An Overview of Patient-reported Outcomes for Men with Prostate Cancer: Results from the PIONEER Consortium by Sebastiaan Remmers, Katharina Beyer, Tariq A. Lalmahomed, Peter Prinsen, Nicole J.E. Horevoorts, Nora Tabea Sibert, Christoph Kowalski, Francesco Barletta, Oliver Brunckhorst, Giorgio Gandaglia, Jochem R.N. van der Voort van Zyp, Emma J. Smith, Andre Deschamps, Laurence Collette, Philip Cornford, Susan Evans-Axelsson, James N’Dow, Mieke Van Hemelrijck, Monique J. Roobol, Lionne D.F. Venderbos

“…Using prospectively collected data from the Prostate Cancer Diagnosis and Treatment Enhancement Through the Power of Big Data in Europe (PIONEER) consortium, we aimed to describe the functional status and QoL in men with prostate cancer (PCa) treated with active surveillance (AS), radical prostatectomy (RP), and radiotherapy (RT), and to demonstrate the applicability of PROM data on a large scale and at a European level. Methods: We identified data sources that collected QoL data using the European Organization for Research and Treatment of Cancer (EORTC) QLQ-C30, EORTC QLQ-PR25, or Expanded Prostate Cancer Index Composite (EPIC)-26/50 questionnaires. …”
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Exposure to diverse airborne bacterial communities following Klebsiella pneumoniae infection elicits distinct host response mechanisms in mice by Chenchen Song, Li Zhou, Lianlian Zhao, Zhi Guo, Lifang Zhang, Hu Yang, Yuhan Lei, Yunlin Han, Yanfeng Xu, Zhiguang Xiang, Baicun Li, Jianguo Guo

“…Method: We randomly generated five distinct bacterial communities with varying compositions from a pool of 16 bacteria. …”
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Multiparametric cardiovascular magnetic resonance is associated with outcomes in pediatric heart transplant recipients by Andrew A. Lawson, Kae Watanabe, Lindsay Griffin, Christina Laternser, Michael Markl, Cynthia K. Rigsby, Joshua D. Robinson, Nazia Husain

“…ABSTRACT: Background: Multiparametric cardiovascular magnetic resonance (CMR) has an emerging role in non-invasive surveillance of pediatric heart transplant recipients (PHTR). …”
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Associations between nighttime or weekend deliveries and adverse maternal, birth, and neonatal outcomes: secondary analysis of the MANGO study in western Kenya by Maneet K. Virk, Jenine Shafi, Pooja Maheria, Garoma Basha, Harold E. Kooreman, John Humphrey, James G. Carlucci, Audrey Chepkemoi, Caitlin Bernard, Megan S. McHenry, Beverly Musick, Caroline Kerich, Winnie Matelong, Constantin T. Yiannoutsos, Wycliffe Kosgei, Julia Songok, Kara Wools-Kaloustian, Edwin Were, Rena C. Patel

“…Abstract Background Maternal and neonatal morbidity and mortality remain high in low-income and middle- income countries (LMICs), and staffing schedules may contribute to adverse pregnancy outcomes. …”
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Technological dental sealants: in vitro evaluation of material properties and antibiofilm potential by Witalo Pereira de Jesus, Luiza de Almeida Queiroz Ferreira, Washington Henrique Themoteo da Silva, Fernanda Vieira Belém, Ana Paula Turrioni, Cláudia Silami de Magalhães, Mila Fernandes Moreira Madeira, Ivana Márcia Alves Diniz, Marco Aurelio Benini Paschoal

“…Abstract Background Due to the launch of new self-etching and self-adhesive sealing materials combined with the release of bioactive ions in the dental market, this in vitro study aimed to compare physical values of surface roughness (RS), vickers microhardness (VM), compositional energy dispersive spectroscopy (EDS), scanning electron microscopy (SEM), microbiological tests (inhibition halo-HI and surface microbial adhesion-MAS) and mechanical microshear bond strength (MBS). …”
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The Role of Glycemic Control in Inflammation Markers and Clinical Outcomes in Type 2 Diabetes Patients with Severe COVID-19 by Lavinia Craciun, Flavia Ignuta, Uma Shailendri Rayudu, Maliha Afra, Ovidiu Rosca, Adrian Vlad, Oana Aburel, Dana Emilia Velimirovici

“…<b>Background and Objectives:</b> Patients with type 2 diabetes mellitus (T2DM) are at a heightened risk of adverse outcomes from Coronavirus Disease 2019 (COVID-19). …”
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Prognostic implication of outpatient loop diuretic dose intensification trajectories in patients with chronic heart failure by Toshiharu Koike, Atsushi Suzuki, Noriko Kikuchi, Asami Yoshimura, Kaoru Haruki, Ayano Yoshida, Maiko Sone, Mayui Nakazawa, Kei Tsukamoto, Yasutaka Imamura, Hidetoshi Hattori, Tomohito Kogure, Junichi Yamaguchi, Tsuyoshi Shiga

“…Background: The relationship between outpatient oral loop diuretic (OLD) dose intensification trajectories and the prognosis of patients with chronic heart failure (CHF) remains unclear. …”
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Hypomethylating agents plus venetoclax for high-risk MDS and CMML as bridge therapy to transplant: a GESMD study by Ines Zugasti, Monica Lopez-Guerra, Sandra Castaño-Díez, Daniel Esteban, Alejandro Avendaño, Helena Pomares, Ana Perez, Sara García-Ávila, Irene Padilla Conejo, Cristina de la Fuente Montes, Alexandra Martínez-Roca, Beatriz Merchán, Carlos Jiménez-Vicente, Francesca Guijarro, Jose Ramón Álamo, Albert Cortes-Bullich, Victor Torrecillas, Lucia Mont, Esther Carcelero, Gisela Riu, Lurdes Zamora, Joan Bargay, Ana Triguero, Maria Suarez-Lledó, Maria Queralt Salas, Felix López-Cadenas, Fernando Ramos, Blanca Xicoy, David Valcárcel, Montserrat Arnan, Carmen Martínez, Montserrat Rovira, Francesc Fernández-Avilés, Maria Díez-Campelo, Jordi Esteve, Marina Díaz-Beyá

“…Abstract Background High-risk myelodysplastic syndromes (HR-MDS) and chronic myelomonocytic leukemia (CMML) remain therapeutic challenges with suboptimal outcomes. …”
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Multi‐Trait Polygenic Risk Score, Nongenetic Determinants, and Cardiovascular Disease Death: A Cohort Study of 14 086 Japanese Individuals by Ryosuke Fujii, Mako Nagayoshi, Masahiro Nakatochi, Shuntaro Sato, Yoshiki Tsuboi, Koji Suzuki, Hiroaki Ikezaki, Yuichiro Nishida, Yoko Kubo, Shiroh Tanoue, Sadao Suzuki, Teruhide Koyama, Kiyonori Kuriki, Naoyuki Takashima, Sakurako Katsuura‐Kamano, Yukihide Momozawa, Kenji Wakai, Keitaro Matsuo

“…Background Although utility of composite trait‐specific polygenic risk score (multi‐trait PRS) has been examined among European ancestries, few studies investigated among East Asians and incorporated modifiable risk factors. …”
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Association of habitual glucosamine use with risk of microvascular complications among individuals with type 2 diabetes: a prospective cohort study in UK biobank by Zi-Jian Cheng, Yu-feng Luo, Qing-yun Zhu, Yan-fei Wang, Wen-yan Ren, Fei-yan Deng, Lin Bo, Xi-Yuan Jiang, Shu-feng Lei, Long-Fei Wu

“…Abstract Background Glucosamine is a widely used supplement for treating osteoarthritis and joint pain. …”
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Impact of Procedural Success Definitions on Long‐Term Outcomes in Patients With Rheumatic Mitral Stenosis Treated With Percutaneous Balloon Mitral Valvuloplasty: A Multicenter, Ret... by Premanan Manoret, Tasalak Thonghong, Krissada Meemook, Seththawut Kosallavat, Suchart Aroonsiriwattana, Thammarak Songsangjinda, Saranyou Suwanugsorn, Thanapon Nilmoje, Sirichai Cheewatanakornkul, Treechada Wisaratapong, Sunti Limumpornpetch, Watchara Lohawijarn, Metus Thungthienthong, Noppadol Chamnarnphol, Mann Chandavimol, Pannipa Suwannasom, Woravut Jintapakorn, Ply Chichareon

“…Background It is uncertain which percutaneous balloon mitral valvuloplasty (PBMV) success definitions should be used because there are no studies comparing the effects of these definitions on subsequent outcomes. …”
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3D-CT-derived lung volumes and mortality risk in patients with fibrotic hypersensitivity pneumonitis by Shusuke Yazawa, Yuzo Suzuki, Yuko Tanaka, Koshi Yokomura, Masato Kono, Dai Hashimoto, Atsuki Fukada, Yusuke Inoue, Hideki Yasui, Hironao Hozumi, Masato Karayama, Kazuki Furuhashi, Noriyuki Enomoto, Tomoyuki Fujisawa, Naoki Inui, Takafumi Suda

“…Background: Hypersensitivity pneumonitis (HP) is a complex and heterogenous interstitial lung disease (ILD) that occurs in susceptible individuals due to certain inhaled antigens. …”
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Genotypic and Phenotypic Association of Agronomic Features in Triticale Genotypes under Drought Stress Conditions by Hassan Basiri, Omid Alizadeh, Forud Bazrafshan, Mehdi Zare, Mohammad Yazdani

“…Extended Abstract Background: Many efforts have been made to combine the diverse capabilities of different plant species into a unique plant to increase the quantity and quality of the food product. …”
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Direct Oral Anticoagulants Versus Vitamin K Antagonists After Mitral Valve Transcatheter Edge‐to‐Edge Repair in Patients With Atrial Fibrillation: A Single‐Center Observational Stu... by Jan‐Hendrik Schipper, Anne‐Sophie Sommer, Richard Julius Nies, Clemens Metze, Max Maria Meertens, Jonas Wörmann, Sebastian Dittrich, Jan‐Hendrik van den Bruck, Arian Sultan, Jakob Lüker, Daniel Steven, Christopher Hohmann, Roman Pfister, Stephan Baldus, Ingo Eitel, Christian Frerker, Tobias Schmidt

“…Background Mitral valve transcatheter edge‐to‐edge repair (M‐TEER) has emerged as a viable therapy option in patients with severe mitral regurgitation and high surgical risk. …”
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Optimal Medical Therapy for Heart Failure and Integrated Care in Patients With Atrial Fibrillation: A Report From the ESC‐EHRA EORP Atrial Fibrillation Long‐Term General Registry... by Niccolò Bonini, Marco Proietti, Giulio Francesco Romiti, Marco Vitolo, Ameenathul Mazaya Fawzy, Wern Yew Ding, Jacopo Francesco Imberti, Laurent Fauchier, Francisco Marin, Michael Nabauer, Gheorghe Andrei Dan, Tatjana S. Potpara, Giuseppe Boriani, Gregory Y. H. Lip

“…Background Heart failure (HF) often occurs in patients with atrial fibrillation (AF), with a major impact on prognosis. …”
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Integrated machine learning and population attributable fraction analysis of systemic inflammatory indices for mortality risk prediction in diabetes and prediabetes by Zixi Zhang, Chenyang Li, Yichao Xiao, Chan Liu, Xiaoqin Luo, Cancan Wang, Yongguo Dai, Qiuzhen Lin, Zeying Zhang, Cheng Zheng, Jiafeng Lin, Tao Tu, Qiming Liu

“…Background Chronic systemic inflammation is a key contributor to cardiometabolic complications in diabetes mellitus (DM) and prediabetes (PreDM). …”
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Assessing the Fortification Quality of Refined Vegetable Oil with Vitamin A, Wheat Flour with Iron, and Salt with Iodine: Findings from a Market Assessment in Senegal, West Africa by Mane Hélène Faye, Marie-Madeleine A Diémé, Phillip M Nkhoma, Adama Diouf, Dora Panagides, Abdou Badiane, Becky L Tsang, Olouwafemi Mistourath Mama, Marielle A De Souza, Nicole Idohou Dossou

“…Background: Mandatory fortification (MF) of wheat flour (WF) with iron/folic acid, refined edible oil with vitamin A (VA), and salt with iodine is implemented to address micronutrient deficiencies in Senegal. …”
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Stratifying risk outcomes among adult COVID-19 inpatients with high flow oxygen: The R4 score by G.M. Aguirre-García, D. Ramonfaur, G. Torre-Amione, M.T. Ramírez-Elizondo, R. Lara-Medrano, J.F. Moreno-Hoyos, E.S. Velázquez-Ávila, C.A. Diaz-Garza, V.M. Sanchez-Nava, F. Castilleja-Leal, G.M. Rhoades, M.F. Martínez-Reséndez

“…This study aims to provide a simple risk stratification system to predict invasive mechanical ventilation (IMV) or death among COVID-19 inpatients on HFO.Methods Among 529 adult inpatients with COVID-19 pneumonia, we selected unadjusted clinical risk factors for developing the composite endpoint of IMV or death. …”
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Efficacy and safety of direct oral anticoagulants compared with warfarin in antiphospholipid syndrome. Results of a multicenter retrospective cohort study by Maha A.T. Elsebaie, Zoe Wickham, Stephanie DeBragga, Stacey Fedewa, Mohamed Amgad, Jane Jungyoon Park, Allen Li, Ali Eshaghpour, Juan Li, Mark Crowther, Manila Gaddh

“…Background: Direct oral anticoagulants (DOACs) have become firstline treatment for many thrombotic conditions, but their use in antiphospholipid syndrome (APS) patients remains controversial. …”
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Sodium–glucose cotransporter-2 inhibitors improve cardiovascular outcomes post-acute coronary syndrome complicated by acute heart failure by Alaa Rahhal, Tahseen Hamamyh, Ammar Chapra, Khaled J. Zaza, Mostafa Najim, Mohammad Hemadneh, Hazem Faraj, Wael Kanjo, Ahmed Yasin, Haneen Toba, Wafa Mohammed, Mohammad Khair Hamad, Nawras Al-Tikrety, Mhd Baraa Habib, Ahmed Awaisu, Ahmed Mahfouz, Sumaya Alyafei, Abdul Rahman Arabi, Ashfaq Patel, Mohammed Al-Hijji, Mohammed Al-Hijji

“…BackgroundAcute coronary syndrome (ACS) remains a risk factor for heart failure (HF). …”
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