Rationale and design of randomized non-inferiority clinical trial to compare the safety and efficacy of ticagrelor monotherapy with dual antiplatelet therapy in chronic coronary sy... by Seyed Alireza Mirhosseini, Mohammadreza Akbari, Davar Aldavood, Hooyar Zarifkar, Armin Attar, Javad Kojuri

“…<h4>Background</h4>Despite the wide variety of antiplatelet regimens and durations, the optimal treatment approach for chronic coronary syndrome (CCS) patients remains a subject of ongoing debate. …”
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A randomized multicenter trial comparing the XIENCE everolimus eluting stent with the CYPHER sirolimus eluting stent in the treatment of female patients with de novo coronary arter... by Anna Franzone, Serge Zaugg, Raffaele Piccolo, Maria Grazia Modena, Ghada W Mikhail, Josepa Mauri Ferré, Ruth Strasser, Liliana Grinfeld, Dik Heg, Peter Jüni, Stephan Windecker, Marie-Claude Morice

“…<h4>Background</h4>The comparative performance of different drug-eluting stents (DES) among female patients has not been assessed in a randomized manner.…”
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Correlation between stress hyperglycemia ratio and prognosis in acute myocardial infarction patients following percutaneous coronary intervention by Wei Meng, Hui Qiu, Weiping Li, Weiping Li, Weiping Li, Hongwei Li, Hongwei Li, Hongwei Li

“…BackgroundStress hyperglycemia ratio (SHR) is a commonly used predictor of acute hyperglycemia. …”
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Cerebrospinal fluid (CSF) CD8+ T-cells that express interferon-gamma contribute to HIV associated neurocognitive disorders (HAND). by Rachel D Schrier, Suzi Hong, Melanie Crescini, Ronald Ellis, Josué Pérez-Santiago, Celsa Spina, Scott Letendre, HNRP Group

“…<h4>Background</h4>HIV associated neurocognitive disorders (HAND) continue to affect cognition and everyday functioning despite anti-retroviral treatment (ART). …”
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Combined systemic immune-inflammatory index and prognostic nutritional index predicts the efficacy and prognosis of ES-SCLC patients receiving PD-L1 inhibitors combined with first-... by Yi Ge, Xiaoyu Liu, Yishi Xu, Yanwei Su, Yixin Li, Liping Wang

“…BackgroundThere is a strong association between inflammation and the formation, progression, and metastasis of malignant tumors, according to earlier studies. …”
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Phase‐Specific Hemodynamic Criteria and Outcomes in Patients With Cardiogenic Shock Receiving Percutaneous Ventricular Assist Devices by Yuki Ikeda, Keita Saku, Jun Nakata, Takashi Unoki, Takeshi Yamamoto, Tomohiro Sakamoto, Junya Ako

“…Background Standardized protocols with optimal hemodynamic targets for percutaneous ventricular assist device (PVAD) management remain undefined. …”
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Intrinsic capacity trajectories and cardiovascular disease incidence among Chinese older adults: a population-based prospective cohort study by Zhiting Guo, Yuling Chen, Binu Koirala, Jiaying Li, Yingying Jia, Cheryl R. Dennison Himmelfarb, Jingfen Jin

“…Abstract Background Intrinsic capacity (IC), a composite of physical and mental capacities, is a marker of healthy aging. …”
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Predictive value of systemic immune inflammation index combined with coagulation index in traumatic coagulopathy in patients with severe trauma by Chen Wang, Yongyong Huang, Shiyun Liao, Jiming Song

“…Background: Traumatic coagulopathy (TIC) poses a significant challenge in the management of severe trauma cases. …”
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Relationship Between the ZJU Index and Infertility Risk in Reproductive-Aged US Women: An Analysis of NHANES 2013&amp;ndash;2018 by Tian L, Qin X, Yang M, Tang W, Feng L, Huang J, Hu H

“…Ling Tian,1,&amp;ast; Xiangzhi Qin,2,&amp;ast; Mingtao Yang,1 Wen Tang,1 Lu Feng,1 Junrong Huang,1 Huiquan Hu1 1Department of Gynaecology, Beijing Anzhen Nanchong Hospital, Capital Medical University &amp; Nanchong Central Hospital, Nanchong, People’s Republic of China; 2Department of Gastrointestinal Hernia Surgery, Beijing Anzhen Nanchong Hospital, Capital Medical University &amp; Nanchong Central Hospital, Nanchong, People’s Republic of China&amp;ast;These authors contributed equally to this workCorrespondence: Huiquan Hu, Email 36311773@qq.comBackground: The ZJU index is a composite metabolic score that integrates blood glucose, body mass index (BMI), liver enzyme ratios (ALT/AST), and triglyceride levels, originally developed to predict non-alcoholic fatty liver disease. …”
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Clustering-aided prediction of outcomes in patients with idiopathic pulmonary fibrosis by Lijun Wang, Peitao Wu, Yi Liu, Divya C Patel, Thomas B Leonard, Hongyu Zhao

“…Abstract Background Blood biomarkers predictive of the progression of idiopathic pulmonary fibrosis (IPF) would be of value for research and clinical practice. …”
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The INFLUENCE OF NUTRITION ON DISEASE SEVERITY AND HEALTH-RELATED QUALITY OF LIFE IN ADULTS WITH SICKLE CELL DISEASE by Sanaa Kamal, Moheyeldeen Mohamed Naghib, Jamaan Al Zahrani, Huda Hassan, Karim Abdel Aziz Moawado, Omar Arrahman

“…Background & Aims: Sickle cell disease (SCD has a worldwide distribution and causes significant morbidity and mortality in children and adults. …”
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Improved Biological Impacts of Anti-EGFR Monoclonal Antibody in KRAS-Mutant Colorectal Cancer Cells by Silica-Coated Magnetic Nanoparticle Conjugation by Maedeh Yousefi, Hamed Farzi-Khajeh, Mostafa Akbarzadeh-Khiavi, Azam Safary, Khosro Adibkia

“…Background: The therapeutic potential of epidermal growth factor receptor (EGFR) targeting in colorectal cancer (CRC) is hindered by the presence of KRAS codon 12 activating mutations, prevalent in approximately 25% of advanced CRC cases. …”
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Advances in research on noble gas as tracers of geofluids and helium enrichment by Yu GAO, Quanyou LIU, Dongya ZHU, Xiaoqi WU, Pengpeng LI

“…BackgroundNoble gases emerge as significant tools for tracing the sources and evolutionary processes of geofluids due to their chemical inertness and different isotopic compositions across varying reservoirs. …”
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Confirmatory Factor Analysis and Propensity to Cheat Scale Validation in the Ethiopian Public Higher Education Institutions [version 3; peer review: 1 approved, 2 approved with res... by Tesfaye Semela, Samuel Assefa, Dame Taye

“…Background This study aimed to validate a comprehensive and psychometrically sound instrument—the Propensity to Cheat Scale (PCS)—designed to measure undergraduate students’ propensity toward academic dishonesty in Ethiopian universities. …”
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Effect of gender and training years on the upper extremity dynamic balance function in adolescent swimmers by Zi-An Lu, Zhao-Feng Lv, Qi-Hao Yang, Shu-Hao Du, Yu-Chen Wang, Yong-Hui Zhang

“…Abstract Background Upper extremity dynamic balance is the ability of the upper extremities to sustain stability during exercise. …”
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Combined impact of prediabetes and fatty liver index on cardiometabolic outcomes and mortality in middle aged adults: a nationwide cohort study by Young Sang Lyu, Minae Park, Hee Kyung Kim, Sojeong Park, Ji Yong Park, A Ram Hong, Jee Hee Yoon, Seogsong Jeong, Youngmin Yoon, Jin Hwa Kim, Sang Yong Kim, Ho-Cheol Kang, Wonsuk Choi

“…Abstract Background To investigate the combined effect of prediabetes and fatty liver index on incident diabetes (DM), major adverse cardiovascular events (MACE), and mortality in middle-aged adults. …”
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Assessment of health status and quality of life of homeless persons in Belgrade, Serbia by Sarajlija Marija, Jugović Aleksandar, Živaljević Dragan, Merdović Boro, Sarajlija Adrijan

“…Background/Aim. Homelessness is a problem with social, medical, economic, political and other implications. …”
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Primary thromboprophylaxis in ambulatory symptomatic patients with COVID-19: a systematic review and meta-analysis of randomized controlled trials by Davide Di Vece, Marco Valgimigli, Elliot Barnathan, Jean M. Connors, Frank Cools, Ulrike Held, Ajay K. Kakkar, Gregory Piazza, David Spirk, Saverio Virdone, Nils Kucher, Stefano Barco

“…Background: The global impact of the COVID-19 pandemic has prompted the search for strategies to improve outcomes in affected individuals, including those initially managed in outpatient settings. …”
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Procollagen type 1 N-terminal propeptide is associated with adverse outcome in acute chest pain of suspected coronary origin by Thomas Andersen, Thomas Andersen, Thor Ueland, Thor Ueland, Thor Ueland, Pål Aukrust, Pål Aukrust, Pål Aukrust, Dennis W.T. Nilsen, Dennis W.T. Nilsen, Heidi Grundt, Heidi Grundt, Harry Staines, Volker Pönitz, Frederic Kontny, Frederic Kontny

“…BackgroundExtracellular matrix (ECM) is an integral player in the pathophysiology of a variety of cardiac diseases. …”
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Outcomes for older people with screening-detected versus existing chronic kidney disease: a cohort study with data linkage by Anna K Forbes, José M Ordóñez-Mena, Winnie Mei, Clare J Taylor, Nicholas Jones, Jennifer A Hirst, FD Richard Hobbs

“…Design & setting: Prospective cohort study of 892 primary care patients aged ≥60 years with CKD (existing and screening detected) in Oxfordshire, with data linkage to civil death registry and secondary care. Method: Hazard ratios (HRs) and 95% confidence intervals (CIs) were estimated using Cox proportional hazard models to compare the risk of all-cause mortality, hospitalisation, CVD, ESKD separately, and as a composite between CKD groups, as well as to identify factors associated with mortality. …”
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