Identification of Plasma Metabolites Responding to Oxycodone Exposure in Rats by Thao Vu, Suneeta Godbole, Lieselot L. G. Carrette, Lisa Maturin, Olivier George, Laura M. Saba, Katerina Kechris

“…Background: Oxycodone has an elevated abuse liability profile compared to other prescription opioid medications. …”
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Prognostic Implications of Resistive Reserve Ratio in Patients With Nonobstructive Coronary Artery Disease With Myocardial Bridging by Negin Mahmoudi Hamidabad, Yoshihisa Kanaji, Ilke Ozcan, Jaskanwal Deep Singh Sara, Ali Ahmad, Lilach O. Lerman, Amir Lerman

“…Background Myocardial bridging (MB) is accompanied by the dynamic extravascular compression of epicardial coronary arteries, leading to intracoronary hemodynamic disturbance with abnormal coronary flow profiles. …”
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Intrapartum Amnioinfusion for Recurrent Variable Decelerations and Neonatal Morbidity: A Systematic Review and Meta-Analysis by Brock E. Polnaszek, Julia Rossen, Katherine H. Bligard, Angela Hardi, Emily S. Miller, Methodius G. Tuuli, Adam K. Lewkowitz

“…Background: The objective was to estimate the effect of intrapartum amnioinfusion (AI) for recurrent variable decelerations on neonatal morbidity. …”
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Narcolepsy Is Associated With Subclinical Cardiovascular Disease as Early as Childhood: A Big Data Analysis by Christopher N. Kaufmann, Munaza Riaz, Haesuk Park, Wei‐Hsuan Lo‐Ciganic, Debbie Wilson, Emerson M. Wickwire, Atul Malhotra, Rakesh Bhattacharjee

“…Background Narcolepsy is linked to adverse cardiovascular disease (CVD) outcomes, but few studies have examined its associations with subclinical CVD, including in children. …”
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Association Between Neighborhood-Level Social Vulnerability and Hypertension Outcomes by John E. Brush, Jr., MD, Chungsoo Kim, PharmD, PhD, Yuntian Liu, MPH, Xin Xin, MS, Chenxi Huang, PhD, Iris J. Lundy, BSN, Jordan R. Asher, MD, MS, Mitsuaki Sawano, MD, Patrick Young, PhD, Jacob McPadden, MD, Mark Anderson, AS, John S. Burrows, MBA, Harlan M. Krumholz, MD, SM, Yuan Lu, ScD

“…Objectives: The aim of the study was to examine how the neighborhood-level social vulnerability index (SVI) influences cardiovascular outcomes in a large, diverse cohort of patients with hypertension. Methods: We used electronic health data to examine the association between census tract-level rankings for the SVI with a composite endpoint of incident myocardial infarction, congestive heart failure, or stroke. …”
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Change in Dicrotic Notch Index Predicts Outcomes in Patients Undergoing Transcatheter Edge-to-Edge Repair for Mitral Regurgitation by Vishwum Kapadia, Shivabalan Kathavarayan Ramu, MD, Maryam Majeed-Saidan, MD, Rhonda Miyasaka, MD, Serge Harb, MD, Amar Krishnaswamy, MD

“…Background: Changes in the dicrotic notch characteristics in the aortic pressure waveform have not been adequately studied with mitral transcatheter edge-to-edge repair (M-TEER). …”
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Social Vulnerability and Long‐Term Cardiovascular Outcomes After COVID‐19 Hospitalization: An Analysis of the American Heart Association COVID‐19 Registry Linked With Medicare Clai... by Reza Fakhraei, Yang Song, Dhruv S. Kazi, Rishi K. Wadhera, James A. de Lemos, Sandeep R. Das, David A. Morrow, Issa J. Dahabreh, Christine M. Rutan, Kathie Thomas, Robert W. Yeh

“…Background Patients hospitalized with COVID‐19 from socioeconomically vulnerable communities are at risk for in‐hospital cardiovascular events. …”
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Myocardial Work in Children With Hypertrophic Cardiomyopathy by Xander Jacquemyn, BSc, Rebbeca Dryer, MD, Kyla Cordrey, MD, Rita Long, RDCS, David A. Danford, MD, MPH, Shelby Kutty, MD, PhD, MHCM, Benjamin T. Barnes, MD

“…Background: Myocardial work (MW) predicts adverse outcomes in adults with hypertrophic cardiomyopathy (HCM), yet pediatric data are lacking. …”
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Early detection to improve outcome in people with undiagnosed psoriatic arthritis: the PROMPT research programme including RCT by Neil McHugh, Laura Bojke, Mel Brooke Turfrey, Rachel Charlton, Myka Ransom, Laura C Coates, Howard Collier, Claire Davies, Emma Dures, Philip Helliwell, Jana James, Anya Lissina, Vishnu B Madhok, Alison L Nightingale, Jonathan Packham, Catherine Smith, Eldon Spackman, Cerys Tassinari, William Tillett, Sarah T Brown

“…Background Longitudinal observational studies suggest that patients who present early to secondary care with psoriatic arthritis have a better outcome. …”
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Social Determinants of Health and Cardiovascular Risk among Adults with Diabetes: The Reasons for Geographic and Racial Differences in Stroke (REGARDS) Study by Lisa Zhang, Evgeniya Reshetnyak, Joanna B. Ringel, Laura C. Pinheiro, April Carson, Doyle M. Cummings, Raegan W. Durant, Gargya Malla, Monika M. Safford

“…Background Social determinants of health (SDOH) have been associated with diabetes risk; however, their association with cardiovascular disease (CVD) events in individuals with diabetes is poorly described. …”
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Real-Time ConvNext-Based U-Net with Feature Infusion for Egg Microcrack Detection by Chenbo Shi, Yuejia Li, Xin Jiang, Wenxin Sun, Changsheng Zhu, Yuanzheng Mo, Shaojia Yan, Chun Zhang

“…Furthermore, on the publicly benchmarked CrackSeg9k dataset, CBU-FI Net achieves an inference speed of 4 ms for 400 × 400 resolution images, with an MIoU of 81.38%, proving the proposed method’s robustness and generalization capability across various cracks and complex backgrounds.…”
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Association Between Caregiver Strain and Self‐Care Among Caregivers With Hypertension: Findings From the REGARDS Study by Asia Gobourne, Joanna Bryan Ringel, Alexandra King, Monika Safford, Catherine Riffin, Ronal Adelman, Adam Bress, Tracy K. Paul, Raegan W. Durant, David L. Roth, Madeline R. Sterling

“…Background Self‐care for adults with hypertension includes adherence to lifestyle behaviors and medication. …”
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Predicting the incidence of depression in adolescence using a sociodemographic risk score: prospective follow-up of the IDEA-RiSCo study by Christian Kieling, Brandon A Kohrt, Anna Viduani, Valeria Mondelli, Helen L Fisher, Jader Piccin, Claudia Buchweitz, Pedro H Manfro, Rivka Barros Pereira, Fernanda Rohrsetzer, Laila Souza, Arthur Caye, Johnna R Swartz

“…Background Adolescence constitutes a critical window for preventing depression, but efforts have mostly targeted single risk factors. …”
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Rationale and Design of the ORCCA (Outcomes Registry for Cardiac Conditions in Athletes) Study by Nathaniel Moulson, Bradley J. Petek, Michael J. Ackerman, Timothy W. Churchill, Sharlene M. Day, Jonathan H. Kim, Stephanie A. Kliethermes, Rachel Lampert, Benjamin D. Levine, Matthew W. Martinez, Manesh R. Patel, Dermot Phelan, Kimberly G. Harmon, Aaron L. Baggish, Jonathan A. Drezner

“…Background Clinical practice recommendations for participation in sports and exercise among young competitive athletes with cardiovascular conditions at risk for sudden death are based largely on expert consensus with a paucity of prospective outcomes data. …”
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Sex Differences in the Association Between Lipoprotein(a) and Cardiovascular Outcomes: The MGB Lp(a) Registry by Gurleen Kaur, Adam N. Berman, David W. Biery, Stephanie A. Besser, Wanda Y. Wu, Brittany Weber, Michael C. Honigberg, Khurram Nasir, Martha Gulati, Marcelo F. Di Carli, Leslee J. Shaw, Deepak L. Bhatt, Ron Blankstein

“…Background Sex‐based differences in the association of lipoprotein(a) with cardiovascular outcomes have not been well established for those without prior atherosclerotic cardiovascular disease. …”
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Construct and Predictive Validity of the Kansas City Cardiomyopathy Questionnaire in Adult Congenital Heart Disease by Ryan D. Byrne, MD, Ajith P. Nair, MD, Stephen J. Dolgner, MD, Swati Choudhry, MD, Edward J. Hickey, MD, Alexis C. Wood, PhD, Savitri Fedson, MD, Biykem Bozkurt, MD, PhD, Christopher R. Broda, MD

“…Background: The Kansas City Cardiomyopathy Questionnaire (KCCQ) is an Food and Drug Administration-approved health status measure for patients with heart failure (HF) but has not been directly assessed in adult congenital heart disease (ACHD). …”
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Associations Between Social Determinants of Health, Allostatic Load, and Anthracycline Cardiotoxicity in a Diverse Patient Population by Lili Zhang, Justin Song, Waqas Hanif, Rachel Clark, Magued Haroun, Mrunalini Dandamudi, Patricia Guia Simoza, Leandro Slipczuk, Mario J. Garcia, Min Pu, Carlos A. Gongora, Tomas G. Neilan, Della F. Makower, Earle C. Chambers, Carlos J. Rodriguez

“…Background Allostatic load (AL) is a measurement of physiological burden of chronic stress, operationalized using a composite score derived from biomarkers from multiple physiologic systems. …”
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Sex and race disparities in emergency department patients with chest pain and a detectable or mildly elevated troponin by Lucas M. Boyer, Anna C. Snavely, Jason P. Stopyra, Subha V. Raman, Jeffrey M. Caterino, Carol L. Clark, Alan E. Jones, Michael E. Hall, Carolyn J. Park, Brian C. Hiestand, Sujethra Vasu, Michael A. Kutcher, W. Gregory Hundley, Simon A. Mahler, Chadwick D. Miller

“…Background: Identifying and eliminating health disparities is a public health priority. …”
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Analysis of retirees' knowledge return in the supply chain of Isfahan Refinery with a combined approach of interpretive structural modeling and structural equation modeling by Mehran Ziaeian, Somayeh Ahmadzadeh, Abdolrasoul Yazdi

“…Initially, 12 factors affecting the return of retirees' knowledge were identified based on a literature review and research background and were approved by academic and industrial experts (Isfahan Refinery). …”
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Total and Structural Carotid Artery Stiffness Are Associated With Cognitive Decline and Structural Brain Abnormalities Related to Alzheimer Disease and Alzheimer Disease‐Related De... by Jeremy R. Williams, Theodore M. DeConne, Ryan Pewowaruk, Claudia Korcarz, Jordan Tanley, Cynthia Carlsson, Susan R. Heckbert, Mohamad Habes, Ilya Nasrallah, Samuel N. Lockhart, José A. Luchsinger, Jingzhong Ding, Kathleen M. Hayden, Timothy M. Hughes, Adam D. Gepner

“…Background Arterial stiffness is associated with pathological changes underlying Alzheimer disease and related dementias. …”
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