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2941
Alpine Adaptive Mechanism on Rhizosphere Microbes Recruitment of <i>Crepis napifera</i> (Franch.) Babc. by Multi-Omics Analysis
Published 2025-03-01“…Babc., a regionally significant medicinal plant, contains a diverse array of terpenoids and demonstrates substantial potential for resource development and utilization. <b>Methods:</b> Transcriptome sequencing, metabolomic profiling, and 16S rRNA gene amplicon sequencing were employed to assess the transcriptional expression patterns, metabolic variations, and rhizosphere microbial community composition of <i>C. napifera</i> (Franch.) …”
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2942
The effect of eight weeks of progressive resistance training with garlic supplementation on serum levels of C-reactive protein and insulin resistance in overweight women
Published 2022-06-01“…Background and Purpose: Resistance exercise can reduce inflammation. …”
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2943
Postbiotic-Based Extracts from Native Probiotic Strains: A Promising Strategy for Food Preservation and Antimicrobial Defense
Published 2025-03-01“…<b>Background/Objectives</b>: The deterioration of food quality and safety is often linked to the presence of pathogenic and spoilage microorganisms. …”
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2944
Machine learning-assisted analysis of serum metabolomics and network pharmacology reveals the effective compound from herbal formula against alcoholic liver injury
Published 2025-04-01“…Nevertheless, the effective compound is challenging to identify due to its intricate composition and multiple targets. Methods An integration machine learning-assisted approach was established, whereby the particular action mechanism and direct target were obtained through the correlation of compounds, targets, and metabolites. …”
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2945
Total and regional fat-to-muscle mass ratio and risks of pan-cancer: a prospective cohort study
Published 2025-05-01“…Abstract Background The fat-to-muscle mass ratio (FMR) has served as a marker for various diseases. …”
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2946
Development of the 10-question household foodwork interactional assessment questionnaire (FIA-Q10)
Published 2024-11-01“…Abstract Background Public health nutrition recommendations and clinical dietary interventions emphasize eating healthy food at home, implicitly requiring household foodwork. …”
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2947
The Beneficial Application of Turmeric (Curcuma longa L.) on Health and Egg Production, in Layers: A Review
Published 2024-11-01“…ABSTRACT Background Turmeric (Curcuma longa L.) is a widely recognized spice and medicinal plant that has gained significant attention for its potential health benefits. …”
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2948
Gut-Microbiome Signatures Predicting Response to Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer: A Systematic Review
Published 2025-06-01“…Background and Objectives: Rectal cancer management increasingly relies on watch-and-wait strategies after neoadjuvant chemoradiotherapy (nCRT). …”
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2949
Research on the correlation between gut microbiota and brain cognitive function under chronic hypoxia at high altitude
Published 2025-06-01“…BackgroundLong-term exposure to high-altitude hypoxia can lead to cognitive impairment, yet the role of the gut microbiota in this process remains unclear. …”
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2950
Evaluating Medical Entity Recognition in Health Care: Entity Model Quantitative Study
Published 2024-10-01“… BackgroundNamed entity recognition (NER) models are essential for extracting structured information from unstructured medical texts by identifying entities such as diseases, treatments, and conditions, enhancing clinical decision-making and research. …”
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2951
Randomized Clinical Evaluation of the Healing Activity of Green Propolis Ointment in Individuals with Lower Limb Ulcers Resulting from Leprosy: Preliminary Results of a Pilot Study
Published 2024-12-01“…<b>Background/Objectives:</b> Treating chronic wounds incurs substantial costs for Brazil’s Unified Health System. …”
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2952
Determination of pKA of nonvolatile weak acids in plasma of healthy volunteers and critically ill patients
Published 2025-06-01“…Abstract Background The dissociation constant of nonvolatile weak acids in plasma (KA), expressed as pKA, is essential for electroneutrality-based acid–base analysis. …”
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2953
Tertiary lymphoid structures correlate with the therapeutic efficacy and prognosis of resectable esophageal squamous cell carcinoma undergoing neoadjuvant chemoradiotherapy plus im...
Published 2025-08-01“…BackgroundTertiary lymphoid structures (TLSs) are linked to prognosis in esophageal squamous cell carcinoma (ESCC), but whether the distribution, abundance, and maturity of TLSs affect therapeutic efficacy and prognosis in ESCC treated with neoadjuvant chemoradiotherapy plus immunotherapy (NRCI) remains unclear. …”
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2954
Exploring the bacterial communities in date palm roots in saline versus non-saline environment
Published 2025-07-01“…Abstract Background Bacterial communities associated with plant roots significantly influence plant growth and adaptation to environmental stresses, particularly in arid agroecosystems. …”
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2955
Osteogenic and Antibacterial Response of Levofloxacin-Loaded Mesoporous Nanoparticles Functionalized with <i>N</i>-Acetylcysteine
Published 2025-04-01“…These nanoparticles would present antibacterial activity able to disintegrate the biofilm and regenerate the peri-implantar osseous tissue. <b>Methods</b>: MBGN of composition 82.5 SiO<sub>2</sub>—17.5 CaO have been synthesized, loaded with levofloxacin, and functionalized with NAC (MBGN-L-NAC). …”
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2956
Global burden of gallbladder and biliary diseases (1990–2021) with healthcare workforce analysis and projections to 2035
Published 2025-04-01“…Abstract Background Gallbladder and biliary tract diseases pose a significant global health burden, yet comprehensive analyses of their long-term epidemiological trends and future projections remain limited. …”
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2957
Evaluation of the Cytotoxicity, Genotoxicity and Acute Oral Toxicity of <i>Thymus longicaulis</i> subsp. <i>chaubardii</i> (Rchb.f.) Jalas
Published 2025-07-01“…The aim of this study was to determine its phytochemical profile and to evaluate its cytotoxic, genotoxic and acute oral toxicity effects. <b>Methods</b>: The phenolic composition of the methanolic extract was determined by HPLC-DAD. …”
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2958
Gut microbiota dysbiosis in patients with Alzheimer’s disease and correlation with multiple cognitive domains
Published 2024-11-01“…The aim of this study was to explore microbial signatures associated with global cognition and specific cognitive domains in AD patients and to determine their predictive value as biomarkers.MethodsA total of 64 subjects (18 mild AD, 23 severe AD and 23 healthy control) were recruited in the study. 16 s rDNA sequencing was performed for the gut bacteria composition, followed by liquid chromatography electrospray ionization tandem mass spectrometry (LC/MS/MS) analysis of short-chain fatty acids (SCFAs). …”
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2959
Association analysis-based screening strategy for quality markers of Tengdan capsule in the treatment of hypertensive renal disease
Published 2025-08-01“…This study aimed to identify candidate Q-markers of TDC and elucidate the molecular pathways through which it exerts its renoprotective effects, using an integrative association analysis-based approach.MethodsThe chemical composition of TDC and its potential Q-markers were systematically characterized through in vitro and in vivo profiling using HPLC-Q-Exactive-MS and chromatographic fingerprinting. …”
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2960
Circ_HUWE1: a novel regulator of lipid accumulation, inflammation, and gut microbiota in atherosclerosis
Published 2025-07-01“…Abstract Background Atherosclerosis (AS) is a chronic cardiovascular disease characterized by lipid accumulation and inflammation within arterial walls, leading to plaque formation and cardiovascular events. …”
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