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2741
High oxidative phosphorylation represented by UQCRFS1 marks CD8 + tumor-infiltrating lymphocytes exhaustion in diffuse large B-cell lymphoma
Published 2025-08-01“…Abstract Background Metabolic alterations are closely associated with the exhaustion and immune deficiency of CD8+ tumor-infiltrating lymphocytes (TILs), while little is known about diffuse large B-cell lymphoma (DLBCL). …”
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2742
Effect of treadmill walking on cardiometabolic risk factors and liver function markers in older adults with MASLD: a randomized controlled trial
Published 2025-04-01“…Abstract Background Regular walking has been reported to improve metabolically-associated steatotic liver disease (MASLD) by altering the metabolic environment. …”
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2743
Changes in rat liver fatty acid profile in experimental non-alcoholic steatohepatitis
Published 2021-12-01“…The demonstrated shifts in FA composition may reflect both adaptive and pathological changes in the liver of animals with NAFLD and require further study.…”
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2744
From Cell Lines to Patients: Dissecting the Proteomic Landscape of Exosomes in Breast Cancer
Published 2025-04-01“…<b>Background:</b> Breast cancer (BC) is the most common cancer among women worldwide; therefore, the efforts of many scientists are aimed at finding effective biomarkers for this disease. …”
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2745
Gut microbiota dysbiosis and associated immune response in systemic lupus erythematosus: impact of disease and treatment
Published 2025-02-01“…Abstract Background Gut microbial dysbiosis and leaky gut play a role in systemic lupus erythematosus (SLE). …”
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2746
Effect of meal time on postprandial glycemia in patients with type 2 diabetes mellitus and obesity not receiving insulin
Published 2023-11-01“…BACKGROUND: Postprandial hyperglycemia (PPG) is associated with micro- and macrovascular diseases in patients with T2DM. …”
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2747
Effect of a ketogenic diet, time-restricted eating, or alternate-day fasting on weight loss in adults with obesity: a randomized clinical trial
Published 2025-07-01“…Abstract Background Studies evaluating the effects of novel, alternative dietary approaches for weight loss compared with the Mediterranean diet (MedDiet) are lacking. …”
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2748
Unveiling the Antioxidant Power and Secondary Metabolites of <i>Tabebuia chrysantha</i> (Jacq.) Leaves and Flowers from Ecuador
Published 2025-04-01“…<b>Background</b>: <i>Tabebuia chrysantha</i> (Jacq.) Nichols, commonly known as Guayacan, is a prominent species within the Bignoniaceae family known for its medicinal value and ecological significance. …”
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2749
Chemical Characteristics of Stack Particulate Matter Emitted from Sintering Process of an Integrated Steel Mill and Resolution of Source Contributors on Boundary PM2.5
Published 2025-05-01“…Abstract Background This study investigated the chemical characteristics of PM2.5 emitted from the sintering process of an integrated steel mill and assesses the contribution of emission sources to boundary PM2.5. …”
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2750
Changes of Microbiome in Human Papillomavirus Infection and Cervical Cancer: A Systematic Review and Meta‐Analysis
Published 2025-06-01“…ABSTRACT Background and Objectives We aimed to conduct a systematic review and meta‐analysis of high‐throughput sequencing studies to assess changes in microbiome alpha, beta diversity, and composition differences in patients with human papillomavirus (HPV) infection and cervical cancer. …”
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2751
Preschoolers in severely food insecure Guatemalan Mayan households consume a monotonous grain-based diet
Published 2025-08-01“…Abstract Background Stunting, also known as growth retardation, is a prominent health challenge for Mayan children, stemming from the complex interaction of malnutrition, inflammation, limited healthcare access, poverty, and food insecurity. …”
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2752
Mixture Containing 5% Polysaccharide Extract of <i>Cerioporus squamosus</i> (Huds.) Quélet, 5% Dexpanthenol, and 0.2% Hyaluronic Acid Shows In Vitro and In Vivo Wound Healing Prope...
Published 2025-03-01“…<b>Background:</b> This study explores wound healing and the antimicrobial potential of a natural formulation containing a polysaccharide extract from <i>Cerioporus squamosus</i>, hyaluronic acid, and dexpanthenol. …”
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2753
Effects of different fiber levels of energy feeds on rumen fermentation and the microbial community structure of grazing sheep
Published 2025-03-01“…Abstract Background Rumen microbial community structure and stability are very important for ruminant health, growth and development, and livestock product yield. …”
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2754
Whole genome comparisons reveal gut-to-lung translocation of Escherichia coli and Burkholderia cenocepacia in two cases of ventilator-associated pneumonia in ICU patients
Published 2025-05-01“…Abstract Background Identifying the sources of pathogenic bacteria causing ventilator-associated pneumonia (VAP) in intensive care unit (ICU) patients is crucial for developing effective prevention and treatment strategies. …”
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2755
Sterile syringe availability in Georgia pharmacies remained rare, despite policy change permitting sales
Published 2025-08-01“…Abstract Background Numerous states, including Georgia in April 2019, have advanced policies designed to increase availability of sterile syringes in pharmacies for people who inject drugs (PWID); however, the extent to which pharmacies are willing to sell syringes to PWID is unclear. …”
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2756
Single-cell RNA-sequencing uncovers the dynamic changes of tumour immune microenvironment in advanced lung adenocarcinoma
Published 2023-07-01“…Background The heterogeneity of lung adenocarcinoma (LUAD) plays a vital role in determining the development of cancer and therapeutic sensitivity and significantly hinders the clinical treatment of LUAD.Objective To elucidate the cellular composition and reveal previously uncharacterised tumour microenvironment in LUAD using single-cell RNA-sequencing (scRNA-seq).Methods Two scRNA-seq datasets with 106 829 high-quality cells from 34 patients including 11 normal, 9 early (stage I and II) and 14 advanced (stage III and IV) LUAD were integrated and clustered to explore diagnostic and therapeutic cell populations and their biomarkers for diverse stages of LUAD. …”
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2757
Diversity, distribution, and conservation status of Macrobrachium shrimp in freshwater ecosystems of Aceh, Indonesia
Published 2025-08-01“…Background and Aim: Freshwater shrimps of the genus Macrobrachium play key ecological and socioeconomic roles in tropical freshwater ecosystems. …”
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2758
Analgesic effect of Dahuang Fuzi Decoction in neuropathic pain through inhibiting TNF-α and PI3K-AKT signaling
Published 2024-12-01“…However, the mechanisms through which DF exerts its effects remain largely unknown.MethodsIn this study, we employed ultra-high-performance liquid chromatography coupled with high-resolution mass spectrometry (UHPLC-HRMS) to analyze the chemical composition of DF. …”
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2759
Anxiety-related gut microbiota alterations in Parkinson’s disease: distinct associations compared to healthy individuals
Published 2025-06-01“…Background and objectivesAnxiety affects 25–49% of Parkinson’s disease (PD) patients, exacerbating non-motor symptoms and significantly reducing quality of life. …”
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2760
Can muscle synergies shed light on the mechanisms underlying motor gains in response to robot-assisted gait training in children with cerebral palsy?
Published 2025-02-01“…Abstract Background Children with cerebral palsy (CP) often experience gait impairments. …”
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