Virulence diversity of the yellow rust pathogen population in Dagestan by E. I. Gultyaeva, E. L. Shaydayuk, R. E. Smirnova, K. M. Abdullaev, K. U. Kurkiev

“…Background. Yellow rust incidence on Triticum L. has been observed to surge up in Dagestan in recent years, facilitating selection of highly resistant genotypes. …”
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Targeting the activated microenvironment with endosialin (CD248)-directed CAR-T cells ablates perivascular cells to impair tumor growth and metastasis by Sarah L Ash, Rebecca Orha, Holly Mole, Meg Dinesh-Kumar, Steven P Lee, Frances K Turrell, Clare M Isacke

“…Background Targeting of solid cancers with chimeric antigen receptor (CAR)-T cells is limited by the lack of suitable tumor-specific antigens and the immunosuppressive, desmoplastic tumor microenvironment that impedes CAR-T cell infiltration, activity and persistence. …”
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An Observational Study of the Effect of Diet and Micronutrient Intake on the Association between Depression and Gastrointestinal Symptoms via an Online Survey Tool by Fahim Syed, Deili Sinimeri, Caroline E. Childs, Dennis Golm

“…Background and objectives: Depression is a low mood-based disorder that affects approximately one in six people in the UK. …”
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Pharmacological inhibition of tyrosine protein-kinase 2 reduces islet inflammation and delays type 1 diabetes onset in miceResearch in context by Farooq Syed, Olivia Ballew, Chih-Chun Lee, Jyoti Rana, Preethi Krishnan, Angela Castela, Staci A. Weaver, Namratha Shivani Chalasani, Sofia F. Thomaidou, Stephane Demine, Garrick Chang, Alexandra Coomans de Brachène, Maria Ines Alvelos, Eugenia Martin Vazquez, Lorella Marselli, Kara Orr, Jamie L. Felton, Jing Liu, John S. Kaddis, Piero Marchetti, Arnaud Zaldumbide, Donalyn Scheuner, Decio L. Eizirik, Carmella Evans-Molina

“…Summary: Background: Tyrosine protein-kinase 2 (TYK2) mediates inflammatory signalling through multiple cytokines, including interferon-α (IFNα), interleukin (IL)-12, and IL-23. …”
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The gut dysbiosis and plasma lipid metabolisms signatures in children with active tuberculosis by Baixu Sun, Xiaoran Yu, Hui Qi, Fang Xu, Weiwei Jiao, Min Fang, Li Duan, Xi Zeng, Xuemei Yang, Xingyun Wang, Yu Zhu, Kaixia Mi, Adong Shen, Lin Sun

“…Abstract Background The human gut microbiota is an important modulator of host immune responses and has a crucial role in the development of tuberculosis (TB). …”
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Interactions between gut microbiota, plasma metabolome and brain function in the setting of a HIV cure trial by Alessandra Borgognone, Anna Prats, Anna Prats, Ashish Arunkumar Sharma, Ignacio Martinez-Zalacaín, Ignacio Martinez-Zalacaín, Carles Soriano-Mas, Carles Soriano-Mas, Carles Soriano-Mas, Christian Brander, Christian Brander, Christian Brander, Christian Brander, Bonaventura Clotet, Bonaventura Clotet, Bonaventura Clotet, Bonaventura Clotet, Bonaventura Clotet, José Moltó, José Moltó, José Moltó, Beatriz Mothe, Beatriz Mothe, Beatriz Mothe, Beatriz Mothe, Beatriz Mothe, Rafick-Pierre Sekaly, Roger Paredes, Roger Paredes, Roger Paredes, Roger Paredes, Roger Paredes, Roger Paredes, Roger Paredes, Jose A. Muñoz-Moreno, Jose A. Muñoz-Moreno, Jose A. Muñoz-Moreno

“…BackgroundThe intestinal microbiota composition has been linked to neurocognitive impairment in people with HIV (PWH). …”
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Investigating the potential scabicidal activities of three essential oils: gaining mechanistic insights through in vitro contact bioassay and molecular docking by Rofida Wahman, Shaymaa Mohamed, Soad Bayoumi, Rana Morsy, Salma Shafie, Nada Abdelraheem, Fatma Abdelaziz, Salma Hussein, Radwa Ibrahim, Norhan Mohammed, Doaa Yones, Sara Mohammed, Alzahraa Ahmad

“…Abstract Background Scabies, sarcoptic itch, is a highly contagious and pruritic skin inflammation. …”
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Overburden failure characteristics and fracture evolution rule under repeated mining with multiple key strata control by Sun Chaoshang, Shi Chaoyang, Zhu Zhiming, Lin Haixiao, Li Zhenhua, Du Feng, Cao Zhengzheng, Lu Pengtao, Liu Lin

“…Abstract To master the overburden structure failure and fracture evolution law under multi-key stratum control during repeated mining in coal seams, this study takes the superimposed mining faces of 6# and 7# coal seams in Xinjiang mining area as the research background. Through comprehensive research methods including theoretical analysis, similarity simulation, numerical simulation, and field monitoring, it systematically reveals the evolution law of overburden fractures under repeated mining controlled by multiple key strata, and clarifies the crucial control effects of cumulative damage in the overburden and the superimposed effect of mining-induced stress fields on fracture morphology during repeated mining of close-distance coal seams. …”
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Housing Temperature Impacts the Systemic and Tissue‐Specific Molecular Responses to Cancer in Mice by Andrea Irazoki, Emma Frank, Tang Cam Phung Pham, Jessica L. Braun, Amy M. Ehrlich, Mark Haid, Fabien Riols, Camilla Hartmann Friis Hansen, Anne‐Sofie Rydal Jørgensen, Nicoline Resen Andersen, Laura Hidalgo‐Corbacho, Roberto Meneses‐Valdes, Mona Sadek Ali, Steffen Henning Raun, Johanne Louise Modvig, Samantha Gallero, Steen Larsen, Zach Gerhart‐Hines, Thomas Elbenhardt Jensen, Maria Rohm, Jonas T. Treebak, Val Andrew Fajardo, Lykke Sylow

“…ABSTRACT Background Cancer cachexia, affecting up to 80% of patients with cancer, is characterized by muscle and fat loss with functional decline. …”
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High-salt-driven gut microbiota dysfunction aggravates prostatitis by promoting AHR/SGK1/FOXO1 axis-mediated Th17 cell differentiation by Jing Chen, Rui Feng, Bin-Bin Gong, Wei-Kang Wu, Bang-Shun Dai, Rui Tan, Wen-Long Xu, Tong Meng, Xiao-Bin Wang, Yun-Zheng Xiao, Cheng Yang, Li Zhang, Chao-Zhao Liang

“…Abstract Background Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a frequently encountered disorder characterized by voiding symptoms and pelvic or perineal pain. …”
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Geochemistry and emplacement environment of intrusive bodies of Shele Boran Mo-Cu deposit (Northeast of Ahar, East Azarbaijan) by Seyed Ghafour Alavi, Mansour Kazemi rad, Mohsen Moayyed, Mohammad Reza Hosseinzadeh

“…The Oligocene intrusive bodies range, in composition, from granite, tonalite to porphyry microdiorite. …”
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Diabetic distress, low-grade chronic inflammation, and cardiac autonomic neuropathy in internally displaced people (literature review and own observations) by V.A. Serhiyenkо

“…The purpose: using the Ukrainian version of the T2-DDAS validated by us to assess the level of DD among IDP. Materials and methods. Development and application of a validated Ukrainian-language version of the Composite Autonomic Symptom Score 31 demonstrated that this is an acceptable tool for identifying patients with subclinical CAN. …”
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Exploring the concurrent validity of a linguistically responsive pre-reading assessment in bilingual children: the Urdu Phonological Tele-Assessment (U-PASS) tool by Insiya Bhalloo, Insiya Bhalloo, Monika Molnar, Monika Molnar

“…The U-PASS consists of 10 phonological awareness, phonological memory, and rapid automatized naming subtests.MethodsWe tested 115 typically-developing Urdu-English simultaneous bilinguals in Grades 1–2 across Canada and Pakistan on the U-PASS, vocabulary and reading accuracy measures, and background questionnaires.ResultsItem-level analysis, involving point-biserial correlations, accuracy rates, and Cronbach’s alpha, and linear regression, involving subtest- and composite-level analysis, were used to collect evidence for U-PASS’s internal reliability and criterion-based concurrent validity.DiscussionOur linear regression analyses indicated significant phonological processing-reading associations after accounting for background variables, thereby demonstrating U-PASS’s concurrent validity for assessing Urdu word/non-word reading. …”
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Expert consensus on the technical specifications of the in vitro skin penetration test of cosmetic product by Franz diffusion cell by Bingwen Liang, Liling Zhou, Chuanbin Wu, Liang Fang, Lisheng Wang, Lihua Peng, Peng Shu, Lifeng Tang, Yu Bei, Xiaodong Cui, Xiaojia Chen, Yuan Gao, Chong Han, Yan Jia, Huaqing Lin, Yifang Li, Ying Liu, Yiguang Li, Zhiwei Li, Zixiu Liu, Shaohua Ren, Jun Shi, Wanyang Sun, Lijuan Tian, Qun Wang, Yuan Wang, Yuehong Xu, Ming Zeng, Quangang Zhu, Shu Zhang, Yifan Zhang, Qi Xiang

“…Background: Diffusion cell test is one of the most commonly used in vitro model to detect the percutaneous absorption of cosmetic ingredients. …”
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Falls prevention interventions for community-dwelling older adults: systematic review and meta-analysis of benefits, harms, and patient values and preferences by Jennifer Pillay, Lindsay A. Gaudet, Sabrina Saba, Ben Vandermeer, Ashiqur Rahman Ashiq, Aireen Wingert, Lisa Hartling

“…Abstract Background About 20–30% of older adults (≥ 65 years old) experience one or more falls each year, and falls are associated with substantial burden to the health care system, individuals, and families from resulting injuries, fractures, and reduced functioning and quality of life. …”
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Evaluation of parenting interventions for those with additional health and social care needs during pregnancy: THRIVE a multi-arm RCT with embedded economic and process components by Marion Henderson, Anja Wittkowski, Katie Buston, Karen Crawford, Alice MacLachlan, Alex McConnachie, Emma McIntosh, Claudia-Martina Messow, Catherine Nixon, Rosaleen O’Brien, Shona Shinwell, Daniel Wight, Yiqiao Xin, Rachel Calam, Ruth Dundas, James Law, Helen Minnis, Lucy Thompson, Philip Wilson

“…Background Women who have additional social and care needs in pregnancy (e.g. social adversity, maternal depression and anxiety) are likely to produce high levels of stress hormones. …”
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Impact of family socio-economic status on the prognosis of heart transplantation in children by Shun Liu, Han Mo, Yiqi Zhao, Xiao Chen, Weiteng Wang, Yijing Li, Ningning Zhang, Mengni Bao, Zeyu Cui, Qian Zhao, Jun Yan, Xiumeng Hua, Jiangping Song

“…Abstract Background Low family socio-economic status is a known factor that can contribute to increased mortality for patients with cardiovascular disease. …”
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Associations of Adipokine Levels With Levels of Remnant Cholesterol: The Multi‐Ethnic Study of Atherosclerosis by Renato Quispe, Ty Sweeney, Seth S. Martin, Steven R. Jones, Matthew A. Allison, Matthew J. Budoff, Chiadi E. Ndumele, Mohamed B. Elshazly, Erin D. Michos

“…Understanding the association between adipokines, endogenous hormones produced by adipose tissue, and remnant cholesterol (RC) would give insight into the link between obesity and atherosclerotic cardiovascular disease. Methods and Results We studied 1791 MESA (Multi‐Ethnic Study of Atherosclerosis) participants who took part in an ancillary study on body composition with adipokine levels measured (leptin, adiponectin, and resistin) at either visit 2 or visit 3. …”
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Cardiovascular Health Effects and Synthetic Cooling Agents in E‐Cigarettes Labeled as “Clear” Marketed in Massachusetts After the Tobacco Product Flavoring Ban by Erika T. Minetti, Hanno C. Erythropel, Rachel Keith, Danielle R. Davis, Julie B. Zimmerman, Suchitra Krishnan‐Sarin, Naomi M. Hamburg

“…We studied their acute hemodynamic impact and chemical composition. Methods In participants (age 18–45 years) in the Cardiovascular Injury due to Tobacco Products 2.0 study (Boston, MA), we measured changes in blood pressure and heart rate following a structured use of participants' own e‐cigarettes. …”
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Infant Gut Microbiota and Childhood Blood Pressure: Prospective Associations and the Modifying Role of Breastfeeding by Tiange Liu, Jakob Stokholm, Mingyu Zhang, Rebecca Vinding, Søren J. Sørensen, Ni Zhao, Noel T. Mueller

“…Background Germ‐free mice experiments indicate that human gut microbiota influence blood pressure (BP), but no studies have prospectively examined if infant gut microbiota affects their future childhood BP. …”
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