Aspirin inhibits proteasomal degradation and promotes α-synuclein aggregate clearance through K63 ubiquitination by Jing Gao, Yang Liu, Chenfang Si, Rui Guo, Shouqiao Hou, Xiaosong Liu, Houfang Long, Di Liu, Daichao Xu, Zai-Rong Zhang, Cong Liu, Bing Shan, Christoph W. Turck, Kaiwen He, Yaoyang Zhang

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The impact of food-based incentive behaviors on oral health among Saudi children: a cross-sectional study by Yasir Dilshad Siddiqui, Saud Hamdan Almaeen, Ahmed Shawkat Hashem, Ahmed Ali Ahmed Almuntashiri, Mohammed Nadeem Baig, Abdullah Hammad Alshammari, Rital Jamal Alwaqid, Haifa Ali Almutairi, Raha Ahmed, Rakhi Issrani, Farooq Ahmad Chaudhary

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Dose-response associations of device-measured sleep regularity and duration with incident dementia in 82391 UK adults by Wenxin Bian, Raaj K. Biswas, Matthew N. Ahmadi, Yu Sun Bin, Svetlana Postnova, Andrew J. K. Phillips, Nicholas A. Koemel, Jean-Philippe Chaput, Shantha M. W. Rajaratnam, Peter A. Cistulli, Emmanuel Stamatakis

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Innovations in Medical Education in Gastrointestinal Surgery Using Interactive Anatomical Tables by A. D. Kashtanov, E. O. Stetsyk, S. S. Dydykin, O. V. Kytko, E. M. Trunin, O. Yu. Aleshkina, A. N. Lavrentieva, A. N. Andreeva, D. S. Alekseeva, A. A. Muratova, A. Yu. Kharina, V. V. Tatarkin, A. S. Sokolova, V. N. Filatov, I. L. Samodova, E. A. Makeeva, E. S. Pekeldina, M. Yu. Kapitonova, T. S. Bikbaeva, I. A. Polkovova, B. A. Volel, T. M. Litvinova, E. N. Dudnik, N. V. Kireeva, K. V. Ivashkin, Yu. L. Vasil’ev

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Diagnostics and Treatment of Esophageal Achalasia (Clinical Guidelines of the Russian Gastroenterological Association, Russian Scientific Medical Society of Internal Medicine, Russ... by V. T. Ivashkin, A. S. Trukhmanov, I. V. Maev, O. M. Drapkina, A. I. Martynov, O. A. Storonova, E. A. Godgello, M. P. Korolev, T. L. Lapina, P. V. Pavlov, A. V. Paraskevova, I. A. Tarasova, E. D. Fedorov, A. T. Tskhovrebov, M. P. Shapka, A. L. Shestakov, A. V. Yurasov

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Evaluation and practical application of prompt-driven ChatGPTs for EMR generation by Hanlin Ding, Wenjie Xia, Yujia Zhou, Lei Wei, Yipeng Feng, Zi Wang, Xuming Song, Rutao Li, Qixing Mao, Bing Chen, Hui Wang, Xing Huang, Bin Zhu, Dongyu Jiang, Jingyu Sun, Gaochao Dong, Feng Jiang

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Comprehensive analysis of antimicrobial resistance dynamics among broiler and duck intensive production systems by Zsombor Szoke, Peter Fauszt, Maja Mikolas, Peter David, Emese Szilagyi-Tolnai, Georgina Pesti-Asboth, Judit Rita Homoki, Ildiko Kovacs-Forgacs, Ferenc Gal, Laszlo Stundl, Levente Czegledi, Aniko Stagel, Sandor Biro, Judit Remenyik, Melinda Paholcsek

“…Tetracycline and phenicol resistances emerged as the most prevalent. 13 high-resistance carrier (HRC) species were shared between both hosts. …”
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VSIG4+ tumor-associated macrophages mediate neutrophil infiltration and impair antigen-specific immunity in aggressive cancers through epigenetic regulation of SPP1 by Zongfu Pan, Jinming Chen, Tong Xu, Anqi Cai, Bing Han, Ying Li, Ziwen Fang, Dingyi Yu, Shanshan Wang, Junyu Zhou, Yingying Gong, Yulu Che, Xiaozhou Zou, Lei Cheng, Zhuo Tan, Minghua Ge, Ping Huang

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Hydroxocobalamin for the treatment of vasoplegia after lung transplantation: A case series by Anh Nguyen, MD, PhD, Rima Bouajram, PharmD, Marek Brzezinski, MD, Sahand Hassanipour, David Gordon, Binh Trinh, MD, Tobias Deuse, MD, Aida Venado, MD, Steve Hays, MD, Jonathan Singer, MD, Jasleen Kukreja, MD, MPH

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Discrete vulnerability to pharmacological CDK2 inhibition is governed by heterogeneity of the cancer cell cycle by Vishnu Kumarasamy, Jianxin Wang, Michelle Roti, Yin Wan, Adam P. Dommer, Hanna Rosenheck, Sivasankar Putta, Alec Trub, John Bisi, Jay Strum, Patrick Roberts, Seth M. Rubin, Costakis Frangou, Karen McLean, Agnieszka K. Witkiewicz, Erik S. Knudsen

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Mimosapudica L. aqueous extract protects mice against pilocarpine–picrotoxin kindling-induced temporal lobe epilepsy, oxidative stress, and alteration in GABAergic/cholinergic path... by Hart Mann Alain Youbi Mambou, Simon Pale, Orelien Sylvain Mtopi Bopda, Vanessa Tita Jugha, Nji Seraphin Ombel Musa, Tambong Ako Ojongnkpot, Bertrand Yuwong Wanyu, Raymond Bess Bila, Rashed N. Herqash, Abdelaaty A. Shahat, Germain Sotoing Taiwe

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Rice genotypes (Oryza sativa) respond to varying planting dates and environmental conditions by 1Asif Ali Kaleri, 1Danish Manzoor,1Rabia Laghari,2Muzamil Awan, 3Bina Khanzada, 4Hafsa Munir, 2Saba Solangi, 2Tameer Hyder Shah.5Ameer Jan, 6Laiba Ashfaq, 2Ghulam Sajjad Kaleri Kaleri

“… An essential food crop with a big role in the global economy is rice (Oryza sativa L.). …”
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TOPBP1 as a potential predictive biomarker for enhanced combinatorial efficacy of olaparib and AZD6738 in PDAC by Xiao-Mei Tang, Min-Min Shi, Jia-Cheng Wang, Yi-Jin Gu, Yu-Ting Dai, Qin-Xin Yang, Jia Liu, Ling-Jie Ren, Xin-Yun Liu, Chun Yang, Fang-Fang Ma, Ji-Bing Liu, Hong Yu, Da Fu, Yun-Feng Wang

“…Abstract Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive and often lethal malignancy, requiring the development of enhanced therapeutic approaches. …”
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Bellek Mekânı Olarak Belgesel Sinema: Kapalıçarşı’da Kırk Bin Adım Filminde İnsan, Mekân ve Eşya by Ayşe Gül Toprak Ökmen

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Revealing viral hepatitis epidemiology in the Democratic Republic of Congo: insights from yellow fever surveillance reanalysis by Patrick Mukadi-Kakoni, Yannick Munyeku-Bazitama, Gracia Kashitu-Mujinga, Marguerite Manwana-Pemba, Niclette Zenga-Bibi, Patient Okitale-Talunda, Christelle Mbelu-Kabongo, Fleurette Domai-Mbuyakala, Elisabeth Pukuta-Simbu, Pierre Mutantu-Nsele, Yoshinao Kubo, Sheila Makiala-Mandanda, Steve Ahuka-Mundeke, Koya Ariyoshi, Jean-Jacques Muyembe-Tamfum

“…Samples from individuals testing negative for yellow fever were tested for IgM antibodies against HAV, HBc, HCV, and HEV and HBs antigen using validated ELISA kits. …”
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Guidance for the clinical management of infants born to mothers with suspected/confirmed COVID-19 in Singapore by Kee Thai Yeo, Agnihotri Biswas, Selina Kah Ying Ho, Juin Yee Kong, Srabani Bharadwaj, Amutha Chinnadurai, Wai Yan Yip, Nurli Fadhillah Ab Latiff, Bin Huey Quek, Cheo Lian Yeo, Yvonne Peng Mei Ng, Kenny Teong Tai Ee, Mei Chien Chua, Woei Bing Poon, Zubair Amin

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Activating PKC-ε induces HIV expression with improved tolerability. by Alivelu M Irrinki, Jasmine Kaur, Bally Randhawa, Ryan McFadden, Chelsea Snyder, Hoa Truong, Daniel Soohoo, Eric Hu, Helen Yu, Bernard P Murray, Bing Lu, Dmytro Kornyeyev, Ishak Darryl Irwan, Lan Nguyen, Yu-San Yang, Jean-Philippe Belzile, Uli Schmitz, Todd C Appleby, Brian Schultz, Jay Lalezari, Steven Deeks, Tomas Cihlar, Jeffrey P Murry

“…Differential expression analysis indicated that PKC-ε and PKC-η isoforms are expressed at high levels in human CD4+ T cells but not in platelets. …”
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An abundant ginger compound furanodienone alleviates gut inflammation via the xenobiotic nuclear receptor PXR in mice by Xiaojuan Wang, Guohui Zhang, Zhiwei Bian, Vimanda Chow, Marina Grimaldi, Coralie Carivenc, Savannah Sirounian, Hao Li, Lucia Sladekova, Stefano Mott, Yulia Luperi, Yufeng Gong, Cait Costello, Linhao Li, Matthew Jachimowicz, Miao Guo, Shian Hu, Derek Wilson, Patrick Balaguer, William Bourguet, Sridhar Mani, Laura Bonati, Hui Peng, John March, Hongbing Wang, Shengpeng Wang, Henry M. Krause, Jiabao Liu

“…In this study, we find that a major ginger component, furanodienone (FDN), is a selective pregnane X receptor (PXR) ligand with agonistic transcriptional outcomes. We show that FDN binds within a sub-pocket of the PXR ligand binding domain (LBD), with subsequent alterations in LBD structure. …”
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Altered thermal preference by preoptic estrogen receptor alpha neurons in postpartum females by Nan Zhang, Meng Yu, Qianru Zhao, Bing Feng, Yue Deng, Jonathan C. Bean, Qingzhuo Liu, Benjamin P. Eappen, Yang He, Kristine M. Conde, Hailan Liu, Yongjie Yang, Longlong Tu, Mengjie Wang, Yongxiang Li, Na Yin, Hesong Liu, Junying Han, Darah Ave Threat, Nathan Xu, Taylor Smiley, Pingwen Xu, Lulu Chen, Tianshu Zeng, Yanlin He, Chunmei Wang

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