Using Social Media Platforms to Raise Health Awareness and Increase Health Education in Pakistan: Structural Equation Modeling Analysis and Questionnaire Study by Malik Mamoon Munir, Nabil Ahmed

“… Abstract BackgroundCurrent health care education methods in Pakistan use traditional media (eg, television and radio), community health workers, and printed materials, which often fall short of reach and engagement among most of the population. …”
Get full text

An Explainable Artificial Intelligence Text Classifier for Suicidality Prediction in Youth Crisis Text Line Users: Development and Validation Study by Julia Thomas, Antonia Lucht, Jacob Segler, Richard Wundrack, Marcel Miché, Roselind Lieb, Lars Kuchinke, Gunther Meinlschmidt

“… BackgroundSuicide represents a critical public health concern, and machine learning (ML) models offer the potential for identifying at-risk individuals. …”
Get full text

Technological dental sealants: in vitro evaluation of material properties and antibiofilm potential by Witalo Pereira de Jesus, Luiza de Almeida Queiroz Ferreira, Washington Henrique Themoteo da Silva, Fernanda Vieira Belém, Ana Paula Turrioni, Cláudia Silami de Magalhães, Mila Fernandes Moreira Madeira, Ivana Márcia Alves Diniz, Marco Aurelio Benini Paschoal

“…Abstract Background Due to the launch of new self-etching and self-adhesive sealing materials combined with the release of bioactive ions in the dental market, this in vitro study aimed to compare physical values of surface roughness (RS), vickers microhardness (VM), compositional energy dispersive spectroscopy (EDS), scanning electron microscopy (SEM), microbiological tests (inhibition halo-HI and surface microbial adhesion-MAS) and mechanical microshear bond strength (MBS). …”
Get full text

The Role of Glycemic Control in Inflammation Markers and Clinical Outcomes in Type 2 Diabetes Patients with Severe COVID-19 by Lavinia Craciun, Flavia Ignuta, Uma Shailendri Rayudu, Maliha Afra, Ovidiu Rosca, Adrian Vlad, Oana Aburel, Dana Emilia Velimirovici

“…<b>Background and Objectives:</b> Patients with type 2 diabetes mellitus (T2DM) are at a heightened risk of adverse outcomes from Coronavirus Disease 2019 (COVID-19). …”
Get full text

Ganoderma lucidum spore oil alleviates psychological stress-evoked tumor progression by enhancing FcγR-mediated macrophage phagocytosis by Dong-Dong Li, Zi-Xuan Li, Yang-Fan Zhou, Ling Jin, Wan-Li Liang, Wen-Dong Xu, Xiang Luo, Guan-Di Xiao, Qi-Jun Chen, Ting Xie, Hui Xu, Yang Liu, Hong-Fei Cai, Yun-Feng Cao, Wan-Yang Sun, Yi-Fang Li, Lei Liang, Ju-Yan Liu, Yan-Ping Wu, Rong-Rong He

“…Abstract Background Ganoderma lucidum (G. lucidum), has been documented as a medicinal herb in classical texts and officially recognized in both Eastern and Western pharmacopeias. …”
Get full text

Muscle-building interventions improve glucose metabolism in elderly type 2 diabetic patients with sarcopenic obesity by Tingting Han, Xinyue Liang, Hongxia Liu, Mingyu Zhu, Sisi Shen, Jia Song, Hongwei Chen, Ningxin Chen, Yue Liu, Ziyi Wei, Yurong Weng, Xian Jin, Yaomin Hu

“…Abstract Background Among all the elderly patients with type 2 diabetes mellitus (T2DM) of different body compositions, patients with sarcopenic obesity exhibited the most severe degree of insulin resistance despite possessing a normal body weight. …”
Get full text

Cerebrovascular Disease Detected on Preprocedural Computed Tomography in Patients With Severe Aortic Stenosis Undergoing Aortic Valve Replacement by Ko Yamamoto, Hiroyuki Ueda, Daiji Uchiyama, Yasuaki Takeji, Tomohiko Taniguchi, Takeshi Morimoto, Hiroyuki Tabata, Kenichi Ishizu, Toru Morofuji, Masaomi Hayashi, Akihiro Isotani, Shinichi Shirai, Nobuhisa Ohno, Shinichi Kakumoto, Kenji Ando, Kenji Minatoya, Takeshi Kimura

“…Background There is a scarcity of data on the prevalence and clinical impact of cerebrovascular disease detected on preprocedural computed tomography (CT) before aortic valve replacement (AVR) in patients with severe aortic stenosis. …”
Get full text

Association of body mass index and outcomes in surgical and transcatheter aortic valve replacement by Bennet S. Cho, MD, Troy N. Coaston, BS, Amulya Vadlakonda, BS, Sara Sakowitz, MPH, MS, Syed Shaheer Ali, Esteban Aguayo, MD, Peyman Benharash, MD

“…Background: The association between body mass index (BMI) and outcomes in surgical aortic valve replacement (SAVR) and transcatheter aortic valve replacement (TAVR) is not well understood. …”
Get full text

The perceived workload of first-line healthcare professionals during neonatal resuscitation by Hai-Bo Huang, Kui Sang, Ming Zhou, Lin Yi, Jiang-Qin Liu, Chuan-Zhong Yang, Brenda H.Y. Law, Georg M. Schmölzer, Po-Yin Cheung

“…Background: Neonatal resuscitation is stressful for healthcare professionals as measured using the National Aeronautics and Space Administration-Task Load Index (NASA-TLX). …”
Get full text

Exercise Right Ventricular‐Pulmonary Arterial Coupling and Functional Outcome in Patients Undergoing Surgery for Secondary Ischemic Mitral Regurgitation by Carlo Fino, Diego Bellavia, Michele D'Alonzo, Maurizio Merlo, Vito D. Bruno, Julien Magne, Massimo Caputo, Amedeo Terzi, Michele Senni, Samuele Bichi, Caterina Simon, Edoardo Sciatti, Giovanni Marchetto, Attilio Iacovoni, Philippe Pibarot

“…Background The exercise assessment of the right ventricular‐pulmonary arterial (PA) coupling adds diagnostic and prognostic value in patients with heart failure. …”
Get full text

Effect of individualized versus conventional perioperative blood pressure management on postoperative major complications in high-risk patients undergoing noncardiac surgery: study... by Jaeyeon Chung, Chang-Hoon Koo, Jungchan Park, Hye-Bin Kim, Jinyoung Bae, Jae-Woo Ju, Soowon Lee, Ah Ran Oh, Hyo Sung Kim, Soo Jung Park, Yunseok Jeon, Karam Nam, for the Seoul PeRioperative OUTcome research-4 (SPROUT-4) Investigators

“…Abstract Background Intraoperative hypotension is very common during surgery and is linked to major organ dysfunction and mortality. …”
Get full text

Hand dexterity and mobility independently predict cognition in older adults: a multi-domain regression analysis by Thomas Rudolf Schneider, Ansgar Felbecker, Ansgar Felbecker, Ben von Mitzlaff, Ben von Mitzlaff, Gregor Weissofner, Gregor Weissofner, Sarah Meier, Sarah Meier, Patrick Eggenberger, Patrick Eggenberger, Patrick Eggenberger, Simon Annaheim

“…BackgroundMotor function is a sensitive indicator of cognitive aging but the unique contributions of different motor domains are unclear when assessed together.MethodsWe evaluated 98 community-dwelling older adults (median age: 74). …”
Get full text

Real-Time ConvNext-Based U-Net with Feature Infusion for Egg Microcrack Detection by Chenbo Shi, Yuejia Li, Xin Jiang, Wenxin Sun, Changsheng Zhu, Yuanzheng Mo, Shaojia Yan, Chun Zhang

“…Furthermore, on the publicly benchmarked CrackSeg9k dataset, CBU-FI Net achieves an inference speed of 4 ms for 400 × 400 resolution images, with an MIoU of 81.38%, proving the proposed method’s robustness and generalization capability across various cracks and complex backgrounds.…”
Get full text

Multi‐Trait Polygenic Risk Score, Nongenetic Determinants, and Cardiovascular Disease Death: A Cohort Study of 14 086 Japanese Individuals by Ryosuke Fujii, Mako Nagayoshi, Masahiro Nakatochi, Shuntaro Sato, Yoshiki Tsuboi, Koji Suzuki, Hiroaki Ikezaki, Yuichiro Nishida, Yoko Kubo, Shiroh Tanoue, Sadao Suzuki, Teruhide Koyama, Kiyonori Kuriki, Naoyuki Takashima, Sakurako Katsuura‐Kamano, Yukihide Momozawa, Kenji Wakai, Keitaro Matsuo

“…Background Although utility of composite trait‐specific polygenic risk score (multi‐trait PRS) has been examined among European ancestries, few studies investigated among East Asians and incorporated modifiable risk factors. …”
Get full text

Association of habitual glucosamine use with risk of microvascular complications among individuals with type 2 diabetes: a prospective cohort study in UK biobank by Zi-Jian Cheng, Yu-feng Luo, Qing-yun Zhu, Yan-fei Wang, Wen-yan Ren, Fei-yan Deng, Lin Bo, Xi-Yuan Jiang, Shu-feng Lei, Long-Fei Wu

“…Abstract Background Glucosamine is a widely used supplement for treating osteoarthritis and joint pain. …”
Get full text

Impact of Procedural Success Definitions on Long‐Term Outcomes in Patients With Rheumatic Mitral Stenosis Treated With Percutaneous Balloon Mitral Valvuloplasty: A Multicenter, Ret... by Premanan Manoret, Tasalak Thonghong, Krissada Meemook, Seththawut Kosallavat, Suchart Aroonsiriwattana, Thammarak Songsangjinda, Saranyou Suwanugsorn, Thanapon Nilmoje, Sirichai Cheewatanakornkul, Treechada Wisaratapong, Sunti Limumpornpetch, Watchara Lohawijarn, Metus Thungthienthong, Noppadol Chamnarnphol, Mann Chandavimol, Pannipa Suwannasom, Woravut Jintapakorn, Ply Chichareon

“…Background It is uncertain which percutaneous balloon mitral valvuloplasty (PBMV) success definitions should be used because there are no studies comparing the effects of these definitions on subsequent outcomes. …”
Get full text

General anesthesia is an independent predictor for worse maternal outcome in pregnant pulmonary arterial hypertension patients without cardiac shunt but not for those with shunt by Weida Lu, Min Li, Fuqing Ji, Hua Feng, Liangyi Qie, Guo Li, Qiushang Ji, Mingying Ling, Fan Jiang, Xiaopei Cui

“…Abstract. Background. Although pregnancy imposes extra risk in patients with pulmonary arterial hypertension (PAH), hemodynamic characteristics vary between PAH patients with and without cardiac shunts. …”
Get full text

New prognostic index for neoadjuvant chemotherapy outcome in patients with advanced high-grade serous ovarian cancer by Chuying Huo, Bin Wu, Dongdong Ye, Miaochun Xu, Shaolin Ma, Aoshuang Cheng, Yunyun Liu, Chunxian Huang, Yuhao Zhang, Zhongqiu Lin, Bowen Li, Huaiwu Lu

“…Abstract Background A validated prognostic index for the outcome of patients with advanced high-grade serous ovarian cancer (HGSOC) undergoing neoadjuvant chemotherapy (NACT) remains elusive. …”
Get full text

Do collaterals to infarct bed in STE-ACS patients undergoing emergent percutaneous coronary revascularization matter? An assessment of a prospective pool for in-hospital course by Rajesh Kumar, Naveed Ullah Khan, Ayaz Mir, Khalid Naseeb, Gulzar Ali, Arti Ashok, Mukesh Kumar, Abiha Urooj, Uroosa Safdar, Aisha Hussain, Muhammad Ishaq, Tahir Saghir, Jawaid Akbar Sial, Abdul Hakeem, Musa Karim

“…Background: Limited data exist on the role of coronary collaterals circulation (CCC) in patients with ST-elevation acute coronary syndrome (STE-ACS). …”
Get full text

Biotechnology Production of Cell Biomass from the Endangered <i>Kickxia elatine</i> (L.) Dumort: Its Untargeted Metabolomic Analysis and Cytotoxic Potential Against Melanoma Cells by Anastasia Aliesa Hermosaningtyas, Ewa Totoń, Anna Budzianowska, Natalia Lisiak, Aleksandra Romaniuk-Drapała, Dariusz Kruszka, Monika Rewers, Małgorzata Kikowska

“…<b>Background:</b> Melanoma is a malignant tumor of melanocytes with an increasing incidence worldwide. …”
Get full text