A BOX-YOLOv8 framework for automated hyperspectral core analysis by Hongyan Zhu, Anjie Li, Chengzhi Lin, Shuai Qin, Junhao Xie, Jackey J.K. Chai, Russell Rogers, Jun-Li Xu

“…The framework identifies core boxes (BOX-YOLOv8, achieving 99.5% mAP@0.5), precisely segments these boxes for geometric correction (SAM2), and segments core/soil material from the background using spectral differences (MLP). This automated pipeline significantly improves processing time compared to manual methods. …”
Get full text

Brain age mediates gut microbiome dysbiosis-related cognition in older adults by Sang Joon Son, Dong Yun Lee, Hyun Woong Roh, Maria Ly, Antonija Kolobaric, Howard Aizenstein, Carmen Andreescu, Eldin Jašarević, Tharick A. Pascoal, Pamela C. L Ferreira, Bruna Bellaver, Yong Hyuk Cho, Sunhwa Hong, You Jin Nam, Bumhee Park, Narae Kim, Jin Wook Choi, Jae Youn Cheong, Yoon-Keun Kim, Tae-Seop Shin, Chil-Sung Kang, Cheol-O Kwon, Seo-Yoon Yoon, Chang Hyung Hong, Helmet T. Karim

“…Abstract Background Recent studies have focused on improving our understanding of gut microbiome dysbiosis and its impact on cognitive function. …”
Get full text

Machine learning integrates region-specific microbial signatures to distinguish geographically adjacent populations within a province by Li Luo, Li Luo, Bangwei Chen, Bangwei Chen, Shengyin Zeng, Shengyin Zeng, Yaxin Li, Yaxin Li, Xiaolin Chen, Xiaolin Chen, Jianguo Zhang, Xiangjie Guo, Shujin Li, Lei Ruan, Shida Zhu, Cairong Gao, Cuntai Zhang, Tao Li

“…BackgroundThe individual specificity and temporal stability of the human gut microbiota have revealed significant compositional differences across geographical provenances. …”
Get full text

Altered heme metabolism and hemoglobin concentration due to empirical antibiotics-induced gut dysbiosis in preterm infants by Seung Hyun Kim, Min‑Jin Kwak, Jae Kyoon Hwang, Jihyun Keum, Hee Yeon Jin, Chan-Yeong Lee, Rahul Sadashiv Tanpure, Yong Joo Kim, Jeong-Kyu Hoh, Jae Yong Park, Woojin Chung, Byong-Hun Jeon, Hyun-Kyung Park

“…Background: High-risk infants are usually treated with empirical antibiotics after birth, regardless of the evidence of infection; however, their gut microbiome and metabolome have seldom been studied. …”
Get full text

Microenvironment-related predictive markers of the therapeutic effectiveness of eribulin in patients with locally advanced or metastatic breast cancer: pilot study by L.  A. Tashireva, N. O. Popova, V. V. Alifanov, V. E.  Goldberg, E. I. Kovalenko, E. V. Artamonova, A. G.  Manikhas, D. M. Ponomarenko, N. V. Levchenko, E. I. Rossokha, S. Yu.  Krasilnikova, M. A. Zafirova, V. M.  Perelmuter

“…Background. Triple negative breast cancer has no specific treatment sites for chemotherapy and is unfavorable in terms of prognosis. …”
Get full text

Natural Honey-Propolis Combinations with Health-Promoting Potential: Antibacterial Activity Against Foodborne Pathogens by Vanesa Sánchez-Martín, Marta B. López-Parra, Amaia Iriondo-DeHond, Aneta Wojdyło, Anna Michalska-Ciechanowska, Ana I. Haza, Paloma Morales, María Dolores del Castillo

“…<b>Background/Objectives:</b> Natural products such as honey and propolis have been widely studied for their antimicrobial properties. …”
Get full text

Bifidobacterium longum subsp. infantis CCFM1426 enhances the anti-colitic effect of vitamin A via retinoic acid restoration and gut microbiota modulation in ulcerative colitis mice by Xihua Yu, Xihua Yu, Liming Huang, Liming Huang, Yi Wang, Yi Wang, Liuruolan Li, Liuruolan Li, Wenwei Lu, Wenwei Lu, Zhijian Zhang, Hongchao Wang, Hongchao Wang

“…BackgroundUlcerative colitis (UC) is a chronic inflammatory bowel disease with increasing global prevalence, making it a significant health concern. …”
Get full text

Association between gut microbiota and ultra-processed foods consumption among the patients with type 2 diabetes: a cross-sectional study by Takahiro Ichikawa, Yoshitaka Hashimoto, Yusuke Igarashi, Sayaka Kawai, Ayumi Kaji, Ryosuke Sakai, Takafumi Osaka, Ryo Inoue, Saori Kashiwagi, Katsura Mizushima, Kazuhiko Uchiyama, Tomohisa Takagi, Yuji Naito, Masahide Hamaguchi, Michiaki Fukui

“…Methods This cross-sectional study included 362 participants with T2D. …”
Get full text

Association between reduced lung function, hydration and nutritional status in patients on hemodialysis: An observational study using bioelectrical impedance vector analysis (BIVA) by Sheila Borges, Angela Teodósio da Silva, Taís Ferreira Martins, Letícia de Araújo Morais, Felipe Vilaça Cavallari Machado, Gerson Cipriano Júnior, Graziella França Bernardelli Cipriano

“…Methods: A cross-sectional study, including patients with CKD on HD, age >18 years. …”
Get full text

Rethinking the Paradigm of Using Ps for Diagnosing Compartment Syndrome by Yasser Bouklouch, BSc, MPH, July Agel, MA, ATC, William T. Obremskey, MD, MPH, MMHC, Andrew H. Schmidt, MD, Kathy Liu, MB, ChB, Jerald R. Westberg, MPH, Matthew Zakariah, BSc, Eli Bunzel, MD, Greer Henry, MSc, Andres Fidel Diaz, MD, Thierry Bégué, MD, Mitchell Bernstein, MD, Edward J. Harvey, MDCM, MSc

“…Methods:. Retrospective data of 357 patients were obtained from the databases of 5-level one trauma centers in Canada, the United States, and France. …”
Get full text

Development of the breastfed infant oral microbiome over the first two years of life in the BLOSOM Cohort by Roaa A. Arishi, Roaa A. Arishi, Roaa A. Arishi, Roaa A. Arishi, Ali S. Cheema, Ching T. Lai, Ching T. Lai, Ching T. Lai, Matthew S. Payne, Donna T. Geddes, Donna T. Geddes, Donna T. Geddes, Lisa F. Stinson, Lisa F. Stinson, Lisa F. Stinson

“…BackgroundAcquisition and development of the oral microbiome are dynamic processes that occur over early life. …”
Get full text

A Ketogenic Diet Followed by Gradual Carbohydrate Reintroduction Restores Menstrual Cycles in Women with Polycystic Ovary Syndrome with Oligomenorrhea Independent of Body Weight Lo... by Rebecca Rossetti, Vittoria Strinati, Alessandra Caputi, Renata Risi, Maria Letizia Spizzichini, Alessandro Mondo, Lorenzo Spiniello, Carla Lubrano, Antonella Giancotti, Dario Tuccinardi, Lucio Gnessi, Mikiko Watanabe

“…<b>Background/Objectives</b>: Polycystic ovary syndrome (PCOS) is a common endocrine disorder in women of fertile age. …”
Get full text

Single-cell transcriptomics reveal the prognostic roles of epithelial and T cells and DNA methylation-based prognostic models in pancreatic cancer by Jing Du, Yaqian Zhao, Jie Dong, Peng Li, Yan Hu, Hailang Fan, Feifan Zhang, Lanlan Sun, Dake Zhang, Yuhua Zhang

“…Abstract Background Pancreatic adenocarcinoma (PDAC) exhibits a complex microenvironment with diverse cell populations influencing patient prognosis. …”
Get full text

Spatial transcriptomic analysis of tumor microenvironment in esophageal squamous cell carcinoma with HIV infection by Yuanli Zuo, Yang Jin, Gang Li, Yue Ming, Ting Fan, Yitong Pan, Xiaojun Yao, Yong Peng

“…Abstract Background Human Immunodeficiency Virus (HIV) is one of the most prevalent viruses, causing significant immune depletion in affected individuals. …”
Get full text

Antimicrobial Effectiveness of <i>Ribes nigrum</i> L. Leaf Extracts Prepared in Natural Deep Eutectic Solvents (NaDESs) by Maria-Beatrice Solcan, Ana-Maria Vlase, Gabriel Marc, Dana Muntean, Tibor Casian, George Cosmin Nadăș, Cristiana Ștefania Novac, Daniela-Saveta Popa, Laurian Vlase

“…Methods: Two hydrogen-bond acceptors (HBAs) and three hydrogen-bond donors (HBDs) were tested. …”
Get full text

Recovery of Perennial Plant Communities in Disturbed Hyper-Arid Environments (Sharaan Nature Reserve, Saudi Arabia) by Sami Youssef, Mohamed Djamel Miara, Stéphane Boivin, Robin Sallio, Jérôme Nespoulous, Hassan Boukcim, Sami D. Almalki, Shauna K. Rees, Benjamin P. Y.-H. Lee, Ahmed H. Mohamed

“…Background: Human activities such as agriculture are known to markedly affect natural ecosystems, including plant communities and soil properties. …”
Get full text

Distinct germ-line genetic mutation patterns correlate with reproductive outcomes in ICSI patients: a pilot study by Ting Jiang, Yan Wang, Wandai Wu, Qianru Yang, Sixian Wu, Xueguang Zhang, Wenming Xu

“…While conventional genetic testing using blood samples is common in reproductive medicine, the genetic composition of sperm may differ significantly from somatic cells due to mosaicism and de novo mutations during spermatogenesis.MethodsWe collected semen samples from 11 couples with varying ICSI outcomes: successful clinical pregnancy (n = 6), implantation failure (n = 3), and early pregnancy loss (n = 2). …”
Get full text

Mind the blind spot: lessons from fungal community sequencing in a plant–soil feedback experiment by Mengshuai Liu, Jose G. Maciá-Vicente, Jasper van Ruijven, Wopke van der Werf, Zhenling Cui, Fusuo Zhang, Chunxu Song, Liesje Mommer

“…Abstract Background Plant–soil feedback (PSF) has gained increasing interest in agricultural systems. …”
Get full text

Preliminary Evaluation of 3D-Printed Alginate/Gelatin Scaffolds for Protein Fast Release as Suitable Devices for Personalized Medicine by Benedetta Ghezzi, Ruben Foresti, Luisa Pia Scialoia, Maddalena Botti, Arianna Mersanne, Fulvio Ratto, Francesca Rossi, Chiara Martini, Paolo Perini, Elda Favari, Antonio Freyrie

“…<b>Background/Objectives:</b> Drug-coated balloons (DCBs) are emerging as a promising treatment for peripheral artery disease; however, current technologies lack flexibility in customizing drug release profiles and composition, limiting their therapeutic potential. …”
Get full text

Energy metabolism and whole-exome sequencing-based analysis of Sasang constitution: a pilot study by Hyoung Kyu Kim, Heetak Lee, Ji Ho So, Seung Hun Jeong, Dae Yun Seo, Jong-Yeol Kim, Sanguk Kim, Jin Han

“…Background: Traditional Korean Sasang constitutional (SC) medicine categorizes individuals into four constitutional types [Tae-eum (TE), So-eum (SE), Tae-yang (TY), or So-yang (SY)] based on biological and physiological characteristics. …”
Get full text