Educational Attainment Level and Risk of Mortality and Cardiopulmonary Outcomes in High‐Risk Patients With Cardiovascular Disease: The INVESTED Trial by Mats C. H. Lassen, Nicholas Howell, Brian L. Claggett, Tor Biering‐Sørensen, Orly Vardeny, Scott D. Solomon, Jacob Udell, Jacob Joseph, Sheila M. Hegde

“…Background Educational attainment level (EAL) is an indicator of socioeconomic status and has been shown to be inversely related with adverse health outcomes. …”
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Consequences of anemia in geriatric hip fractures: how low is too low? by Alicia Mangram, Kimberli Bruce, Joseph F Sucher, Nuria Blake, Charles D Balcome, Laura Prokuski, James Dzandu, Jeffrey F Barletta, Gina R Shirah

“…Background The transfusion threshold for low hemoglobin (Hgb) in geriatric patients with hip fractures is widely debated. …”
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Intracerebral haemorrhage laterality and associations with mood and pain: a MISTIE III substudy by Issam Awad, Daniel Hanley, Wendy C Ziai, Matthew L Flaherty, Mario Zuccarello, Radhika Avadhani, Noeleen Ostapkovich, Dawson C Cooper, Efrat Abramson, Vishank A Shah, Lourdes Carhuapoma, Lauren H Sansing

“…Background The prognostic significance of the affected hemisphere in haemorrhagic stroke remains uncertain. …”
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MAGGIC risk score and drug-related adverse events of sacubitril/valsartan: Insights from the REVIEW-HF registry by Daiki Akagaki, Tatsuhiro Shibata, Kodai Shibao, Koshiro Kanaoka, Takahito Nasu, Shunsuke Ishii, Nobuyuki Kagiyama, Keisuke Kida, Wataru Fujimoto, Atsushi Kikuchi, Takeshi Ijichi, Yoshihiro Fukumoto, Shingo Matsumoto

“…Background: Although the Meta-Analysis Global Group in Chronic Heart Failure (MAGGIC) risk score is a validated mortality risk tool in heart failure (HF), its utility in assessing drug-related adverse events (DAEs) associated with sacubitril/valsartan initiation remains unclear. …”
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The temporal onset of associations of cortical proteins with cognitive resilience vary during late life by Andrea R. Zammit, Tianhao Wang, Lei Yu, Shahram Oveisgharan, Vladislav A. Petyuk, Philip L. De Jager, Julie A. Schneider, David A. Bennett, Aron S. Buchman

“…Background: Cortical proteins associated with cognitive resilience have been identified but their temporal onset in older adults is unknown. …”
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Implications of Tricuspid Regurgitation Severity in Patients Undergoing Mitral Transcatheter Edge‐to‐Edge Repair by Alon Shechter, Homa Taheri, Takashi Nagasaka, Aakriti Gupta, Danon Kaewkes, Vivek Patel, Kazuki Suruga, Manvir Dhillon, Keita Koseki, Ofir Koren, Moody Makar, Sabah Skaf, Dhairya Patel, Tarun Chakravarty, Robert J. Siegel, Raj R. Makkar

“…We aimed to explore the prevalence, correlates, and consequences of TR grades and postprocedural trends in this setting. Methods and Results A single‐center registry of isolated, first‐time interventions was retrospectively assessed for pre‐, intra‐, and postprocedural aspects up to 1 year, of them the primary composite outcome of all‐cause deaths or heart failure (HF) hospitalizations, all according to TR severity at baseline and at 1 month following mitral transcatheter edge‐to‐edge repair. …”
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Association of Systemic Inflammatory Response Syndrome With Cardiovascular Events After Mitral Transcatheter Edge‐to‐Edge Repair by Carlo Mannina, Akarsh Sharma, Andreina Carbone, Eduardo Bossone, Antonino Tuttolomondo, Edgar Argulian, Eric Neibart, Michael B. Hadley, Jonathan Halperin, George Dangas, Samin K. Sharma, Annapoorna Kini, Stamatios Lerakis

“…Background Systemic inflammatory response syndrome (SIRS) following cardiovascular interventions is associated with adverse events during hospitalization and follow‐up. …”
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Exploring Ethical, Cultural, and Transnational Competence Among International Healthcare Management Students: An Australian Perspective by Howard M, Tan KL, Jayasekara R

“…This exploratory study examined the challenges faced by these students to establish foundational understanding of the competencies needed for effective ethical decision-making, cultural integration, and transnational readiness in diverse healthcare environments.Methods: Using a composite theoretical framework incorporating Cultural Relativism, Ethical Climate Theory, Institutional Theory, and Transnationalism, a 35-item instrument was adapted from three validated sources. …”
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Safety and Efficacy of Different Stent Strategies in Percutaneous Coronary Intervention by Waqas Ullah, MD, RPVI, Harigopal Sandhyavenu, MD, Syeda Ramsha Zaidi, MD, Mileydis Alonso, MD, Muhammad Atif Khan, MD, Irfan Ullah, MBBS, Farah Yasmin, MD, Aravind Reddy Polam, MD, Salman Zahid, MD, Arnav Kumar, MD, MSCR, Ewout W. Steyerberg, MSc, PhD, Mohammad Murtaza, MD, Chadi Alraiesm, MD, MPH, Jeffrey J. Rade, MD

“…Background: The utility of polymer-permanent, polymer-absorbable, and polymer-free drug-eluting stents (DES) in the context of different eluting drugs in patients undergoing percutaneous coronary intervention (PCI) remains controversial. …”
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Outcomes of Cardiac Resynchronization Therapy by New York Heart Association Class: A Patient‐Level Meta‐Analysis by Nishkala Shivakumar, Daniel J. Friedman, Marat Fudim, William T. Abraham, John G. F. Cleland, Anne B. Curtis, Michael R. Gold, Valentina Kutyifa, Cecilia Linde, James Young, Anthony Tang, Antonio Olivas‐Martinez, Lurdes Y.T. Inoue, Gillian D. Sanders, Sana M. Al‐Khatib

“…Background Data on the benefits of cardiac resynchronization therapy (CRT) in patients with severe heart failure symptoms are limited. …”
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Allostatic Load/Chronic Stress and Cardiovascular Outcomes in Patients Diagnosed With Breast, Lung, or Colorectal Cancer by Nickolas Stabellini, Jennifer Cullen, Marcio S. Bittencourt, Justin X. Moore, Arnethea Sutton, Priyanshu Nain, Nelson Hamerschlak, Neal L. Weintraub, Susan Dent, Meng‐Han Tsai, Amitava Banerjee, Arjun K Ghosh, Diego Sadler, Steven S. Coughlin, Ana Barac, John Shanahan, Alberto J. Montero, Avirup Guha

“…Background Cardiovascular disease and cancer share a common risk factor: chronic stress/allostatic load (AL). …”
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Impact of Atrial Fibrillation in Patients With Severe Mitral Regurgitation Undergoing Transcatheter Edge‐to‐Edge Repair by Carlo Mannina, Akarsh Sharma, Yash Prakash, Andreina Carbone, Eduardo Bossone, Antonino Tuttolomondo, Edgar Argulian, Sahil Khera, Parasuram Melarcode‐Krishnamoorthy, George Dangas, Jonathan Halperin, Gilbert H. L. Tang, Samin Sharma, Annapoorna Kini, Gregg W. Stone, Stamatios Lerakis

“…Background Atrial fibrillation (AF) and mitral regurgitation (MR) are closely linked, and one may worsen the other. …”
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Associations Between Gene Variants of Lipid‐Lowering Drug Targets and Adverse Outcomes After Ischemic Stroke by Lulu Sun, Qilu Zhang, Mengyao Shi, Yang Liu, Zhengbao Zhu, Jing Zhang, Hao Peng, Aili Wang, Jing Chen, Tan Xu, Yonghong Zhang, Jiang He

“…Background The association of lipid‐lowering drug targets and their gene variants with cardiovascular diseases has been previously clarified. …”
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Evaluation of mobile health technology combining telemonitoring and teleintervention versus usual care in vulnerable-phase heart failure management (HERMeS): a multicentre, randomi... by Sergi Yun, MD, ProfPhD Josep Comín-Colet, MD, Esther Calero-Molina, RN, Encarnación Hidalgo, RN, Núria José-Bazán, RN, Marta Cobo Marcos, MD, Teresa Soria, RN, Pau Llàcer, PhD, Cristina Fernández, MSc, José Manuel García-Pinilla, PhD, Concepción Cruzado, RN, Álvaro González-Franco, MD, Eva María García-Marina, RN, José Luis Morales-Rull, PhD, Cristina Solé, MD, Elena García-Romero, MD, Julio Núñez, PhD, José Civera, RN, Coral Fernández, RN, Mercedes Faraudo, RN, Pedro Moliner, PhD, Francesc Formiga, PhD, Javier de-Juan Bagudá, MD, Isabel Zegri-Reiriz, PhD, José María Verdú-Rotellar, PhD, Emili Vela, PhD, David Monterde, MSc, Jordi Piera-Jiménez, PhD, Gerard Carot-Sans, PhD, Cristina Enjuanes, PhD, Santiago Jiménez-Marrero, Alberto Garay, Raúl Ramos-Polo, Alexandra Pons-Riverola, Herminio Morillas, Sílvia Jovells-Vaqué, Marta Tajes, Rafael de la Espriella, Elisa Esther Rodríguez, Jessica Paola Rugeles, Maria del Carmen Moreno, Carla Castillo, Ainhoa Robles-Mezcua, Ramon Bascompte, Paola Macarena Beltran Troncoso, Rocío Rodríguez, Román Freixa Pamias, Olga Guri, Cristina Delso Gafarot, Sònia Sarret Vila, Angelique-Casas Thomsen, Jordi Fernández

“…Summary: Background: The potential of mobile health (mHealth) technology combining telemonitoring and teleintervention as a non-invasive intervention to reduce the risk of cardiovascular events in patients with heart failure during the early post-discharge period (ie, the vulnerable phase) has not been evaluated to our knowledge. …”
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Safety and Efficacy of Cobalt Chromium Everolimus‐Eluting Stents for Treatment of In‐Stent Restenosis: An ILUMIEN IV Substudy by Ziad A. Ali, Ulf Landmesser, Akiko Maehara, Doosup Shin, Koshiro Sakai, Mitsuaki Matsumura, Richard A. Shlofmitz, Giuseppe Calligaris, Aziz Maksoud, Youssef S. Abdelwahed, Paolo Canova, Nieves Gonzalo, Fernando Alfonso, Khady N. Fall, Bassem Chehab, Robert J. McGreevy, Robert W. McNutt, Hong Nie, Jin Wang, Jana Buccola, Gregg W. Stone

“…Background The optimal management strategy for in‐stent restenosis (ISR) remains unclear. …”
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Comprehensive Analysis of the Effects of Sacubitril/Valsartan According to Sex Among Patients With Heart Failure and Reduced Ejection Fraction in PARADIGM‐HF by Misato Chimura, Jawad H. Butt, Shingo Matsumoto, Eoghan G. M. McMurray, Alasdair D. Henderson, Atefeh Talebi, Akshay S. Desai, Martin P. Lefkowitz, Adel R. Rizkala, Jean L. Rouleau, Scott D. Solomon, Karl Swedberg, Michael R. Zile, Milton Packer, Pardeep S. Jhund, John J. V. McMurray

“…The primary end point was a composite of cardiovascular death or HF hospitalization. …”
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Association of the comorbidity of gestational diabetes mellitus and hypertension disorders of pregnancy with birth outcomes by Xingxi Lin, Xingxi Lin, Luhan Zhou, Luhan Zhou, Shuting Si, Haoyue Cheng, Haoyue Cheng, Xialidan Alifu, Xialidan Alifu, Yiwen Qiu, Yiwen Qiu, Yan Zhuang, Yan Zhuang, Ye Huang, Ye Huang, Libi Zhang, Libi Zhang, Diliyaer Ainiwan, Diliyaer Ainiwan, Hui Liu, Yunxian Yu, Yunxian Yu

“…BackgroundsMany pregnant women suffer from more than one pregnancy complication. …”
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Clinical Outcome Prediction Model in Tetralogy of Fallot Without Pulmonary Valve Replacement Using Contraction Fraction From the SCOUT‐TOF Registry by Mark A. Fogel, Jennifer A. Faerber, Abdullah Mahmood, Keerthi Reddy, Xuemei Zhang, Elizabeth Goldmuntz, Matthew A. Harris, David Biko, Sara Partington, Stephen Paridon, Michael Mcbride, Victor Ferrari, Kevin K. Whitehead, Laura Mercer‐Rosa

“…Background Few large scale prediction models of clinical outcomes in repaired tetralogy of Fallot (rTOF) exist. …”
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Plasma Polyamines and Short‐Term Adverse Outcomes Among Patients With Ischemic Stroke: A Prospective Cohort Study by Pinni Yang, Mengyao Shi, Yiming Jia, Chongke Zhong, Hao Peng, Lulu Sun, Daoxia Guo, Jing Chen, Aili Wang, Tan Xu, Zhengbao Zhu, Yonghong Zhang, Jiang He

“…Background Polyamines have been reported to be associated with neurological function, but the associations between polyamines and the prognosis of ischemic stroke remain unclear. …”
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Angiographic Quantitative Flow Ratio–Guided Treatment of Patients With Physiologically Intermediate Coronary Lesions by Jiannan Dai, Changdong Guan, Xueming Xu, Jingbo Hou, Haibo Jia, Huai Yu, Zening Jin, Guosheng Fu, Xiaofan Wu, Liansheng Wang, Rongchong Huang, Zhujun Shen, Yanyan Zhao, Yuanzhe Jin, Lei Song, Shengxian Tu, Shubin Qiao, Bo Yu, Bo Xu, Gregg W. Stone

“…Background The FAVOR III (Comparison of Quantitative Flow Ratio Guided and Angiography Guided Percutaneous Intervention in Patients With Coronary Artery Disease) China trial reported improved clinical outcomes with percutaneous coronary intervention guided by quantitative flow ratio (QFR) compared with angiography. …”
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