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Digital sleep phenotype and wrist actigraphy in individuals at clinical high risk for psychosis and people with schizophrenia spectrum disorders: a systematic review and meta-analysis
Published 2025-02-01“…Additionally, CHR-P individuals exhibited reduced sleep efficiency (MD −2.04% (−3.55 to 0.53)), whereas SSD participants had increased TIB (MD 121.58 min (88.16 to 155.00)) and sleep latency (MD 13.05 min (2.11 to 24.00)). The risk-of-bias assessment ranged from some concerns to high risk.Conclusions Our analyses identified sleep abnormalities in CHR-P and SSD compared with placebo. …”
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Assessment and enhancement of transfer capability for large-scale renewable generation base transmitted by voltage source converter based high voltage direct current system
Published 2025-04-01Subjects: “…Voltage source converter based high voltage direct current…”
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Long-term efficacy and safety of alemtuzumab in participants with highly active MS: TOPAZ clinical trial and interim analysis of TREAT-MS real-world study
Published 2025-02-01“…Background: Alemtuzumab is a disease-modifying therapy for highly active relapsing-remitting multiple sclerosis (RRMS). …”
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Research and insights for application of CO2-ECBM technology in deep high-rank coal seams: a case study of Jinzhong block, Qinshui Basin
Published 2025-01-01Subjects: Get full text
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A quality control method based on physical constraints and data-driven collaborative artificial intelligence for wind observations along high-speed railway lines
Published 2025-02-01“…Through the PD-BX method, the RMSE of the railway anemometer was reduced by 2.497 from 2.790 to 0.293, achieving quality control of wind observations along the high-speed railway lines and providing reliable results for improving the accuracy of the high-speed railway early warning system.…”
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Enhanced characterization of non-metallic inclusions in ultra-high-strength steels using advanced synchrotron-based X-ray absorption spectroscopy and chemometric analysis
Published 2025-03-01“…This study leverages synchrotron radiation-based X-ray absorption photoemission electron microscopy (X-PEEM) to investigate non-metallic inclusions (NMIs) in ultra-high-strength steels. By acquiring Ca-L2,3-edge X-ray absorption spectra from six NMIs at both room temperature and 400 °C, we analyze their structural changes, chemical compositions, and phase transformations. …”
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Combination gemcitabine and PD-L1xCD3 bispecific T cell engager (BiTE) enhances T lymphocyte cytotoxicity against cholangiocarcinoma cells
Published 2022-04-01“…Two recombinant PD-L1xCD3 BiTEs (mBiTE and sBiTE contain anti-PD-L1 scFv region from atezolizumab and from a published sequence, respectively) were able to specifically bind to both CD3 on T lymphocytes, and to PD-L1 overexpressed after gemcitabine treatment on CCA (KKU213A, KKU055, and KKU100) cells. mBiTE and sBiTE significantly enhanced T lymphocyte cytotoxicity against CCA cells, especially after gemcitabine treatment, and their magnitudes of cytotoxicity were positively associated with the levels of PD-L1 expression. …”
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Effects of high-intensity interval training on physical performance, systolic blood pressure, oxidative stress and inflammatory markers in skeletal muscle of spontaneously hypertensive rats.
Published 2025-01-01“…<h4>Aim</h4>To investigate whether high-intensity interval training (HIIT) improves physical performance, systolic blood pressure, and markers of oxidative stress and inflammation in skeletal muscle of spontaneously hypertensive rats (SHR).…”
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Preparation of doped spinel LiMn2O4 cathode using α-MnO2 for high-performance Li-ion batteries
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Efficacy of high-dose steroids versus low-dose steroids in the treatment of immune checkpoint inhibitor-associated myocarditis: a case series and systematic review
Published 2025-02-01“…The primary aim was to compare clinical outcomes and therapeutic responses between patients treated with high-dose versus low-dose methylprednisolone.ResultsPatients receiving an initial high-dose intravenous methylprednisolone (1 g/day) exhibited a more rapid reduction in myocardial injury markers, including troponin I/T (cTnI/T), creatine kinase (CK), and N-terminal pro b-type natriuretic peptide (NT-proBNP), compared to those receiving lower doses. …”
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Global, regional, and national disease burden attributable to high systolic blood pressure in youth and young adults: 2021 Global Burden of Disease Study analysis
Published 2025-02-01“…Abstract Background High systolic blood pressure (HSBP) can cause adverse cardiovascular events and is therefore associated with a heavy global disease burden. …”
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PENGEMBANGAN SISTEM KOMBINASI KERJA REM, STEER, DAN TRAKSI BERBASIS LiDAR 3D UNTUK KENDARAAN LISTRIK OTONOM RODA TIGA
Published 2024-07-01“… Selama beberapa waktu terakhir, pengembangan sistem deteksi objek berbasis LiDAR telah menjadi fokus utama bagi para pengembang kendaraan listrik otonom. Banyak upaya telah dilakukan untuk meningkatkan dan mengoptimalkan teknologi ini guna mencapai mobilitas otonom yang lebih canggih dan aman. …”
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‘I haven’t met them, I don’t have any trust in them. It just feels like a big unknown’: a qualitative study exploring the determinants of consent to use Human Fertilisation and Embryology Authority registry data in research
Published 2019-05-01“…Public understanding of data use and security is relatively poor; increased public trust in, and awareness of, research based on routine data could improve consent to data use and reduce the risk of bias.…”
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The Economic Benefits Associated with Florida's Artificial Reefs
Published 2006-08-01Get full text
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