Dietary patterns derived by Gaussian graphical models and metabolic profiles among overweight and obese individuals by Reyhaneh Mokhtari Hemami, Mohammad Asghari-Jafarabadi, Mahdieh Abbasalizad Farhangi, Maedeh Alipour

“…Abstract Background: The increasing prevalence of metabolic syndrome (MetS) and its associated risk factors highlights the critical need to understand dietary patterns that influence health outcomes, particularly among overweight and obese individuals. …”
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Disulfiram-loaded nanovesicles hydrogel promotes healing of diabetic wound by Xingzi Sun, Hanxi Ding, Xingyu Li, Yongjian Wu, Xi Huang

“…Abstract Background Traditional methods for treating diabetic wounds are limited in effectiveness because of their long healing times, the risk of immune rejection, and susceptibility to infection. …”
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Multivariate Data Analysis to Assess Process Evolution and Systematic Root Causes Investigation in Tablet Manufacturing at an Industrial Scale—A Case Study Focused on Improving Tab... by Rita Mathe, Tibor Casian, Ioan Tomuta

“…The purpose of this work was to identify the root causes for the low and variable hardness of core tablets prepared using high-shear wet granulation through batch statistical modeling and to verify the short- and long-term effectiveness of the improvement actions. <b>Methods</b>: The novelty of this study is the use of multivariate methods for the complex assessment of a wide data set belonging to two proportional composition strengths, manufactured at an industrial scale, with different tablet shapes and sizes, with the aim of identifying inter-related active ingredient and process variables with the highest impact on hardness value and for defining optimal processing conditions leading to a robust product. …”
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A review on the versatile applications of plant-based essential oils in food flavoring, culinary uses and health benefits by Alissar Hassid, Mohamed Salla, Maha Krayem, Sanaa Khaled, Hussein F. Hassan, Sami El Khatib

“…The paper highlights their potential as natural preservatives, flavor enhancers, and bioactive agents, while also addressing challenges such as toxicity, allergenicity, and interactions with food components. Methods A comprehensive literature review was conducted to analyze studies on the extraction methods, chemical compositions, and biological activities of essential oils. …”
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Study of helminth eggs (Ascaris suum) inactivation by anaerobic digestion and electrochemical treatment [version 2; peer review: 1 approved, 2 approved with reservations] by Srikanth Mutnuri, Prajakta Pratap Patil

“…Background The use of insufficiently treated wastewater or Faecal sludge in agriculture raises concerns because of the pathogen content. …”
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Examining the dietary contributions of lipids to pancreatic cancer burden (1990–2021): incidence trends and future projections by Kexin Jiang, Zhirong Zhao, Mu Yuan, Hua Ji, Yiwen Zhao, Hanyu Ding, Jiajie Feng, Yongjiang Zhou, Ruiwu Dai

“…Abstract Background Pancreatic cancer (PC) ranks sixth globally among cancer deaths, imposing a significant burden on healthcare systems worldwide. …”
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Alteration of salivary Streptococcus is associated with statin therapy in older adults: a cohort study by Daisuke Hisamatsu, Yusuke Ogata, Wataru Suda, Yo Mabuchi, Yuna Naraoka, Taku Yamato, Akimi Ikeba, Kyoko Kumagai, Masahira Hattori, Masahira Hattori, Chihiro Akazawa

“…Therefore, in this study, we performed a multivariate analysis to investigate the relationship between salivary microbiomes and host variables, including prescribed drugs, cognitive function, and oral health, in Japanese older adults with different disease backgrounds.MethodsWe enrolled non-hospitalised 82 older adults aged ≥70 years from a Japanese village community, and collected metadata, including age, sex, body mass index, cognitive function, oral health, alcohol consumption, smoking, and common prescription drug information. …”
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Three-dimensional partitioning and quantification of orthodontic root resorption via automatic root extraction from cone-beam computed tomography by Jing Huang, Mengjie Wang, Xuan Tang, Leilei Zheng, Chongshi Yang

“…Methods Thirty-six patients with malocclusion were included and divided into two groups. …”
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Analysis of ductal carcinoma in situ by self-reported race reveals molecular differences related to outcome by Siri H. Strand, Kathleen E. Houlahan, Vernal Branch, Lorraine M. King, Thomas Lynch, Belén Rivero-Guitiérrez, Bryan Harmon, Fergus Couch, Kristalyn Gallagher, Mark Kilgore, Shi Wei, Angela DeMichele, Tari King, Priscilla McAuliffe, Christina Curtis, Kouros Owzar, Jeffrey R. Marks, Graham A. Colditz, E. Shelley Hwang, Robert B. West

“…Abstract Background Ductal carcinoma in situ (DCIS) is a non-obligate precursor to invasive breast cancer (IBC). …”
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Developing predictive models for tocilizumab response in rheumatoid arthritis: a gene expression and machine learning approaches by Weiya Lan, Wei Du, Wukai Ma, Xueming Yao, Zong Jiang, Jing Zhou, Changming Chen, Chunxia Wang, Fang Tang

“…Background: Rheumatoid arthritis (RA) is a chronic autoimmune disease treated with tocilizumab in patients unresponsive to methotrexate. …”
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Morinda officinalis oligosaccharides alleviate chronic unpredictable mild stress-induced depression through the BDNF/TrkB/CREB pathway and symptoms of sexual dysfunction in mice by Mengjie He, Mengying Hu, Tingqiao Wang, Zeping Zuo, Hongkai Li, Zhiwei Zhao, Yunwen Hao, Xueling Dai, Jianfang Wang, Yaxuan Sun

“…The aim of this study was to investigate the potential effects of Morinda officinalis oligosaccharides (MOO) on depression and its concomitant symptom, sexual dysfunction.MethodsChronic unpredictable mild stress (CUMS)-induced depression model was constructed, and the effects of MOO on depression and sexual abilities were evaluated.ResultsThe results revealed that MOO was able to alleviate CUMS-induced depression-like behavior in mice, to inhibit hippocampal neuron apoptosis, to reverse monoamine neurotransmitter imbalance, increase Brain-derived neurotrophic factor (BDNF) expression levels in the hippocampus, to modulate the composition and distribution of gut microbiota, and to increase the abundance of probiotics after continuous gavage of MOO for 28 days. …”
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Recent progress of interface modification of layered oxide cathode material for sodium‐ion batteries by Luyi Sun, Jun Zeng, Xuanhong Wan, Chenxi Peng, Jiarui Wang, Chongjia Lin, Min Zhu, Jun Liu

“…Finally, we will summarize various interface modification methods including surface engineering, doping modification and electrolyte composition which are aimed to improve interface stability of layered cathodes, perspectives of future research on layered cathodes are mentioned to provide some theoretical proposals.…”
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Surface Functionalized Polyhydroxyalkanoate Nanoparticles via SpyTag–SpyCatcher System for Targeted Breast Cancer Treatment by Jin Young Heo, Min Kyung Sung, Seonhye Jang, Hansol Kim, Youngdo Jeong, Dong-Jin Jang, Sang-Jae Lee, Seong-Bo Kim, Sung Tae Kim

“…<b>Background/Objectives:</b> Biodegradable polymers have emerged as promising platforms for drug delivery. …”
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Gut microbiome in neuropsychiatric disorders by Diana Marcela MEJÍA-GRANADOS, Benjamín VILLASANA-SALAZAR, Ana Carolina COAN, Liara RIZZI, Marcio Luiz Figueredo BALTHAZAR, Alexandre Barcia de GODOI, Amanda Morato do CANTO, Douglas Cescon da ROSA, Lucas Scárdua SILVA, Rafaella do Rosario TACLA, Alfredo DAMASCENO, Amanda DONATTI, Wagner Mauad AVELAR, Alessandro SOUSA, Iscia LOPES-CENDES

“…ABSTRACT Background: Neuropsychiatric disorders are a significant cause of death and disability worldwide. …”
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Gut microbial communities in chronic rhinosinusitis patients in response to 1,8-Cineol treatment by Simon Graspeuntner, Mathias Heidemann, Stephanie Jeschke, Mariia Lupatsii, Zuzana Penxova, Sven Künzel, Barbara Wollenberg, Anke Leichtle, Michael Ploch, Karl-Ludwig Bruchhage, Ralph Pries

“…Background: Chronic rhinosinusitis (CRS) is a widespread inflammatory disease of the paranasal sinuses and the standard treatment includes surgery and the administration of corticosteroids or antibiotics. …”
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Reduced abundance of Fusobacterium signifies cardiovascular benefits of sodium glucose cotransporter 2 inhibitor in type 2 diabetes: a single arm clinical trial by Shuhui Yang, Jiankun Deng, Xiaoxu Weng, Zhaojie Ma, Nie Lin, Yili Xiao, Rui Zuo, Yufei Hu, Canbin Zheng, Xiaoshan Zeng, Qimao Lin, Kaijian Hou, Kaijian Hou

“…BackgroundThe sodium glucose cotransporter 2 inhibitor (SGLT2i) dapagliflozin has been demonstrated cardiovascular benefits in patients with type 2 diabetes mellitus (T2DM). …”
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Association of antibody and T cell receptor repertoires in Trypanosoma cruzi infected rhesus macaques and host response to infection by Rachel M. Clear, Weihong Tu, Kelly Goff, Preston A. Marx, Claudia Herrera, Eric Dumonteil

“…We tested for differences in immunoglobulin (Ig) and T cell receptor (TCR) repertoires and their association with T. cruzi parasite diversity (i.e. the cruziome) and host responses in naturally infected rhesus macaques. Methods Ig and TCR complementarity-determination region (CDR)3 sequences were identified from RNA-sequencing data from peripheric blood mononuclear cells of T. cruzi infected rhesus macaques and analyzed for composition and diversity. …”
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Description of the Human Penile Urethra Epithelium by Matisse Duval, David Brownell, Stéphane Chabaud, Alexis Laungani, Eric Philippe, Stéphane Bolduc

“…<i>Background and Objectives</i>: The male urethra is a complex structure that plays a critical role in genitourinary health and function. …”
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Medium- and Short-Term Interventions with Ma-Pi 2 Macrobiotic Diet in Type 2 Diabetic Adults of Bauta, Havana by Carmen Porrata-Maury, Manuel Hernández-Triana, Eduardo Rodríguez-Sotero, Raúl Vilá-Dacosta-Calheiros, Héctor Hernández-Hernández, Mayelín Mirabal-Sosa, Concepción Campa-Huergo, Mario Pianesi

“…Background. In Cuba, the Ma-Pi 2 macrobiotic diet has shown positive results in 6-month assays with type 2 diabetic patients. …”
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Essential Oils from <i>Papaver rhoeas</i> and Their Metabolomic Profiling by Valeria Cavalloro, Francesco Saverio Robustelli della Cuna, Alberto Malovini, Carla Villa, Cristina Sottani, Matteo Balestra, Francesco Bracco, Emanuela Martino, Simona Collina

“…<b>Background/Objectives</b>: Essential oils (EOs) have been exploited by humans for centuries, but many sources remain poorly investigated, mainly due to the low yields associated with conventional extraction. …”
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