Body shape index (ABSI), body roundness index (BRI) and risk factors of metabolic syndrome among overweight and obese adults: a cross-sectional study by MohammadSalar Fahami, Ali Hojati, Mahdieh Abbasalizad Farhangi

“…Abstract Background Metabolic syndrome (MetS) is one of the most significant public health issues worldwide, which increases the risk of various diseases. …”
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Metabarcoding with Illumina and Oxford Nanopore Technologies provides complementary insights into tree seed mycobiota by Jana Mittelstrass, Renate Heinzelmann, René Eschen, Martin Hartmann, Quirin Kupper, Salome Schneider, Simone Prospero, Iva Franić

“…Abstract Background Culturing of fungi is labor-intensive and reveals limited diversity, while high-throughput sequencing of barcodes (i.e., metabarcoding) enables a simultaneous detection of fungi from multiple environmental samples. …”
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Spatial transcriptomic characteristics of gastric cancer in young and the expression and role of TMEM176B in gastric cancer cells by Zhenhua Jiang, Yongfeng Wang, Chi Zhang, Shuangyin Han

“…Abstract Background Gastric cancer in young (GCY) is increasing in incidence with poor prognosis. …”
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Green Synthesis of Zinc Oxide Nanoparticles as a Promising Nanomedicine Approach for Anticancer, Antibacterial, and Anti-Inflammatory Therapies by Hussien NA, Khalil MAEF, Schagerl M, Ali SS

“…Green synthesis of zinc oxide nanoparticles (ZnO-NPs) using plant extracts offers an eco-friendly and biocompatible alternative to traditional chemical methods. This study explores the synthesis of ZnO-NPs using Syzygium aromaticum (clove) bud extract (CBE) and evaluates their multifaceted biomedical potential, including anticancer, antibacterial, and anti-inflammatory properties.Methods: Clove bud extract-zinc oxide nanoparticles (CBE-ZnO-NPs) were synthesized and characterized using scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDX), Fourier-transform infrared spectroscopy (FTIR), dynamic light scattering (DLS), and Brunauer-Emmett-Teller (BET) analyses to confirm their size, morphology, elemental composition, and surface properties. …”
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The current status of nano-hydrogel preparations for osteochondral repair: Systematic Review by Abebe Feyissa Amhare, Abebe Feyissa Amhare, Lichun Qiao, Huan Deng, Jinyan Lin, Jun Wang, Wei Wang, Jing Han

“…This systematic review aims to evaluate current advancements in nano-hydrogel formulations for osteochondral repair, focusing on their composition, preparation methods, mechanical properties, biocompatibility, and regenerative outcomes.MethodsFollowing the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, a comprehensive literature search was conducted across PubMed, Web of Science, and Scopus. …”
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Socially inclusive valorization of gold mill tailings from the small-scale gold mining sector by R.M. Balanay, R.P. Varela, A. Balbin, M.A. Lavapiez

“…BACKGROUND AND OBJECTIVES: Gold mining wastes have long been a significant concern in Agusan del Sur, a gold mining district in the Philippines. …”
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The glycosaminoglycan chains of perlecan regulate the perivascular fluid transport by Abhishek Singh, Mika Kaakinen, Harri Elamaa, Vesa Kiviniemi, Lauri Eklund

“…Abstract Background The perivascular conduct pathway that connects the cerebrospinal fluid spaces with the interstitial fluid in the parenchyma are of importance for solute clearance from the brain. …”
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The phenology of Epilobium hirsutum L.: assessing marker compounds variability of a pharmaceutically important plant remedy by Olha Mykhailenko, Olha Mykhailenko, Olha Mykhailenko, Banaz Jalil, Kateryna Uminska, Liudas Ivanauskas, Zigmantas Gudžinskas, Michael Heinrich, Michael Heinrich

“…This study aimed to provide evidence-based data on the chemical composition of the species over a 1-year cycle and define the optimal harvesting period, which is essential to ensure consistency and efficacy in plant-derived products.MethodsThe phytochemical variability of E. hirsutum across habitats (mesic grassland, wet grassland, and lake shore), plant parts (leaves and stems), and phenological stages (from April to October) was investigated. …”
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Assessing Nutritional Knowledge and Physical Health Among Football Players: A Pilot Study from Three Sports Clubs in Western Romania by Gabriel Roberto Marconi, Brigitte Osser, Gyongyi Osser, Caius Calin Miuța, Csongor Toth, Viorel Petru Ardelean, Anca Dicu, Corina Dalia Toderescu, Laura Ioana Bondar

“…Background: Football players require optimal nutrition and physical fitness to enhance their performance and maintain their health. …”
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Unveiling viral diversity and dynamics in mosquitoes through metagenomic analysis in Guizhou Province, China by Yan Linghu, Rui-Si Hu, Xiao-Min Tang, Rong-Ting Li, Wei-Yi Li, Jia-Hong Wu

“…Abstract Background Poverty, disease, and vector ecology intersect to present ongoing health threats, particularly in ecologically sensitive regions. …”
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Single-cell sequencing combined with spatial transcriptomics reveals the characteristics of follicle-targeted inflammation patterns in primary cicatricial alopecia by Qitao Chen, Yuqian Li, Qilin Zhu, Zhongming Li, Guanghui Shao, Yanjun Liu, Peixuan Jiang, Qiuwei Tao, Lili Shen, Jing Zhu, Linwei Wei, Yanhua Li, Xufeng Du

“…Abstract Background Primary cicatricial alopecia (PCA) causes irreversible hair loss due to immune-mediated hair follicle destruction. …”
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Epigenetic signatures in surrogate tissues are able to assess cancer risk and indicate the efficacy of preventive measures by James E. Barrett, Chiara Maria Herzog, Sepideh Aminzadeh-Gohari, Elisa Redl, Isma Ishaq Parveen, Julia Rothärmel, Julia Tevini, Daniela D. Weber, Luca Catalano, Victoria E. Stefan, Thomas K. Felder, Peter Obrist, Twana Alkasalias, Kristina Gemzell-Danielsson, Roland Lang, Barbara Kofler, Martin Widschwendter

“…Methods Here we utilized medroxyprogesterone acetate and 7,12-dimethylbenzanthracene to induce mammary gland cancers in mice. …”
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Characteristics of cancer mycobiome in patients with acral melanoma by Lin Li, Qi Sun, Rong Huang, Zhengyun Zou, Jiayu Wang, Lianjun Zhao, Donglin Kang, Xinyu Su, Yirong Wu, Ziyao Xie

“…Background Intratumoral fungi have recently been implicated in cancer initiation and progression, with potential as biomarkers for predicting clinical outcomes and treatment response in patients with cancer. …”
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Is the flipped classroom more effective than the traditional classroom in clinical medical education: a systematic review and meta-analysis by Xu-Ying Shi, Qing Yin, Qiu-Wen Wang, Bing-Rui Lu, Guo-Xiang Li, Shu-Hong Huang, Zhi-Gang Sun

“…BackgroundThe flipped classroom teaching method has been increasingly adopted in recent years for teaching clinical medical specialties in medical schools around the world. …”
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Tackling the primary healthcare workforce crisis: time to talk about health systems and governance—a comparative assessment of nine countries in the WHO European region by Ellen Kuhlmann, Michelle Falkenbach, Monica Georgina Brînzac, Tiago Correia, Maria Panagioti, Bernd Rechel, Anna Sagan, Milena Santric-Milicevic, Marius-Ionuț Ungureanu, Iris Wallenburg, Viola Burau

“…Abstract Background Primary healthcare has emerged as a powerful global concept, but little attention has been directed towards the pivotal role of the healthcare workforce and the diverse institutional setting in which they work. …”
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Single-cell transcriptomic analyses reveal heterogeneity and key subsets associated with survival and response to PD-1 blockade in cervical squamous cell carcinoma by Xia Li, Zhao Zhao, Yanmei Cheng, Jiaqin Yan, Fang Ren, Yanyan Jia, Juanhua Li, Binhui Wang, Junqi Liu, Chenyin Wang, Meimei Gao, Hao Gu, Mingliang Fan, Huirong Shi, Mei Ji, Qitai Zhao

“…Methods In this study, we characterized 50,649 cells obtained from the CSCC for single-cell RNA sequencing and integrated bulk sequencing data from The Cancer Genome Atlas (TCGA) and clinical samples to explore their cell composition, metabolic processes, signaling pathways, specific transcription factors, lineage tracking and response to immunotherapy. …”
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Intermittent supplementation with Akkermansia muciniphila and galactooligosaccharides modulates Alzheimer’s disease progression, gut microbiota, and colon short-chain fatty acid pr... by Arnas Kunevičius, Akshay Kumar Vijaya, Alessandro Atzeni, Jonas Mingaila, Ieva Šimoliūnė, Rapolas Jamontas, Emilija Keževičiūtė, Miguel Gueimonde, Rolandas Meškys, Daiva Baltriukienė, Silvia Arboleya, Aurelijus Burokas

“…BackgroundBidirectional communication and mutual regulation between the gastrointestinal tract and the CNS is facilitated through the gut-brain axis. …”
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An Overview of the Etiopathogenic Mechanisms Involved in the Expression of the Oral Microbiota by Ion Alexandru Popovici, Cristian Ionut Orasanu, Georgeta-Camelia Cozaru, Anita-Cristina Ionescu, Lidia Kajanto, Bogdan Cimpineanu, Anca Chisoi, Adrian Nelutu Mitroi, Ionut Poinareanu, Raluca Ioana Voda, Oana Andreea Ursica, Mihaela Butcaru Pundiche

“…<b>Background/Objectives</b>: The diversity of the oral microbiota exerts its effects in maintaining dental and overall health. …”
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Comprehensive Characterization of Serum Lipids of Dairy Cows: Effects of Negative Energy Balance on Lipid Remodelling by Zhiqian Liu, Wenjiao Wang, Joanne E. Hemsworth, Coralie M. Reich, Carolyn R. Bath, Monique J. Berkhout, Muhammad S. Tahir, Vilnis Ezernieks, Leah C. Marett, Amanda J. Chamberlain, Mike E. Goddard, Simone J. Rochfort

“…Background: The presence and concentration of lipids in serum of dairy cows have significant implications for both animal health and productivity and are potential biomarkers for several common diseases. …”
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The Impact of Obesity on the Association between Parity and Risk of Type 2 Diabetes Mellitus by Yuki Gen, Kyuho Kim, Joonyub Lee, Junyoung Jung, Sang-Hyuk Jung, Hong-Hee Won, Dokyoon Kim, Yun-Sung Jo, Yu-Bae Ahn, Seung-Hyun Ko, Jae-Seung Yun

“…This study aims to explore the complex relationship between parity and T2DM risk, considering additional factors such as obesity, race, and body composition. Methods This prospective cohort study used data from 242,159 women aged 40 to 69 from the UK Biobank, none of whom had T2DM at baseline. …”
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