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4521
3D-CT-derived lung volumes and mortality risk in patients with fibrotic hypersensitivity pneumonitis
Published 2025-01-01“…Background: Hypersensitivity pneumonitis (HP) is a complex and heterogenous interstitial lung disease (ILD) that occurs in susceptible individuals due to certain inhaled antigens. …”
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4522
Association between red blood cell distribution width-to-albumin ratio and all-cause mortality in intracerebral hemorrhage
Published 2025-06-01“…BackgroundIntracerebral hemorrhage (ICH) remains a devastating cerebrovascular condition, marked by high fatality and limited availability of prognostic tools. …”
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4523
Impact of Medical Conditions and Area Deprivation on Fundraising Success in Online Crowdfunding: Cross-Sectional Study
Published 2025-07-01“… Abstract BackgroundWeb-based crowdfunding is commonly used to defray medical expenses, but it is not fully known which factors determine fundraising success. …”
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4524
Impact of Additional Active Treatment for Prostate Cancer on Health-related Quality of Life of Men: Results from the EUPROMS 2.0 1-year Follow-up Survey
Published 2025-01-01“…Background and objective: In 2019 and 2021, Europa Uomo initiated the Europa Uomo Patient Reported Outcome Study (EUPROMS) and the EUPROMS 2.0 survey, with the goal of collecting data on patients’ self-reported perspective on physical and mental well-being outside of a clinical trial setting, to be able to investigate the burden of prostate cancer (PCa) treatment from a patient-to-patient perspective. …”
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4525
Systematic proteomic and small RNA profiling of extracellular vesicles from cattle infected with a naturally occurring buparvaquone-resistant strain of Theileria annulata and from...
Published 2025-06-01“…Abstract Background Extracellular vesicles (EVs) play a pivotal role in host-parasite interactions, particularly in facilitating parasite pathogenesis and immune modulation, and are crucial mediators of intercellular communication. …”
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4526
Impact of systemic immune inflammation index and systemic inflammation response index on all-cause and cardiovascular mortality in cardiovascular-kidney-metabolic syndrome
Published 2025-07-01“…Abstract Background The cardiovascular-kidney-metabolic (CKM) syndrome is a systemic condition defined by multifaceted interactions among metabolic risk factors, chronic kidney disorder, and cardiovascular diseases. …”
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4527
Atrial fibrillation or flutter in patients undergoing stem cell transplantation, in-hospital and post-discharge outcomes in a large nationwide sample across the United States
Published 2025-07-01“…Abstract Background Stem Cell Transplantation (SCT) is a cornerstone therapy in managing several malignant and benign hematological conditions. …”
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4528
Comparative cardiovascular outcomes of aripiprazole vs. risperidone in patients with type 2 diabetes and schizophrenia: a retrospective cohort study
Published 2025-07-01“…BackgroundIndividuals with schizophrenia have substantially elevated cardiovascular morbidity and mortality, a disparity further exacerbated by coexisting type 2 diabetes mellitus (T2DM). …”
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4529
Correlation of changes in inflammatory and collagen biomarkers with durable guselkumab efficacy through 2 years in participants with active psoriatic arthritis: results from a phas...
Published 2024-10-01“…Guselkumab-randomized participants with available serum biomarker data (randomly selected to reflect demographic and disease characteristics of the DISCOVER-2 population) comprised inflammatory ( N = 100) and collagen ( N = 178) biomarker cohorts. Methods: Pharmacodynamic effects of guselkumab through 2 years on inflammatory and collagen biomarker levels (general linear model) and associations between biomarkers and improvements in composite measures of joint, skin, and overall disease activity (Spearman linear regression) through 2 years were assessed. …”
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4530
HE4 as a Prognostic Biomarker of Major Adverse Cardiovascular Events in Patients with Abdominal Aortic Aneurysm: A Canadian Prospective Observational Study
Published 2025-06-01“…<b>Background:</b> Abdominal aortic aneurysm (AAA) is a chronic inflammatory disease characterized by the proteolytic breakdown of the extracellular matrix. …”
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4531
The predictive value of the serum creatinine-to-albumin ratio (sCAR) and lactate dehydrogenase-to-albumin ratio (LAR) in sepsis-related persistent severe acute kidney injury
Published 2025-01-01“…Abstract Background/objectives Sepsis-related acute kidney injury (SA-AKI) is a severe condition characterized by high mortality rates. …”
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4532
Remnant cholesterol inflammatory index, calculated from residual cholesterol to C-reactive protein ratio, and stroke outcomes: a retrospective study using the National institutes o...
Published 2025-07-01“…Abstract Background Globally, acute ischemic stroke (AIS) persists as a significant driver of both mortality and prolonged disability. …”
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4533
Infections and antibiotic resistance in Malawian children 6-59 months old hospitalized with severe acute malnutrition
Published 2025-03-01“…Background: Severe acute malnutrition (SAM) is strongly associated with mortality in young children, and infections are thought to be a major driver of that mortality. …”
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4534
Profiling of gastric cancer cell-surface markers to achieve tumour–normal discrimination
Published 2020-12-01“…However, a systematic analysis of cell-surface markers and development of a composite panel involving multiple candidates to differentiate tumour from normal has not been previously reported.Methods Whole transcriptome sequencing (WTS) of GC and matched normal samples from the Singapore Gastric Cancer Consortium (SGCC) was used as a discovery cohort to identify upregulated putative cell-surface proteins. …”
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4535
Treatment responses to Azithromycin and Ciprofloxacin in uncomplicated Salmonella Typhi infection: A comparison of Clinical and Microbiological Data from a Controlled Human Infecti...
Published 2019-12-01“…<h4>Background</h4>The treatment of enteric fever is complicated by the emergence of antimicrobial resistant Salmonella Typhi. …”
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4536
Potential Harms of Feedback After Web-Based Depression Screening: Secondary Analysis of Negative Effects in the Randomized Controlled DISCOVER Trial
Published 2025-04-01“… BackgroundWeb-based depression screening followed by automated feedback of results is frequently used and promoted by mental health care providers. …”
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4537
Translation, Cross-Cultural Adaptation, and Psychometric Validation of the Health Information Technology Usability Evaluation Scale in China: Instrument Validation Study
Published 2025-05-01“… BackgroundThe dramatic growth of digital health apps highlights an urgent need for rigorous usability evaluation tools. …”
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4538
A short-term predictive model for disease progression in acute-on-chronic liver failure: integrating spectral CT extracellular liver volume and clinical characteristics
Published 2025-03-01“…Abstract Background Acute-on-chronic liver failure (ACLF) is a life-threatening hepatic syndrome. …”
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4539
Compliance with smoke-free laws in hospitality venues in Ethiopia: A cross-sectional observational study in 10 cities.
Published 2025-01-01“…<h4>Background</h4>The 2019 Ethiopia's comprehensive tobacco control proclamation mandates 100% smoke-free public places and workplaces. …”
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4540
Modulation of Gut Microbiota through Nutritional Interventions in Behçet’s Syndrome Patients: Preliminary Results from the MAMBA Study
Published 2024-02-01“…Background. Recent evidence suggests that the gut microbiota (GM) in Behçet’s syndrome patients (BS) has low diversity and a peculiar layout. …”
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