Atrophy of hypothalamic subregions increases migraine risk: cross-sectional study and mendelian randomization analysis by Zhonghua Xiong, Lei Zhao, Geyu Liu, Dong Qiu, Yanliang Mei, Xiaoshuang Li, Zhi Guo, Peng Zhang, Mantian Zhang, Tianshuang Gao, Jinju Sun, Xin Liu, Yonggang Wang

“…Abstract Background The hypothalamus is a versatile structure comprising several nuclei that play key roles in regulating various biological processes associated with migraine, including hormone secretion, metabolism, circadian rhythm, and autonomic nervous system functions. …”
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Coupling culturomics and metagenomics sequencing to characterize the gut microbiome of patients with cancer treated with immune checkpoint inhibitors by Khoudia Diop, Babacar Mbaye, Somayeh Nili, Alysé Filin, Myriam Benlaifaoui, Julie Malo, Anne Sophie Renaud, Wiam Belkaid, Sebastian Hunter, Meriem Messaoudene, Karla A. Lee, Arielle Elkrief, Bertrand Routy

“…Methods We performed culturomics using fecal samples from 22 patients from two academic centres in Canada and the United Kingdom with NSCLC and cutaneous melanoma treated with ICI (cancer group), comparing their microbiome composition to that of 7 healthy volunteers (HV), along with matching shotgun metagenomics sequencing. …”
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The impact of sports and nutrition interventions on the bodyfat and BMI of primary school children (compared to the effects of a lockdown period while Covid19-pandemic) by Paula Moliterno, Magdalena Heindl, Hanna Rosenauer, Emma Malina-Altzinger, Tamara Konrad, Kurt Widhalm

“…S U M M A R Y: Background & Aims: The increasing rates of overweight and obesity highlight the need for prevention. …”
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Exploring the antibacterial potential of Clidemia hirta leaf extract against the pathogenicity of Pseudomonas aeruginosa: in vitro and in silico approaches by Vignesh Murugesan, Pargovan Palanivel, Gokul Ramesh, Dwarakesh Ganesh, Helan Soundra Rani Michael, Shivakumar Bandhumy Lingam, Rathish Kumar Sivaraman

“…In this study, the extract from Clidemia hirta plant extract was analyzed for antibacterial properties against Pseudomonas aeruginosa and component composition.Material and MethodsThe plant extract was obtained from leaves of C. hirta and its antibacterial activity against P. aeruginosa was determined in Kirby-Bauer disc diffusion assay. …”
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Phytochemicals from <i>Passiflora coriacea</i> Juss. Have Anti-Inflammatory and Neuroprotective Effects in Mouse Models by Samir Castolo-Sanchez, Alejandro Zamilpa, Maribel Herrera-Ruiz, José Luis Trejo-Espino, Blanca Eda Domínguez-Mendoza, Manasés González-Cortazar, Gabriela Trejo-Tapia

“…<b>Background:</b> Neuroinflammatory diseases trigger an inflammatory response and a state of oxidative stress. …”
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IgA Dysfunction Induced by Early-Lifetime Low-Dose Antibiotics Exposure Aggravates Diet–Induced Metabolic Syndrome by Xue Han, Yue Qin, Jielong Guo, Weidong Huang, Yilin You, Jicheng Zhan, Yue Yin

“…<b>Background:</b> Low-dose antibiotic contamination in animal feed is a persistent global food safety challenge. …”
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Virome profiling of Aedes albopictus across urban ecosystems in Guangdong reveals sex-specific diversity by Qianlin Li, Jicheng Huang, Yanrong Zhou, Qin Wu, Jian Zhou, Fengxia He, Lirun He, Yongxia Shi, Cheng Guo, Jun Dai

“…Abstract Background Aedes albopictus mosquitoes are key vectors for arboviruses such as Dengue virus, Zika virus, and Chikungunya virus, posing significant global public health risks. …”
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Rearing system and immune status influence the small intestinal microbiota of IPB-D3 chickens: A full-length 16S rRNA metagenomic approach by Wawan Kuswandi, Cahyo Budiman, Isyana Khaerunnisa, Cece Sumantri

“…Background and Aim: The small intestinal microbiota plays a pivotal role in poultry digestion and immune function. …”
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Dysregulated gastric microbial communities and functional shifts in chronic atrophic versus non-atrophic gastritis: a Helicobacter pylori-Negative observational study by Hong Yao, Tingting Liu, Yiming Chen, Ling She, Tingfeng Wu, Dongsong Liu, Yuhong Deng, Yubin Han, Kai Chen, Jianmin Deng, Jue Zhang, Jinfeng Chen, Fengbin Liu

“…Methods Fourteen CNAG samples and twenty-three CAG samples were collected. …”
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Controlled Coffee Intake Enhances Erythrocyte Deformability, Na,K-ATPase Activity, and GSH/GSSG Ratio in Healthy Young Adults by Dominika Radosinska, Tomas Jasenovec, Alzbeta Golianova, Ivan Szadvari, Rastislav Vazan, Ivona Kovacicova, Denisa Snurikova, Norbert Vrbjar, Jana Radosinska

“…Background: Published studies suggest that regular coffee consumption may reduce the risk of various diseases. …”
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ZeXieYin formula alleviates atherosclerosis by regulating SBAs levels through the FXR/FGF15 pathway and restoring intestinal barrier integrity by Shihan Zhou, Shangbo Hua, Xinyi Chen, Meiling Ni, Jing Liu, Yanqing Wang, Wanning Wu, Anni Ding, Zizhen Qin, Xinyu Yang, Xiaowei Chen, Boran Zhu, Haoxin Wu

“…Abstract Background Atherosclerosis (AS) is the most common cardiovascular disease (CVD), despite an overall declining incidence, AS remains a leading cause of death worldwide. …”
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Radiomics to predict tumor response to combination chemoradiotherapy in squamous cell carcinoma of the anal canal: a preliminary investigation by Andrea Vanzulli, Lucilla Violetta Sciacqua, Filippo Patti, Roza Drebot, Eros Montin, Riccardo Lattanzi, Laura Anna Maria Lozza, Sergio Villa, Davide Scaramuzza

“…Abstract Background Upfront combination chemoradiotherapy (CRT) represents the standard of care for patients affected by stage III squamous cell carcinoma (SCC) of the anal canal, achieving satisfactory results both in terms of overall survival and local disease control. …”
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Microbial Influences on Amyotrophic Lateral Sclerosis: The Gut–Brain Axis and Therapeutic Potential of Microbiota Modulation by Victòria Ayala, Laia Fontdevila, Santiago Rico-Rios, Mònica Povedano, Pol Andrés-Benito, Pascual Torres, José C. E. Serrano, Reinald Pamplona, Manuel Portero-Otin

“…This review explores the potential role of digestive microbiota and its metabolites in ALS progression and investigates therapeutic approaches targeting gut microbiota. Methods: A comprehensive review of the current literature was conducted to assess the relationship between gut microbiota composition, microbial metabolites, and ALS progression in patients. …”
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Influence of light quality on the profiling of metabolites and the status of Lactobacillus community in the phyllosphere of hydroponically grown ginseng by Nooruddin Bin Sadiq, Ji-Eun Lee, Muhammad Hamayun, Seda Nur Kabadayı, Na-Yun Park, Bokyung Lee, Ho-Youn Kim

“…Abstract Background The microbial community within the phyllosphere plays a critical role in plant health and growth by facilitating nutrient uptake, inducing resistance and enhancing tolrance to stress. …”
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Chronodisruption enhances inflammatory cytokine release from visceral adipose tissue in obesity by Lorenza Zinna, Ludovica Verde, Michele Francesco Di Tolla, Luigi Barrea, Alessia Parascandolo, Federica D’Alterio, Annamaria Colao, Pietro Formisano, Vittoria D’Esposito, Giovanna Muscogiuri

“…Abstract Background Chronodisruption, marked by circadian rhythm misalignment, is linked to inflammatory diseases like obesity. …”
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Dynamic relationship between gut microbiota and post-necrotizing pancreatitis: insights from a multi-stage 16S rRNA sequencing study by Jiongdi Lu, Jiongdi Lu, Zhe Wang, Zhe Wang, Feng Cao, Feng Cao, Jia Li, Guofeng Ji, Guofeng Ji, Fei Li, Fei Li

“…Although previous studies have established a connection between gut microbiota dysbiosis and the onset of necrotizing pancreatitis, the composition of GM in patients who have experienced post-NP post-necrotizing pancreatitis remains largely unexamined.MethodsWe conducted a single-center, prospective, long-term follow-up study of 88 participants, including 68 NP patients and 20 healthy controls. …”
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Bioinformatic analysis and experimental verification reveal expansion of monocyte subsets with an interferon signature in systemic lupus erythematosus patients by Jimin Zhang, Wuwei Zhuang, Yan Li, Chaoqiong Deng, Jingxiu Xuan, Yuechi Sun, Yan He

“…Abstract Background Systemic lupus erythematosus (SLE) is a complex autoimmune disorder characterized by chronic inflammation and multi-organ damage. …”
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Sex-dependent modulation of T and NK cells and gut microbiome by low sodium diet in patients with primary aldosteronism by Hanna F. Nowotny, Tingting Zheng, Thomas Marchant Seiter, Jing Ju, Holger Schneider, Matthias Kroiss, Anna-Lina Sarkis, Lisa Sturm, Vera Britz, Andreas Lechner, Andreas Lechner, Anne L. Potzel, Anne L. Potzel, Anne L. Potzel, Sonja Kunz, Martin Bidlingmaier, Klaus Neuhaus, Adrian Gottschlich, Adrian Gottschlich, Adrian Gottschlich, Adrian Gottschlich, Sebastian Kobold, Sebastian Kobold, Sebastian Kobold, Nicole Reisch, Melanie Schirmer, Martin Reincke, Christian Adolf

“…Here, we analyze the impact of a moderate dietary sodium restriction on microbiome composition and immunophenotype in patients with PA.MethodsProspective two-stage clinical trial including two subgroups: 15 treatment-naive PA patients compared to matched normotensive controls; and 31 PA patients on mineralocorticoid receptor antagonist treatment before and three months after sodium restriction. …”
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Glycemic Index Values of Stiff Porridge (Ugali) Prepared from Maize, Millet, and Sorghum Flours: Which One for Diabetes Management? by Lorraine Amwoma, Rebecca Ebere, Joshua Arimi

“…To determine the GI of ugali prepared from maize, millet, and sorghum and establish the impact of fermented milk on the GI. Methods. Proximate composition was determined using the Association of Official Analytical Chemists methods. …”
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Hyperspectral Target Detection Based on Macro&#x2013;Micro Spectrum Contrastive Learning by Jiacheng Tian, Dunbin Shen, Wenfeng Kong, Min Li, Hongyu Wang, Xiaorui Ma

“…Lastly, to signalize the target and suppress the background, a composite loss is designed to maximize the average distance between the target and background in feature space. …”
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