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1921
Gut Microbiome Alteration in HIV/AIDS and the Role of Antiretroviral Therapy—A Scoping Review
Published 2024-11-01“…(1) Background: The gut microbiota plays a crucial role in chronic immune activation associated with human immunodeficiency virus (HIV) infection, acquired immune deficiency syndrome (AIDS) pathogenesis, non-AIDS-related comorbidities, and mortality among people living with HIV (PLWH). …”
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1922
Exploring a role for Chemerin in the cardiovascular and musculoskeletal benefits of intradialytic exercise in the hemodialysis population.
Published 2025-01-01“…<h4>Background</h4>Cardiovascular disease is the leading cause of death for people receiving hemodialysis. …”
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1923
Assessment of Practices on Purchase of Packaged Foods and Utilization Patterns of Food Labels among Adults in Puducherry
Published 2025-05-01“…Background: There is an increase in the manufacture and consumption of prepackaged foods as a result of widespread urbanization, long working time, and adaption to a sedentary lifestyle. …”
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1924
Saliva-Based Biomarkers in Oral Squamous Cell Carcinoma Using OMICS Technologies: A Systematic Review
Published 2024-07-01“…This study reviews omics technologies to assess new salivary biomarkers for the early detection of OSCC. (2) Methods: A comprehensive literature search in the last 20 years identified four relevant studies focusing on salivary biomarkers in OSCC. (3) Results: Proteomic and genomic analyses revealed significant changes in salivary composition between OSCC patients and healthy controls, suggesting promising diagnostic and prognostic biomarkers. …”
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1925
Preliminary investigation of gut microbiota and associated metabolic pathways in the pathogenesis of primary central nervous system lymphoma
Published 2025-04-01“…BackgroundPrimary central nervous system lymphoma (PCNSL) is a rare and highly aggressive form of non-Hodgkin lymphoma, primarily confined to the central nervous system. …”
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1926
Tripartite interplay: immune reconstitution dynamics in AIDS, gut microbiota, and Helicobacter pylori infection: current advances and therapeutic prospects
Published 2025-07-01“…Abstract Background The immune recovery process in Acquired Immune Deficiency Syndrome (AIDS) is complex and influenced by numerous factors. …”
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1927
Assessment of Solid Waste Management Practices in Kabowohe Division, Sheema Muinicipal Council, Sheema District
Published 2023“…Currently, this approach has proven to be inefficient due to the heavy financial requirements involved. Background: Kabwohe Division generates 20,580 metric tons of solid waste annually, of which only 17,215 metric tons (59.6%) are collected annually. …”
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1928
Expert panel as reference standard procedure in diagnostic accuracy studies: a systematic scoping review and methodological guidance
Published 2025-05-01“…Abstract Background In diagnostic accuracy studies, when no reference standard test is available, a group of experts, combined in an expert panel, is often used to assess the presence of the target condition using multiple relevant pieces of patient information. …”
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1929
A Comprehensive Quality Evaluation System for Medicinal Leeches by Integrating Macromolecular Protein Analysis and Small-Molecule Marker Detection as Well as Quantitative Bioassays
Published 2025-06-01“…<b>Methods:</b> In this study, an integrated quality evaluation strategy guided by “Totality of the Evidence” (TOE) method is proposed. …”
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1930
Software-Based Transformation of White Light Endoscopy Images to Hyperspectral Images for Improved Gastrointestinal Disease Detection
Published 2025-06-01“…<b>Background/Objectives:</b> Gastrointestinal diseases (GID), such as oesophagitis, polyps, and ulcerative colitis, contribute significantly to global morbidity and mortality. …”
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1931
C-Reactive Protein-to-Serum Chloride Ratio: A Novel Marker of All-Cause Mortality in Maintenance Haemodialysis Patients
Published 2024-10-01“…Some studies suggest the influence of inflammation as a synergistic factor, so we set out to analyse the association of a novel C-reactive protein-to-serum chloride ratio (CRP/Cl<sup>−</sup>) with the prognosis of maintenance haemodialysis patients and to assess its relationship with fluid status and body composition measured by bioimpedance. <i>Materials and Methods</i>: the present work is a retrospective cohort study of maintenance haemodialysis patients from our chronic outpatient haemodialysis programme between 1 January 2022 and 31 December 2022. …”
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1932
Anti-Gastric Cancer Activity of Mixed-Region Iranian Propolis Nanoparticles: Potential Therapeutic Applications
Published 2025-01-01“…Background: Propolis holds great potential in therapeutic development due to the presence of flavonoids, phenolic acids, and esters. …”
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1933
Anti-Infection Efficacy, Osteogenesis Potential, and Biocompatibility of 3D Printed PLGA/Nano-Hydroxyapatite Porous Scaffolds Grafted with Vancomycin/DOPA/rhBMP-2 in Infected Rabbi...
Published 2025-05-01“…Through the three-dimensional (3D) printing technology, we fabricated a poly(lactic-co-glycolic acid)(PLGA)/nano-hydroxyapatite (n-HA) composite scaffold grafted with the antibiotic vancomycin and loaded with the osteoinductive agent recombinant human bone morphogenic protein-2 (rhBMP-2) via polydopamine (DOPA) chemistry, whose therapeutic effects on IBD were determined.Methods: After examining the hydrophilicity, surface chemical composition, mechanical properties, and drug release of the PLGA/n-HA, PLGA/n-HA/VAN, and PLGA/n-HA/VAN+DOPA/rhBMP-2 composite scaffolds, pre-osteoblast MC3T3-E1 cells were seeded onto the scaffold surface to assess the biocompatibility and osteoconductive properties of the scaffolds in vitro. …”
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1934
Application of single venous approach under echocardiography without angiography in closure of Patent Ductus Arteriosus
Published 2024-12-01“…Abstract Background The conventional arteriovenous approach closure of patent ductus arteriosus (PDA) may be associated with more complications, especially in young infants. …”
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1935
Phytochemical profiling and in silico evaluation of Artemisia absinthium compounds targeting Leishmania N-myristoyltransferase: molecular docking, drug-likeness, and toxicity analy...
Published 2024-11-01“…The bioactive compounds in A. absinthium could potentially inhibit NMT and serve as new treatment options for leishmaniasis.AimThis study aims to investigate the phytochemical composition, drug-likeness, and molecular dynamics of A. absinthium bioactive compounds targeting Leishmania NMT, identifying potent inhibitors that could serve as new drug candidates.MethodThe extract of A. absinthium was analyzed using High-Performance Liquid Chromatography (HPLC), identifying nine phenolic compounds, with kaempferol (10.72%) and chlorogenic acid (4.43%) being the most abundant. …”
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1936
The differences in microbial communities and Tick-Borne pathogens between Dermacentor marginatus and Hyalomma asiaticum collected from the Northwestern Xinjiang Uygur Autonomous Re...
Published 2025-08-01“…Abstract Background Ticks are important vectors for the transmission of pathogens, including viruses, bacteria, and protozoa. …”
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1937
Magnetic Nanoparticles with On-Site Azide and Alkyne Functionalized Polymer Coating in a Single Step through a Solvothermal Process
Published 2024-09-01“…<b>Methods</b>: The composition, morphology, and magnetic properties of the nanospheres were analyzed using Transmission Electron and Atomic Force Microscopies (TEM, AFM), Nuclear Magnetic Resonance (NMR), X-ray Diffraction Diffractometry (XRD), Fourier-Transform Infrared Spectroscopy (FT-IR), Matrix-Assisted Laser Desorption/Ionization (MALDI) and Vibrating Sample Magnetometry (VSM). …”
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1938
Causal association between gut microbiota and endometrial cancer in European and East Asian populations: a two-sample Mendelian randomization study
Published 2025-06-01“…The inverse variance-weighted(IVW) method was applied to evaluate the association between gut microbiota composition and EC risk. …”
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1939
Three-dimensional fracture migration evolution law of overburden rock in steeply dipping working face
Published 2025-02-01“…Based on the engineering background of steeply dipping longwall and large mining height working face, the research methods of numerical calculation, field measurement and theoretical analysis are combined. …”
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1940
Single-cell RNA sequencing uncovers abnormal Sertoli-cell elevation and testicular niche impairment in the transfemales’s testis
Published 2025-07-01“…However, the testicular impacts of feminising hormones present heterogeneity due to the complexity of testicular regulatory mechanisms. Method In this study, we analyzed approximately 49,385 single-cell transcriptomes from transfemale human testicular tissue, comparing cellular composition with that of cisgender male individuals across a range of ages. …”
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