Characterizing Nonculprit Lesions and Perivascular Adipose Tissue of Patients Following Acute Myocardial Infarction Using Coronary Computed Tomography Angiography: A Comparative St... by Xiaomeng Wang, Ching H. Sia, Philip D. Adamson, Charlotte E. Greer, Weimin Huang, Hwee K. Lee, Shuang Leng, Yan T. Loong, Nur A. S. Raffiee, Swee Y. Tan, Sock H. Tan, Lynette L. S. Teo, Sung L. Wong, Xiaoxun Yang, Min S. Yew, Thon H. Yong, Liang Zhong, Leslee J. Shaw, Mark Y. Y. Chan, Derek J. Hausenloy, Lohendran Baskaran

“…Background The comparison of coronary computed tomography angiography plaques and perivascular adipose tissue (PVAT) between patients with acute myocardial infarction (AMI) posttreatment and patients with stable coronary artery disease is poorly understood. …”
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Traditional ecological knowledge for great ape conservation in Gabon by Mohamed H. Mohamed-Djawad, Neil M. Longo-Pendy, Serge Ely Dibakou, Costanza Puppo, Jean Nzue-Nguema, Désiré Otsaghe-Ekore, Patrice Makouloutou-Nzassi, Cyr Moussadji-Kinga, Alain P. Kouga, Barthelemy Ngoubangoye, Pape Ibnou Ndiaye, Larson Boundenga

“…Abstract Background Traditional ecological knowledge (TEK) held by Indigenous communities is increasingly recognised as a cost effective, locally adapted complement to instrument-based wildlife monitoring. …”
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Phytochemical Profiling and Biological Evaluation of <i>Dianthus sylvestris</i> subsp. <i>aristidis</i>: A Chromatographic and Mass Spectrometry Approach to Uncovering Bioactive Me... by Amina Bouzana, Zohra Chekroud, Imène Becheker, Fatima Kamah, Nora Sakhraoui, Chawki Bensouici, Fehmi Boufahja, Sulaiman A. Alsalamah, Mohammed I. Alghonaim, Stefania Garzoli, Hamdi Bendif

“…<b>Background/Objectives</b>: This study provides the first comprehensive phytochemical composition and biological evaluation of <i>Dianthus sylvestris</i> subsp. …”
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Trajectory correction enables free-running chemical shift encoded imaging for accurate cardiac proton-density fat fraction quantification at 3T by Pierre Daudé, Thomas Troalen, Adèle L.C. Mackowiak, Emilien Royer, Davide Piccini, Jérôme Yerly, Josef Pfeuffer, Frank Kober, Sylviane Confort Gouny, Monique Bernard, Matthias Stuber, Jessica A.M. Bastiaansen, Stanislas Rapacchi

“…ABSTRACT: Background: Metabolic diseases can negatively alter epicardial fat accumulation and composition, which can be probed using quantitative cardiac chemical shift encoded (CSE) cardiovascular magnetic resonance (CMR) by mapping proton-density fat fraction (PDFF). …”
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A novel interplay between bacteria and metabolites in different early-stage lung cancer: an integrated microbiome and metabolome analysis by Xiaoqian Zhai, Xiaoqian Zhai, Dongqi Lin, Dongqi Lin, Yi Shen, Yi Shen, Ni Zhai, Fan Yu, Fan Yu, Jiabi Zhang, Yiyun Lin, Yuqing Wang, Qinghua Zhou, Qinghua Zhou, Xi Zheng, Xi Zheng

“…BackgroundThe carcinogenesis mechanism of early-stage lung cancer (ESLC) remains unclear. …”
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Exploring the mechanisms of tetrahydrocurcumin in ameliorating nonalcoholic steatohepatitis based on network pharmacology and gut microbiota analysis in vivo and in vitro by Keyu Chen, Keyu Chen, Keyu Chen, Jianbo Wang, Jianbo Wang, Shuang Luo, Yunyun Quan, Ping Wei, Jiali Fu, Jiali Ma, Yuying Yang, Yunten Liu, Zhichong Gao, Zhichong Gao, Zhichong Gao

“…BackgroundThe prevalence of nonalcoholic steatohepatitis (NASH) is increasing every year, and there are very few approved therapeutic agents globally, making the search for potentially targeted therapeutic agents important.AimsTo investigate the anti-NASH effect of tetrahydrocurcumin (THC) and to further study the biological mechanism of THC anti-NASH from the perspective of intestinal flora.MethodsSeven-week-old female male C57BL/6J mice were randomly divided into two batches of six groups: (1) control group, (2) model group, (3) positive control group, (4) THC low-dose group, (5) THC medium-dose group, and (6) THC high-dose group. …”
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Examining the social distributions in neighbourhood black carbon and ultrafine particles in Montreal and Toronto, Canada by Emmanuelle Batisse, Marshall Lloyd, Alicia Cavanaugh, Arman Ganji, Junshi Xu, Marianne Hatzopoulou, Jill Baumgartner, Scott Weichenthal

“…Methods: We collected vulnerability indicators, including social, economic, household composition, and immigration status, at the dissemination area level for Montreal and Toronto using data from the 2006 and 2021 Canadian Census of Population. …”
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Conjugated bile acids promote metabolic dysfunction-associated steatotic liver disease through inducing nuclear translocation of sphingosine-1-phosphate receptor 2 to disrupt perox... by Rong-Rong Miao, Ming-Yong Tan, Han-Bing Shao, Zhi-Meng Sun, Sheng Zhan, Wei-Shi Liang, Xiao-Hui Liu, Ke-Qin Li, Yu-Yao Cheng, Xin-Feng Wu, Rui Xu, Shu-Xiang Cui, Yong Hai, Xian-Jun Qu

“…Abstract Background Conjugated bile acids (CBAs) induced metabolic dysfunction-associated steatotic liver disease (MASLD) through activating sphingosine-1-phosphate receptor 2 (S1PR2). …”
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Comparative Analysis of Gut Microbiota Diversity Across Different Digestive Tract Sites in Ningxiang Pigs by Wangchang Li, Xianglin Zeng, Lu Wang, Lanmei Yin, Qiye Wang, Huansheng Yang

“…However, the diversity and functional roles of microbiota in different nutrient absorption tissues remain underexplored. Methods: We collected samples from four key nutrient absorption tissues (NFC: Cecal Content, NFI: Ileal Content, NFL: Colonic Content, NFG: Gastric Content, N = 6) of Ningxiang pigs and performed 16S rRNA gene sequencing to analyze microbial community composition. …”
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Study on the improvement of cognitive deficits in APP/PS1 mice by danggui shaoyao san and its disassembled prescriptions through modulation of the gut microbiota by Xingduo Liu, Chaoqun Sun, Yuqiong Dai, Feifei Duan, Tianzhen He, Menglu Zhen, Enxi Liang, Shuting Zhang, Yun Xia, Nianchun Hu, Ruoting Zhan, Ruoting Zhan, Dong Deng, Sijun Liu

“…BackgroundAlzheimer’s disease (AD), a neurodegenerative disorders linked to gut microbiota dysbiosis, may benefit from Traditional Chinese Medicine (TCM) interventions.ObjectivesDanggui Shaoyao San (DSS), a classic traditional Chinese Medicine (TCM) formula. …”
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Combination of Sodium Butyrate and Immunotherapy in Glioma: regulation of immunologically hot and cold tumors via gut microbiota and metabolites by Sui Li, Sui Li, Li Wang, MingYu Han, Huali Fan, Hailin Tang, Huile Gao, Guobo Li, Zheng Xu, Zhaokai Zhou, JunRong Du, Cheng Peng, Fu Peng, Fu Peng

“…BackgroundRecent studies have highlighted the importance of cross-talk along the gut-brain axis in regulating inflammatory nociception, inflammatory responses, and immune homeostasis. …”
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Regional and aging-specific cellular architecture of non-human primate brains by Yun-Mei Wang, Wen-Chao Wang, Yongzhang Pan, Lin Zeng, Jing Wu, Zheng-Bo Wang, Xiao-Lin Zhuang, Ming-Li Li, David N. Cooper, Sheng Wang, Yong Shao, Li-Min Wang, Ying-Yin Fan, Yonghan He, Xin-Tian Hu, Dong-Dong Wu

“…Abstract Background Deciphering the functionality and dynamics of brain networks across different regions and age groups in non-human primates (NHPs) is crucial for understanding the evolution of human cognition as well as the processes underlying brain pathogenesis. …”
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Muscle‐specific gene editing improves molecular and phenotypic defects in a mouse model of myotonic dystrophy type 1 by Mariapaola Izzo, Jonathan Battistini, Elisabetta Golini, Christine Voellenkle, Claudia Provenzano, Tiziana Orsini, Georgios Strimpakos, Ferdinando Scavizzi, Marcello Raspa, Denisa Baci, Svetlana Frolova, Spyros Tastsoglou, Germana Zaccagnini, Jose Manuel Garcia‐Manteiga, Genevieve Gourdon, Silvia Mandillo, Beatrice Cardinali, Fabio Martelli, Germana Falcone

“…Abstract Background Myotonic dystrophy type 1 (DM1) is a genetic multisystemic disease, characterised by pleiotropic symptoms that exhibit notable variability in severity, nature and age of onset. …”
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Sudden death due to enterotoxemia amongst Arabian camels (Camelus dromedaries) and associated risk factors by Asmaa G. Mubarak, Fatma A. Khalifa, Yumna Elsobky, Ahmed Abdel-Rady, Wael Felefel, Adel Hassan Saad, Ehab Y. Abdelhiee, Abdullah Mohamed Alhassan, Hisham Awny, Eman M. Elghazaly, Ashraf M. Abu-Seida, Abdulrahman Abdulkarim, Asmaa G. Youseef

“…Background: Sudden death is defined as an unexpected death occurring with no observed antecedent clinical signs. …”
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Treatment of hypothyroidism with levothyroxine plus slow-release liothyronine: a study protocol for a randomized controlled double-blinded clinical trial by F. Azizi, A. Amouzegar, H. Abdi, M. Tohidi, S. Masoumi, D. Khalili, Y. Mehrabi, A. Zadehvakili, M. Hedayati, A. A. Momenan, L. Mehran

“…Abstract Background There are emerging controversies regarding the priority of T4 + T3 combination therapy over standard care with levothyroxine (LT4) monotherapy in the management of hypothyroid subjects. …”
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Genome editing of TXNIP in human pluripotent stem cells for the generation of hepatocyte-like cells and insulin-producing islet-like aggregates by Leonardo Traini, Javier Negueruela, Bernat Elvira, Wadsen St-Pierre-Wijckmans, Valerie Vandenbempt, Carlos E. Buss, Ao Li, Israel Pérez-Chávez, Francisco Ribeiro-Costa, Mariana Nunes, Joris Messens, Daria Ezeriņa, David C. Hay, Mayank Bansal, Esteban N. Gurzov

“…Abstract Background Thioredoxin-interacting protein (TXNIP) plays a role in regulating endoplasmic reticulum (ER) and oxidative stress, which disrupt glucose homeostasis in diabetes. …”
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Evaluating the relationship between circulating lipoprotein lipids and apolipoproteins with risk of coronary heart disease: A multivariable Mendelian randomisation analysis. by Tom G Richardson, Eleanor Sanderson, Tom M Palmer, Mika Ala-Korpela, Brian A Ference, George Davey Smith, Michael V Holmes

“…<h4>Background</h4>Circulating lipoprotein lipids cause coronary heart disease (CHD). …”
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In Vitro Evaluation of Rosemary Essential Oil: GC-MS Profiling, Antibacterial Synergy, and Biofilm Inhibition by Daniel E. K. Kabotso, David Neglo, Sarah E. Gaba, Emmanuel K. Danyo, Alberta D. Dayie, Anastasia A. Asantewaa, Fleischer C. N. Kotey, Nicholas T. K. D. Dayie

“…<b>Background:</b> Antimicrobial resistance (AMR) has become precarious, warranting investments in antimicrobial discovery. …”
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Dietary exposure to nitrites and nitrates in association with type 2 diabetes risk: Results from the NutriNet-Santé population-based cohort study. by Bernard Srour, Eloi Chazelas, Nathalie Druesne-Pecollo, Younes Esseddik, Fabien Szabo de Edelenyi, Cédric Agaësse, Alexandre De Sa, Rebecca Lutchia, Charlotte Debras, Laury Sellem, Inge Huybrechts, Chantal Julia, Emmanuelle Kesse-Guyot, Benjamin Allès, Pilar Galan, Serge Hercberg, Fabrice Pierre, Mélanie Deschasaux-Tanguy, Mathilde Touvier

“…<h4>Background</h4>Nitrites and nitrates occur naturally in water and soil and are commonly ingested from drinking water and dietary sources. …”
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Taxed and untaxed beverage intake by South African young adults after a national sugar-sweetened beverage tax: A before-and-after study. by Michael Essman, Lindsey Smith Taillie, Tamryn Frank, Shu Wen Ng, Barry M Popkin, Elizabeth C Swart

“…<h4>Background</h4>In an effort to prevent and reduce the prevalence rate of people with obesity and diabetes, South Africa implemented a sugar-content-based tax called the Health Promotion Levy in April 2018, one of the first sugar-sweetened beverage (SSB) taxes to be based on each gram of sugar (beyond 4 g/100 ml). …”
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