. by D Douillet, C Chapelle, E Ollier, P Mismetti, P-M Roy, S Laporte

“…Compared to the control group, rivaroxaban, fondaparinux, and low molecular weight heparins were associated with a significant risk reduction of major VTE with an odds ratio of 0.02 (95% credible interval (CrI) 0.00 to 0.19), 0.22 (95% CrI 0.06 to 0.65), and 0.32 (95% CrI 0.15 to 0.56), respectively. …”
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Use of a Personalised Early Warning Decision Support System for Acute Exacerbations of Chronic Obstructive Pulmonary Disease: Results of the “Predict & Prevent” Phase III Trial by Eleni Gkini, Rajnikant L. Mehta, Sarah Tearne, Lucy Doos, Sue Jowett, Nicola Gale, Alice M. Turner

“…Admissions per participant due to AECOPD at 12 months was lower with COPDPredict™: Incidence rate ratio (IRR) 0.64 (95% CI 0.19–2.17, p = 0.478). Exploratory Bayesian analysis and sensitivity analyses saw similar results. …”
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Trends and projections of the disease burden of vitamin A deficiency in China from 1990 to 2021 by Feng Chen, Zixue Gu, Zheng Shi, Shiyun Li, Rong Peng

“…The Joinpoint regression model was used to analyze temporal trends, calculating the estimated annual percentage change (EAPC) and its 95% confidence interval (CI). The Bayesian Age-Period-Cohort (BAPC) model was employed to integrate age, period, and cohort effects for predicting China’s VAD disease burden from 2022 to 2050.ResultsFrom 1990 to 2021, the Age-Standardized Incidence Rate (ASIR), Age-Standardized Prevalence Rate (ASPR), and Age-Standardized Disability-Adjusted Life Year Rate (ASR-DALYs) of VAD in China showed a significant downward trend, with Estimated Annual Percentage Change (EAPC) values of −5.31 (95% CI: −5.65 to −4.96), −5.31 (95% CI: −5.66 to −4.96), and −3.86 (95% CI, −4.84 to −2.86), respectively. …”
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Global, regional, and national impact of Down syndrome on child and adolescent mortality from 1980 to 2021, with projections to 2050: a cross-sectional study by Erdengqieqieke Ye, Erman Wu, Erman Wu, Rui Han, Rui Han

“…Furthermore, BAPC model projections indicate a sustained reduction in mortality for children and adolescents with Down syndrome. …”
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Impact of active case finding for tuberculosis with mass chest X-ray screening in Glasgow, Scotland, 1950-1963: An epidemiological analysis of historical data. by Peter MacPherson, Helen R Stagg, Alvaro Schwalb, Hazel Henderson, Alice E Taylor, Rachael M Burke, Hannah M Rickman, Cecily Miller, Rein M G J Houben, Peter J Dodd, Elizabeth L Corbett

“…With the intervention in 1957, there was a doubling in the pulmonary CNR (RR: 1.95, 95% uncertainty interval [UI] [1.81, 2.11]) and 35% decline in the year after (RR: 0.65, 95% UI [0.59, 0.71]). …”
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Single-round performance of colorectal cancer screening programs: a network meta-analysis of randomized clinical trials by Teruhiko Terasawa, Toshihiro Tadano, Koichiro Abe, Seiju Sasaki, Satoyo Hosono, Takafumi Katayama, Keika Hoshi, Tomio Nakayama, Chisato Hamashima

“…Abstract Background Demonstrating mortality reduction in new colorectal cancer (CRC) screening programs through randomized clinical trials (RCTs) is challenging. …”
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