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3161
Hepatocyte-derived liver progenitor-like cells attenuate liver cirrhosis via induction of apoptosis in hepatic stellate cells
Published 2025-02-01“…Background:. Cell therapy demonstrates promising potential as a substitute therapeutic approach for liver cirrhosis. …”
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3162
Multi-omics insights implicate the remodeling of the intestinal structure and microbiome in aging
Published 2024-11-01“…However, the mechanisms underlying the development of inflammaging remain unknown.MethodsWe conducted 16S rRNA sequencing of intestinal contents from young and old C57BL/6J mice to elucidate changes in gut microbiota diversity and microbial community composition after aging. …”
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3163
Process Development for GMP-Grade Full Extract Cannabis Oil: Towards Standardized Medicinal Use
Published 2025-06-01“…<b>Background/Objectives:</b> The industrial extraction and purification processes of <i>Cannabis sativa</i> L. compounds are critical steps in creating formulations with reliable and reproducible therapeutic and sensorial attributes. …”
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3164
Multi-omics characterization of diabetic nephropathy in the db/db mouse model of type 2 diabetes
Published 2025-01-01“…Methods: Renal tissues from db/db mice underwent integrative multi-omics analysis, encompassing transcriptomics, metabolomics, and lipidomics. …”
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3165
Dietary Qiwenghuangbo powder–enriched Limosilactobacillus reuteri protects the intestinal epithelium and alleviates inflammation via a strain‐specific mechanism
Published 2025-06-01“…Abstract Background Qiwenghuangbo powder (QP), composed of Astragalus, Phellodendron chinensis, and Radix pulsatilla, is a traditional Chinese herbal formula, but its effects on weaned piglets remained unclear. …”
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3166
Exploring the health benefits of outdoor exercise for cancer survivors: a systematic review of more than 700 individuals
Published 2025-05-01“…Abstract Background Cancer’s rising incidence and growing survivor population underscore the need for strategies to enhance health and quality of life. …”
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3167
RETRACTED: Identification of novel candidate targets for suppressing ovarian cancer progression through IL-33/ST2 axis components using the system biology approach
Published 2023-06-01“…Background: Cancer-associated fibroblasts (CAFs) of ovarian cancer (OvC) are the most prevalent element of the tumor microenvironment (TM). …”
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3168
The effects of a combined recovery strategy during a match-congested period crossing Ramadan: a repeated measurements crossover study among professional male basketball players
Published 2025-03-01“…Background: A good recovery process is a key factor to avoid fatigue and sports-related injuries in Muslim male basketball players, especially during some decisive phases of the sport season, such as the match congestion period coinciding with Ramadan intermittent fasting (RIF). …”
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3169
The alternations of gut microbiota in diabetic kidney disease: insights from a triple comparative cohort
Published 2025-06-01“…BackgroundDiabetic kidney disease (DKD) exhibits heterogeneous progression, implicating factors beyond hyperglycemia, such as gut microbiota dysbiosis. …”
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3170
Improving the Synthesis of Odd-Chain Fatty Acids in the Oleaginous Yeast <i>Yarrowia lipolytica</i>
Published 2024-11-01“…(1) Background: Odd-chain fatty acids (OCFAs) have garnered attention for their potential health benefits and unique roles in various biochemical pathways. …”
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3171
A Novel Metabolic Risk Classification System Incorporating Body Fat, Waist Circumference, and Muscle Strength
Published 2025-02-01“…It aims to improve risk stratification and evaluate the association with metabolic syndrome. <b>Methods</b>: This cross-sectional study involved 300 young adults (18–22 years) from a university in Mexico City, utilizing body composition (%BF) and anthropometric measures (WC, GS) to categorize them into four risk groups: protective, low risk, increased risk, and high risk. …”
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3172
Fluctuating saline conditions favor competition of Bolboschoenus planiculmis, a dominant species in inland salt marshes
Published 2025-08-01“…Abstract Background The changing hydrological conditions in wetland ecosystems are often accompanied by salt fluctuations. …”
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3173
Metabolic and Structural Consequences of GM3 Synthase Deficiency: Insights from an HEK293-T Knockout Model
Published 2025-04-01“…<b>Background</b>: GM3 Synthase Deficiency (GM3SD) is a rare autosomal recessive neurodevelopmental disease characterized by recurrent seizures and neurological deficits. …”
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3174
Circulating Microvesicles Enriched in miR–126–5p and miR–223–3p: Potential Biomarkers in Acute Coronary Syndrome
Published 2025-02-01“…<b>Methods.</b> Bioinformatic tools identified miRNAs linked to ACS. …”
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3175
Effects of antibiotic therapy on the early development of gut microbiota and butyrate-producers in early infants
Published 2025-01-01“…BackgroundAntibiotics, as the most commonly prescribed class of drugs in neonatal intensive care units, have an important impact on the developing neonatal gut microbiota. …”
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3176
Deubiquitinating Enzymes Regulate Skeletal Muscle Mitochondrial Quality Control and Insulin Sensitivity in Patients With Type 2 Diabetes
Published 2025-04-01“…ABSTRACT Background Activation of mitochondrial fission and quality control occur early in the onset of insulin resistance in human skeletal muscle. …”
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3177
Novel potential biomarkers for predicting childhood caries via metagenomic analysis
Published 2025-06-01“…BackgroundDental caries is a prevalent global health issue, particularly among children, with significant oral and overall health implications. …”
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3178
Effect of mixed protein supplementation on golf performance and muscle function: a randomized, double-blind, placebo-controlled study
Published 2024-12-01“…Background As a relatively novel approach to enhancing skeletal muscle health, mixed protein supplementation has shown similar responses to whey protein. …”
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3179
Single-nucleus RNA sequencing reveals the specific molecular signatures of myeloid cells responding to brain injury after microglial replacement
Published 2025-07-01“…BackgroundMyeloid cells, such as resident microglia (MG), infiltrating monocytes (Mo), macrophages (MΦ), and CNS border-associated macrophages (BAM) in the brain, participate in aged brain injury. …”
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3180
Effects of a multicomponent exercise regimen on subchondral bone and cartilage in postmenopausal women with knee osteoarthritis: protocol for a randomized controlled trial
Published 2025-06-01“…Abstract Background Knee osteoarthritis (KOA) is considered a whole-joint disease that is amenable to prevention and treatment in the early stages. …”
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