Exploring bladder cancer through urinary microbiota: innovative “urinetypes” classification and establishment of a diagnostic model by Zhaoyang Sheng, Jing Liu, Maoyu Wang, Xiang Chen, Jinshan Xu, Chen Zhang, Yang Xu, Hui Zhang, Jinpeng Zhu, Nan Qin, ShuXiong Zeng, Zhijun Zheng, ZhenSheng Zhang

“…Abstract Background Bladder cancer (BCa) is a prevalent and lethal malignancy of the urinary system. …”
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Establishment of a new approach for quality evaluation of Pseudobulbus Cremastrae seu Pleiones (Shancigu) based on multicomponent analysis and anti-liver cancer pharmacological eff... by Yuxin Cao, Zhuangzhuang Hao, Mengmeng Liu, Jingwen Xue, Yuqing Wang, Tingyue Jiang, Ge Zhang, Wenxin Fan, ChunGuo Wang, Jinli Shi

“…Shancigu is classified into two commercial specifications—“Maocigu” and “Bingqiuzi”—which exhibit significant differences in appearance, chemical composition, and price, posing challenges for the quality control of medicinal materials.PurposeThe aim of this study was to clarify the quality evaluation indicators based on the anti-liver cancer active components in Shancigu and to establish a reliable quality evaluation method to preliminarily assess the quality of Shancigu from different commercial specifications and production areas.MethodsTwenty-six batches of Shancigu samples were collected. …”
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Effect of fiber-modified kombucha tea on gut microbiota in healthy population: A randomized controlled trial (RCT) by Beatriz Arce-López, Guadalupe X. Bazan, Susana Molina, Maria Carmen Crespo, María García-Beccaria, Silvia Cruz-Gil, Cristina M. Fernández-Díaz, Ana Ramírez de Molina, Ricardo Ramos-Ruiz, Maria Isabel Espinosa-Salinas

“…Objective: This study aimed to evaluate the effects of fiber-enriched kombucha tea on biochemical parameters and gut microbiota composition in a healthy population. Methods: A randomized, double-blind, parallel nutritional intervention trial was conducted with 60 participants (58 completed: 42 women and 16 men; mean ± SD age: 39.79 ± 14.58 years). …”
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Muscular strength and endurance adaptations to functional resistance training in young elite field hockey players by Alper Cenk Gürkan, Meriç Eraslan, Serhat Aydın, Tolga Altuğ, Mustafa Türkmen, Mehmet Söyler, Mustafa Alper Mülhim, Musa Şahin, Baykal Karataş, İbrahim Orkun Akcan, Hamza Küçük

“…BackgroundFunctional strength training (FST) has gained considerable attention due to its potential in enhancing muscle strength, endurance, and body composition, especially among athletes. …”
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Characteristics of upper and lower respiratory tract microbiota after lung transplantation by Yuhang Cai, Yuchen Fan, Ao Chen, Xiaohua Wang, Lulin Wang, Jiaqi Chen, Zhang Wang, Jia Li, Xinzhu Yi, Chunrong Ju

“…Abstract Background The composition and characteristics of airway microbiota offer critical insights for clinical decision-making. …”
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Impact of metabolic and nutritional disorders on the synergy between radiotherapy and immunotherapy in non-small-cell lung cancer by Haiyan Chen, Yaner Yu, Shuangqiu Zhu, Jian Zhao, Yan Ma, Zhifei Huang, Hao Jiang, Qichun Wei

“…Methods Metastatic non-small-cell lung cancer (mNSCLC) patients who received concurrent RT and ICIs between 2018 and 2023 were included in this study. …”
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Rationale and design of Healthy Kids Beyond the Bell: a 2x2 full factorial study evaluating the impact of summer and after-school programming on children’s body mass index and heal... by R. Glenn Weaver, Michael W. Beets, Elizabeth L. Adams, Andrew T. Kaczynski, Brian Chen, Bridget Armstrong, Sarah Burkart, Keagan Kiely, Aliye B. Cepni, James W. White, Olivia Finnegan, Meghan Savidge, Hannah Parker, Griffin A. T. Randolph

“…Methods The study will employ a 2x2 factorial design. …”
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Induction of phospholipase A2 group 4C by HCV infection regulates lipid droplet formation by Masahiko Ito, Jie Liu, Masayoshi Fukasawa, Koji Tsutsumi, Yumi Kanegae, Mitsutoshi Setou, Michinori Kohara, Tetsuro Suzuki

“…Background & Aims: Hepatic steatosis, characterized by lipid accumulation in hepatocytes, is a key diagnostic feature in patients with chronic hepatitis C virus (HCV) infection. …”
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Single-cell analysis reveals tumour size as a key driver of immune cell profile alterations in primary breast tumours and corresponding lymph nodes by Marit Otterlei Fjørtoft, Øystein Garred, Ole Christian Lingjærde, Karin Teien Lande, Lars Ottestad, Inger Riise Bergheim, OSBREAC, Jon Lømo, Colin LaMont, June Helen Myklebust, Hege Russnes, Kanutte Huse, Inga Hansine Rye

“…Abstract Background At diagnosis, 30–40% of women with breast cancer have metastases in sentinel (SN) or axillary lymph nodes (ALN). …”
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Dietary n-3 PUFA May Attenuate Experimental Colitis by Cloé Charpentier, Ronald Chan, Emmeline Salameh, Khaly Mbodji, Aito Ueno, Moïse Coëffier, Charlène Guérin, Subrata Ghosh, Guillaume Savoye, Rachel Marion-Letellier

“…The aim of this study was to evaluate the dietary effect of PUFA composition on intestinal inflammation. Methods. Animals received diet varying in their PUFA composition for four weeks before TNBS-induced colitis. …”
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Association between oral microbial nitrate metabolism and poor prognosis in acute ischemic stroke patients with a history of hypertension by Yueran Ren, Jingru Liang, Weike Hu, Jiahui Xie, Yifeng Zheng, Wei Song, Jiajia Zhu, Hongwei Zhou, Qiheng Wu, Yan He, Jia Yin

“…Background Oral microbes mediate the production of nitric oxide (NO) through the denitrification pathway. …”
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The use of a trench candle as an alternative heating and light source in wartime and possible negative consequences by O. O. Kovalyov, Yu. M. Kolesnyk, V. O. Zub, A. I. Sevalniev, L. P. Sharavara, I. M. Andrusyshyna, O. V. Hancheva, K. O. Kovalov

“…Materials and methods. The content of ultrafine aerosol emitted from trench candle burning was studied using a NanoScan 3910 portable scanning spectrometer. …”
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Single-Cell Landscape and a Macrophage Subset Enhancing Brown Adipocyte Function in Diabetes by Junfei Gu, Jiajia Jin, Xiaoyu Ren, Xinjie Zhang, Jiaxuan Li, Xiaowei Wang, Shucui Zhang, Xianlun Yin, Qunye Zhang, Zhe Wang

“…Background Metabolic dysregulation is a hallmark of type 2 diabetes mellitus (T2DM), in which the abnormalities in brown adipose tissue (BAT) play important roles. …”
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Gut microbiome alterations in immune thrombocytopenia: a systematic review of current evidence by Alireza Khiabani, Roohollah Mirzaee Khalilabadi, Hajar Mardani Valandani, Zahra Khoshnegah, Alireza Khanahmad, Hojat Shahraki, Najmeh Nezamabadipour, Alireza Farsinejad, Alireza Farsinejad, Mehran Rahimlou

“…BackgroundImmune thrombocytopenia (ITP) is an autoimmune disorder characterized by immune-mediated platelet destruction and impaired platelet production. …”
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The Effect of Fitness on Performance, Exertion, and Cognition During Simulated Firefighter Occupational Tasks by Philip J. Agostinelli, Nicholas C. Bordonie, Braxton A. Linder, Ann M. Robbins, Parker L. Jones, Lee F. Reagan, C. Brooks Mobley, Matthew W. Miller, William M. Murrah, JoEllen M. Sefton

“…We aim to determine fitness’s influence on performance, exertion, and cognition during simulated firefighter occupational tasks. <b>Methods:</b> Two baseline fitness assessments occurred to measure aerobic fitness, strength, power, and body composition in 33 non-firefighter participants (females/males: 15/18; 25.18 ± 4.06 years; 174.01 ± 9.77 cm; 75.94 ± 13.18 kg). …”
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Survey on food dyes additives in food products commonly consumed by Algerian children by Djihad Bencherit, Naila Charbi, Asma Saad, Sara Dahia, Bochra Messadi, Mohamed Lounis

“…Background Children are generally attracted to colorful foods. …”
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Astragaloside IV alleviated bone loss in mice with ovariectomy-induced osteoporosis via modulating gut microbiota and fecal metabolism by Huichao Wang, Huichao Wang, Zhongyue Huang, Guangnan Chen, Yang Li, Yang Li, Youwen Liu, Huijie Gu, Yujing Cao, Yujing Cao

“…BackgroundAstragaloside IV (AS-IV) is one of the most potent components of Astragalus. …”
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Protective Effect of Obeticholic Acid on Sepsis-Induced Liver Dysfunction via Regulating Bile Acid Homeostasis by Jiahui Wang, Li Ma, Yuan An, Yan Ge, Dan Xu, Enqiang Mao

“…<b>Background/Objectives:</b> Abnormal bile acid (BA) pool may play an important role in inducing liver damage in sepsis. …”
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Biophysical and biochemical signatures of pancreatic stellate cell activation: insights into mechano-metabolic signalling from atomic force microscopy and Raman spectroscopy by Jacek J. Litewka, Monika A. Jakubowska, Marta Targosz-Korecka, Ewelina Wiercigroch, Jakub Dybas, Natalia Cisak, Zbigniew Madeja, Pawel E. Ferdek

“…As the stromal microenvironment actively communicates with epithelial and vascular compartments, understanding this mechano-metabolic signalling axis is critical for uncovering novel mechanisms of tissue remodelling. Methods To investigate the biomechanical and biochemical alterations during stellate cell activation, we employed atomic force microscopy and Raman spectroscopy to measure changes in cell stiffness, morphology, and molecular composition. …”
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Associations of Social Vulnerability and Race‐Ethnicity With Gastrointestinal Cancers in the United States by David J. Fei‐Zhang, David J. Bentrem, Jeffrey D. Wayne, Lifang Hou, Peiwen Fei, Timothy M. Pawlik

“…The Social Vulnerability Index (SVI), a validated large‐data SDoH‐tool, quantifiably characterizes the interrelatedness of SDoH‐impact through dynamic, region‐contextualized measures. Methods This retrospective cohort study assessed GIC patients (20+ years) between 2013 and 2017 from the Surveillance, Epidemiology, and End Results (SEER) database for total and subcomponent social vulnerability associations across 15 SDoH‐variables encompassing themes of socioeconomic status, minority‐language status, household composition, and housing‐transportation measured by the Social Vulnerability Index (SVI). …”
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