Potential effects of Asian-adapted Mediterranean diet in depression and anxiety among women with metabolic dysfunction-associated steatotic liver disease: a secondary analysis by Alicia Salamanca-Sanabria, Yu Chung Chooi, Evelyn Xiu Ling Loo, Evelyn Xiu Ling Loo, Xianning Lai, Vera Sergeyevna Brok Volchanskaya, Yap Seng Chong, Yap Seng Chong, Johan Gunnar Eriksson, Johan Gunnar Eriksson, Johan Gunnar Eriksson, Johan Gunnar Eriksson, Johan Gunnar Eriksson

“…We previously reported that a calorie-restricted MD adapted to the Asian food culture has beneficial effects on body composition, liver fat, and cardiometabolic markers in Chinese Singaporean women with MASLD.ObjectiveThis secondary analysis examines the effects of an Asian-adapted MD on the symptoms of anxiety and depression in the same population.MethodsIn a double-blind, parallel-design, randomized controlled trial, 84 Chinese- Singaporean females with MASLD were randomly assigned to 1 of the 3 groups for 12 weeks: adapted Asian MD with C15:0 supplementation (n = 29), diet without C15:0 supplementation (n = 26), or control (habitual diet and no C15:0 supplementation, n = 29). …”
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A platform for multisite immune profiling of premetastatic pancreatic cancer at single-cell resolution by Elishama N. Kanu, Ashley A. Fletcher, Jiayin Bao, Ethan S. Agritelley, Julia Button, Austin M. Eckhoff, Karrie Comatas, Tao Wang, Bin-Jin Hwang, Michael E. Lidsky, Sabino Zani, Dan G. Blazer, Peter J. Allen, Zhicheng Ji, Frank J. Lowery, Sri Krishna, Nicholas D. Klemen, Daniel P. Nussbaum, Erika J. Crosby

“…Abstract Background Pancreatic ductal adenocarcinoma (PDAC) is characterized by exceedingly high rates of metastatic progression, with the liver representing the most common site of distant spread. …”
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Association between birth length, linear growth velocities, and primary school achievement at age 10 years: evidence from the Ethiopian iABC birth cohort by Rahma Ali, Beakal Zinab, Bikila S. Megersa, Daniel Yilma, Tsinuel Girma, Alemseged Abdissa, Melkamu Berhane, Bitiya Admasu, Suzanne Filteau, Dorothea Nitsch, Henrik Friis, Jonathan C. K. Wells, Gregers S. Andersen, Mubarek Abera, Mette F. Olsen, Rasmus Wibaek, Akanksha A. Marphatia

“…We assessed associations between birth length, childhood linear growth velocities, and stunting with school achievement. Methods Newborns were recruited into the Ethiopian infant Anthropometry and Body Composition (iABC) birth cohort and followed from birth to 10 years. …”
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Endurance running during late murine adolescence results in a stronger anterior cruciate ligament and flatter posterior tibial slopes compared to controls by Danielle N. Ochocki, Benjamin E. Loflin, Taeyong Ahn, Kaitlyn A. Colglazier, Andrew R. Young, Anna A. Snider, Elizabeth P. Bueckers, Edward M. Wojtys, Stephen H. Schlecht

“…Abstract Background Anterior cruciate ligament (ACL) injury rates continue to rise among youth involved in recreational and competitive athletics, requiring a better understanding of how the knee structurally and mechanically responds to activity during musculoskeletal growth. …”
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ITIH4 alleviates OVA-induced asthma by regulating lung-gut microbiota by Yi-Hsuan Liu, Yueh-Lun Lee, Chia-Li Han, Yu-Chun Lo, Zih-An Liao, Yu-Syuan Shih, Yi-Wen Lin, Syue-Wei Peng, Kang-Yun Lee, Shu-Chuan Ho, Sheng-Ming Wu, Cheng-Wei Lin, Kian Fan Chung, Jer-Hwa Chang, Hsiao-Chi Chuang

“…Abstract Background Inter-alpha-trypsin inhibitor heavy chain 4 (ITIH4), a Type 2 acute phase protein, is critical for resolving inflammation and promoting tissue repair. …”
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Varied cellular abnormalities in thin vs. normal endometrium in recurrent implantation failure by single-cell transcriptomics by Xiaoying Fu, Xiaoyan Guo, Han Xu, Yini Li, Bihui Jin, Xirong Zhang, Chongyi Shu, Yuhang Fan, Yiqi Yu, Yuqing Tian, Jiao Tian, Jing Shu

“…Abstract Background Reduced endometrium thickness and receptivity are two important reasons for recurrent implantation failure (RIF). …”
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Investigation of Bioactive Compounds Extracted from <i>Verbena officinalis</i> and Their Biological Effects in the Extraction by Four Butanol/Ethanol Solvent Combinations by Dejan Stojković, Nikoleta Đorđevski, Mladen Rajaković, Biljana Filipović, Jelena Božunović, Stefani Bolevich, Gokhan Zengin, Sergey Bolevich, Uroš Gašić, Marina Soković

“…<b>Background/Objectives</b>: <i>Verbena officinalis</i> L. …”
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Safety, Immunogenicity and Protective Activity of a Modified Trivalent Live Attenuated Influenza Vaccine for Combined Protection Against Seasonal Influenza and COVID-19 in Golden S... by Ekaterina Stepanova, Victoria Matyushenko, Daria Mezhenskaya, Ekaterina Bazhenova, Tatiana Kotomina, Alexandra Rak, Svetlana Donina, Anna Chistiakova, Arina Kostromitina, Vlada Novitskaya, Polina Prokopenko, Kristina Rodionova, Konstantin Sivak, Kirill Kryshen, Valery Makarov, Larisa Rudenko, Irina Isakova-Sivak

“…Background/Objectives: Influenza viruses and SARS-CoV-2 are currently cocirculating with similar seasonality, and both pathogens are characterized by a high mutational rate which results in reduced vaccine effectiveness and thus requires regular updating of vaccine compositions. …”
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Efficacy and mechanism of long-snake moxibustion for treating insomnia in breast cancer survivors: study protocol for a randomized controlled trial by Cuicui Gong, Huakang Li, Qiang Li, Pengxuan Gu, Qi Xiao, Yunjing Jia, Qian Xiao, Yuanzhen Mi, Shanshan Wei, Ziliang Wu, Bing Lin, Zhonglin Zhang

“…BackgroundInsomnia (difficulty falling or staying asleep) is a common issue among breast cancer survivors, significantly impacting their quality of life. …”
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Does time matter? Intraspecific diversity of ribosomal RNA genes in lineages of the allopolyploid model grass Brachypodium hybridum with different evolutionary ages by Dana Trunova, Natalia Borowska-Zuchowska, Serhii Mykhailyk, Kai Xia, Yuanbin Zhu, Ruben Sancho, Magdalena Rojek-Jelonek, Sònia Garcia, Kai Wang, Pilar Catalan, Ales Kovarik, Robert Hasterok, Bozena Kolano

“…Abstract Background Polyploidisation often results in genome rearrangements that may involve changes in both the single-copy sequences and the repetitive genome fraction. …”
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Monocyte-derived APCs are central to the response of PD1 checkpoint blockade and provide a therapeutic target for combination therapy by Louis Boon, Matheus H W Crommentuijn, Sjoerd T T Schetters, Laura J W Kruijssen, Yvette van Kooyk, Ernesto Rodriguez, Jan Van den Bossche, Joke M M Den Haan

“…Background PD1 immune checkpoint blockade (αPD1 ICB) has shown unparalleled success in treating many types of cancer. …”
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Predicting acute lung injury in infants with congenital heart disease after cardiopulmonary bypass by gut microbiota by Lan Jiang, Yueshuang Cun, Qiang Wang, Kede Wu, Menglong Hu, Zhen Wu, Tianyi Zhu, Zhaocong Yang, Nishant Patel, Nishant Patel, Xinyu Cai, Xinyu Cai, Jirong Qi, Xuming Mo

“…BackgroundAcute lung injury (ALI) is a serious and common complication that occurs in children with congenital heart disease after cardiopulmonary bypass (CPB) surgery, leading to higher mortality rates and poorer prognosis. …”
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Microwave-dried black soldier fly larvae enhance growth, intestinal health, and humoral imm by Osfar Sjofjan, Ari Ardiantoro, Inaayah Novitri Cahyawati, Amalia Iffah Jihana, Muhammad Halim Natsir, Yuli Frita Nuningtyas, Danung Nur Adli

“…Background and Aim: The global demand for sustainable animal protein sources has led to the exploration of insects as alternative feed ingredients. …”
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Efficacy and safety of dietary polyphenol supplements for COPD: a systematic review and meta-analysis by Dongsheng Wu, Dongsheng Wu, Yuang Dong, Dongyang Zhang, Tongtong Wang, Haipeng Ye, Wei Zhang

“…BackgroundThe therapeutic application of dietary polyphenols in chronic obstructive pulmonary disease (COPD) management represents an emerging therapeutic paradigm in pulmonary medicine. …”
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Multi-region brain transcriptomic analysis of amyotrophic lateral sclerosis reveals widespread RNA alterations and substantial cerebellum involvement by Natalie Grima, Andrew N. Smith, Claire E. Shepherd, Lyndal Henden, Thiri Zaw, Luke Carroll, Dominic B. Rowe, Matthew C. Kiernan, Ian P. Blair, Kelly L. Williams

“…Abstract Background Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that primarily affects the motor neurons, causing progressive muscle weakness and paralysis. …”
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Bioactive compound combinations from Rhodiola tangutica alleviate pulmonary vascular remodeling in high-altitude pulmonary hypertension rats through the PI3K–AKT pathway by Na Yang, Meiduo Huayu, Shanshan Su, Bin Hou, Zhanting Yang, Xingmei Nan, Zhanqiang Li, Zhanqiang Li

“…Although its active fraction (ACRT) shows therapeutic potential for HAPH, the main pharmacodynamic substances remain unclear due to its complex composition.AimsThis study aimed to identify bioactive equivalent combinatorial components (BECCs) of ACRT that alleviate pulmonary vascular remodeling in HAPH rats and explore the underlying pharmacological mechanisms.MethodsSeventy adult Sprague–Dawley rats were divided into control, hypoxia, hypoxia + ACRT (150 mg/kg), hypoxia + BECCs (25, 50, and 100 mg/kg), and hypoxia + sildenafil (30 mg/kg) groups. …”
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DENTAL STATUS OF PRESCHOOL CHILDREN WITH MOUTH BREATHING by L.P. Ulasevych

“…The purpose of our study was to assess the dental status of preschool children with oral breathing to develop more effective methods of preventing caries of temporary teeth that can be applied chairside during the dental appointment. …”
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Cancer incidence in young adults aged 20 to 44 years old in the Siberian Federal District by L. D. Zhuikova, E. L. Choynzonov, A. D. Kaprin, A. O. Shakhzadova, O. A. Ananina, G. A. Kononova, L. V. Pikalova, M. Yu. Grishchenko, E. V. Denisov

“…The purpose of the study was to assess the incidence of the most common cancers in young men and women aged 20 to 44 years in the SFD. Material and Methods. The study used data from the state medical statistics reports (form 7, “Information on malignant neoplasms”) of the SFD subjects, as well as data on the age and sex composition of the population of these territories for 2014–2023. …”
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Late bedtime was associated with increased androgen and reduced lean mass in women with polycystic ovary syndrome: a cross-sectional study by Yuqin Zhang, Min Zhang, Meili Cai, Xiaowen Shao, Diliqingna Dilimulati, Jiayi Lu, Cuiling Zhu, Haibing Chen, Changbin Li, Shen Qu, Manna Zhang

“…Abstract Background While the specific effects of bedtime on androgen levels and lean muscle mass remain understudied, circadian misalignment and sleep disturbances have been well-established as risk factors for various metabolic disorders. …”
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Haptoglobin and Glutamine Synthetase May Biomark Cachexia Induced by Antiacute Myeloid Leukaemia Chemotherapy by Dean G. Campelj, Cara A. Timpani, Guinevere Spiesberger, Luke E. Formosa, Joel R. Steele, Haijian Zhang, Ralf B. Schittenhelm, Lewis Leow, Craig A. Goodman, Emma Rybalka

“…ABSTRACT Background Anticancer chemotherapy is an underappreciated contributor to cancer cachexia, an often‐irreversible body‐wasting condition that causes 20%–30% of cancer‐related deaths. …”
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