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1301
Hydrophobic Ion Pairing of Polymyxin B with Oleic Acid: A Dissipative Particle Dynamics Simulation Study
Published 2025-04-01“…<b>Background:</b> Hydrophobic ion pairing is a technique for reducing the hydrophilicity of charged molecules (drugs) by pairing them with oppositely charged hydrophobic counterions. …”
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1302
Phytochemical profiling and antioxidant assessment of Cassia auriculata leaves via GC-MS
Published 2025-06-01“…Background: This research aimed to investigate the phytochemical composition, quantify key bioactive compounds such as phenolics and flavonoids, analyze the secondary metabolite profile using GC-MS on methanolic leaf extracts, and evaluate the antioxidant capacity via the DPPH assay. …”
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1303
Effect of drought disturbance in a sclerophyll forest on the micromammal community in the Río Clarillo National Park, Metropolitan Region, Chile
Published 2025-01-01“…Abstract Background Micromammals play an important role in mediterranean ecosystems. …”
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1304
Anterior intra-pelvic approach and corona mortis vascular anastomoses: A clinical anatomical study shows high frequency
Published 2020-01-01“…Background/Aim. Corona mortis vascular anastomoses (CMVA) must be located during surgical gold standard treatment method for displaced acetabular fractures. …”
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1305
SCITUNA: single-cell data integration tool using network alignment
Published 2025-03-01“…Despite numerous proposed batch correction methods, many still have limitations, such as outputting only dimension-reduced data, relying on computationally intensive models, or resulting in overcorrection for batches with diverse cell type composition. …”
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1306
Philotypes of intestinal microbiotes in patients with arterial hypertension and abdominal obesity
Published 2020-12-01“…The survey included standard clinical, laboratory and instrumental methods. The content of the main GM phylotypes was determined by identifying the total bacterial DNA and DNA of Firmicutes, Bacteroidetes and Actinobacteria using the method of quantitative real-time polymerase chain reaction. …”
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1307
Potential Effect of Defatted Mealworm Hydrolysate on Muscle Protein Synthesis in C2C12 Cells and Rats
Published 2024-12-01“…(1) Background: the objective of this study was to examine the impact of defatted mealworm hydrolysate (DMH), formulated through protein hydrolysis, on muscle protein synthesis in C2C12 cells and rats; (2) Methods: C2C12 cells were treated with dexamethasone and DMH, and cell viability was quantified using the MTT assay. …”
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1308
Spirulina as functional food: insights into cultivation, production, and health benefits
Published 2024-10-01“…Background: Spirulina (Arthrospira platensis), a filamentous cyanobacterium, is renowned as a superfood due to its rich nutritional composition, including proteins, carbohydrates, essential fatty acids, vitamins, minerals, and phytochemicals. …”
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1309
Antihyperglicemic effect of Musa paradisiaca extract in vivo
Published 2025-04-01“…Background: Musa paradisiaca has been widely studied for its antihyperglycemic effects, showing potential as an alternative natural remedy for diabetes. …”
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1310
Antidiarrheal potential of Nigella sativa L. infusion in mice: a phytochemical and efficacy evaluation
Published 2025-01-01“… Background Nigella sativa L., commonly known as black cumin, is a medicinal plant widely recognized for its therapeutic properties. …”
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1311
Nephroprotective peptides of Laennec® in the context of pharmacotherapy for nephro-hepato-metabolic disorders
Published 2024-02-01“…Background. Renal-hepatic dysfunction, which often occurs in liver dysfunction, requires the use of effective and safe nephroprotective agents. …”
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1312
Modulatory effects of Kratom extract on the gut microbiota of rats: implications for health
Published 2025-02-01“…Abstract Background Kratom (Mitragyna speciosa), a plant native to Southeast Asia, is commonly used as a supplement for fatigue, pain relief, mood enhancement, and euphoria. …”
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1313
Differential Lipid Signatures of Lumbar and Cisternal Cerebrospinal Fluid
Published 2024-11-01“…Background: The molecular composition of cerebrospinal fluid (CSF) is often used as a key indicator of biochemical alterations within distinct brain and spinal cord fluid compartments. …”
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1314
Circadian rhythm perturbation causes IBS-like characteristics and altered fecal metabolome in mice
Published 2025-05-01“…This study aimed to explore the effects of dysregulated circadian rhythm on visceral sensitivity, colonic permeability, gut microbial composition, and metabolism in mice. Methods A murine model of circadian rhythm disturbance was built by performing a 6-hour phase delay. …”
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1315
In Vitro Ruminal Metagenomic Profiles and Ruminal Fermentation Variables of Aromatic Plant Pulps
Published 2025-07-01“…ABSTRACT Background Aromatic plant residues remaining after aromatic oil extraction represent a promising alternative feed source due to their rich bioactive compound content and fibrous structure. …”
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1316
In vitro fermentation characteristics of polysaccharide from Scrophularia ningpoensis and its effects on type 2 diabetes mellitus gut microbiota
Published 2025-05-01“…Methods During in-vitro fermentation of Scrophularia ningpoensis (known as Xuanshen) polysaccharide (SNP) by T2DM gut microbiota, effects of SNP on the gas content, production of short-chain fatty acids (SCFAs), metabolite profile and microbiota composition were studied. …”
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1317
Unravelling the microbiome of wild flowering plants: a comparative study of leaves and flowers in alpine ecosystems
Published 2024-10-01“…Abstract Background While substantial research has explored rhizosphere and phyllosphere microbiomes, knowledge on flower microbiome, particularly in wild plants remains limited. …”
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1318
Diagnostic potential of gut microbiota in Parkinson’s disease
Published 2020-01-01“…The gut microbiota is one of the potential sources of biomarkers, changes in the composition of which in PD are actively studied.The aim of this study is to identify microbiota biomarkers in the Parkinson’s disease with an estimated accuracy of the diagnostics, including differential diagnostics, relative to other neurological diseases for patients of the Russian population.Material and methods. …”
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1319
Qualitative analysis and exploration of anti-inflammatory and antibacterial effects of a Thai traditional medicine formula from Wat Pho beyond its use for COVID-19 treatment
Published 2025-04-01“…Abstract Background Ya-Kao (YK) is a traditional Thai medicine used to relieve fever and consists of 14 crude drugs. …”
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1320
Effect of Tapuy (Philippine Rice Wine) Lees on the Gut Microbiota Profile and Lifespan under Normal and Stress Conditions in Drosophila melanogaster
Published 2024-12-01“…To address this, the current study investigated the potential health effects of Tapuy lees consumption using Drosophila melanogaster as model. Methods: The effects of four Tapuy lees variants on the gut microbiome composition and lifespan under normal, heat stress, and starvation stress conditions were tested in D. melanogaster compared to a media-only negative control and the prebiotic inulin as positive control. …”
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