Association Between Mineralocorticoid Receptor Antagonist Use With Worsening Renal Function and Prognosis in Patients With Acute Heart Failure by Yudai Fujimoto, Yasuyuki Shiraishi, Kazutaka Nogi, Shun Kohsaka, Takashi Kohno, Mitsunobu Kitamura, Yuji Nagatomo, Tomoya Ueda, Maki Nogi, Satomi Ishihara, Yasuki Nakada, Rika Kawakami, Takeshi Kitai, Shogo Oishi, Eiichi Akiyama, Satoshi Suzuki, Masayoshi Yamamoto, Keisuke Kida, Takahiro Okumura, Tsutomu Yoshikawa, Yoshihiko Saito, Yuya Matsue

“…Background Prognostic implications of mineralocorticoid receptor antagonist (MRA) initiation in the context of worsening renal function (WRF) in patients with acute heart failure (AHF) remain unknown. …”
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A Rent Subsidy and Identity Capital Intervention for Youth Exiting Homelessness: Protocol for the Transitioning Youth Out of Homelessness 2.0 Pilot Randomized Controlled Trial by Naomi S Thulien, Rowen K Stark, Alexandra Amiri, Alex Abramovich, Alex Akdikmen, Alexandra Carasco, Mardi Daley, Bernice Downey, Oluwapelumi (Pukky) Fambegbe, Tyler Frederick, Stephen W Hwang, Nicole Kozloff, Amanda Noble, Cheryl Pedersen, Marsha Rampersaud, Ruth Rodney, Tadios Tibebu, Rosane Nisenbaum

“… BackgroundFor young people who have experienced homelessness, relative housing stability alone is insufficient to achieve socioeconomic inclusion. …”
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Features of short-term heart rate variability in internally displaced people with type 2 diabetes mellitus by V.A. Serhiyenko, V.B. Sehin, V.I. Pankiv, A.A. Serhiyenko

“…Background. Internally displaced people (IDP) often face many problems, both physical and psychological. …”
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Active left atrial ejection fraction as a non-invasive marker in pulmonary hypertension secondary to heart failure by Di Zhou, Xin Li, Jing Xu, Yining Wang, Weichun Wu, Arlene Sirajuddin, Shihua Zhao, Zhihong Liu, Minjie Lu

“…ABSTRACT: Background: Patients with pulmonary hypertension (PH) secondary to left heart failure (HF) exhibit a complex pathophysiological profile and poor prognosis. …”
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Genetic polymorphisms in SLC5A2 are associated with clinical outcomes and dapagliflozin response in heart failure patients by Ahmed Essam Abou Warda, Rylie M. Flohr, Rania M. Sarhan, Rania M. Sarhan, Mohamed Nabil Salem, Heba F. Salem, Heba F. Salem, Ayman N. Moharram, Abdullah S. Alanazi, Christelle Lteif, Brian E. Gawronski, Leanne Dumeny, Tariq G. Alsahli, Khaled Elenizi, Bassem Zarif, Neven Sarhan, Julio D. Duarte

“…BackgroundSodium-glucose cotransporter-2 inhibitors (SGLT2i) have emerged as promising therapeutics for heart failure (HF). …”
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Impact of diabetes on three-year outcome after coronary stenting in patients with polyvascular atherosclerotic disease – a secondary analysis of the randomized TWENTE trials by Daphne van Vliet, Tineke H. Pinxterhuis, Eline H. Ploumen, Marlies M. Kok, Rosaly A. Buiten, Paolo Zocca, Ariel Roguin, Carl E. Schotborgh, Rutger L. Anthonio, Peter W. Danse, Edouard Benit, Adel Aminian, Carine J.M. Doggen, Clemens von Birgelen

“…Background: The presence of polyvascular atherosclerotic disease is associated with a high-risk of adverse events following percutaneous coronary intervention (PCI). …”
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Diabetic kidney disease phenotypes and the risk of cardiovascular events: The Silesia Diabetes-Heart Project by Oliwia Janota-Sosińska, Marta Mantovani, Krzysztof Irlik, Hanna Kwiendacz, Anna Olejarz, Patrycja Pabis, Aleksandra Włosowicz-Momot, Julia Piaśnik, Wiktoria Wójcik, Paulina Szromek-Białek, Uazman Alam, Janusz Gumprecht, Gregory Y. H. Lip, Katarzyna Nabrdalik

“…Abstract Background The impact of diabetic kidney disease (DKD) phenotype on the cardiovascular (CV) risk remains ambiguous. …”
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Independent Risk Factors of Non-Resolution Mural Thrombus in ST-Segment Elevation Myocardial Infarction Patients with Left Ventricular Aneurysms by Meng Wang, Mengwan Li, Wenheng Liu, Jian Li, Dan Chen, Ziqing Wang, Qilong Guo, Shouling Mi, Junhua Ge

“…Background: The clinical prognosis of ST-elevation myocardial infarction (STEMI) patients with mural thrombus in left ventricular aneurysm (MTLVA) remains poor; moreover, the risk factors associated with the non-resolution (persistent or recurrent) of MTLVA are not well understood. …”
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A co-created self-care and informal support intervention targeting women with gestational diabetes mellitus in northern Vietnam (VALID-II): a protocol for a two-arm non-randomised... by Ditte S. Linde, Hieu M. Le, Dung T. K. Vu, Ngoc-Anh T. Dang, Ai T. Nguyen, Tuc P. Vu, Xuan-Bai Nguyen, Cuong D. Nguyen, Dan W. Meyrowitsch, Jens Søndergaard, Christina A. Vinter, Ib C. Bygbjerg, Vibeke Rasch, Thanh D. Nguyen, Tine M. Gammeltoft, Dang K. Nguyen

“…Abstract Background Gestational diabetes mellitus (GDM) is a transitory form of diabetes that presents during pregnancy with frequent adverse maternal and neonatal health consequences if left untreated. …”
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Sex Differences in the Prognostic Value of Circulating Biomarkers in Patients Presenting With Acute Chest Pain by Gard Mikael Sæle Myrmel, MD, Nasir Saeed, Ole Thomas Steiro, MD, Hilde Lunde Tjora, MD, PhD, Jørund Langørgen, MD, PhD, Rune Oskar Bjørneklett, MD, PhD, Øyvind Skadberg, MD, Vernon Vijay Singha Bonarjee, MD, PhD, Øistein Rønneberg Mjelva, MD, Eva Ringdal Pedersen, MD, PhD, Kjell Vikenes, MD, PhD, Torbjørn Omland, MD, PhD, Kristin Moberg Aakre, MD, PhD

“…Background: Biomarkers are used for long-term risk prediction of cardiovascular (CV) events in patients presenting with suspected acute coronary syndromes. …”
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Characteristics and Outcomes of Older Patients Undergoing Protected Percutaneous Coronary Intervention With Impella by Philipp Jakob, Alexandra J. Lansky, Mir B. Basir, Michael J. Schonning, Batla Falah, Zhipeng Zhou, Wayne B. Batchelor, Arsalan Abu‐Much, Cindy L. Grines, William W. O'Neill, Barbara E. Stähli

“…Background In patients undergoing high‐risk percutaneous coronary intervention, Impella has become an important adjunctive tool to support revascularization. …”
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Salvage therapy containing sorafenib and donor lymphocyte infusion is associated with improved outcomes for FLT3 wild-type acute myeloid leukemia relapsing after allogeneic hematop... by Zhonghui Jiang, Ya Zhou, Yuxin Bai, Fang Dai, Menglin Fan, Tian Zhang, Danian Nie, Yunxin Zeng, Yirong Jiang, Ping Zhu, Zhiping Fan, Na Xu, Fen Huang, Ren Lin, Min Dai, Xiaojun Xu, Zhangkun Li, Hua Jin, Jing Sun, Qifa Liu, Li Xuan

“…Abstract Background There is no established standard treatment for acute myeloid leukemia (AML) patients with FLT3 wild-type relapsing after allogeneic hematopoietic stem cell transplantation (allo-HSCT). …”
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BMI-residualized data uncovers a cluster of people with type 2 diabetes and increased serum ferritin protected from cardiovascular disease by Laura Gallardo-Nuell, Jordi Blanch, Yenny Leal, Daniel E Coral, Talita Duarte-Salles, Giuseppe N. Giordano, Paul W. Franks, Ewan R. Pearson, Geltrude Mingrone, Carel W le Roux, Rafael Ramos, José Manuel Fernández-Real

“…Abstract Background Understanding the relationship between serum ferritin levels and cardiovascular outcomes in type 2 diabetes is crucial for improving risk stratification and guiding therapeutic interventions aimed at preventing major adverse cardiovascular events (MACE). …”
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Delivery of care in high mortality hospital settings: a direct observational study examining 1848 h of neonatal nursing in KenyaResearch in context by Abdulazeez Imam, Michuki Maina, Jalemba Aluvaala, Vincent Kagonya, Onesmus Onyango, Fredrick Were, Sebastian Fuller, Kenneth Karumba, Mike English, David Gathara, Peter Mwangi, Lucy Kinyua, Lydia Thuranira, Virginia Njoroge, Ngina Mwangi, Loise Mwangi, Penina Musyoka, Zainab Kioni

“…Summary: Background: In resource-constrained countries, deploying better technologies is expected to improve neonatal care but little attention has been paid to the critical role of nurse staffing. …”
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Impact of awake prone positioning duration on intubation or mortality in COVID-19 patients with acute respiratory failure: secondary analysis of a randomized clinical trial by Qin Sun, Rui Zhang, Junyi Zhang, Jianfeng Xie, Yingzi Huang, Yi Yang, Haibo Qiu, Ling Liu, Hui Chen, the Chi-ARDS Net (Chinese ARDS Research Network)

“…Abstract Background Compared with shorter awake prone positioning (APP), prolonged APP (≥ 12 h daily) reduces the intubation rate in patients with COVID-19-related acute hypoxemic respiratory failure (AHRF). …”
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Elevated monocyte-to-high-density lipoprotein ratio is associated with increased risk of cognitive impairment and severe cerebral small vessel disease burden by Yueshan Zhao, Yueshan Zhao, Yueshan Zhao, Meixi Li, Meixi Li, Meixi Li, Meixi Li, Juan Zhang, Chao Wang, Mengyao Zhao, Qishuo Yang, Tianjun Wang, Peiyuan Lv, Peiyuan Lv, Peiyuan Lv, Peiyuan Lv, Peiyuan Lv

“…BackgroundMonocyte-to-high-density lipoprotein ratio (MHR), as a novel biomarker, has shown potential in predicting the onset and progression of various diseases. …”
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The role of left atrio-ventricular coupling index and left atrial ejection fraction in predicting onset of atrial fibrillation and adverse cardiac events in hypertrophic cardiomyop... by Parisi Francesca, La Franca Eluisa, Pistelli Lorenzo, Gentile Giovanni, Bellavia Diego, Nuzzi Vincenzo, Manca Paolo, Massimiliano Mulè, Zito Concetta, Di Bella Gianluca, Scipione Carerj, Cipriani Manlio, Francesco F. Faletra

“…Abstract Background Several predictors of atrial fibrillation (AF) onset in patients with hypertrophic cardiomyopathy (HCM) have been proposed, however, all of them showed limited accuracy. …”
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Antiplatelet Use Prior to Anticoagulant Initiation in Patients With Atrial Fibrillation-Related Ischemic Stroke: An ELAN Trial Analysis by Alexandros A. Polymeris, Masatoshi Koga, Daniel Strbian, Adhiyaman Vedamurthy, Manju Krishnan, Mattia Branca, Thomas Horvath, Martina Goeldlin, Gek Shim, Christoph Gumbinger, Liqun Zhang, Espen Saxhaug Kristoffersen, Philippe Desfontaines, Peter Vanacker, Angelika Alonso, Sven Poli, Ana Paiva Nunes, Nicoletta G. Caracciolo, Markus Kneihsl, Timo Kahles, Daria Giudici, Silja Räty, Marjaana Tiainen, Jesse Dawson, Urs Fischer, for the ELAN Investigators

“…Here, we explored the risks and benefits of this approach. Methods A post-hoc analysis of ELAN (Early versus Late Initiation of Direct Oral Anticoagulants in Post-ischemic Stroke Patients with Atrial Fibrillation) trial data (NCT03148457) was conducted to compare the risk of recurrent ischemic stroke, systemic embolism, major bleeding (extracranial or intracranial hemorrhage [ICH]), and vascular death within 30 days (as a composite and as individual outcomes) in participants treated with and without antiplatelets before DOAC initiation after an AF-associated ischemic stroke. …”
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Determining optimal timing of birth for women with chronic or gestational hypertension at term: The WILL (When to Induce Labour to Limit risk in pregnancy hypertension) randomised... by Laura A Magee, Katie Kirkham, Sue Tohill, Eleni Gkini, Catherine A Moakes, Jon Dorling, Marcus Green, Jennifer A Hutcheon, Mishal Javed, Jesse Kigozi, Ben W M Mol, Joel Singer, Pollyanna Hardy, Clive Stubbs, James G Thornton, Peter von Dadelszen, WILL Trial Study Group

“…<h4>Background</h4>Chronic or gestational hypertension complicates approximately 7% of pregnancies, half of which reach 37 weeks' gestation. …”
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Impact of Pan-Immune Inflammation Value on Short-Term Outcomes and Long-Term Prognosis in Patients with Type A Aortic Dissection by Cai H, Shourav, Shao Y, Shuangling S, Duan C, Zhang C, Wu QC

“…The Pan-Immune Inflammation Value (PIV), a composite index derived from peripheral blood cell counts, has demonstrated prognostic relevance in multiple clinical conditions. …”
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