Oxidative balance score and mortality: mediating role of insulin resistance across age strata in the NHANES cohort by Lin Zhang, Lin Zhang, Heming Zhang, Heming Zhang, Hongxia Xiang, Jiachen Zhang, Wei Gong, Junjie Xv, Xue Yu

“…BackgroundThis study examined the association between oxidative balance score (OBS), a composite measure of oxidative/antioxidative factors, and mortality, while investigating insulin resistance (IR) indices as potential mediators using a nationally representative cohort.MethodsA cohort of 11,849 U. …”
Get full text

Dermal Substitute Integra for the Treatment of Mammalian Bite Injuries of Nose: a New Reconstructive Ladder by Ilaria Mataro, MD, Santolo D’Antonio, MD, Matteo D’Alessio, MD, Carlo Petroccione, MD, Dario D’Angelo, MD, Simone La Padula, MD, Roberto D’Alessio, MD, Stefano Avvedimento, MD

“…Background:. Bite injuries affecting the nose are uncommon occurrences characterized by their intricate nature and potential for severe complications. …”
Get full text

Volatile Compounds in Musk and Their Anti-Stroke Mechanisms by Chengli Zheng, Xin Shi, Qinling Yang, Zhongkun Cai, Xiao Wang, Liuqing Yang, Xue Bai, Xiuxiang Meng, Diyan Li, Hang Jie

“…<b>Background/Objectives:</b> Musk is a widely used traditional Chinese medicine derived from musk deer that has the pharmacological effects of “activating blood dredging collateral” and “consciousness-restoring resuscitation”. …”
Get full text

Long-term prognostic value of CRP–albumin–lymphocyte index in elderly patients with heart failure with preserved ejection fraction by Qingwei He, Yukun Cao, Xingman Fan, Bowen Li, Qiongyi He, Haitao Zhang

“…Background: Heart failure with preserved ejection fraction (HFpEF) is a complex and heterogeneous clinical condition characterized by the interplay of malnutrition and immune inflammation, especially in elderly patients. …”
Get full text

Safety and efficacy of sirolimus combined with cyclosporine in primary membranous nephropathy: a randomized controlled trial by Fang Wang, Chao Yang, Yue Shu, Cai-xia Lin, Yao Yao, Yue Li, Yi-miao Zhang, Xin Wang, Li-qiang Meng, Xu-yang Cheng, Gang Liu, Ming-hui Zhao, Zhao Cui

“…Abstract Background Calcineurin inhibitors, such as cyclosporine, are primary treatments for membranous nephropathy (MN). …”
Get full text

Framing of Oil Spillage and Gas Flaring in Rivers State in Three Selected Nigerian Newspapers by Ata-Awaji Reuben, Nyerhovwo MUOBOGHARE, Bassey IKOT-OSIN, Soibi ORUWARI, Etimbuk OBOT, Emmanuel Omula, Theresa LINUS, Peace OJONTA, Simon SHEYIGARI

“…Objective: The study aimed at ascertaining how Punch, Vanguard and Daily Trust newspapers framed oil spillage and gas flaring in Rivers State, from January 2022 to December 2023. Methods: The study adopted content analysis as its research design, thus studying 504 editions of the newspapers selected through composite week sampling. …”
Get full text

Sensitive diagnosis of paucibacillary tuberculosis with targeted next-generation sequencing: a molecular diagnostic study by Yu Chen, Lichao Fan, Zhong Ren, Yanhong Yu, Jiao Sun, Miaoran Wang, Chang Liu, Ying Zhang, Shuihua Lu, Xuhui Liu, Zhen Huang

“…Abstract Background Targeted next-generation sequencing (tNGS) enables high-performance tuberculosis (TB) diagnosis and drug resistance prediction directly from clinical samples. …”
Get full text

Analysis of micro-shear bond strength of self-etch adhesive systems with dentine: An in vitro study by Vijay Kumar Shakya, Rajeev Kumar Singh, Anjani Kumar Pathak, Balendra Pratap Singh, Anil Chandra, Ramesh Bharti, Rakesh Kumar Yadav

“…Background: Success or failure of a composite restoration largely depends on its bonding to enamel/dentine. …”
Get full text

Outcomes of Del Nido and hyperkalemic blood cardioplegia in adult cardiac surgery with prolonged aortic cross-clamp times★ by Szpytma Malgorzata, Gimpel Damian, Ross Jordan, Newland Richard F., Crouch Gareth, Rice Gregory D., Bennetts Jayme S., Baker Robert A.

“…Therefore, this study aimed to assess the safety and efficacy of our DNC strategy by comparing post-operative troponin profiles and clinical outcomes between Del Nido and hyperkalaemic cardioplegia for cases with aortic cross-clamp times of greater than 90 min. Methods: A single-centre, retrospective cohort study at Flinders Medical Centre and Flinders Private Hospital of patients undergoing composite cardiac surgery with a cross-clamp time longer than 90 min. …”
Get full text

Outcomes of Combined Left Atrial Appendage Occlusion and Transcatheter Mitral Edge-to-Edge Repair by Abdullah Al-Abcha, MD, Pietro Di Santo, MD, Charanjit S. Rihal, MD, MBA, Trevor Simard, MD, PhD, Benjamin Hibbert, MD, PhD, Mohamad Alkhouli, MD, MBA

“…Background: Up to 50% of patients undergoing mitral transcatheter edge-to-edge repair (MTEER) have an indication for left atrial appendage occlusion (LAAO). …”
Get full text

Thiazolidinedione Use and Cardiovascular Outcomes in Patients With Type 2 Diabetes Who Underwent Carotid Artery Revascularization by Jun Hwee Kim, Jimin Jeon, Seok‐Jae Heo, Tae‐Jin Song, Minyoul Baik, Joonsang Yoo, Jinkwon Kim

“…Background Thiazolidinediones are oral antidiabetic agents known for their wide‐ranging pleiotropic effects, potentially offering cardiovascular protection. …”
Get full text

Early Real-World Experience with CoreValve Evolut PRO and R Systems for Transcatheter Aortic Valve Replacement by Gaurav Rao, Shikha Sheth, Joseph Donnelly, Andrew Scatola, Umair Tariq, Saaron Laighold, Cindy Grines, Bruce Rutkin

“…The purpose of this study was to compare the efficacy and safety of the Evolut PRO to the Evolut R valve in a real-world setting. Background. The next-generation self-expanding transcatheter aortic valve replacement (TAVR) system, the CoreValve Evolut PRO was designed with an outer pericardial skirt to improve valve-sealing performance. …”
Get full text

Inflammatory changes in early dementia with Lewy bodies by Talene A. Yacoubian, Hongwei Qin, Amy Amara, Natividad Stover, Lauren Ruffrage, Yue Zhang, Richard Kennedy, David Geldmacher, Adam Gerstenecker, David G. Standaert, Etty N. Benveniste

“…ObjectiveTo examine if immune cell changes are present in early stages of Dementia with Lewy Bodies (DLB).BackgroundEvidence for inflammation in synucleinopathies has been building. …”
Get full text

Psychological needs, self-efficacy, motivation, and resistance training outcomes in a 16-week barbell training program for adults by Vanessa M. Martinez Kercher, Janette M. Watkins, Janette M. Watkins, Janelle M. Goss, Liam A. Phillips, Brad A. Roy, Kyler Blades, Dana Dobson, Kyle A. Kercher

“…BackgroundDespite extensive research on the relationship between psychological factors and aerobic training, there remains a gap in understanding these relationships within resistance training (RT), particularly barbell-based RT. …”
Get full text

Preclosure technique versus arterial cutdown after percutaneous cannulation for venoarterial extracorporeal membrane oxygenationCentral MessagePerspective by Abhimanyu Chandel, MD, Mehul Desai, MD, Liam P. Ryan, MD, Lindsay Clevenger, NP, Alan M. Speir, MD, Ramesh Singh, MD

“…Background: Arteriotomy repair through the preclosure technique during elective arterial access procedures is well documented. …”
Get full text

Mendelian randomization provides a multi-omics perspective on the regulation of genes involved in ribosome biogenesis in relation to cardiac structure and function by Shuxu Wei, Ronghuai Shen, Xiaojia Lu, Xinyi Li, Lingbin He, Youti Zhang, Jiahang Yang, Zhouwu Shu, Xianxi Huang

“…Abstract Background Ribosome biogenesis (RiboSis) is a complex process for generating ribosomes, the cellular machinery responsible for protein synthesis. …”
Get full text

Evaluation of the Efficacy of Intravenous Push and Intravenous Piggyback Ceftriaxone in Critically Ill Patients by Elly R. Sherman, Nha Hue Ta, Trisha N. Branan, Natt Patimavirujh, Luren Ashton Dickinson, Christopher M. Bland, Susan E. Smith

“…<b>Background/Objective</b>: Intravenous fluid shortages have led to fluid-sparing measures such as intravenous push (IVP) administration of antibiotics. …”
Get full text

Lipid profiles in major depression, both with and without metabolic syndrome: associations with suicidal behaviors and neuroticism by Ketsupar Jirakran, Asara Vasupanrajit, Chavit Tunvirachaisakul, Abbas F. Almulla, Marta Kubera, Michael Maes

“…Abstract Background Significant associations exist between major depressive disorder (MDD), metabolic syndrome (MetS), and cardiovascular disease, potentially attributable to heightened atherogenicity. …”
Get full text

A randomized controlled trial on the effect of hydroxychloroquine in mild Graves’ orbitopathy (GO-HCQ): study protocol by Chia-Hung Lin, Yi-Hsuan Wei, Jin-Ying Lu, Hung-Yuan Li, Chung-Wei Lee, Chung-Yi Yang, Chin-Hao Chang, Wan-Chen Wu, Chih-Yuan Wang, Shyang-Rong Shih

“…Abstract Background Graves’ orbitopathy (GO) is a prevalent manifestation of Graves’ disease (GD), characterized by proptosis, eyelid retraction, soft tissue swelling, diplopia, and potential visual acuity impairment. …”
Get full text

Liver biomarkers as predictors of prognosis in heart failure with preserved ejection fraction: a systematic review and meta-analysis by Parham Dastjerdi, Mehrdad Mahalleh, Hedieh Shayesteh, Mohammad Sadeq Najafi, Roozbeh Narimani-Javid, Mohadese Dashtkoohi, Seyed Ali Mofidi, Kaveh Hosseini, Masih Tajdini

“…Abstract Background Heart failure with preserved ejection fraction (HFpEF) accounts for 50% of heart failure cases, with increasing prevalence due to aging and risk factors such as hypertension and obesity. …”
Get full text