Integrative Analysis of Arachidonic Acid Metabolism in the Pathogenesis and Immune Dysregulation of Psoriasis by Hou M, Sun Y

“…Single-sample gene set enrichment analysis (ssGSEA) and immune cell composition analysis were conducted to explore functional implications. …”
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Comparative analysis of actinorhizal nodule and associated soil microorganism diversity and structure in three Alnus species by Aizi Tong, Wei Liu, Xiaoliang Liu, Junyi Zhu, You Zhou, Jianhua Li

“…In addition, it remains unclear about the influence of the host species and habitats on the microbial community of alder root nodules and rhizospheric soils.MethodsIn this study we sequenced the hyper-variable regions of the 16S rRNA from the root nodules and their rhizosphere soils of three alder species (Alnus mandshurica, A. sibirica, A. japonica) in northeastern China to explore the diversity, composition, network association, and nitrogen cycling pathway of the microbial communities in the actinorhizal nodules and associated soils.ResultsThe results showed that the microbial community α-diversity decreased significantly from the associated soil to the root nodule, and the microbial diversity in the root nodule of A. sibirica was not affected by the habitats. …”
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LSD1 inhibition attenuates targeted therapy-induced lineage plasticity in BRAF mutant colorectal cancer by Christopher A. Ladaika, Averi Chakraborty, Ashiq Masood, Galen Hostetter, Joo Mi Yi, Heather M. O’Hagan

“…Enteroendocrine cells (EECs), the neuroendocrine cell of the intestine, are uniquely present in BRAF mutant CRC as compared to BRAF wildtype CRC. Methods BRAF plus EGFR inhibitor treatment induced changes in cell composition were determined by gene expression, imaging and single cell approaches in multiple models of BRAF mutant CRC. …”
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Contamination of Norway Spruce (Picea abies (L.) H. Karst.) Needles with Heavy Metals under Conditions of Technogenic Emissions by Galina V. Kalko, Alexander E. Andreev

“…Low levels of pollution have been noted near highways in the Luybansky Forestry of the Leningrad Region, 5 and 12 km from the Cherepovets State District Electric Power Station. The elemental composition of the needles at all sites has been characterized by a slightly lower content of Cu, Ni, Mn, and Zn and a significantly higher amount of Pb, Cd, and Cr than in the background stands of Northern Europe. …”
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A maternal sweet diet is associated with the gut dysbiosis in the first trimester of pregnancy by Navid Momeni, Seyedeh Neda Mousavi, Hossein Chiti, Siamak Heidarzadeh

“…Abstract Background The composition of maternal gut phylum in each trimester of pregnancy has been associated with fetal development, separately. …”
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Metabolic Alterations in Women with Lipedema Compared to Women with Lifestyle-Induced Overweight/Obesity by Małgorzata Jeziorek, Maciej Wuczyński, Monika Sowicz, Agnieszka Adaszyńska, Andrzej Szuba, Angelika Chachaj

“…Background: Lipedema is a chronic disorder characterized by disproportionate fat accumulation in the extremities, predominantly affecting women. …”
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Safety of maternal creatine supplementation: evidence from a guinea pig model of full-term pregnancy by Alice K. Freeman, Rebecca M. Dyson, Mary J. Berry, Stacey J. Ellery

“…Background Maternal creatine supplementation, whereby a mother consumes creatine throughout pregnancy to increase fetal creatine levels, has been proposed as a prophylactic therapy for improving developmental outcomes in cases of fetal growth restriction, preterm birth, or perinatal hypoxia. …”
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Attitudes toward child well-being in diverse families across Europe by Anne Solaz, Anne-Rigt Poortman, Dimitri Mortelmans, Laura Bernardi, Anja Steinbach

“…BACKGROUND: European families have diversified, with more children raised in single-parent, step-parent, and same-sex parent families. …”
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Characterization of the hepatic flora and metabolome in nonalcoholic fatty liver disease by Hua Jiang, Hui Wang, Yangfan Guo, Yankun Zhu, Hui Dai, Chenchen Liang, Jianpeng Gao, Jianpeng Gao

“…Background/aimThe purpose of this study was to examine the hepatic bacterial composition and metabolome characteristics of patients with NAFLD using 16S rDNA sequencing and metabolomics. …”
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Arecoline Triggers Psychostimulant Responses by Modulating the Intestinal Microbiota to Influence Neurotransmitter Levels and Digestive Enzyme Activity by Jiaxin Di, Shiqin Xie, Junxi Shen, Leyao Fang, Zhoujin Tan, Xuejuan Liang

“…Arecoline is the main active component responsible for its medicinal effects and plays a key role in its central nervous system (CNS) stimulant properties. <b>Methods:</b> This study investigated the excitatory effects of arecoline by analyzing behavioral changes in mice, neurotransmitter levels, the intestinal microbiota composition, and enzymatic activities. …”
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Comparison of gastric microbiota in patients with different gastric lesions in high and low risk areas of gastric cancer by Liying Lin, Wanxin Li, Lingjun Yan, Xiaoxiong Guo, Mingkai Zhuang, Fenglin Chen, Weimin Ye

“…Abstract Background Variation in gastric cancer (GC) incidence across different geographic areas persists, even when there are similar prevalence rates of Helicobacter pylori (H. pylori) infection. …”
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The Effect of Nutritional Mobile Apps on Populations With Cancer: Systematic Review by Krystal Lu Shin Ng, Murallitharan Munisamy, Joanne Bee Yin Lim, Mustafa Alshagga

“… BackgroundLimited access to nutrition support among populations with cancer is a major barrier to sustainable and quality cancer care. …”
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Mapping the complexity and diversity of tertiary lymphoid structures in primary and peritoneal metastatic gastric cancer by Carolina Martinez-Ciarpaglini, Tanja D de Gruijl, Daniela S Thommen, Nicole C T van Grieken, Joep Grootjans, Sarah Derks, Tessa S Groen-van Schooten, Rosalia Franco Fernandez, Emma N Bos, Jens Seidel, Job Saris, Tania C Fleitas

“…We, therefore, hypothesize that immune cell composition and function of TLS depends on tumor location and the tumor immune environment.Methods Spatial transcriptomics and immunohistochemistry were used to characterize the phenotype of CD45+ immune cells inside and outside of TLS using archival resection specimens from GC primary tumors and peritoneal metastases.Results We identified significant intrapatient and interpatient diversity of the cellular composition and maturation status of TLS in GC. …”
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Assessing the impact of paternal emigration on children ‘left-behind’—A cohort analysis by Natalia Norori, Lucy Barrass, Maria Theresa Redaniel, Nanette R. Lee, Laura D. Howe, Duleeka Knipe

“…Background: Previous work has shown that children ‘left-behind’ as a consequence of parental migration experience worse outcomes, although the majority of this evidence focuses on short- rather than long-term effects. …”
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The Vaginal Microbiota, Human Papillomavirus, and Cervical Dysplasia—A Review by Justė Kazlauskaitė, Guoda Žukienė, Vilius Rudaitis, Daiva Bartkevičienė

“…<i>Background and Objectives:</i> The relationship between the vaginal microbiota, human papillomavirus infection (HPV), and cervical precancerous lesions is a critical area of research, as it influences both the progression of HPV-related diseases and potential treatment strategies. …”
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Low-methoxy pectin-containing enteral nutrition in critical care for intestinal tolerance (LOME-PECT): Study protocol for a randomized controlled trial. by Shizuka Kashiwagi, Shunsuke Takaki, Yasufumi Oi, Hiroshi Honzawa, Ryo Yamamoto, Ikutaro Yamashita, Izumi Ohki, Shigeki Fujitani, Akiyoshi Nagatomi, Yuki Ohshima, Minoru Yoshida, Hideki Yoshida, Miyuki Kurisu, Yuji Takahashi, Hideki Hashimoto, Yasuaki Koyama, Junji Hatakeyama, Satoru Shinoda, Nobuyuki Yokoyama, Kensuke Nakamura

“…We herein conducted a randomized controlled trial (RCT) to test the hypothesis that the administration of an enteral formula containing low-methoxy pectin, a type of dietary fiber, more effectively ameliorates diarrhea in critically ill adult patients than a similar composition without pectin.<h4>Methods</h4>A protocol for planning a multicenter, parallel-group, open-label RCT is described herein. …”
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The Intake of Sucrose but Not of the Intense Sweetener Sucralose Is Associated with Postprandial Endotoxemia in Healthy Young Adults by Raphaela Staltner, Anja Baumann, Ina Bergheim

“…Background and objectives: Similar to saturated fat, a diet rich in sugar may contribute to the development of overweight and obesity and associated metabolic diseases, like type 2 diabetes and metabolic dysfunction associated steatotic liver disease (MASLD). …”
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Gut microbiota changes in patients with hypertensive disorders and gestational diabetes in early pregnancy: a prospective cohort study by Zhihua Zuo, Shanshui Zeng, Xinyi Ou, Lijun Du, Yongcan Guo

“…Abstract Background The potential impact of metabolic diseases during pregnancy is of increasing interest. …”
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Age- and Sex-Specific Gut Microbiota Signatures Associated with Dementia-Related Brain Pathologies: An LEfSe-Based Metagenomic Study by Sun Hwa Hong, Hyun Woong Roh, You Jin Nam, Tae Wi Kim, Yong Hyuk Cho, Sang Joon Son, Chang Hyung Hong

“…Background/Objectives: Emerging evidence suggests that gut microbiota composition is influenced by both age and sex and may contribute to dementia-related brain pathologies. …”
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Biodegradable mulch as microclimate modification effort for improving the growth of horenso; Spinacia oleracea L. by A. Iriany, F. Hasanah, D. Roeswitawati, M.F. Bela

“…METHODS: This study was carried out using a simple randomized complete block design with one control (without mulch) and five treatments (biodegradable mulch compositions), namely the percentage of water hyacinth (40-80%) and coconut coir (20-60%).  …”
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