Comparative effectiveness of lactulose and sennosides for the prevention of peritoneal dialysis-related peritonitis: an open-label, randomized, active-controlled trial by Kajohnsak Noppakun, Tichanun Narongchai, Romanee Chaiwarith, Uraiwan Wongsawad, Surachet Vongsanim, Chidchanok Ruengorn, Surapon Nochaiwong

“…Background To the best of our knowledge, the effectiveness and safety of lactulose in comparison to sennosides, for the prevention of peritoneal dialysis (PD)-related peritonitis, has never been tested in a randomized study.Methods We conducted an open-label, randomized, active-controlled trial in a PD-center in Northern Thailand. …”
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Increasing risk of postlung transplant hospitalizations for infection: An analysis of recent trends by Shi Nan Feng, BSPH, Armaan F. Akbar, BS, Alice L. Zhou, MS, Andrew Kalra, BS, Sean Agbor-Enoh, MD, PhD, Christian A. Merlo, MD, MPH, Errol L. Bush, MD

“…Background: Despite advancements in lung transplantation (LT), infection remains a major cause of morbidity and mortality following LT. …”
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Efficacy of tenofovir on clinical outcomes of COVID-19 patients: a systematic review by Thaís Lorenna Souza Sales, Daniella Nunes Pereira, Virginia Mara Reis Gomes, Gabriel Gouveia de Aguiar, Milena Soriano Marcolino

“…Abstract Background Pharmacological treatments for COVID-19 remain limited, particularly for severe outcomes. …”
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Risk factors, management, and outcomes of amniotic fluid embolism: A multicountry, population-based cohort and nested case-control study. by Kathryn E Fitzpatrick, Thomas van den Akker, Kitty W M Bloemenkamp, Catherine Deneux-Tharaux, Alexandra Kristufkova, Zhuoyang Li, Timme P Schaap, Elizabeth A Sullivan, Derek Tuffnell, Marian Knight

“…<h4>Background</h4>Amniotic fluid embolism (AFE) remains one of the principal reported causes of direct maternal mortality in high-income countries. …”
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Thin Strut CoCr Biodegradable Polymer Biolimus A9-Eluting Stents versus Thicker Strut Stainless Steel Biodegradable Polymer Biolimus A9-Eluting Stents: Two-Year Clinical Outcomes by Ian B. A. Menown, Mamas A. Mamas, James M. Cotton, David Hildick-Smith, Franz R. Eberli, Gregor Leibundgut, Damras Tresukosol, Carlos Macaya, Samuel Copt, Sara Sadozai Slama, Keith G. Oldroyd

“…Background. While thinner struts are associated with improved clinical outcomes in bare-metal stents (BMS), reducing strut thickness may affect drug delivery from drug-eluting stents (DES) and there are limited data comparing otherwise similar thin and thick strut DES. …”
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Serum NT-ProBNP/Chloride Ratio Predicts Adverse Cardiovascular Outcomes in Patients with Acute Heart Failure by Victor José Leal-Alcántara, Eder González-Macedo, Ana Cristina Maldonado-May, Alberto Santiago-Hernández, Eder Jonathan Amaro-Palomo, Sarai Hernandez-Pastrana, Anna Elisa Adib-Gracia, Rodrigo Gopar-Nieto, Daniel Sierra-Lara Martínez, José Luis Briseño-De la Cruz, Héctor González-Pacheco, Alexandra Arias-Mendoza, Diego Araiza-Garaygordobil

“…<b>Background:</b> Heart failure (HF) is a public health issue. …”
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Integrated machine learning and population attributable fraction analysis of systemic inflammatory indices for mortality risk prediction in diabetes and prediabetes by Zixi Zhang, Chenyang Li, Yichao Xiao, Chan Liu, Xiaoqin Luo, Cancan Wang, Yongguo Dai, Qiuzhen Lin, Zeying Zhang, Cheng Zheng, Jiafeng Lin, Tao Tu, Qiming Liu

“…Background Chronic systemic inflammation is a key contributor to cardiometabolic complications in diabetes mellitus (DM) and prediabetes (PreDM). …”
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Assessing the Fortification Quality of Refined Vegetable Oil with Vitamin A, Wheat Flour with Iron, and Salt with Iodine: Findings from a Market Assessment in Senegal, West Africa by Mane Hélène Faye, Marie-Madeleine A Diémé, Phillip M Nkhoma, Adama Diouf, Dora Panagides, Abdou Badiane, Becky L Tsang, Olouwafemi Mistourath Mama, Marielle A De Souza, Nicole Idohou Dossou

“…Background: Mandatory fortification (MF) of wheat flour (WF) with iron/folic acid, refined edible oil with vitamin A (VA), and salt with iodine is implemented to address micronutrient deficiencies in Senegal. …”
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Stratifying risk outcomes among adult COVID-19 inpatients with high flow oxygen: The R4 score by G.M. Aguirre-García, D. Ramonfaur, G. Torre-Amione, M.T. Ramírez-Elizondo, R. Lara-Medrano, J.F. Moreno-Hoyos, E.S. Velázquez-Ávila, C.A. Diaz-Garza, V.M. Sanchez-Nava, F. Castilleja-Leal, G.M. Rhoades, M.F. Martínez-Reséndez

“…This study aims to provide a simple risk stratification system to predict invasive mechanical ventilation (IMV) or death among COVID-19 inpatients on HFO.Methods Among 529 adult inpatients with COVID-19 pneumonia, we selected unadjusted clinical risk factors for developing the composite endpoint of IMV or death. …”
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Efficacy and safety of direct oral anticoagulants compared with warfarin in antiphospholipid syndrome. Results of a multicenter retrospective cohort study by Maha A.T. Elsebaie, Zoe Wickham, Stephanie DeBragga, Stacey Fedewa, Mohamed Amgad, Jane Jungyoon Park, Allen Li, Ali Eshaghpour, Juan Li, Mark Crowther, Manila Gaddh

“…Background: Direct oral anticoagulants (DOACs) have become firstline treatment for many thrombotic conditions, but their use in antiphospholipid syndrome (APS) patients remains controversial. …”
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Sodium–glucose cotransporter-2 inhibitors improve cardiovascular outcomes post-acute coronary syndrome complicated by acute heart failure by Alaa Rahhal, Tahseen Hamamyh, Ammar Chapra, Khaled J. Zaza, Mostafa Najim, Mohammad Hemadneh, Hazem Faraj, Wael Kanjo, Ahmed Yasin, Haneen Toba, Wafa Mohammed, Mohammad Khair Hamad, Nawras Al-Tikrety, Mhd Baraa Habib, Ahmed Awaisu, Ahmed Mahfouz, Sumaya Alyafei, Abdul Rahman Arabi, Ashfaq Patel, Mohammed Al-Hijji, Mohammed Al-Hijji

“…BackgroundAcute coronary syndrome (ACS) remains a risk factor for heart failure (HF). …”
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Randomized trial of ultraviolet irradiation units installed in homes of children and adolescents with asthma by Jonathan A. Bernstein, MD, Anand Seth, PhD, Marepalli Rao, PhD, Janyce C. Katz, JD, Umesh Singh, MD, PhD, William Greisner, MD, Michelle Lierl, MD, Benjamin Prince, MD, Kunjana Mavunda, MD, MPH, Cheryl K. Bernstein, RN, BS, CRCC, Tianyuan Guan, PhD, Amy J. Nation, DO, Amanda K. Rudman Spergel, MD, Alkis Togias, MD, Mark Glazman, PhD

“…Background: Asthma management involves medications with environmental control, but patient adherence to the latter is poor. …”
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Walking as a viable alternative to moderate-to-vigorous physical activity for improving cardiovascular outcomes in coronary artery disease patients by Zejun Yang, Yunting Liang, Liu He, Le Zhou, Xiaodong Peng, Yiwei Lai, Cong Yuan, Xiaoxia Liu, Ning Zhou, Weihua Zhang, Caihua Sang, Qian Tong, Xin Du, Jianzeng Dong, Changsheng Ma

“…Background: Home-based cardiac rehabilitation is recommended for coronary artery disease (CAD) patients, while exercise is the most important component. …”
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Full-Blood Inflammatory Ratios Predict Length of Stay but Not Early Death in Romanian Pulmonary Tuberculosis by Ionut-Valentin Stanciu, Ariadna-Petronela Fildan, Barkha Rani Thakur, Adrian Cosmin Ilie, Livia Stanga, Cristian Oancea, Emanuela Tudorache, Felix Bratosin, Ovidiu Rosca, Iulia Bogdan, Anca Chisoi, Ionela Preotesoiu, Viorica Zamfir, Elena Dantes

“…<i>Background and Objectives</i>: Blood-borne inflammatory ratios have been proposed as inexpensive prognostic tools across a range of diseases, but their role in pulmonary tuberculosis (TB) remains uncertain. …”
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mHealth intervention "ImTeCHO" to improve delivery of maternal, neonatal, and child care services-A cluster-randomized trial in tribal areas of Gujarat, India. by Dhiren Modi, Nishith Dholakia, Ravi Gopalan, Sethuraman Venkatraman, Kapilkumar Dave, Shobha Shah, Gayatri Desai, Shamim A Qazi, Anju Sinha, Ravindra Mohan Pandey, Ankit Anand, Shrey Desai, Pankaj Shah

“…<h4>Background</h4>The coverage of community-based maternal, neonatal, and child health (MNCH) services remains low, especially in hard-to-reach areas. …”
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Plasma microRNA signatures of aging and their links to health outcomes and mortality: findings from a population-based cohort study by Lieke M. Kuiper, Michelle M. J. Mens, Julia W. Wu, Jaap Goudsmit, Yuan Ma, Liming Liang, Albert Hofman, Trudy Voortman, M. Arfan Ikram, Jeroen G. J. van Rooij, Joyce B. J. van Meurs, Mohsen Ghanbari

“…Abstract Background MicroRNAs are small non-coding RNAs that regulate gene expression post-transcriptionally and show differential expression in various tissues with aging phenotypes. …”
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Passive immunotherapy for adults hospitalized with COVID-19: An individual participant data meta-analysis of six randomized controlled trials. by Kirk U Knowlton, Lianne K Siegel, Christina E Barkauskas, Sanjay Bhagani, Nila J Dharan, Edward M Gardner, Robert L Gottlieb, Marie Helleberg, Helene C Highbarger, Thomas L Holland, Christian Kjer Heerfordt, Susana Lazarte, Lindsey M Leither, Joseph Lutaakome, Magdalena Ardelt, Eleftherios Mylonakis, Sean W X Ong, Jeffrey Scott Overcash, Hassan Taha, Phyllis C Tien, Barbara W Trautner, David Vallee, Amy C Weintrob, Giota Touloumi, Abdel G Babiker, STRIVE ACTIV-3/TICO Study Group

“…<h4>Background</h4>Anti-SARS-CoV-2 monoclonal antibodies (mAb) reduce the risk of hospitalization in outpatients with mild-to-moderate COVID-19. …”
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Suicide and suicide attempt in users of GLP-1 receptor agonists: a nationwide case-time-control studyResearch in context by Julien Bezin, Anne Bénard-Laribière, Emilie Hucteau, Marie Tournier, François Montastruc, Antoine Pariente, Jean-Luc Faillie

“…Summary: Background: Glucagon-like peptide-1 receptor agonists (GLP-1 RA) are extensively evaluated for the risk of suicidal behaviors or ideation; the influence of psychiatric history or obesity on this potential effect remains to be investigated. …”
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Hyssopus cuspidatus volatile oil: a potential treatment for steroid-resistant asthma via inhibition of neutrophil extracellular traps by Xu Wang, Hui-Ming Peng, Meng-Ru Zhang, Jing-Jing Li, Chuan-Peng Zhao, Ya-Li Zhang, Si-Yu Wang, Si-Ying Zhu, Jian-Kang Lu, Hai-Long Yin, Qiang Yin, Jin-Bo Fang

“…Abstract Background Steroid-resistant asthma (SRA) is a form of asthma resistant to corticosteroid therapy, which is characterized by the presence of neutrophil-predominant inflammatory response and neutrophil extracellular traps (NETs) formation. …”
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Association Between Size of Left Ventricle and Long‐Term Cardiovascular Events by Yun‐Jiu Cheng, Zi‐Li Liao, Li‐Juan Liu, Yue‐Dong Ma, Xu‐Miao Chen, Ze‐Xuan Wu, Hui‐Qiang Wei, Wei‐Dong Lin, Yi‐Jian Liao, Su‐Hua Wu, Yu‐Mei Xue, Li‐Chun Wang, Yang Wu

“…Background The prognostic significance of small left ventricle (LV) in the general population and its association with cardiovascular disease remain elusive. …”
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