Regularized win ratio regression for variable selection and risk prediction, with an application to a cardiovascular trial by Lu Mao

“…Abstract Background The win ratio has been widely used in the analysis of hierarchical composite endpoints, which prioritize critical outcomes such as mortality over nonfatal, secondary events. …”
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Better Assessment of Progress of SDG 8 by Satyendra Chakrabartty

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Are ethnic and gender specific equations needed to derive fat free mass from bioelectrical impedance in children of South asian, black african-Caribbean and white European origin?... by Claire M Nightingale, Claire M Nightingale, Alicja R Rudnicka, Christopher G Owen, Angela S Donin, Sian L Newton, Cheryl A Furness, Emma L Howard, Rachel D Gillings, Jonathan C K Wells, Derek G Cook, Peter H Whincup

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Management of large tympanic membrane perforations – A comparative study by Saaketh Boddupalli, Sreenivas Gouripeddi

“…Background: This study aimed to compare the results of tympanoplasty with temporalis fascia graft alone and with composite graft in cases of inactive mucosal-type chronic suppurative otitis media with subtotal and total perforations in graft uptake and hearing improvement. …”
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Effect of thermomechanical aging on marginal fit of three CAD-CAM restorative materials: An in vitro study by Reda Eid Attia, Hussein Ramadan Mohammed, Khaled Mohamed Haggag

“…Background. The present study assessed the impact of thermomechanical aging on the marginal fit of hybrid ceramic, reinforced composite resin, and lithium disilicate ceramic. …”
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Characteristics and Pattern of Calcified Nodule and/or Nodular Calcification Detected by Intravascular Ultrasound on the Device-Oriented Composite Endpoint (DoCE) in Patients with... by Ploy Pengchata, Rungtiwa Pongakasira, Namthip Wongsawangkit, Asa Phichaphop, Nattawut Wongpraparut

“…Background. The characteristics and pattern of a CN and/or NC on clinical outcome remain unknown. …”
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New Composite Indexes through Factor Analysis Simplifying the Interpretation of Health-Related Quality of Life Outcomes of Surgical Adolescent Idiopathic Scoliosis Patients Complet... by Wai-Wang Chau, Bobby Kin-Wah Ng

“…In view of a total of 14 (9 + 5) major domain scores from both questionnaires, this study attempted to develop new composite indexes using factor analysis. Materials and Methods: All operated AIS patients within the years 2014 and 2016 were recruited. …”
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mPEG-PCL Nanoparticles to Improve Oral Bioavailability of Acalabrutinib: Effect of Polymer Lipophilicity and Hydrophilicity on Physicochemical Properties and In Vivo Performance in... by Swagata Sinha, Punna Rao Ravi, Sahadevan Rajesh Rashmi, Łukasz Szeleszczuk

“…<b>Methods</b>: Variations in the mPEG-to-ε-caprolactone ratio influenced both the molecular weight (Mw) of the synthesized co-polymers and their aqueous phase affinity. …”
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Clinical evaluation of SonicFill bulk resin technique in the restoration of proximal deep caries of primary molars: a two-year randomized controlled trial by Yingting Yang, Haihua Lei, Yang Liu, Bin Xia

“…Abstract Background/purpose Traditional restorative composites require time-consuming incremental layering techniques which poses challenges in pediatric dentistry. …”
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Chronic non-bacterial osteomyelitis in children- five-year standardized follow-up of a prospective observational cohort in the pre-biological era by Christine Hofmann, Annette Holl-Wieden, Christiane Reiser, Meinrad Beer, Peter Raab, Henner Morbach, Hermann J. Girschick

“…Methods Patients were assessed at baseline and at 1 (without MRI), 3, 6, 12, 18, 24, 36, 48, 60 months. …”
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Correlations between serum BDNF levels and neurodevelopmental outcomes in infants of mothers with gestational diabetes by Chung-Hao Su, Ta-Yu Liu, I.-Ting Chen, Mei-Chen Ou-Yang, Li-Tong Huang, Ching-Chang Tsai, Chih-Cheng Chen

“…Background: Diabetes during pregnancy is associated with an increased risk of foetal and neonatal complications and long-term complications in the offspring. …”
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A protocol for estimating health burden posed by early life exposure to ambient fine particulate matter and its heavy metal composition: a mother–child birth (ELitE) cohort from Ce... by Tanwi Trushna, Vikas Yadav, Vikas Yadav, Uday Kumar Mandal, Vishal Diwan, Vishal Diwan, Rajnarayan R. Tiwari, Rajnarayan R. Tiwari, Rajesh Ahirwar, Rajesh Ahirwar, Dharma Raj, Sindhuprava Rana, Sindhuprava Rana, Suchitra Vishwambhar Surve, Sagnik Dey, Sagnik Dey, Yogesh Damodar Sabde, Yogesh Damodar Sabde

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Physical activity and factors associated with the costs of low back pain among adults after 18 months of follow-up: a cohort study by Everton Alex Carvalho Zanuto, Valter Penna, Cristiano Rocha da Silva, Enio Ricardo Vaz Ronque, Ruben de Faria Negrão Filho, Robson Chacon Castoldi, Jamile Sanches Codogno, Rômulo Araújo Fernandes

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Association between the nutritional inflammation index and mortality among patients with sepsis: insights from traditional methods and machine learning-based mortality prediction by Yuanshuo Ge, Ding Hu, Zhe Wang, Cheng Zhang

“…Abstract Background Sepsis is a life-threatening condition characterized by dysregulated immune responses and metabolic disturbances. …”
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Evaluating and enhancing the service capacity of secondary public hospitals in urban China: a multi-method empirical analysis based on Guangzhou (2019–2023) by Baoling Wu, Baoling Wu, Wenbo Wu, Xi Wang, Weizhang Huang, Zhenni Luo, Jifeng Li

“…This study aims to systematically evaluate the evolution and spatial dynamics of service capacity among secondary general public hospitals in Guangzhou, offering empirical evidence to support capacity improvement and policy optimization.MethodsA composite evaluation framework was constructed across three dimensions: medical quality, operational efficiency, and sustainability. …”
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Assessing healthcare status and challenges in border regions: insights from Tak and Mae Hong Son provinces, Thailand – a mixed-method approach by Seo Ah Hong, Mathuros Tipayamongkholgul, Chit Su Tinn, Bang-on Thepthien

“…Abstract Background Thailand’s Tak and Mae Hong Son (MHS) provinces, bordering Myanmar, are critical entry points for individuals seeking employment or healthcare. …”
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Efficiency evaluation of phospholipid fatty acid method based on lipid standards: methanol failed to recover a majority of phospholipids yet eluted unexpected glycolipid by Shanshan Zhang, Shanshan Zhang, Xinyu Jiao, Hongzhang Kang, Wenjuan Yu, Wenjuan Yu

“…Overall, incomplete separation among lipid types caused loss of phospholipids and introduction of glycolipid interferences in the methanol fraction, leading to biased estimation of soil microbial biomass and composition. Chloroform elution of phospholipids challenges the principle of “like dissolves like” in solid-phase chromatography, although we cannot rule out the uncertainty caused by background PLFAs and future experiments are needed to provide more evidence. …”
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Towards a Customized Oral Drug Therapy for Pediatric Applications: Chewable Propranolol Gel Tablets Printed by an Automated Extrusion-Based Material Deposition Method by Kristiine Roostar, Andres Meos, Ivo Laidmäe, Jaan Aruväli, Heikki Räikkönen, Leena Peltonen, Sari Airaksinen, Niklas Sandler Topelius, Jyrki Heinämäki, Urve Paaver

“…<b>Background:</b> Automated semi-solid extrusion (SSE) material deposition is a promising new technology for preparing personalized medicines for different patient groups and veterinary applications. …”
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Subnational contribution to life expectancy and life span variation changes: Evidence from the United States by Wen Su, Alyson van Raalte, Jose Manuel Aburto, Vladimir Canudas-Romo

“…BACKGROUND: The US life expectancy has been stagnating in recent decades, and along with this, the time trends of life span variation have shown stagnation and even increases with respect to historical levels. …”
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Modified oil extraction of pristine and weathered synthetic polyurea microcapsules and polyethylene microplastics from soil by Eva-Maria Teggers, Svetlana Heck, Boris Meisterjahn, Markus Simon, Dieter Hennecke, Roman Heumann, Holger Egger, Philipp Dalkmann, Annika Jahnke, Andreas Schäffer

“…After MP isolation, precise MP quantification was facilitated by 14C-radiolabelling of the polymers, which enabled accurate mass balancing while eliminating potential interferences from background polymers. The modified oil extraction method, achieved extraction efficiencies of up to 75% of the applied radioactivity (AR), compared to a maximum efficiency of 62%AR using the conventional density extraction method combined with KOH. …”
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