Biotechnology Production of Cell Biomass from the Endangered <i>Kickxia elatine</i> (L.) Dumort: Its Untargeted Metabolomic Analysis and Cytotoxic Potential Against Melanoma Cells by Anastasia Aliesa Hermosaningtyas, Ewa Totoń, Anna Budzianowska, Natalia Lisiak, Aleksandra Romaniuk-Drapała, Dariusz Kruszka, Monika Rewers, Małgorzata Kikowska

“…<b>Background:</b> Melanoma is a malignant tumor of melanocytes with an increasing incidence worldwide. …”
Get full text

Printable biomaterials for 3D brain regenerative scaffolds: An in vivo biocompatibility assessment by Maylis Combeau, Nina Colitti, Julien Clauzel, Franck Desmoulin, Adrien Brilhault, Juliette Fitremann, Mickaël Chabbert, Matthew L. Becker, Sébastien Blanquer, Lorenne Robert, Melissa Parny, Isabelle Raymond-Letron, Carla Cirillo, Isabelle Loubinoux

“…Developments in 3D printing offer the possibility of designing complex structures of varying compositions adapted to tissue anatomy. Methods: This feasibility study assessed the cerebral biocompatibility of four bioeliminable Digital Light Processing (DLP) printed materials in the rat model: gelatin methacrylate (GelMA), poly(ethylene glycol)diacrylate (PEGDA) mixed with GelMA (PEGDA-GelMA), poly(trimethylene carbonate) trimethacrylate (PTMC-tMA) and an ABA triblock copolymer of polypropylene fumarate-b-poly γ-methyl ε-caprolactone-b-polypropylene fumarate (P(PF-MCL-PF)). …”
Get full text

Outpatient acute kidney disease detection by national and institutional health data by Hsiu-Yin Chiang, Hung-Chieh Yeh, Zi-Han Lin, Bradley Chen, David Ray Chang, I-Wen Ting, Jie-Sian Wang, Yun-Lun Chang, Hung-Lin Chen, Yu-Chih Liu, Mei-Chuan Hsieh, Tzu-Ling Karen Tzeng, Chin-Chi Kuo

“…Abstract Background The development of diagnostic definitions for acute kidney disease in outpatients (AKDOPT) remains an unattained goal because of consensus gaps and data silos in health-care systems. …”
Get full text

Association of suicidal behavior with exposure to suicide and suicide attempt: A systematic review and multilevel meta-analysis. by Nicole T M Hill, Jo Robinson, Jane Pirkis, Karl Andriessen, Karolina Krysinska, Amber Payne, Alexandra Boland, Alison Clarke, Allison Milner, Katrina Witt, Stephan Krohn, Amit Lampit

“…<h4>Background</h4>Exposure to suicidal behavior may be associated with increased risk of suicide, suicide attempt, and suicidal ideation and is a significant public health problem. …”
Get full text

The triglyceride-glucose index, a marker of insulin resistance, as a predictor of thrombotic risk in atrial fibrillation by José Miguel Rivera-Caravaca, Eva Soler-Espejo, María Pilar Ramos-Bratos, Raquel López-Gálvez, Eduardo González-Lozano, Gregory Y. H. Lip, Francisco Marín, Vanessa Roldán

“…Abstract Background Atrial fibrillation (AF) increases the risk of stroke making accurate risk stratification central for effective management. …”
Get full text

Relationship between cognitive impairments and psychopathological symptoms in female schizophrenia subsequent to 8 weeks treatment with antipsychotic drugs by Shuzhan Gao, Qing Xu, Yanlin Han, Jing Jiang, Fan Wu, Ting Peng, Chenxi Ling, Sulin Ni, Rongrong Zhang, Yidan Ming, Xuzhen Liu, Xijia Xu

“…Abstract Background Changes in cognitive impairments and their relationship with psychopathological symptoms during treatment in schizophrenia remain debatable. …”
Get full text

Remnant–to–LDL cholesterol discordance as a predictor of thromboembolic events in anticoagulated patients with atrial fibrillation: a report from the prospective Murcia AF project... by Eva Soler-Espejo, Yang Chen, José Miguel Rivera-Caravaca, María Pilar Ramos-Bratos, Raquel López-Gálvez, Francisco Marín, Vanessa Roldán, Gregory Y.H. Lip

“…Abstract Background Remnant cholesterol (RC) has emerged as an independent contributor to residual cardiovascular risk, beyond low-density lipoprotein cholesterol (LDL-C). …”
Get full text

Initial Clinical Experience with the Biodegradable AbsnowTM Device for Percutaneous Closure of Atrial Septal Defect: A 3-Year Follow-Up by Yifan Li, Yumei Xie, Boning Li, Zhaofeng Xie, Junjun Shen, Shushui Wang, Zhiwei Zhang

“…Methods. Five pediatric patients were enrolled from May to June 2018 in our institution and were followed up for 3 years. …”
Get full text

Immune profiling of the macroenvironment in colorectal cancer unveils systemic dysfunction and plasticity of immune cells by Haoxian Ke, Peisi Li, Zhihao Li, Xian Zeng, Chi Zhang, Shuzhen Luo, Xiaofang Chen, Xinlan Zhou, Shichen Dong, Shaopeng Chen, Junfeng Huang, Ming Yuan, Runfeng Yu, Shubiao Ye, Tuo Hu, Zhonghui Tang, Dongbin Liu, Kui Wu, Xianrui Wu, Ping Lan

“…Abstract Background Tumour immune macroenvironment is comprised of tumour and surrounding organs responding to tumourigenesis and immunotherapy. …”
Get full text

Sex differences in the prevalence and survival of pulmonary hypertension in obstructive hypertrophic cardiomyopathy following septal myectomy by Changrong Nie, Yifeng Zhu, Minghu Xiao, Changsheng Zhu, Yanhai Meng, Zhengyang Lu, Qiulan Yang, Shuiyun Wang

“…Background: Pulmonary hypertension (PH) and female have been linked to a worse survival in patients with obstructive hypertrophic cardiomyopathy (oHCM). …”
Get full text

Association between gestational weight gain and severe adverse birth outcomes in Washington State, US: A population-based retrospective cohort study, 2004-2013. by U Vivian Ukah, Hamideh Bayrampour, Yasser Sabr, Neda Razaz, Wee-Shian Chan, Kenneth I Lim, Sarka Lisonkova

“…<h4>Background</h4>Suboptimal weight gain during pregnancy is a potentially modifiable risk factor. …”
Get full text

Efficacy of a Blended Low-Intensity Internet-Delivered Psychological Program in Patients With Multimorbidity in Primary Care: Randomized Controlled Trial by Alicia Monreal-Bartolomé, Adoración Castro, M Ángeles Pérez-Ara, Margalida Gili, Fermín Mayoral, María Magdalena Hurtado, Esperanza Varela Moreno, Cristina Botella, Azucena García-Palacios, Rosa M Baños, Yolanda López-Del-Hoyo, Javier García-Campayo, Jesus Montero-Marin

“… BackgroundMultimorbidity is a highly prevalent phenomenon whose presence causes a profound physical, psychological, and economic impact. …”
Get full text

Dental Students’ Perception and Self-Perceived Confidence Level in Key Dental Procedures for General Practice and the Impact of Competency Implementation on Their Confidence Level,... by Wijdan R. Elmanaseer, Salah A. Al-Omoush, Rasha A. Alamoush, Rawan Abu Zaghlan, Firas Alsoleihat

“…Background. Evaluating the level of dental students’ competence is crucial for validating their preparedness for graduation. …”
Get full text

Enhancing retention and quality of tissue stromal vascular fraction graft with globo H ceramide by Jing-Yan Cheng, Hui-Yun Cheng, Jung-Tung Hung, Gonzalo Mallarino Restrepo, Shih-Pin Chiou, Ling-Yi Shih, Alice L. Yu, Huang-Kai Kao, John Yu, Fu-Chan Wei

Get full text

Parental and Demographic Predictors of Engagement in an mHealth Intervention: Observational Study From the Let’s Grow Trial by Johanna Sandborg, Brittany Reese Markides, Savannah Simmons, Katherine L Downing, Jan M Nicholson, Liliana Orellana, Harriet Koorts, Valerie Carson, Jo Salmon, Kylie D Hesketh

“… BackgroundParents are integral in shaping early childhood health behaviors, and mobile health (mHealth) interventions offer an accessible method of supporting them in this role. …”
Get full text

Impact of antihypertensive drug classes on cardiovascular outcomes: insights from the STEP study by Xinyi Peng, Michael Hecht Olsen, Manan Pareek, Jingjing Bai, Yang Liu, Qirui Song, Jun Cai

“…Abstract Background The optimal class of antihypertensive drugs for reducing cardiovascular risk remains unclear. …”
Get full text

Relationship Among Macronutrients, Dietary Components, and Objective Sleep Variables Measured by Smartphone Apps: Real-World Cross-Sectional Study by Jaehoon Seol, Masao Iwagami, Megane Christiane Tawylum Kayamare, Masashi Yanagisawa

“… BackgroundFew studies have explored the relationship between macronutrient intake and sleep outcomes using daily data from mobile apps. …”
Get full text

Dynamic Lipid–Glycaemic Index and Inflammation—Endothelial Shifts and Fetal Aortic Wall Thickening: A Repeated-Measures Gestational Phenotyping Study by Maria Cezara Muresan, Biliana Belovan, Ioan Sîrbu, Zoran Laurentiu Popa, Cosmin Citu, Ioan Sas, Adrian Ratiu

“…<i>Background and Objectives</i>: Maternal dyslipidaemia and low-grade inflammation are recognised drivers of in utero vascular remodelling, yet composite dynamic markers that integrate lipid–glycaemic, inflammatory and endothelial signals have not been evaluated. …”
Get full text

Thyroid Feedback Quantile-based Index correlates strongly to renal function in euthyroid individuals by Sijue Yang, Shuiqing Lai, Zixiao Wang, Aihua Liu, Wei Wang, Haixia Guan

“…Background Previous studies have reported a negative relationship between thyroid-stimulating hormone (TSH) and renal function in euthyroid individuals, but others have found that higher free thyroxine (FT4) was associated with an increased risk of chronic kidney disease. …”
Get full text

Obstructive sleep apnea syndrome in polycystic ovary syndrome: a systematic review and meta-analysis by Nur K. Abdul Jafar, Afra Al Balushi, Anuradhaa Subramanian, Siang Ing Lee, Christie J. Bennett, Lisa J. Moran, Aya Mousa, Chau Thien Tay, Helena J. Teede, Darren R. Mansfield

“…BackgroundPolycystic ovary syndrome (PCOS) has been associated with a high prevalence of obstructive sleep apnea syndrome (OSAS). …”
Get full text