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3101
Inducers of Autophagy and Cell Death: Focus on Copper Metabolism
Published 2025-01-01“…According to recent research, copper can bind to lipoylation sites on proteins involved in the tricarboxylic acid cycle, causing aggregation of lipoylated proteins, the loss of Fe-S cluster proteins, proteotoxic stress, and ultimately, cell death. …”
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3102
A visual cortical-lateral posterior thalamic nucleus circuit regulates depressive-like behaviors in male mice
Published 2025-02-01“…Abstract Depression, a prevalent psychiatric disorder of ambiguous etiology and high heterogeneity, has been recently linked to the primary visual cortex (V1). …”
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3103
Modern concept of bacterial complications at liver cirrhosis
Published 2010-12-01“…Various methods of prophylaxis, including the use of antibiotics, pre- and probiotics, bile acids can be applied to alter bacterial overgrowth and bacterial translocation. …”
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3104
Antiemetic activity of Sesamol possibly through serotonergic and dopaminergic receptor interaction pathways: In vivo and in silico studies
Published 2025-03-01“…An in-silico study showed SEL has moderate binding activity (−5.9 and − 5.7 kcal/mol) for serotonin (5HT3) and dopaminergic (D2) receptors, respectively, via hydrogen and hydrophobic bonds with specific amino acid residues.…”
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3105
Corrosion behavior and mechanism of Cr and Cu alloy weathering steel in simulated marine atmospheric environment
Published 2025-03-01“…The corrosion mechanism indicates that Cr and Cu initially promote corrosion by forming oxides, but as corrosion progresses, Cr binds with α-FeOOH to form dense oxides like FeCr₂O₄ and α-(Fe, Cr)OOH, which protect the steel by limiting access to corrosive media.…”
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3106
Targeting adipocyte ESRRA promotes osteogenesis and vascular formation in adipocyte-rich bone marrow
Published 2024-05-01“…Pharmacological inhibition of ESRRA protects obese mice against bone loss and high marrow adiposity. Thus, our findings highlight a therapeutic approach via targeting adipocyte ESRRA to preserve bone formation especially in detrimental adipocyte-rich bone milieu.…”
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3107
Peripheral membrane protein endophilin B1 probes, perturbs and permeabilizes lipid bilayers
Published 2025-02-01“…Abstract Bin/Amphiphysin/Rvs167 (BAR) domain containing proteins are peripheral membrane proteins that regulate intracellular membrane curvature. …”
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3108
ROS-induced cytosolic release of mitochondrial PGAM5 promotes colorectal cancer progression by interacting with MST3
Published 2025-02-01“…Cytosolic PGAM5 then directly binds to and dephosphorylates MST3 kinase. This, in turn, prevents STK25-mediated LATS1/2 phosphorylation, leading to YAP activation and CRC progression. …”
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3109
The Relevance of Biblical Exegesis to the Study of the Dynamics of the Educational Relationship in Contemporary Pedagogy. An Example of the Biblical Story of the Calling of Levi
Published 2025-01-01“…Pedagogues analysing the role of theology in pedagogical sciences often see theology as the basis for making moral recommendations derived primarily from the Revelation contained in the Bible. This approach minimises the relevance of biblical sciences to pedagogy while narrowing the perspective of its research areas. …”
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3110
BREAKING GENDER STEREOTYPES: A CRITICAL APPRAISAL OF BARRIERS TO EFFECTIVE COMMUNICATION
Published 2023-09-01“…The paper, therefore, recommends that it is important to be aware of the ways that gender stereotypes can impact communication by first, examining our own biases and assumptions as individuals, and organisations, about gender roles in communication. …”
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3111
Las Dinámicas del Sistema Penal Acusatorio en el Marco del Preacuerdo como Mecanismo de Terminación Anticipada
Published 2025-02-01“…Lo que ha permitido concluir que, el sistema penal acusatorio es un modelo que ha concretado una serie de garantías en aras de consolidar la protección de bienes jurídicos no sólo a través de la persecución penal; sino que través de la flexibilización en el marco procesal sin que ello implique la renuncia a la persecución penal. …”
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3112
Effects of orthography presentation and loanword frequency on L2 speech shadowing
Published 2025-06-01“…These findings are discussed in terms of implications for episodic memories, category activation, spreading-activation, and production biases.…”
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3113
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3114
Praising God or singing of love? From theological to erotic allegorisation in the interpretation of Canticles
Published 2010-06-01“…Alongside a literal reading of the text, there is also the possibility of an allegorical interpretation, which was often, consciously or otherwise, a reaction against a literal reading of the Bible. Although this contrast between the terms ‘literal’ and ‘allegorical’ appears frequently in the literature on Canticles, the present article argues that this terminology seems to be inadequate for Canticles at any rate: reading Canticles either ‘literally’ or ‘allegorically’ is an expression of a false dilemma with respect to this book. …”
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3115
THE IMPLICATIONS OF TERRORISM ON FOOD PRICES IN NIGERIA
Published 2024-07-01“…In view of these occurrences , this paper examines the implications of terrorism on the recent prices of food and our empirical results shows that terrorism has a negative effect on the prices of food in the country .The study adopted the descriptive analysis of secondary data to examine the effects of terrorism on food prices in the nation .The study will examine the topic in detail and based on this ,the following policy recommendations will be put forward which includes government providing securities for farmers by using the non-biased military to silent the insurgents, adopt a registration data of herders with government which will capture all operating herders in Nigerian states for easy tracking of any misbehavior, provide employment for our jobless youths who had become instruments in the hands of terrorist promoters, and above all, Nigerian government should adopt State police for a better protection of our rural areas and communities. …”
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3116
Orbital-order as the driving mechanism for superconductivity in ruthenates
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3117
Ocean stratification impedes particulate transport to the plumes of Enceladus
Published 2025-02-01“…This suggests that either timescales of several months, inferred from Cassini observations, are incorrect, perhaps biased by alternative particulate transport mechanisms, or that Enceladus’ ice shell is not in a quasi-equilibrated state.…”
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3118
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3119
PRRSV-2 nsp2 Ignites NLRP3 inflammasome through IKKβ-dependent dispersed trans-Golgi network translocation.
Published 2025-01-01“…Mechanistically, PRRSV-2 nsp2 interacts with the nucleotide-binding and oligomerization (NACHT) domain of NLRP3, augmenting IKKβ recruitment to driving NLRP3 translocation to the dispersed trans-Golgi network (dTGN) for oligomerization. …”
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3120
The history of landfills and landfill gas management in the U.S.
Published 2024-02-01“…Eight out the top ten states with high recycling rates have high landfill costs, and nine of the top ten states with high recycling rates also have bottle bill legislation that requires a deposit on bottles. …”
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