ARHGAP25: a novel player in the Pathomechanism of allergic contact hypersensitivity by Domonkos Czárán, Péter Sasvári, Kende Lőrincz, Krisztina Ella, Virág Gellén, Roland Csépányi-Kömi

“…Here, we investigate its role in the pathogenesis of the more complex inflammatory process of contact hypersensitivity.MethodsFor sensitization, the abdomens of wild-type and ARHGAP25 deficient (KO) mice on a C57BL/6 background, as well as bone marrow chimeric mice, were coated with 3% TNCB (2-chloro-1,3,5-trinitrobenzene) or acetone in the control group. …”
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Correlation analysis of tertiary lymphoid structure parameters with the prognosis of patients with locally advanced rectal cancer after neoadjuvant chemotherapy: a retrospective st... by Yingjian Jiang, Chuang Zhang, Yifei Hou, Bin Zhao, Binbin Cui

“…Abstract Background The tertiary lymphoid structures (TLSs) are positively correlated with the prognosis of many solid tumors, including colorectal cancer. …”
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Dried blood spot technique for dietary fat assessment in a human nutritional intervention focused on oily fish intake by Laura Garcia-Urtiaga, Ainara Cano, Mercedes Caro, Jaione Pagaldai, Javier Amezaga, Itziar Tueros, Sara Arranz

“…Abstract Background Several studies have employed dried blood spot (DBS) analysis to measure omega-3 levels in whole blood and investigate their associations with cardiovascular risk. …”
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Treatment with a Monoclonal Anti-IL-12p40 Antibody Induces Substantial Gut Microbiota Changes in an Experimental Colitis Model by Josué Castro-Mejía, Maja Jakesevic, Łukasz Krych, Dennis S. Nielsen, Lars H. Hansen, Bodil C. Sondergaard, Peter H. Kvist, Axel K. Hansen, Thomas L. Holm

“…Background and Aim. Crohn’s disease is associated with gut microbiota (GM) dysbiosis. …”
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Ecotoxicological insight of phytochemicals, toxicological informatics, and heavy metal concentration in Tridax procumbens L. in geothermal areas by N.B. Maulydia, R. Idroes, K. Khairan, T.E. Tallei, F. Mohd Fauzi

“…BACKGROUND AND OBJECTIVES: Tridax procumbens L. is a plant that grows abundantly in the Ie-Seu'um geothermal area in Aceh Province, Indonesia. …”
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Status of sleeping habits and its influence on growth and metabolism of children in Beijing: a population-based cross-sectional study by Yiren Chen, Lijun Wu, Zijun Liao, Yiying Huang, Qin Liu, Shaoli Li, Junting Liu, Xinnan Zong, Jun Tai, Fangfang Chen

“…Abstract Background Sleep disturbances are associated with poor health outcomes in children. …”
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Investigating Tropical Cyclone Warm Core and Boundary Layer Structures with Constellation Observing System for Meteorology, Ionosphere, and Climate 2 Radio Occultation Data by Xiaoxu Qi, Shengpeng Yang, Li He

“…This research provides an effective QC method and reveals that the bending angle is sensitive to the PBL height.…”
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Motion correction of simultaneous brain PET/MR images based on tracer uptake characteristics by Sheng-Chieh Chiu, Jose Angelo U. Perucho, Yu-Hua Dean Fang

“…In the retrospective human study, we evaluated the detectability of age-related amyloid burden in healthy controls under different co-registration methods as a demonstrative use case. TCBC significantly enhanced the detectability of age-related amyloid burden with stronger correlations across all five regions of evaluation, such as the medial orbitofrontal cortex (p < 0.001), precuneus (p = 0.004), and early amyloid-β composite (p = 0.002), compared to FSMC (p = 0.004, 0.007, and 0.006, respectively) and uncorrected (p = 0.378, 0.023, and 0.039, respectively) methods. …”
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Language Suggestion in Online Advertising of Figure Skating Ice Shows by O. A. Selemeneva

“…The analysis of media texts posted in the Russian social network “VKontakte” was carried out. 124 advertising texts for 2021—2023 were analyzed Methods of discursive and communicative-pragmatic analysis, content analysis, descriptive method were used. …”
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Thrombolytic and Anticoagulant Therapy for Pulmonary Embolism with High and Intermendiate Risk of Early Death. Part 3. An Effect on Pulmonary Perfusion with High and Intermediate R... by O. V. Nikitina, I. P. Mikhailov, N. Y. Kudryashova, E. V. Migunova, A. G. Dorfman, V. I. Avfukov

“…Background The advantage of thrombolytic therapy (TLT) over anticoagulant therapy(ACT) in patients with a high risk of early death (hemodynamic disorders) in acute pulmonary embolism is considered proven. …”
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Safety and Efficacy of Glucomannan for Weight Loss in Overweight and Moderately Obese Adults by Joyce K. Keithley, Barbara Swanson, Susan L. Mikolaitis, Mark DeMeo, Janice M. Zeller, Lou Fogg, Jehan Adamji

“…Background. Few safe and effective dietary supplements are available to promote weight loss. …”
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Disentangling the divergent causal pathways underlying the association between body mass index and bone mineral density: a comprehensive Mendelian randomization study by Xunying Zhao, Lin He, Xueyao Wu, Li Zhang, Jinyu Xiao, Changfeng Xiao, Yang Qu, Jingwei Zhu, Chenjiarui Qin, Deqin Huang, Pengyue Shen, Tao Han, Mengyu Fan, Jiayuan Li, Stephen Burgess, Xia Jiang

“…Abstract Background While the protective role of body mass index (BMI) in bone mass has been well-documented, the divergent associations between BMI and estimated bone mineral density (eBMD), attributed to its highly heterogeneous nature, remain insufficiently understood. …”
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Comprehensive characterization and valorization potential of Amazonian Sacha inchi (Plukenetia volubilis L.) seeds, oil, and oilcake by-products for sustainable food applications by Fernando E. Alejandro Ruiz, Julio F. Ortega Jácome, José R. Mora, Andrea C. Landázuri, Andrea C. Landázuri, Andrea C. Landázuri, Andrea C. Landázuri, Paola Vásconez Duchicela, Julio Vásconez Espinoza, Pablo Beltrán-Ayala, María J. Andrade-Cuvi, José M. Alvarez-Suarez, José M. Alvarez-Suarez

“…This study evaluates the bromatological, chemical, bioactive, and techno-functional properties of Sacha inchi seeds and their by-products from the Ecuadorian Amazon to assess their potential as functional ingredients in bakery applications.MethodsBromatological composition and color of Sacha inchi seeds and oilcake flour were determined. …”
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Identifying the quality markers and optimizing the processing of Gastrodiae rhizoma to treat brain diseases by Yan Fu, Qingqing Xu, Jinqiang Zhang, Chuanzhi Kang, Changgui Yang, Lumei Guo, Chenggang Zhang, Tao Zhou, Chenghong Xiao

“…Finally, a fit degree analysis was carried out using different composition ratios and proportions of the disease component degree value, and the therapeutic effects of different processing methods on Alzheimer’s disease, major depressive disorder, and cerebral ischemia were outlined clearly.ResultsWe identified 32 potential therapeutic components and screened 13 quality markers in GR, of which five quality markers (galactinol, glucosyringic acid, parishins C and E, and S-(4-hydroxybenzyl)-glutathione) showed efficacy against all three brain diseases. …”
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Randomised trial comparing weight loss through lifestyle and GLP-1 receptor agonist therapy in people with MASLD by Ahmad Moolla, Toryn Poolman, Nantia Othonos, Jiawen Dong, Kieran Smith, Thomas Cornfield, Sarah White, David W. Ray, Sofia Mouchti, Ferenc E. Mózes, Helena Thomaides-Brears, Stefan Neubauer, Jeremy F. Cobbold, Leanne Hodson, Jeremy W. Tomlinson

“…To dissect the mechanisms underpinning their benefits, we conducted a prospective, randomised, experimental medicine study in people with MASLD, comparing GLP-1RA treatment (liraglutide) to matched lifestyle-induced weight loss and assessed the impact of treatment withdrawal. Methods: Twenty-nine participants with MASLD, without type 2 diabetes underwent metabolic phenotyping including measurement de novo lipogenesis (DNL), liver magnetic resonance imaging, body composition, adipose tissue RNA sequencing, circulating proteome, and stool microbiome analysis. …”
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Antibacterial activity of selenium nanoparticles/copper oxide (SeNPs/CuO) nanocomposite against some multi-drug resistant clinical pathogens by Ahmed Morad Asaad, Sara A. Saied, Mohammad M. Torayah, N. I. Abu-Elsaad, Samah Mohammed Awad.

“…Methods The Se-NPs/Cu2O nanocomposite was fabricated using the chemical deposition method. …”
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Motor Imagery EEG Classification Based on Multi-Domain Feature Rotation and Stacking Ensemble by Xianglong Zhu, Ming Meng, Zewen Yan, Zhizeng Luo

“…Background: Decoding motor intentions from electroencephalogram (EEG) signals is a critical component of motor imagery-based brain–computer interface (MI–BCIs). …”
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Effects of Regular Habitual Exercise on Platelet Energetics in Male Recreational Contact Sports Student‐Athletes: A Cross‐Sectional Study by Tomoharu Mochizuki, Takashi Ushiki, Hiroshi Koga, Katsuya Suzuki, Misato Sato, Mami Osawa, Masami Kamimura, Hajime Ishiguro, Tatsuya Suwabe, Tomoyuki Kawase

“…Plasma lactate, platelet adenosine triphosphate (ATP), and oxygen (O2) consumption levels were quantified using biochemical and bioelectrical methods. Results The body composition indices of the CA generally showed characteristics that fell between those of professional athletes and the NA. …”
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Metagenomics-based analysis of microbial community structure and functional differences in fermented grains of Jiang-flavored baijiu from different production regions and policy re... by Jiaqi Shen, Jiaqi Shen, Yuanyan Hu, Yunjin Zhang, Lixia Li, Xiaofeng Deng, Manjing Chen, Laoda Li, Peiyun Xie, Mingbo Shao

“…Although the dominant microbial species were similar across regions, their relative abundances differed significantly. α-diversity analysis showed that grains from the Bijie region had higher species richness and evenness indices, indicating the significant impact of geographical location and the strong-flavor baijiu-brewing background on microbial structure and composition. Analysis of similarity and the Wilcoxon rank-sum test revealed significant differences in the microbial communities of different regions, and we identified genera with large differences in abundance, such as Desmospora and Kroppenstedtia among bacteria, and Pyrenophora and Blyttiomyces among fungi. …”
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Exploring the Causal Relationship Between Gut Microbiota and Pulmonary Artery Hypertension: Insights From Mendelian Randomization by Lihuang Su, Xinghong Wang, Ya Lin, Yiying Zhang, Dan Yao, Tongtong Pan, Xiaoying Huang

“…Background Research into the “gut–lung” axis links gut microbiota to pulmonary artery hypertension (PAH). …”
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