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4421
A sustainable organizational structure to integrate psycho-social stimulation programme into primary health care services in Bangladesh: protocol for a pragmatic cluster randomized...
Published 2025-05-01“…Abstract Background Early childhood development (ECD) in low to middle-income nations has been a pressing concern for the last two to three decades. …”
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4422
Characteristics and prognosis of language impairment in subcortical aphasia of acute stroke patients
Published 2025-07-01“…BackgroundSubcortical aphasia, caused by lesions in deep brain structures such as the basal ganglia, thalamus, and periventricular white matter, remains poorly understood due to its heterogeneous clinical presentations and disputed neural mechanisms. …”
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4423
Exploration of mortality-associated creatinine thresholds for acute kidney injury in cardiac surgery patients with impaired kidney function: a single-center retrospective cohort st...
Published 2025-07-01“…Abstract Background Acute kidney injury (AKI) is a frequent and severe complication following cardiac surgery, particularly in patients with impaired kidney function. …”
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4424
Long-term trajectories of apolipoprotein A1 and major adverse cardiovascular events and mortality in a community cohort
Published 2025-04-01“…Abstract Background Apolipoprotein A1 (ApoA1) is a major component of high-density lipoprotein cholesterol and plays a critical role in reverse cholesterol transport. …”
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4425
Tobacco Use, Risk Perceptions, and Characteristics of Adults Who Used a Heated Tobacco Product (IQOS) in the United States: Cross-Sectional Survey Study
Published 2025-02-01“… BackgroundThe Tobacco Heating System (THS; commercialized as IQOS) is a smoke-free heated tobacco product introduced in the United States in 2019 and authorized by the US Food and Drug Administration as a modified risk tobacco product (MRTP) in 2020. …”
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4426
Associations between non-insulin-based insulin resistance surrogate markers and liver-related outcomes in metabolic dysfunction-associated steatotic liver disease: a nationwide coh...
Published 2025-04-01“…Abstract Background Insulin resistance (IR) is a crucial mechanism in the pathogenesis and clinical progression of metabolic dysfunction-associated steatotic liver disease (MASLD). …”
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4427
Association of C-reactive protein-triglyceride glucose index with the incidence and mortality of cardiovascular disease: a retrospective cohort study
Published 2025-08-01“…Abstract Background The C-reactive protein-triglyceride-glucose index (CTI) has emerged as an innovative composite marker for evaluating metabolic-inflammatory dysregulation, integrating markers of insulin resistance and systemic inflammation. …”
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4428
Associations of non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio with diabetes and prediabetes among adults with hypertension: a cross-section...
Published 2025-05-01“…BackgroundThe non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (NHHR) is an emerging composite lipid marker. …”
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4429
Effect of radiation therapy on the dentin bond strength of a universal adhesive
Published 2025-05-01“…Abstract Background Successful restorative procedures, particularly for patients undergoing head and neck radiotherapy, rely on a robust adhesive interface. …”
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4430
Blood pressure-lowering treatment for the prevention of cardiovascular events in patients with atrial fibrillation: An individual participant data meta-analysis.
Published 2021-06-01“…<h4>Background</h4>Randomised evidence on the efficacy of blood pressure (BP)-lowering treatment to reduce cardiovascular risk in patients with atrial fibrillation (AF) is limited. …”
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4431
The Association Between Neonatal Respiratory Distress Syndrome and Plasma IgG N-Glycosylation: A Case-Control Study
Published 2025-05-01“…However, its implications and clinical significance in NRDS remain to be clarified.Methods: To determine the effect of IgG N-glycosylation on NRDS, we recruited 88 NRDS participants and 120 control participants from December 2021 to September 2022. …”
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4432
First-in-human implementation of a bidirectional somatosensory neuroprosthetic system with wireless communication
Published 2025-04-01“…Abstract Background Limitations in upper limb prosthesis function and lack of sensory feedback are major contributors to high prosthesis abandonment rates. …”
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4433
Two-Year Longitudinal Motor Performance of Very Preterm and/or Very-Low-Birth-Weight Infants in Suriname
Published 2025-03-01“…Very preterm infants (gestational age < 32 weeks and/or very-low-birth-weight < 1500 g) in the middle-income country of Suriname were included. <b>Methods:</b> We assessed 149 (49.7% boys) infants (mean gestational age 29<sup>+6</sup>, mean birth weight 1271 g) at 3, 12, and 24 months with the Bayley Scales of Infant and Toddler Development for fine motor (FM), gross motor (GM), and composite scores (CSs). …”
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4434
Association of Conventional and Unconventional Lipid Profiles with Visceral Fat Area in Overweight/Obese Individuals with Type 2 Diabetes Mellitus
Published 2025-04-01“…Emphasizing the overall relationship between lipid metabolism and visceral fat accumulation.Methods: This cross-sectional study included 1288 overweight/obese T2DM patients, with VFA measured using bioelectrical impedance analysis and visceral fat obesity (VFO) was defined as VFA ≥ 100 cm². …”
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4435
The association between oxidative balance scores and all-cause mortality and cancer-specific mortality in cancer survivors: a retrospective cohort study
Published 2025-05-01“…BackgroundNumerous studies have established that oxidative stress significantly affects the long-term survival of cancer survivors. …”
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4436
Suicidal ideation, attempt and associated factors among adult cancer patients at Jimma University Medical Center, Jimma, Ethiopia, 2023
Published 2025-03-01“…BackgroundCancer has been associated with an increased risk of suicidal behaviors and suicide has been one of the leading causes of non-cancer-related mortality among cancer patients in recent years. …”
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4437
Reproductive agency and the acceptability of divorce, abortion, and homosexuality among migrants from the Middle East and Africa living in Sweden–a cross-sectional analysis
Published 2025-02-01“…Abstract Background Sweden has a longstanding history of promoting sexual reproductive health and rights. …”
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4438
Nuclear factor κ-B is activated in the pulmonary vessels of patients with end-stage idiopathic pulmonary arterial hypertension.
Published 2013-01-01“…<h4>Objectives</h4>To assess activation of the inflammatory transcription factor NF-kappa B (NF-κB) in human idiopathic pulmonary arterial hypertension (PAH).<h4>Background</h4>Idiopathic PAH is a severe progressive disease characterized by pulmonary vascular remodeling and excessive proliferation of vascular cells. …”
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4439
Genetic and transcriptional insights into immune checkpoint blockade response and survival: lessons from melanoma and beyond
Published 2025-04-01“…Abstract Background Integration of immune checkpoint inhibitors (ICIs) with non-immune therapies relies on identifying combinatorial biomarkers, which are essential for patient stratification and personalized treatment. …”
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4440