Comprehensive quality profiling and multivariate analysis of rice (Oryza sativa L.) cultivars: integrating physical, cooking, nutritional, and micronutrient characteristics for enh... by Khaled M. H. Abdelsalam, Ahmed M. Shaalan, Germine M. AbouEl-Soud, Medhat A. E. El-Dalil, Abdelsalam M. Marei, Diaa Abd El-Moneim, Aly A. A. El-Banna, Sobhi F. Lamlom, Ahmed M. Abdelghany

“…Abstract Background Rice (Oryza sativa L.) is a staple food for nearly half the global population, with rice grain quality (RGQ) and yield being the most valuable attributes for consumers and food security. …”
Get full text

The Epidemic Process of Measles with Different Strategies of Vaccination in a Large Industrial Center of the Middle Urals by A. A. Golubkova, T. A. Platonova, S. S. Smirnova, S. A. Kovyazina

“…However, against this background, 2016 was registered a major outbreak of measles.Conclusion. …”
Get full text

Polymorphisms in the inflammatory pathway genes TLR2, TLR4, TLR9, LY96, NFKBIA, NFKB1, TNFA, TNFRSF1A, IL6R, IL10, IL23R, PTPN22, and PPARG are associated with susceptibility of in... by Steffen Bank, Paal Skytt Andersen, Johan Burisch, Natalia Pedersen, Stine Roug, Julie Galsgaard, Stine Ydegaard Turino, Jacob Broder Brodersen, Shaista Rashid, Britt Kaiser Rasmussen, Sara Avlund, Thomas Bastholm Olesen, Hans Jürgen Hoffmann, Marianne Kragh Thomsen, Vibeke Ostergaard Thomsen, Morten Frydenberg, Bjørn Andersen Nexø, Jacob Sode, Ulla Vogel, Vibeke Andersen, Vibeke Andersen

“…<h4>Background</h4>The inflammatory bowel diseases (IBD), Crohn's disease (CD) and ulcerative colitis (UC), result from the combined effects of susceptibility genes and environmental factors. …”
Get full text

Stomatobaculum longum-Derived Extracellular Vesicles Enhance Oral Squamous Cell Carcinoma Malignancy Through BRCA1/EXO1/TP53BP1 Modulation by Yan L, Wu F, Jiao J, Maimaiti A, Li Y, Shao L, Liang Q, Xiong X, Qin Z

“…This study investigates the role of the oral microbiome, particularly Stomatobaculum longum (S. longum), in OSCC progression and explores the underlying molecular mechanisms involving bacterial extracellular vesicles (EVs).Methods: 16S rRNA sequencing was conducted on tumor and adjacent non-tumor tissues from OSCC patients to identify microbial composition. …”
Get full text

Protective Effects of Frankincense Oil on Wound Healing: Downregulating Caspase-3 Expression to Facilitate the Transition from the Inflammatory to Proliferative Phase by Krishnaraju Venkatesan, Durgaramani Sivadasan, Moufida Abderrahmen Al Weslati, Mohammed Gayasuddin Mouid, Manoj Goyal, Monika Bansal, Mohamed EL-Dosoky Mohamed Salama, Syed Azizullah Ghori, Fazil Ahmad

“…This study investigates the protective effects of FEO in an excision wound model in rats, focusing on oxidative stress reduction, inflammatory cytokine modulation, and caspase-3 regulation. <b>Methods:</b> The chemical composition of FEO was analyzed using gas chromatography-mass spectrometry (GC-MS). …”
Get full text

Sex-Dependent Effects of Body Fat on Cardiac Function and Outcomes in Community-Dwelling Older Adults by Haowen Jiang, MBBS, Jie Jun Wong, MBBS, Glades H.M. Tan, BEng, Louis L.Y. Teo, MBBS, See Hooi Ewe, MBBS, PhD, Ru-San Tan, MBBS, Fei Gao, PhD, Angela S. Koh, MBBS, MPH, PhD

“…Background: Among older adults, sex hormones may exert differential effects on body fat and cardiac health. …”
Get full text

Gut microbiota in women with polycystic ovary syndrome: an individual based analysis of publicly available dataResearch in context by Yanan Yang, Jiale Cheng, Chongyuan Liu, Xiaopo Zhang, Ning Ma, Zhi Zhou, Weiying Lu, Chongming Wu

“…Summary: Background: Polycystic ovary syndrome (PCOS) represents a prevalent endocrine disorder affecting numerous females worldwide. …”
Get full text

Skeletal Muscle‐Specific Deletion of E3 Ligase Asb2 Enhances Muscle Mass and Strength by Hye Rim Jang, Shi‐Young Park, Yeonmi Lee, Dongjin Lee, Jongjun Lee, Yoonil Cho, Cheol Soo Choi, Hui‐Young Lee

“…ABSTRACT Background Maintaining skeletal muscle mass and strength is crucial to prevent sarcopenia during healthy ageing. …”
Get full text

Prevalence and Associated Factors of Sarcopenic Obesity Among Nursing Home Residents: A Cross‐Sectional Multi‐Centre Study by Doris Eglseer, Hristo Hristov, Sanja Krušič, Nadan Gregorič, Irena Hren, Igor Pravst, Živa Lavriša

“…ABSTRACT Background Obesity and sarcopenia are prevalent among older adults and associated with adverse health outcomes. …”
Get full text

Correction of regulatory molecules expression at the inflammation stage using photobiomodulation therapy in chronic wound modeling by М.V. Kumechko, N.М. Babenko, S.B. Pavlov, О.B. Litvinova, І.І. Torianyk, О.І. Babaieva

“…Background. The search for effective treatments for chronic wounds continues. …”
Get full text

Taurine alleviated paraquat-induced oxidative stress and gut-liver axis damage in weaned piglets by regulating the Nrf2/Keap1 and TLR4/NF-κB signaling pathways by Chen Chen, Min Qi, Weilong Zhang, Fanxing Chen, Zhihong Sun, Weizhong Sun, Wenjie Tang, Zhenguo Yang, Xuan Zhao, Zhiru Tang

“…Abstract Background Oxidative stress can impair intestinal barrier function and cause liver damage, resulting in reduced animal productivity. …”
Get full text

Limosilactobacillus reuteri prevents progression of ankylosing spondylitis in mice by restoring gut microbiota-metabolism homeostasis by Lianjun Yang, Ke You, Kun Wang, Bin Liu, Tao Chen, Zhifei Cui, Dawei Zhang, Zhihai Su, Xiang Liu, Hai Lu

“…Abstract Background Ankylosing spondylitis (AS) is a chronic inflammatory disease characterized by progressive spinal fusion and systemic inflammation. …”
Get full text

Rehabilitation after bone marrow transplant compared with usual care to improve patient outcomes (REBOOT): protocol for a randomised controlled trial by Linda Denehy, Shaza Abo, Christopher Swain, Camille E. Short, Nicole Kiss, Amit Khot, Eric Wong, Duncan Purtill, Clare O’Donnell, Marlena Klaic, Catherine L. Granger, Michelle Tew, Tim Spelman, Vinicius Cavalheri, Lara Edbrooke, on behalf on the REBOOT research team

“…Abstract Background Haematological cancer affects more than 1.3 million people around the world annually and accounted for almost 800,000 deaths globally in 2020. …”
Get full text

The role of polygenic susceptibility to obesity among carriers of pathogenic mutations in MC4R in the UK Biobank population. by Nathalie Chami, Michael Preuss, Ryan W Walker, Arden Moscati, Ruth J F Loos

“…<h4>Background</h4>Melanocortin 4 receptor (MC4R) deficiency, caused by mutations in MC4R, is the most common cause of monogenic forms of obesity. …”
Get full text

Effect of screw pressing temperature on yield, bioactive compounds, and quality of hemp (Cannabis sativa L.) seed oil by Aymane Allay, Abdessamad Ben Moumen, Youssef Rbah, Marie-Laure Fauconnier, Jacques Nkengurutse, Hana Serghini Caid, Ahmed Elamrani, Farid Mansouri

“…This study aims to assess the effects of different screw press extraction temperatures on hemp oil yield, composition and quality. Methods The study was conducted to examine the influence of screw press extraction temperatures (30, 60, 80, 100, 120 and 140 °C) on hemp oil yield and quality. …”
Get full text

A1 protein free milk benefits mood and subjective cognition in free-living Australian adults: a pragmatic, exploratory, open label randomised controlled trial by Carlene Starck, Michelle Blumfield, Peter Petocz, Emily Duve, Lucy Downey, Kylie Abbott, Flavia Fayet-Moore, Flavia Fayet-Moore

“…BackgroundAdverse effects of milk containing A1-type β-casein on digestion, immune response, and cognition have been identified in milk-intolerant individuals, but health effects in healthy individuals without symptoms of milk intolerance are yet to be examined.ObjectiveThe objective was to explore the impact of reducing A1 type β-casein intake via switching milk type from conventional A1/A2-type β-casein milk (A1/A2 milk) to A1-type β-casein protein free milk (A1PF) on brain, immune response, gastrointestinal, and skin (BIGS) outcomes in a real-world setting.MethodsAn open-label, pragmatic, exploratory randomised controlled trial was conducted in 997 healthy, free-living Australian older adolescents and adults (16–65 years) who regularly consume A1/A2 protein-containing milk and milk products. …”
Get full text

A comprehensive analysis of the tryptophan metabolism-related gene signature to predict the prognosis of esophageal squamous cell carcinoma based on multi-omics by Zhengjie Wu, Zhiping Liu, Yukun Wang, Geling Teng, Xiaodong Li, Tong Lu, Fangning Hu, Shuo Wu, Guanqiang Ma, Hua Zhang

“…BackgroundTryptophan (Trp) metabolism plays a vital role in tumor development and outcomes. …”
Get full text

Intranasal Transplantation of Microbiota Derived from Parkinson’s Disease Mice Induced Astrocyte Activation and Neurodegenerative Pathology from Nose to Brain by Yi-Meng Xia, Mei-Xuan Zhang, Xiao-Yu Ma, Lu-Lu Tan, Ting Li, Jian Wu, Ming-An Li, Wei-Jiang Zhao, Chen-Meng Qiao, Xue-Bing Jia, Yan-Qin Shen, Chun Cui

“…Background: Parkinson’s disease (PD) is characterized by early-onset olfactory dysfunction preceding motor symptoms, yet its mechanisms remain elusive. …”
Get full text

Exploring the impact of chronic intermittent EU-GMP certified Cannabis sativa L. therapy and its relevance in a rat model of aging by Ivona-Maria Tudorancea, Gabriela-Dumitrita Stanciu, Carmen Solcan, Mitica Ciorpac, Andrei Szilagyi, Daniela-Carmen Ababei, Raluca-Maria Gogu, Bogdan-Ionel Tamba

“…Abstract Background Aging is a multifaceted process marked by the progressive accumulation of cellular damage in various tissues, resulting in a decline in physiological functions. …”
Get full text

Success Factors of Growth-Stage Digital Health Companies: Systematic Literature Review by Estelle Pfitzer, Laura Bitomsky, Marcia Nißen, Christoph Kausch, Tobias Kowatsch

“… BackgroundOver the past decade, digital health technologies (DHTs) have grown rapidly, driven by innovations such as electronic health records and accelerated by the COVID-19 pandemic. …”
Get full text