Printable biomaterials for 3D brain regenerative scaffolds: An in vivo biocompatibility assessment by Maylis Combeau, Nina Colitti, Julien Clauzel, Franck Desmoulin, Adrien Brilhault, Juliette Fitremann, Mickaël Chabbert, Matthew L. Becker, Sébastien Blanquer, Lorenne Robert, Melissa Parny, Isabelle Raymond-Letron, Carla Cirillo, Isabelle Loubinoux

“…Developments in 3D printing offer the possibility of designing complex structures of varying compositions adapted to tissue anatomy. Methods: This feasibility study assessed the cerebral biocompatibility of four bioeliminable Digital Light Processing (DLP) printed materials in the rat model: gelatin methacrylate (GelMA), poly(ethylene glycol)diacrylate (PEGDA) mixed with GelMA (PEGDA-GelMA), poly(trimethylene carbonate) trimethacrylate (PTMC-tMA) and an ABA triblock copolymer of polypropylene fumarate-b-poly γ-methyl ε-caprolactone-b-polypropylene fumarate (P(PF-MCL-PF)). …”
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Outpatient acute kidney disease detection by national and institutional health data by Hsiu-Yin Chiang, Hung-Chieh Yeh, Zi-Han Lin, Bradley Chen, David Ray Chang, I-Wen Ting, Jie-Sian Wang, Yun-Lun Chang, Hung-Lin Chen, Yu-Chih Liu, Mei-Chuan Hsieh, Tzu-Ling Karen Tzeng, Chin-Chi Kuo

“…Abstract Background The development of diagnostic definitions for acute kidney disease in outpatients (AKDOPT) remains an unattained goal because of consensus gaps and data silos in health-care systems. …”
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Direct Oral Anticoagulants Versus Vitamin K Antagonists After Mitral Valve Transcatheter Edge‐to‐Edge Repair in Patients With Atrial Fibrillation: A Single‐Center Observational Stu... by Jan‐Hendrik Schipper, Anne‐Sophie Sommer, Richard Julius Nies, Clemens Metze, Max Maria Meertens, Jonas Wörmann, Sebastian Dittrich, Jan‐Hendrik van den Bruck, Arian Sultan, Jakob Lüker, Daniel Steven, Christopher Hohmann, Roman Pfister, Stephan Baldus, Ingo Eitel, Christian Frerker, Tobias Schmidt

“…Background Mitral valve transcatheter edge‐to‐edge repair (M‐TEER) has emerged as a viable therapy option in patients with severe mitral regurgitation and high surgical risk. …”
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Optimal Medical Therapy for Heart Failure and Integrated Care in Patients With Atrial Fibrillation: A Report From the ESC‐EHRA EORP Atrial Fibrillation Long‐Term General Registry... by Niccolò Bonini, Marco Proietti, Giulio Francesco Romiti, Marco Vitolo, Ameenathul Mazaya Fawzy, Wern Yew Ding, Jacopo Francesco Imberti, Laurent Fauchier, Francisco Marin, Michael Nabauer, Gheorghe Andrei Dan, Tatjana S. Potpara, Giuseppe Boriani, Gregory Y. H. Lip

“…Background Heart failure (HF) often occurs in patients with atrial fibrillation (AF), with a major impact on prognosis. …”
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Hypomethylating agents plus venetoclax for high-risk MDS and CMML as bridge therapy to transplant: a GESMD study by Ines Zugasti, Monica Lopez-Guerra, Sandra Castaño-Díez, Daniel Esteban, Alejandro Avendaño, Helena Pomares, Ana Perez, Sara García-Ávila, Irene Padilla Conejo, Cristina de la Fuente Montes, Alexandra Martínez-Roca, Beatriz Merchán, Carlos Jiménez-Vicente, Francesca Guijarro, Jose Ramón Álamo, Albert Cortes-Bullich, Victor Torrecillas, Lucia Mont, Esther Carcelero, Gisela Riu, Lurdes Zamora, Joan Bargay, Ana Triguero, Maria Suarez-Lledó, Maria Queralt Salas, Felix López-Cadenas, Fernando Ramos, Blanca Xicoy, David Valcárcel, Montserrat Arnan, Carmen Martínez, Montserrat Rovira, Francesc Fernández-Avilés, Maria Díez-Campelo, Jordi Esteve, Marina Díaz-Beyá

“…Abstract Background High-risk myelodysplastic syndromes (HR-MDS) and chronic myelomonocytic leukemia (CMML) remain therapeutic challenges with suboptimal outcomes. …”
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Prognosis of IgA nephropathy patient with proteinuria remission by supportive therapy: cohort from screening failed Chinese patients in TESTING study by Yingman Guo, Sufang Shi, Jinghong Zhao, Caili Wang, Zhangsuo Liu, Shuxia Fu, Nan Chen, Guisen Li, Lihua Wang, Zhaohui Ni, Haitao Zhang, Lingyun Lai, Jicheng Lv, Hong Zhang

“…Background During the run-in phase of the TESTING study, approximately half of patients with IgA nephropathy (IgAN) were excluded due to proteinuria below 1 g/24 h after intensive supportive therapy. …”
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Relationship between cognitive impairments and psychopathological symptoms in female schizophrenia subsequent to 8 weeks treatment with antipsychotic drugs by Shuzhan Gao, Qing Xu, Yanlin Han, Jing Jiang, Fan Wu, Ting Peng, Chenxi Ling, Sulin Ni, Rongrong Zhang, Yidan Ming, Xuzhen Liu, Xijia Xu

“…Abstract Background Changes in cognitive impairments and their relationship with psychopathological symptoms during treatment in schizophrenia remain debatable. …”
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Remnant–to–LDL cholesterol discordance as a predictor of thromboembolic events in anticoagulated patients with atrial fibrillation: a report from the prospective Murcia AF project... by Eva Soler-Espejo, Yang Chen, José Miguel Rivera-Caravaca, María Pilar Ramos-Bratos, Raquel López-Gálvez, Francisco Marín, Vanessa Roldán, Gregory Y.H. Lip

“…Abstract Background Remnant cholesterol (RC) has emerged as an independent contributor to residual cardiovascular risk, beyond low-density lipoprotein cholesterol (LDL-C). …”
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Initial Clinical Experience with the Biodegradable AbsnowTM Device for Percutaneous Closure of Atrial Septal Defect: A 3-Year Follow-Up by Yifan Li, Yumei Xie, Boning Li, Zhaofeng Xie, Junjun Shen, Shushui Wang, Zhiwei Zhang

“…Methods. Five pediatric patients were enrolled from May to June 2018 in our institution and were followed up for 3 years. …”
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Unveiling the potentials of Lawsonia inermis L.: its antioxidant, antimicrobial, and anticancer potentials by Nantikan Joyroy, Lukana Ngiwsara, Siriporn Wannachat, Ratchanee Mingma, Jisnuson Svasti, Jintanart Wongchawalit

“…Background Lawsonia inermis L., commonly known as henna, is a traditional medicinal Indian plant used for anti-dandruff and antifungal purposes. …”
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The effect of α-lipoic acid treatment on plasma asymmetric dimethylarginine, a biomarker of endothelial dysfunction in diabetic neuropathy by Ferenc Sztanek, Hajnalka Lőrincz, Ágnes Molnár, Anita Szentpéteri, Eszter Zöld, Ildikó Seres, Dénes Páll, Mariann Harangi, Péter Kempler, György Paragh

“…Introduction Diabetic neuropathy may develop on a background of hyperglycaemia and is associated with increased oxidative stress. …”
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Oxidative balance score predicts chronic kidney disease risk in overweight adults: a NHANES-based machine learning study by Leying Zhao, Leying Zhao, Cong Zhao, Cong Zhao, Yuchen Fu, Yuchen Fu, Xiaochang Wu, Xiaochang Wu, Xuezhe Wang, Xuezhe Wang, Yaoxian Wang, Yaoxian Wang, Yaoxian Wang, Huijuan Zheng

“…BackgroundOxidative stress plays a pivotal role in the pathogenesis of chronic kidney disease (CKD), particularly in overweight and obese populations where adipose tissue dysfunction exacerbates systemic inflammation and metabolic derangements. …”
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Short- and mid-term outcomes after redo surgical valve replacement by Pardis Sadeghi, Ali Hosseinsabet, Reza Mohseni-Badalabadi, Arash Jalali, Ahmad Vakili-Basir, Mina Pashang, Negar Omidi, Jamshid Bagheri, Mohammadjavad Mehrabanian

“…Abstract Background While previous studies have indicated comparable outcomes for redo surgical valve replacement (SVR) and primary SVR, there is limited information regarding the long-term follow-up of these patients. …”
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Diastolic function and cardiovascular events in patients with preserved left ventricular ejection fraction. Improving risk stratification with left atrial strain by Ibon Rodriguez-Sanchez, Inaki Villanueva-Benito, Urko Agirre, Jose Juan Onaindia, Alazne Urkullu, Angela Cacicedo, Alberto Ullate, Idoia Bravo, Josu Florido, Alberto Salcedo, Sonia Velasco

“…BackgroundA limited number of studies have examined the prognostic significance of diastolic function in patients with preserved left ventricular ejection fraction (LVEF) in a general population referred for transthoracic echocardiography. …”
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Effect of Frailty on Cardiovascular Clinical Trials by Haowen Jiang, MBBS, Jie Jun Wong, MBBS, Ru-San Tan, MBBS, Fei Gao, PhD, Louis LY. Teo, MBBS, Jordan B. Strom, MD, MSc, Chim C. Lang, MD, PhD, Angela S. Koh, MBBS, MPH, PhD

“…Background: Patients with cardiovascular (CV) diseases are increasingly frail but rarely represented in trials. …”
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Comparative assessment of line probe assays and targeted next-generation sequencing in drug-resistant tuberculosis diagnosisResearch in context by Giovanna Carpi, Marva Seifert, Andres De la Rossa, Swapna Uplekar, Camilla Rodrigues, Nestani Tukvadze, Shaheed V. Omar, Anita Suresh, Timothy C. Rodwell, Rebecca E. Colman

“…Summary: Background: Rapid and accurate detection of drug-resistant tuberculosis (DR-TB) is crucial for ensuring effective treatment, halting transmission and preventing the amplification of resistance. …”
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Retrospective assessment of clinical global impression of severity and change in GM1 gangliosidosis: a tool to score natural history data in rare disease cohorts by Connor J. Lewis, Jean M. Johnston, Silvia Zaragoza Domingo, Gilbert Vezina, Precilla D’Souza, William A. Gahl, David A. Adams, Cynthia J. Tifft, Maria T. Acosta

“…Abstract Background Clinical trials for rare diseases pose unique challenges warranting alternative approaches in demonstrating treatment efficacy. …”
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Long-term cancer risk in users of GLP-1 agonists in Denmark: a nationwide emulated trialResearch in context by Mads Gamborg, Mia Klinten Grand, Kathrine Grell, Susanne Rosthøj, Ulrik Pedersen-Bjergaard, Christian Torp-Pedersen, Lina Steinrud Mørch

“…Summary: Background: The long-term cancer safety of glucagon-like peptide-1 receptor agonists (GLP-1RAs) in real-world settings remains unclear, with limited long-term clinical and observational studies. …”
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Spatial distribution and urban–rural disparity of unmet need for family planning among married/in-union women in Ethiopia: a spatial and decomposition analysis by Shimels Derso Kebede, Daniel Niguse Mamo, Jibril Bashir Adem, Agmasie Damtew Walle, Yawkal Tsega, Elsabeth Addisu, Zinabu Bekele Tadese, Ermias Bekele Enyew

“…BackgroundHigh unmet need for family planning combined with other factors, such as high early marriage and teenage pregnancy, increases the risk of developing obstetric fistula and other complications. …”
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Risk of mental health conditions in bereavement: a population-based analysis of lung cancer spouses by Djin L. Tay, Kline Dubose, Kline Dubose, Jonathan Chipman, Jonathan Chipman, Lee Ellington, Malek Alnajar, Eli Iacob, Caroline Stephens, Katherine A. Ornstein

“…BackgroundCaregiving to lung cancer patients is distressing, isolating, and associated with a high burden of anxiety and depression. …”
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