First genome-wide association study on anxiety-related behaviours in childhood. by Maciej Trzaskowski, Thalia C Eley, Oliver S P Davis, Sophia J Doherty, Ken B Hanscombe, Emma L Meaburn, Claire M A Haworth, Thomas Price, Robert Plomin

“…<h4>Background</h4>Twin studies have shown that anxiety in a general population sample of children involves both domain-general and trait-specific genetic effects. …”
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Ticagrelor versus Clopidogrel in Patients with Severe Renal Insufficiency Undergoing PCI for Acute Coronary Syndrome by Yunxian Chen, Shaowen Tu, Zhixin Chen, Jue Xia, Baofeng Chen, Jinfeng Chen, Jiarong Liang, Xiangyang Liu, Liangqiu Tang

“…Background. Current guidelines recommend the use of potent antiplatelet agents in patients undergoing percutaneous coronary intervention (PCI) following an acute coronary syndrome (ACS). …”
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Association between pan-immune inflammatory value and all-cause mortality in critically ill patients with ischemic stroke: a retrospective analysis of the MIMIC-IV database (2008–2... by Anni Chen, Jiahui Wang, Qiaoying Huang, Zhizhou Hu, Donglan Jiang, Yunnan Hu, Liying Pan, Jianhui Chen, Xiaohong Hu

“…This study investigates the association between the pan-immune inflammatory value (PIV)—a composite biomarker derived from routine blood tests—and all-cause mortality (ACM) in critically ill ischemic stroke patients.MethodsWe extracted data from the MIMIC-IV (v3.0) database, identifying ischemic stroke patients using ICD-9/10 codes. …”
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Associations between life’s essential 8 and arthritis among adults in United States: a national-wide longitudinal study by Feiying He, Xiangchun Xu, Hongwen Yu, Ziyang Miao, Zhaolin Fu, Lei Shi

“…Abstract Background Arthritis, a common condition in the U.S., is caused by autoimmune reactions, osteoarticular injuries, and uric acid deposition. …”
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Influence of allelic polymorphism in the 3’ untranslated region of the <i>StTCP23</i> gene on the tolerance of potato cultivars to the potato spindle tuber viroid by N. V. Mironenko, A. V. Kochetov, O. S. Afanasenko

“…Background. It is known that the pathological phenotype of potato plants can be mediated by complementary interactions between the genomic RNA of PSTVd and mRNA of some regulatory genes, which consequently lead to RNA interference, the synthesis of small interfering RNAs (vd-sRNA PSTVd), and impaired morphogenesis. …”
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Synergistic Antioxidant and Anti-Ferroptosis Therapy via BPNS-Encapsulated Thermoresponsive Chitosan Hydrogel for Spinal Cord Injury Regeneration by Yang Liu, Yingkai Wang, Xiangzi Wang, Wanchen Zeng, Zehong Zhang, Zhengmian Zhang, Zhongquan Qi

“…<b>Background</b>: Spinal cord injury (SCI) is a devastating neurological condition with limited therapeutic options. …”
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The effects of lymphocele formation after living donor kidney transplantation on mid-term allograft function by Christian Kuhn, Bernd Jänigen, Laura Matuschik, Max J. Rieger, Daniel Sidler, Stefan Zschiedrich

“…Abstract Background Despite advances in kidney transplant surgery and immunosuppression, lymphoceles remain a frequent complication in the early postoperative period following kidney transplantation, often requiring reintervention. …”
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Social and geographical inequalities in prenatal care coverage in Colombia: a multilevel analysis of individual heterogeneity and discriminatory accuracy (MAIHDA) by Juan Merlo, Sergio Prada, Merida Rodriguez-Lopez, George Leckie, Daniela Botero Jaramillo

“…Background Access to adequate antenatal care (ANC) is crucial for improving maternal and neonatal health outcomes. …”
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Cross-cultural adaptation and validation of the clinical learning evaluation questionnaire with Chinese clinical interns by Luhua Yang, Jiangang Sun, Ruirui Wang, Shaochen Tao, Shanshan Wei, Liang Dong, Yansheng Gu, Jiayue Wang

“…Abstract Background This study aimed to evaluate the reliability and validity of an adapted English questionnaire in Chinese medical schools, assessing its cross-cultural applicability in China. …”
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Unclosed wound: effect of childhood access to healthcare on cardiovascular health trajectories of Chinese older adults based on entropy balancing analysis by Boshu Mao, Xiaoyi Fang, Lingjun Liu

“…BackgroundCardiovascular Diseases (CVD) remain a leading threat among aging populations globally, with Cardiovascular Health (CVH) trajectories shaped by cumulative exposures across the life course. …”
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Robust pleiotropy-decomposed polygenic scores identify distinct contributions to elevated coronary artery disease polygenic risk. by Jiaqi Hu, Yixuan Ye, Chi Zhang, Yunfeng Ruan, Pradeep Natarajan, Hongyu Zhao

“…<h4>Background</h4>Polygenic risk score (PRS) have proved to offer robust risk prediction for coronary artery disease (CAD). …”
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The effect of different temporary filling materials and pre-endodontic build-up on fracture resistance of upper premolar teeth: an in-vitro study by Hüseyin Sinan Topçuoğlu, Salih Düzgün, İpek Eraslan Akyüz, İlke Manolya Özdemır

“…Abstract Background This study aimed to evaluate the effect of different temporary filling (TF) materials and pre-endodontic build-up on upper premolar teeth fracture resistance (FR). …”
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Oral State and Salivary Cortisol in Multiple Sclerosis Patients by Aleksandra Kapel-Reguła, Justyna Chojdak-Łukasiewicz, Anna Rybińska, Irena Duś-Ilnicka, Małgorzata Radwan-Oczko

“…<b>Background:</b> MS patients experience gradual and progressive functional limitation, bulbar symptoms, cognitive dysfunction, and psychiatric disorders that can impinge on oral status. …”
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Personalized risk assessment of drug-related harm is associated with health outcomes. by Andrea A Jones, Fidel Vila-Rodriguez, William J Panenka, Olga Leonova, Verena Strehlau, Donna J Lang, Allen E Thornton, Hubert Wong, Alasdair M Barr, Ric M Procyshyn, Geoffrey N Smith, Tari Buchanan, Mel Krajden, Michael Krausz, Julio S Montaner, G William Macewan, David J Nutt, William G Honer

“…<h4>Background</h4>The Independent Scientific Committee on Drugs (ISCD) assigned quantitative scores for harm to 20 drugs. …”
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Patient preferences for reducing bowel adverse events following prostate radiotherapy. by Mark V Mishra, Winter Maxwell Thayer, Ellen Janssen, Bradford Hoppe, Caitlin Eggleston, John F P Bridges

“…<h4>Background</h4>The Extended Prostate Cancer Index Composite (EPIC) instrument is a commonly used patient reported outcome (PRO) tool in prostate cancer clinical trials. …”
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Genotypic, Phenotypic and Clinical Validation of GeneXpert in Extra-Pulmonary and Pulmonary Tuberculosis in India. by Urvashi B Singh, Pooja Pandey, Girija Mehta, Anuj K Bhatnagar, Anant Mohan, Vinay Goyal, Vineet Ahuja, Ranjani Ramachandran, Kuldeep S Sachdeva, Jyotish C Samantaray

“…WHO recommended use of GeneXpert MTB/RIF [Xpert] for Extra-pulmonary [EP] TB; critics have since questioned its efficiency.<h4>Methods</h4>The present study was designed to assess the performance of GeneXpert in 761 extra-pulmonary and 384 pulmonary specimens from patients clinically suspected of TB and compare with Phenotypic, Genotypic and Composite reference standards [CRS].…”
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Small Tails Tell Tall Tales--Intra-Individual Variation in the Stable Isotope Values of Fish Fin. by Brian Hayden, David X Soto, Tim D Jardine, Brittany S Graham, Richard A Cunjak, Atso Romakkaniemi, Tommi Linnansaari

“…<h4>Background</h4>Fish fin is a widely used, non-lethal sample material in studies using stable isotopes to assess the ecology of fishes. …”
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The Impact of Open and Distance Learning (ODL) on Students' Psychological Well‐Being in Bangladesh: A Cross‐Sectional Study by Shahima Jabin

“…ABSTRACT Background and Aim The move towards Open and Distance Learning (ODL) has changed students' overall lives and perspectives in Bangladesh. …”
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Prognostic value of right ventricular free-wall longitudinal strain in patients with pulmonary hypertension: systematic review and meta-analyses by Tetsuji Kitano, Yosuke Nabeshima, Masaaki Takeuchi, Koichi Node

“…Background Right ventricular (RV) dysfunction is associated with adverse outcomes in patients with pulmonary hypertension (PH). …”
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Self-Expanding Versus Balloon Expanding Coronary Stents in Intervention of the Degenerated Saphenous Vein Graft: Memmingen Coronary Artery Bypass Stenosis Trial (MECAST) by Marcus Siry, Burak Duymaz, Simon Biesenberger, Deborah Siry, Vanessa Kammerer, Andreas E. May

“…The aim of this retrospective analysis was to compare the patient outcome after interventional therapy of saphenous vein graft (SVG) stenoses in an all-comers population receiving either self-expanding drug-eluting stents (SExS) or balloon expanding drug-eluting stents (BExS). Background. The interventional therapy of degenerated SVGs remains challenging. …”
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